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The map label for this gene is yhdG [H]

Identifier: 187929042

GI number: 187929042

Start: 2072020

End: 2073450

Strand: Reverse

Name: yhdG [H]

Synonym: Rpic_1962

Alternate gene names: 187929042

Gene position: 2073450-2072020 (Counterclockwise)

Preceding gene: 187929043

Following gene: 187929041

Centisome position: 52.59

GC content: 62.75

Gene sequence:

>1431_bases
ATGAGTTTGTTTCGTACCAAAAACGTGGATCACATGATCCGCACGGGCCACAGCGACACCGGCCTGAAGAAAGTCCTCGG
GCCCCTCGACCTGACCTTCCTGGGTGTCGGCGCCATCATCGGAACCGGCATCTTCGTGCTGACCGGCACCGGCGCGCTGA
CGGCAGGGCCGGCGCTCACGCTGTCCTTCATCATCGCAGCGCTTGCATGCGGGTTTGCCGCGCTGTGCTACGCCGAATTC
GCCTCGACCATTCCCGTGTCGGGCTCCATCTATACGTATGCCTACGCCACGATGGGCGAGCTGGTCGCCTGGATCATCGG
CTGGGATCTGATGCTCGAATATGGCTTGGCCACATCTGCTGTTTCGGTGGGTTGGTCCGGCTATTTCCAGTCGCTGCTGT
CGGGCTTCGGCCTTCATCTGCCGGTGGCGCTCACTGCCGCTCCGGGCGCAATCCCGGGCGTGCAGACACTGTTCAACCTT
CCGGCGCTGGTGATCATGCTGCTGATCACGACGCTGCTGTCGTTTGGCATTCGCGAATCGGCGCGTGCCAACAACATCAT
GGTGGCGATCAAGGTAACGGTGGTGGTGCTGTTCATCGTCGTGGGTGTGCGCCATGTGCAGCCGGCCAACTGGCAGCCGT
TCATGCCGTTCGGCATGGAAGGCGTGTTTGGCGCGGCGGCCATCGTGTTCTTCGCTTTCATCGGCTTCGATGCGGTGACG
TCCGCGGCCGAAGAGGTGCGCAATCCCAAGCGCGACTTGCCGATCGGCATCATCGGTTCACTGGCGGTCTGCACGATTCT
CTATGTACTGGTGGCCGCCATCATGACGGGCATCGTGCCGTTCGCGAAGTTTGCAGGCGTGGATCACCCCGTGTCGCTGG
CGCTGCAAGTGGCCGGCGAAAGCTGGGTGGCAGGCTTTGTTGATCTGGGCGCCATCATTGGCATGACCACGGTGATCCTG
GTGATGGCGTATGGCCAGACTCGCATCATCTTCGCGATGTCGCGCGACGGTCTGCTGCCCAAGCGCCTGTCGCACATTCA
TCCGCGCTACGCGACGCCGTTCCTGAACACCTGGGTGGTCGGCATCGTCTTCGCGGTGATCGCCGCATTCGTGCCGCTGA
ACGTGTTGGCTGAGCTGATCAACATCGGAACGCTGGCAGCGTTCTCGCTGATTGCCGTTGCCGTGCTGGTGCTGCGCCGT
ACCCGTCCAGACCTTCATCGCGGCTTCCGTTGCCCAGGCGTGCCGGTGGTGCCGCTGCTGGCCATCGGCATGTGCCTGTT
CCTGATGAGCCACCTGCAGGCCGTCACCTGGATCGCCTTTTTGGTGTGGGTCGCGATCGGCTTGCTGGTGTACTTCGGCT
ACGCGCGCCGCCGCTCGCTGCTGCACACGTCGGAGCATGGCGCTGCACCCGTTTCCGAAACGGTGCACTGA

Upstream 100 bases:

>100_bases
GTAAAATGCTCGCTTTTTTGCATAATCCGCCGCCGCGCATCAAACGTGCGCGACAGTGCATGCCGTCACATTCGGCCGCA
CGCAGACAGGAGACGCAGTA

Downstream 100 bases:

>100_bases
TCAGGAAGGCGCGTCCATTCCCTGACGACATGGTTGCCACGCGGCTGAACACTGTCGTTCAGGGCGCCGGCTGAGCGGTT
TTTCCCTCAGTCGGCGCGCA

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MSLFRTKNVDHMIRTGHSDTGLKKVLGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALTLSFIIAALACGFAALCYAEF
ASTIPVSGSIYTYAYATMGELVAWIIGWDLMLEYGLATSAVSVGWSGYFQSLLSGFGLHLPVALTAAPGAIPGVQTLFNL
PALVIMLLITTLLSFGIRESARANNIMVAIKVTVVVLFIVVGVRHVQPANWQPFMPFGMEGVFGAAAIVFFAFIGFDAVT
SAAEEVRNPKRDLPIGIIGSLAVCTILYVLVAAIMTGIVPFAKFAGVDHPVSLALQVAGESWVAGFVDLGAIIGMTTVIL
VMAYGQTRIIFAMSRDGLLPKRLSHIHPRYATPFLNTWVVGIVFAVIAAFVPLNVLAELINIGTLAAFSLIAVAVLVLRR
TRPDLHRGFRCPGVPVVPLLAIGMCLFLMSHLQAVTWIAFLVWVAIGLLVYFGYARRRSLLHTSEHGAAPVSETVH

