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The map label for this gene is glmM

Identifier: 187929106

GI number: 187929106

Start: 2133448

End: 2134791

Strand: Reverse

Name: glmM

Synonym: Rpic_2027

Alternate gene names: 187929106

Gene position: 2134791-2133448 (Counterclockwise)

Preceding gene: 187929107

Following gene: 187929105

Centisome position: 54.15

GC content: 63.02

Gene sequence:

>1344_bases
ATGTCCAGGAAGTATTTCGGCACCGACGGCATTCGTGGGCGTGTCGGTGAAAGCCCGATCACGCCGGATTTTGTGTTGCG
CCTTGGTTATGCAGCCGGCCGTGTGTTGGCCCATGGTGGGGAAGCGCATGGTCACGGCCGTCCCACCGTGCTGATCGGCA
AGGACACGCGCCTGTCGGGCTACATGCTGGAAGCCGCGTTGGAAGCAGGCTTCACAGCAGCCGGCGTGGACGTGTTGATG
AGCGGGCCGCTGCCAACGCCTGGCGTGGCGTATCTCACGCGTGCGCTGCGGTTGTCGGCGGGTGTGGTGATTTCCGCTTC
ACATAACCCGTATTACGACAACGGTATCAAGTTCTTCTCGGCCACCGGCGACAAGCTGCCGGATGAAACCGAGCTGCAGA
TCGAAGCCGAACTGGAAAAGCCGATGGCGTACGCGGCCTCTGATGCGCTGGGCCGTGCCCGTCGTATCGAGGATGCCGCT
GGACGCTACATCGAATTCTGCAAGAGCACATTCCCGAGCGACCTGAACCTGTTCGGTATGAAGGTCGTGCTGGACAGCGC
GCATGGCGCGGCCTATCACATTGCACCGCACGTCTTCCACGAACTGGGTGCGGACGTGGTATCGATCGGCAACCAGCCGA
ATGGCCGCAACATCAACGACGGCTATGGCGCGACGGCGCCGGGTAAGTTGGTTGAGGCTACACGCGAGCATGGGGCTGAC
ATTGGCCTGGCCTTTGATGGCGATGCCGACCGCCTGCAGGTGGTGGACCGCAATGGGCGCCTCTACAACGGCGACGAGCT
GCTCTACGTGATGGTGCAGGCGCGCCGTGCGGCGGGCCAGACGGTGCCGGGCGCGGTCGGTACGCTCATGACCAATCTTG
CCGTGGAACTCGCACTCAAGGCGCAGGGGGTCGAGTTCGTGCGCGCCAAGGTGGGCGATCGCTATGTGCTGGAAGAACTG
AAGAAGAATGGTTGGCTGCTCGGCGGCGAAGGTTCGGGCCACTTGCTCTGCCTGGACAAGCACAGCACGGGCGACGGCAT
CATTTCGGCGCTGCAGGTGCTTGCAGCATTGCGTCGCAGCGGCCAGACGCTGGACGAGATGCTCGACGGCGTGCGCCTGT
TCCCGCAAAAGCTTATCAACGTGCGGGTCGAAAAGGGTTTCGACTGGAAATCGCACGCGGGCTTGCAGGCGGCTCTCAAG
ACGAGCGAGGCCGAGTTGGATGGCAAGGGGCGTGTGCTGATTCGTCCGTCGGGTACGGAGCCGGTCGTGCGCGTCATGGT
GGAAGCGCAGGACGCTGAGCTGGCCAACCAACATGCGGAGCGTCTTGCCGCGACGTTGCAGTAA

Upstream 100 bases:

>100_bases
AAGCCTCACGCGGCTGGGGGTCAAGCGAACAGAGGATTGCCCGGCGATGGCCAGCGCCTTACAAACAAAGAAAGAAACAT
TTCTCCAGGAGAGACTCCCA

Downstream 100 bases:

>100_bases
GTTGTTGCCAGATCAAGCAAACATGTCGAAAAGCGGCCTCCGGGCCGCTTTTTTTATGCGTGGGGGTCGACTTTCCTGCC
GTGCAGGCCGGCTATGAGAA

Product: phosphoglucosamine mutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGGEAHGHGRPTVLIGKDTRLSGYMLEAALEAGFTAAGVDVLM
SGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFSATGDKLPDETELQIEAELEKPMAYAASDALGRARRIEDAA
GRYIEFCKSTFPSDLNLFGMKVVLDSAHGAAYHIAPHVFHELGADVVSIGNQPNGRNINDGYGATAPGKLVEATREHGAD
IGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQTVPGAVGTLMTNLAVELALKAQGVEFVRAKVGDRYVLEEL
KKNGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRSGQTLDEMLDGVRLFPQKLINVRVEKGFDWKSHAGLQAALK
TSEAELDGKGRVLIRPSGTEPVVRVMVEAQDAELANQHAERLAATLQ

Sequences:

