| Definition | Ralstonia pickettii 12J chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010682 |
| Length | 3,942,557 |
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The map label for this gene is relA [H]
Identifier: 187929058
GI number: 187929058
Start: 2087482
End: 2089707
Strand: Reverse
Name: relA [H]
Synonym: Rpic_1978
Alternate gene names: 187929058
Gene position: 2089707-2087482 (Counterclockwise)
Preceding gene: 187929059
Following gene: 187929057
Centisome position: 53.0
GC content: 64.11
Gene sequence:
>2226_bases ATGGAGAACAAGACCGAACGGCCGGCCGAGTTGCCCGGATCGACGGCAGAGCAGGTCGCTCGGGCGATCGAATACCTCGC GGCCAATGCCGCAGACAGCGTCACGCTGACCGGCGAGCCGCTGGAGTCGCATGCGCGCGGCACGATCGCCATCCTTGAAG GGTTGCGTGTCGACACGCCGTCGTTGCAGGCGGCCGCGCTGTTTCTGTTGCCCACGCTGGCAATGGACAGCGAAAAGGCG CTCGAGCCTGCATTCGGTGCCGAGGTCGTCAAGCTCGTGCACGACGTGCGGCAACTGCTGCGCATTGGCGCGATTGCGGG CCTCGTCAGCCCGACCGATGCCAGCATTACGCGCAAGAACGAAGCCGAAGCACGCCGCGCGCAAGTCGAGGCGTTGCGCA AGATGTTGCTCGCGTTCGCGCAAGACATTCGCGTGGTGATGATCCGCCTGGCGTCGCGGTTGCAGTCGCTTCGCTGGCTG GCCCAGACGAAGCGGTCGGCGCCGGAAGGCATGGCGCGCGAGACGCTGGATATCTACGCGCCGCTCGCAAACCGCCTGGG CATCTGGCAGCTGAAGTGGGAGCTTGAAGACCTCGGCTTCCGCTTTGAGGATCCCGATACCTATAAGCGCATCGCGCGCC TGCTGGACGAAAAGCGCATCGAGCGCGAGAAGTTCATCGGCCAGGCCATCGAGCAACTCCAAAAGACATTGCACGATGCC GGCATTCAGGCTGAGGTCAGCGGTCGGCCCAAGCACATCTACAGCATCTGGAAGAAGATGCGAGGCAAGGAACTGGACTT TGCCGATCTGTACGACGTGCGCGCCTTCCGTGTCATCGTCGACGACATCAAGGATTGCTACACGGTGCTCGGTTTCGTGC ACCACATGTGGCAGCCGATCCCGAAAGAGTTCGACGACTACATCTCACGCCCAAAGGCCAACGGCTACATGTCGCTGCAC ACGGTGGTGATCGGCGACGACGGCCGTGCGCTCGAGGTGCAGATTCGCACGCGCGAGATGCACCACTTTGCCGAGTACGG CGTGGCTGCGCACTGGCGCTACAAGGAGGCGGGCAACAAGGGCTACGCCGGCCAGTTCTCTGCCAGCGAGCGCTACGACG AGAAGATCGCGTGGCTGCGCCAGTTGCTCGCCTGGAAAGATGACGCCGAGCACACCGTCGCGCACGAGGATTCGCCGTGG GAGCAGCTCAAGCACACCGAGCTGGATGACCACATTTACGTGCTGACGCCGCAGGCGCGCGTGATCGCGTTGCCGCAAGG TGCGACGCCCGTCGATTTTGCGTATTACCTGCATAGCGATCTCGGCCACCGCTGCCGCGGCGCGCGCGTCGACGGCACGA TGGTGCCGCTGAACACGCCGCTCAAGAACGGCCAGACCGTCGAGATTGTTACCGTCAAGCACGGCGGGCCGTCACGTGAT TGGCTGAACACCGAGCTGCACTATCTTGTCAGCCCGCGCGCCCGCACGAAAGTGCGCGCGTGGTTCAACGCGATGGAACT GGAAGAGACGCTCGCGCAGGGCCGGGCGCTTATCGACAAGACGCTGCAGCGTGAGGGCAAGACCGCCGTCAACCTGGAAG AACTGGCCGCCAAGCTCGGCTACAAGACGTCGGACGATCTCTATGCCGTGGTCGCCAAGGACGAACTGAGCCTGCGCCGC ATCGAGGCCGTTTTGCGCTCGGATGGGGCGCCGCCGCCCGCGCCCGTCGACGACGAAGCGGCCATCACCAAGAAGAGCCG CGCCACCAGCGTGGCTCGTGGCGCCAAGAGCGGCGTGCTCGTGGTGGGCGTCGATTCGCTCCTCACGCAGATGTCGCGTT GCTGCAAGCCGGCACCGCCGGACCCCATCGTTGGTTTTGTCACGCGTGGGCGCGGCGTATCGATCCACCGTCAGAGCTGC GCGACCTTTCAGCAACTGGCTGCCCGGGCGCCCGGCCGTGTAATCCAGACGGAATGGGGCCAGCGCAGCGATTCGGTCTA TCCGATCGACATCCAGGTCGAGGCGCTGGACCGGCAGGGATTGTTGCGTGACATCTCGGAAATCCTCTCGCGCGAGAAGA TCAACGTGACCGGCGTGCGCACGCTGTCGAGCAAAGGCGTCGCAAAAATGCAGTTCACCGCGGAGGTGGCAGAGGCGACA CAGCTGCAGCGCGCGCTGACTTTGATCGAAGAGGTGCAGGGGGTGTTGACAGCTCGAAGGAAGTGA
Upstream 100 bases:
>100_bases CCGCGCTGGCCAATCCGAAGTACCGTATCGAAATCGTCGTGACGGCCGCGCAGAAAAGCTGAGCCCGTCGCGTCACAGCA GGACGCAAGCAGGACGCATC
Downstream 100 bases:
>100_bases CGGTATAGTTTCGTTCTTCGGCAGGCTCGTAGCTCAGCTGGTTAGAGCACCACCTTGACATGGTGGGGGTCGTTGGTTCG AGTCCAATCGAGCCTACCAA
Product: (p)ppGpp synthetase I SpoT/RelA
Products: NA
Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]
Number of amino acids: Translated: 741; Mature: 741
Protein sequence:
>741_residues MENKTERPAELPGSTAEQVARAIEYLAANAADSVTLTGEPLESHARGTIAILEGLRVDTPSLQAAALFLLPTLAMDSEKA LEPAFGAEVVKLVHDVRQLLRIGAIAGLVSPTDASITRKNEAEARRAQVEALRKMLLAFAQDIRVVMIRLASRLQSLRWL AQTKRSAPEGMARETLDIYAPLANRLGIWQLKWELEDLGFRFEDPDTYKRIARLLDEKRIEREKFIGQAIEQLQKTLHDA GIQAEVSGRPKHIYSIWKKMRGKELDFADLYDVRAFRVIVDDIKDCYTVLGFVHHMWQPIPKEFDDYISRPKANGYMSLH TVVIGDDGRALEVQIRTREMHHFAEYGVAAHWRYKEAGNKGYAGQFSASERYDEKIAWLRQLLAWKDDAEHTVAHEDSPW EQLKHTELDDHIYVLTPQARVIALPQGATPVDFAYYLHSDLGHRCRGARVDGTMVPLNTPLKNGQTVEIVTVKHGGPSRD WLNTELHYLVSPRARTKVRAWFNAMELEETLAQGRALIDKTLQREGKTAVNLEELAAKLGYKTSDDLYAVVAKDELSLRR IEAVLRSDGAPPPAPVDDEAAITKKSRATSVARGAKSGVLVVGVDSLLTQMSRCCKPAPPDPIVGFVTRGRGVSIHRQSC ATFQQLAARAPGRVIQTEWGQRSDSVYPIDIQVEALDRQGLLRDISEILSREKINVTGVRTLSSKGVAKMQFTAEVAEAT QLQRALTLIEEVQGVLTARRK
Sequences:
>Translated_741_residues MENKTERPAELPGSTAEQVARAIEYLAANAADSVTLTGEPLESHARGTIAILEGLRVDTPSLQAAALFLLPTLAMDSEKA LEPAFGAEVVKLVHDVRQLLRIGAIAGLVSPTDASITRKNEAEARRAQVEALRKMLLAFAQDIRVVMIRLASRLQSLRWL AQTKRSAPEGMARETLDIYAPLANRLGIWQLKWELEDLGFRFEDPDTYKRIARLLDEKRIEREKFIGQAIEQLQKTLHDA GIQAEVSGRPKHIYSIWKKMRGKELDFADLYDVRAFRVIVDDIKDCYTVLGFVHHMWQPIPKEFDDYISRPKANGYMSLH TVVIGDDGRALEVQIRTREMHHFAEYGVAAHWRYKEAGNKGYAGQFSASERYDEKIAWLRQLLAWKDDAEHTVAHEDSPW EQLKHTELDDHIYVLTPQARVIALPQGATPVDFAYYLHSDLGHRCRGARVDGTMVPLNTPLKNGQTVEIVTVKHGGPSRD WLNTELHYLVSPRARTKVRAWFNAMELEETLAQGRALIDKTLQREGKTAVNLEELAAKLGYKTSDDLYAVVAKDELSLRR IEAVLRSDGAPPPAPVDDEAAITKKSRATSVARGAKSGVLVVGVDSLLTQMSRCCKPAPPDPIVGFVTRGRGVSIHRQSC ATFQQLAARAPGRVIQTEWGQRSDSVYPIDIQVEALDRQGLLRDISEILSREKINVTGVRTLSSKGVAKMQFTAEVAEAT QLQRALTLIEEVQGVLTARRK >Mature_741_residues MENKTERPAELPGSTAEQVARAIEYLAANAADSVTLTGEPLESHARGTIAILEGLRVDTPSLQAAALFLLPTLAMDSEKA LEPAFGAEVVKLVHDVRQLLRIGAIAGLVSPTDASITRKNEAEARRAQVEALRKMLLAFAQDIRVVMIRLASRLQSLRWL AQTKRSAPEGMARETLDIYAPLANRLGIWQLKWELEDLGFRFEDPDTYKRIARLLDEKRIEREKFIGQAIEQLQKTLHDA GIQAEVSGRPKHIYSIWKKMRGKELDFADLYDVRAFRVIVDDIKDCYTVLGFVHHMWQPIPKEFDDYISRPKANGYMSLH TVVIGDDGRALEVQIRTREMHHFAEYGVAAHWRYKEAGNKGYAGQFSASERYDEKIAWLRQLLAWKDDAEHTVAHEDSPW EQLKHTELDDHIYVLTPQARVIALPQGATPVDFAYYLHSDLGHRCRGARVDGTMVPLNTPLKNGQTVEIVTVKHGGPSRD WLNTELHYLVSPRARTKVRAWFNAMELEETLAQGRALIDKTLQREGKTAVNLEELAAKLGYKTSDDLYAVVAKDELSLRR IEAVLRSDGAPPPAPVDDEAAITKKSRATSVARGAKSGVLVVGVDSLLTQMSRCCKPAPPDPIVGFVTRGRGVSIHRQSC ATFQQLAARAPGRVIQTEWGQRSDSVYPIDIQVEALDRQGLLRDISEILSREKINVTGVRTLSSKGVAKMQFTAEVAEAT QLQRALTLIEEVQGVLTARRK
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ACT domain [H]
Homologues:
Organism=Escherichia coli, GI1789147, Length=702, Percent_Identity=41.1680911680912, Blast_Score=547, Evalue=1e-156, Organism=Escherichia coli, GI1790082, Length=675, Percent_Identity=34.8148148148148, Blast_Score=406, Evalue=1e-114,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =2.7.6.5 [H]
Molecular weight: Translated: 82836; Mature: 82836
Theoretical pI: Translated: 8.00; Mature: 8.00
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MENKTERPAELPGSTAEQVARAIEYLAANAADSVTLTGEPLESHARGTIAILEGLRVDTP CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHCCCEEEEHHCCCCCCC SLQAAALFLLPTLAMDSEKALEPAFGAEVVKLVHDVRQLLRIGAIAGLVSPTDASITRKN CHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC EAEARRAQVEALRKMLLAFAQDIRVVMIRLASRLQSLRWLAQTKRSAPEGMARETLDIYA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH PLANRLGIWQLKWELEDLGFRFEDPDTYKRIARLLDEKRIEREKFIGQAIEQLQKTLHDA HHHHCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC GIQAEVSGRPKHIYSIWKKMRGKELDFADLYDVRAFRVIVDDIKDCYTVLGFVHHMWQPI CCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC PKEFDDYISRPKANGYMSLHTVVIGDDGRALEVQIRTREMHHFAEYGVAAHWRYKEAGNK CHHHHHHHCCCCCCCEEEEEEEEECCCCCEEEEEEEHHHHHHHHHCCCCEEEEEHHCCCC GYAGQFSASERYDEKIAWLRQLLAWKDDAEHTVAHEDSPWEQLKHTELDDHIYVLTPQAR CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCE VIALPQGATPVDFAYYLHSDLGHRCRGARVDGTMVPLNTPLKNGQTVEIVTVKHGGPSRD EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCCCC WLNTELHYLVSPRARTKVRAWFNAMELEETLAQGRALIDKTLQREGKTAVNLEELAAKLG CCCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC YKTSDDLYAVVAKDELSLRRIEAVLRSDGAPPPAPVDDEAAITKKSRATSVARGAKSGVL CCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEE VVGVDSLLTQMSRCCKPAPPDPIVGFVTRGRGVSIHRQSCATFQQLAARAPGRVIQTEWG EEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEECCCC QRSDSVYPIDIQVEALDRQGLLRDISEILSREKINVTGVRTLSSKGVAKMQFTAEVAEAT CCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHH QLQRALTLIEEVQGVLTARRK HHHHHHHHHHHHHHHHHHCCC >Mature Secondary Structure MENKTERPAELPGSTAEQVARAIEYLAANAADSVTLTGEPLESHARGTIAILEGLRVDTP CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCHHHHCCCEEEEHHCCCCCCC SLQAAALFLLPTLAMDSEKALEPAFGAEVVKLVHDVRQLLRIGAIAGLVSPTDASITRKN CHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC EAEARRAQVEALRKMLLAFAQDIRVVMIRLASRLQSLRWLAQTKRSAPEGMARETLDIYA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH PLANRLGIWQLKWELEDLGFRFEDPDTYKRIARLLDEKRIEREKFIGQAIEQLQKTLHDA HHHHCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC GIQAEVSGRPKHIYSIWKKMRGKELDFADLYDVRAFRVIVDDIKDCYTVLGFVHHMWQPI CCEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC PKEFDDYISRPKANGYMSLHTVVIGDDGRALEVQIRTREMHHFAEYGVAAHWRYKEAGNK CHHHHHHHCCCCCCCEEEEEEEEECCCCCEEEEEEEHHHHHHHHHCCCCEEEEEHHCCCC GYAGQFSASERYDEKIAWLRQLLAWKDDAEHTVAHEDSPWEQLKHTELDDHIYVLTPQAR CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCE VIALPQGATPVDFAYYLHSDLGHRCRGARVDGTMVPLNTPLKNGQTVEIVTVKHGGPSRD EEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEEECCCCCCC WLNTELHYLVSPRARTKVRAWFNAMELEETLAQGRALIDKTLQREGKTAVNLEELAAKLG CCCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC YKTSDDLYAVVAKDELSLRRIEAVLRSDGAPPPAPVDDEAAITKKSRATSVARGAKSGVL CCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEE VVGVDSLLTQMSRCCKPAPPDPIVGFVTRGRGVSIHRQSCATFQQLAARAPGRVIQTEWG EEEHHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCCCEEECCCC QRSDSVYPIDIQVEALDRQGLLRDISEILSREKINVTGVRTLSSKGVAKMQFTAEVAEAT CCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEHHHHHHHHHH QLQRALTLIEEVQGVLTARRK HHHHHHHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 7928955 [H]