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The map label for this gene is dnaQ [H]

Identifier: 187929152

GI number: 187929152

Start: 2182803

End: 2183531

Strand: Reverse

Name: dnaQ [H]

Synonym: Rpic_2073

Alternate gene names: 187929152

Gene position: 2183531-2182803 (Counterclockwise)

Preceding gene: 187929153

Following gene: 187929151

Centisome position: 55.38

GC content: 65.57

Gene sequence:

>729_bases
ATGCGACAGATCATTCTCGATACCGAAACCACCGGCCTGAATGCCGCCACGGGCGACCGCGTGATCGAAATCGGTTGCGT
GGAGATGGTCAACCGCCGCCTGACCGGCCGGAACCTGCACTTCTACATCAACCCGGAGCGTGAGATCGACGCGGGCGCGA
TGGCTGTGCACGGCATCACCAACGAGTTCGTGGCTGACAAGCCGAAGTTCGCCGAGATCGTCAACGAGATCCGCGACTAC
GTGCAGGGCGCCGAAGCGATCATCCACAACGCCGCGTTCGACTTGGGCTTCCTGGACATGGAATTCCAGCGCCTGGGCCT
GCCAGCCTTCCGTGAGCACCTCTCGGGCCACATCGACACGCTGCGCGAGGCGCGCCAGATGTTCCCTGGCAAGCGCAACT
CGCTGGATGCGCTGTGCGACCGTCTGGGCGTGAGCAACGCGCACCGTACGCTGCACGGCGCACTGCTGGATGCGGAACTG
CTGGCCGAGGTCTACCTCGCCATGACGCGCGGCCAGAACACGCTGGTGATCGACATGCTGGAGTCGGGCGAGGGCGCGTC
GGCCGAAGCCGTTGCCGTCGACCTGAGCGCGTTGCAACTGCCGGTGCTGCTGGCGACCGAAGCGGAGGCCGAAGCGCACG
CCGGCGTGCTCAAGGAGATCGACAAGGCCAGCGGCGGCAAGACCGTTTGGACGCGTGAACCCGTGGAATCTGCGCAGCCG
GCTGCCTGA

Upstream 100 bases:

>100_bases
CGCTGGCCCGCGCCGTGAAGTGGCATGCGGAACACCGCATCCTGCTCAACGGCCACAAGACCGTCGTCTTCAAGTAATCC
AGTCAGAGTAGGGGAGCGCG

Downstream 100 bases:

>100_bases
TCAAAAAAATGTGCGGTCAGGGTATTTACACGGCTGCACCTTTTCGCCATAATCTCGTTTTCACCGCATTCGGGTGGTTA
GCTCAGCGGTAGAGCACTGC

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MRQIILDTETTGLNAATGDRVIEIGCVEMVNRRLTGRNLHFYINPEREIDAGAMAVHGITNEFVADKPKFAEIVNEIRDY
VQGAEAIIHNAAFDLGFLDMEFQRLGLPAFREHLSGHIDTLREARQMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAEL
LAEVYLAMTRGQNTLVIDMLESGEGASAEAVAVDLSALQLPVLLATEAEAEAHAGVLKEIDKASGGKTVWTREPVESAQP
AA

Sequences:

>Translated_242_residues
MRQIILDTETTGLNAATGDRVIEIGCVEMVNRRLTGRNLHFYINPEREIDAGAMAVHGITNEFVADKPKFAEIVNEIRDY
VQGAEAIIHNAAFDLGFLDMEFQRLGLPAFREHLSGHIDTLREARQMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAEL
LAEVYLAMTRGQNTLVIDMLESGEGASAEAVAVDLSALQLPVLLATEAEAEAHAGVLKEIDKASGGKTVWTREPVESAQP
AA
>Mature_242_residues
MRQIILDTETTGLNAATGDRVIEIGCVEMVNRRLTGRNLHFYINPEREIDAGAMAVHGITNEFVADKPKFAEIVNEIRDY
VQGAEAIIHNAAFDLGFLDMEFQRLGLPAFREHLSGHIDTLREARQMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAEL
LAEVYLAMTRGQNTLVIDMLESGEGASAEAVAVDLSALQLPVLLATEAEAEAHAGVLKEIDKASGGKTVWTREPVESAQP
AA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=236, Percent_Identity=50.4237288135593, Blast_Score=227, Evalue=7e-61,
Organism=Escherichia coli, GI1788149, Length=243, Percent_Identity=27.1604938271605, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26326; Mature: 26326

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIILDTETTGLNAATGDRVIEIGCVEMVNRRLTGRNLHFYINPEREIDAGAMAVHGIT
CCEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCH
NEFVADKPKFAEIVNEIRDYVQGAEAIIHNAAFDLGFLDMEFQRLGLPAFREHLSGHIDT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
LREARQMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAELLAEVYLAMTRGQNTLVIDML
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ESGEGASAEAVAVDLSALQLPVLLATEAEAEAHAGVLKEIDKASGGKTVWTREPVESAQP
CCCCCCCCHHEEEEHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
AA
CC
>Mature Secondary Structure
MRQIILDTETTGLNAATGDRVIEIGCVEMVNRRLTGRNLHFYINPEREIDAGAMAVHGIT
CCEEEEECCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEECCCH
NEFVADKPKFAEIVNEIRDYVQGAEAIIHNAAFDLGFLDMEFQRLGLPAFREHLSGHIDT
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHH
LREARQMFPGKRNSLDALCDRLGVSNAHRTLHGALLDAELLAEVYLAMTRGQNTLVIDML
HHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
ESGEGASAEAVAVDLSALQLPVLLATEAEAEAHAGVLKEIDKASGGKTVWTREPVESAQP
CCCCCCCCHHEEEEHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCCC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]