>Translated_447_residues
MSRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGGEAHGHGRPTVLIGKDTRLSGYMLEAALEAGFTAAGVDVLM
SGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFSATGDKLPDETELQIEAELEKPMAYAASDALGRARRIEDAA
GRYIEFCKSTFPSDLNLFGMKVVLDSAHGAAYHIAPHVFHELGADVVSIGNQPNGRNINDGYGATAPGKLVEATREHGAD
IGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQTVPGAVGTLMTNLAVELALKAQGVEFVRAKVGDRYVLEEL
KKNGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRSGQTLDEMLDGVRLFPQKLINVRVEKGFDWKSHAGLQAALK
TSEAELDGKGRVLIRPSGTEPVVRVMVEAQDAELANQHAERLAATLQ
>Mature_446_residues
SRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGGEAHGHGRPTVLIGKDTRLSGYMLEAALEAGFTAAGVDVLMS
GPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFSATGDKLPDETELQIEAELEKPMAYAASDALGRARRIEDAAG
RYIEFCKSTFPSDLNLFGMKVVLDSAHGAAYHIAPHVFHELGADVVSIGNQPNGRNINDGYGATAPGKLVEATREHGADI
GLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQTVPGAVGTLMTNLAVELALKAQGVEFVRAKVGDRYVLEELK
KNGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRSGQTLDEMLDGVRLFPQKLINVRVEKGFDWKSHAGLQAALKT
SEAELDGKGRVLIRPSGTEPVVRVMVEAQDAELANQHAERLAATLQ

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Escherichia coli, GI1789566, Length=447, Percent_Identity=55.4809843400447, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1788361, Length=459, Percent_Identity=29.8474945533769, Blast_Score=119, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI71993870, Length=312, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71993878, Length=305, Percent_Identity=26.8852459016393, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_RALPJ (B2UGP7)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001899593.1
- ProteinModelPortal:   B2UGP7
- SMR:   B2UGP7
- GeneID:   6287751
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_2027
- HOGENOM:   HBG644964
- OMA:   AHAVGRV
- ProtClustDB:   PRK10887
- HAMAP:   MF_01554_B
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- InterPro:   IPR006352
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509
- TIGRFAMs:   TIGR01455

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 47788; Mature: 47657

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 107-107

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGGEAHGHGRPTVLIGKDTRLSG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCCH
YMLEAALEAGFTAAGVDVLMSGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFS
HHHHHHHHCCCCHHCCHHEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEE
ATGDKLPDETELQIEAELEKPMAYAASDALGRARRIEDAAGRYIEFCKSTFPSDLNLFGM
CCCCCCCCCCCEEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
KVVLDSAHGAAYHIAPHVFHELGADVVSIGNQPNGRNINDGYGATAPGKLVEATREHGAD
EEEEECCCCCEEEHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCE
IGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQTVPGAVGTLMTNLAVELALK
EEEEECCCCCEEEEEECCCCEECCCCEEEHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AQGVEFVRAKVGDRYVLEELKKNGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRS
HCCHHHHHHHCCCHHHHHHHHHCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
GQTLDEMLDGVRLFPQKLINVRVEKGFDWKSHAGLQAALKTSEAELDGKGRVLIRPSGTE
CCHHHHHHHHHHHHHHHHHHEEHCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEECCCCC
PVVRVMVEAQDAELANQHAERLAATLQ
CEEEEEEECHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRKYFGTDGIRGRVGESPITPDFVLRLGYAAGRVLAHGGEAHGHGRPTVLIGKDTRLSG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCCH
YMLEAALEAGFTAAGVDVLMSGPLPTPGVAYLTRALRLSAGVVISASHNPYYDNGIKFFS
HHHHHHHHCCCCHHCCHHEEECCCCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEE
ATGDKLPDETELQIEAELEKPMAYAASDALGRARRIEDAAGRYIEFCKSTFPSDLNLFGM
CCCCCCCCCCCEEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
KVVLDSAHGAAYHIAPHVFHELGADVVSIGNQPNGRNINDGYGATAPGKLVEATREHGAD
EEEEECCCCCEEEHHHHHHHHHCCHHEECCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCE
IGLAFDGDADRLQVVDRNGRLYNGDELLYVMVQARRAAGQTVPGAVGTLMTNLAVELALK
EEEEECCCCCEEEEEECCCCEECCCCEEEHEEHHHHHCCCCCCHHHHHHHHHHHHHHHHH
AQGVEFVRAKVGDRYVLEELKKNGWLLGGEGSGHLLCLDKHSTGDGIISALQVLAALRRS
HCCHHHHHHHCCCHHHHHHHHHCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHC
GQTLDEMLDGVRLFPQKLINVRVEKGFDWKSHAGLQAALKTSEAELDGKGRVLIRPSGTE
CCHHHHHHHHHHHHHHHHHHEEHCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEEECCCCC
PVVRVMVEAQDAELANQHAERLAATLQ
CEEEEEEECHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA