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The map label for this gene is cutS [H]

Identifier: 187929133

GI number: 187929133

Start: 2166588

End: 2167163

Strand: Direct

Name: cutS [H]

Synonym: Rpic_2054

Alternate gene names: 187929133

Gene position: 2166588-2167163 (Clockwise)

Preceding gene: 187929132

Following gene: 187929134

Centisome position: 54.95

GC content: 65.1

Gene sequence:

>576_bases
ATGAGTAAAACCAAGAAAGGCGGCGCGCCTTCCAGTGCGCTTTCTGTGATGCGGCGACAGGAGCACCACCGCATCGCCCT
GACATTGAACGGCAGCGCGCGTACCGGCCTGTGTGCGCCGCGCGAGTTGCTATCCGACTTCCTGCGCCATGAGCTCGGCG
CCACCGGCACCCACGTTGGTTGTGAGCATGGCGTATGCGGTGCGTGCACGGTGCGTGTGGACGGCGTGGCTTCCCGCTCC
TGCCTGATGCTGGCCGTGCAGGCGGACGGTCGTGCAGTCGACACCGTCGAAGGCCTCGCCACGCACGAAGGTTTGAGCGA
TTTACAGGAGGCTTTCCGCCGCCATCACGCCCTGCAATGCGGCTTCTGCACGGCAGGCATCCTGATGTCGTGCGCAGACT
ATCTGGAGCGCGTGCCCGAGCCGACTGAGGCGCAAGTGCGCGAGATGTTGTCCGGTCATCTGTGCCGCTGTACCGGCTAC
ACACCGATCGTTGCCGCCGTCCTTGACGTCGCCGCCAGCCGCGCAGGGGCACGCCCGATTTCAGCGCCGGTTTCCGAGGA
GACCAGCAATGCTTGA

Upstream 100 bases:

>100_bases
TCAGTTGGAAATTGGGCGCGCAAGACGACGCCCATGTCAGCGCGCAGTACCGCCGCCACCTCGTGCGGCAACTGGGCATG
CGCGCAATCGAGGAGGCAAG

Downstream 100 bases:

>100_bases
TCTCGGCCGCACATTCCTGCAGAGCGTGGAGCGCAGCCCCCACGCTCTCGCCATAGTCGACGGGGACCTGAAACTATCCT
ATGCGCAATGGCTAACGCGC

Product: (2Fe-2S)-binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSKTKKGGAPSSALSVMRRQEHHRIALTLNGSARTGLCAPRELLSDFLRHELGATGTHVGCEHGVCGACTVRVDGVASRS
CLMLAVQADGRAVDTVEGLATHEGLSDLQEAFRRHHALQCGFCTAGILMSCADYLERVPEPTEAQVREMLSGHLCRCTGY
TPIVAAVLDVAASRAGARPISAPVSEETSNA

Sequences:

>Translated_191_residues
MSKTKKGGAPSSALSVMRRQEHHRIALTLNGSARTGLCAPRELLSDFLRHELGATGTHVGCEHGVCGACTVRVDGVASRS
CLMLAVQADGRAVDTVEGLATHEGLSDLQEAFRRHHALQCGFCTAGILMSCADYLERVPEPTEAQVREMLSGHLCRCTGY
TPIVAAVLDVAASRAGARPISAPVSEETSNA
>Mature_190_residues
SKTKKGGAPSSALSVMRRQEHHRIALTLNGSARTGLCAPRELLSDFLRHELGATGTHVGCEHGVCGACTVRVDGVASRSC
LMLAVQADGRAVDTVEGLATHEGLSDLQEAFRRHHALQCGFCTAGILMSCADYLERVPEPTEAQVREMLSGHLCRCTGYT
PIVAAVLDVAASRAGARPISAPVSEETSNA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=98, Percent_Identity=43.8775510204082, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI91823271, Length=136, Percent_Identity=40.4411764705882, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786480, Length=162, Percent_Identity=38.2716049382716, Blast_Score=112, Evalue=1e-26,
Organism=Escherichia coli, GI1789232, Length=160, Percent_Identity=43.125, Blast_Score=112, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=152, Percent_Identity=37.5, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI32566215, Length=148, Percent_Identity=37.8378378378378, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=138, Percent_Identity=39.1304347826087, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17737937, Length=152, Percent_Identity=37.5, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24647193, Length=160, Percent_Identity=33.125, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24647199, Length=146, Percent_Identity=34.2465753424658, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647197, Length=164, Percent_Identity=31.7073170731707, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647195, Length=164, Percent_Identity=31.7073170731707, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24647201, Length=158, Percent_Identity=32.9113924050633, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 20138; Mature: 20007

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
7.9 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTKKGGAPSSALSVMRRQEHHRIALTLNGSARTGLCAPRELLSDFLRHELGATGTHVG
CCCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
CEHGVCGACTVRVDGVASRSCLMLAVQADGRAVDTVEGLATHEGLSDLQEAFRRHHALQC
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GFCTAGILMSCADYLERVPEPTEAQVREMLSGHLCRCTGYTPIVAAVLDVAASRAGARPI
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCC
SAPVSEETSNA
CCCCCCCCCCC
>Mature Secondary Structure 
SKTKKGGAPSSALSVMRRQEHHRIALTLNGSARTGLCAPRELLSDFLRHELGATGTHVG
CCCCCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
CEHGVCGACTVRVDGVASRSCLMLAVQADGRAVDTVEGLATHEGLSDLQEAFRRHHALQC
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCC
GFCTAGILMSCADYLERVPEPTEAQVREMLSGHLCRCTGYTPIVAAVLDVAASRAGARPI
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCCCC
SAPVSEETSNA
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]