Sequences:

>Translated_476_residues
MSLFRTKNVDHMIRTGHSDTGLKKVLGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALTLSFIIAALACGFAALCYAEF
ASTIPVSGSIYTYAYATMGELVAWIIGWDLMLEYGLATSAVSVGWSGYFQSLLSGFGLHLPVALTAAPGAIPGVQTLFNL
PALVIMLLITTLLSFGIRESARANNIMVAIKVTVVVLFIVVGVRHVQPANWQPFMPFGMEGVFGAAAIVFFAFIGFDAVT
SAAEEVRNPKRDLPIGIIGSLAVCTILYVLVAAIMTGIVPFAKFAGVDHPVSLALQVAGESWVAGFVDLGAIIGMTTVIL
VMAYGQTRIIFAMSRDGLLPKRLSHIHPRYATPFLNTWVVGIVFAVIAAFVPLNVLAELINIGTLAAFSLIAVAVLVLRR
TRPDLHRGFRCPGVPVVPLLAIGMCLFLMSHLQAVTWIAFLVWVAIGLLVYFGYARRRSLLHTSEHGAAPVSETVH
>Mature_475_residues
SLFRTKNVDHMIRTGHSDTGLKKVLGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALTLSFIIAALACGFAALCYAEFA
STIPVSGSIYTYAYATMGELVAWIIGWDLMLEYGLATSAVSVGWSGYFQSLLSGFGLHLPVALTAAPGAIPGVQTLFNLP
ALVIMLLITTLLSFGIRESARANNIMVAIKVTVVVLFIVVGVRHVQPANWQPFMPFGMEGVFGAAAIVFFAFIGFDAVTS
AAEEVRNPKRDLPIGIIGSLAVCTILYVLVAAIMTGIVPFAKFAGVDHPVSLALQVAGESWVAGFVDLGAIIGMTTVILV
MAYGQTRIIFAMSRDGLLPKRLSHIHPRYATPFLNTWVVGIVFAVIAAFVPLNVLAELINIGTLAAFSLIAVAVLVLRRT
RPDLHRGFRCPGVPVVPLLAIGMCLFLMSHLQAVTWIAFLVWVAIGLLVYFGYARRRSLLHTSEHGAAPVSETVH

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI258614005, Length=412, Percent_Identity=37.1359223300971, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI258614003, Length=412, Percent_Identity=37.1359223300971, Blast_Score=239, Evalue=5e-63,
Organism=Homo sapiens, GI258645169, Length=412, Percent_Identity=36.8932038834951, Blast_Score=235, Evalue=7e-62,
Organism=Homo sapiens, GI4507047, Length=437, Percent_Identity=36.8421052631579, Blast_Score=235, Evalue=8e-62,
Organism=Homo sapiens, GI110347453, Length=392, Percent_Identity=37.5, Blast_Score=225, Evalue=9e-59,
Organism=Homo sapiens, GI181337167, Length=417, Percent_Identity=35.7314148681055, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI114326544, Length=427, Percent_Identity=34.192037470726, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI114326550, Length=427, Percent_Identity=34.192037470726, Blast_Score=218, Evalue=9e-57,
Organism=Homo sapiens, GI187423910, Length=478, Percent_Identity=25.5230125523013, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7657591, Length=478, Percent_Identity=25.5230125523013, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI7657683, Length=403, Percent_Identity=28.0397022332506, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI186910308, Length=415, Percent_Identity=27.710843373494, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI186910306, Length=415, Percent_Identity=27.710843373494, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI186910304, Length=415, Percent_Identity=27.710843373494, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI115648063, Length=422, Percent_Identity=25.1184834123223, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI115648022, Length=422, Percent_Identity=25.1184834123223, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI71979932, Length=416, Percent_Identity=29.0865384615385, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI33286428, Length=418, Percent_Identity=26.3157894736842, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI9790235, Length=350, Percent_Identity=24.8571428571429, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081869, Length=478, Percent_Identity=25.3138075313808, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87082023, Length=456, Percent_Identity=24.780701754386, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081915, Length=420, Percent_Identity=24.2857142857143, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788480, Length=448, Percent_Identity=26.3392857142857, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082250, Length=464, Percent_Identity=25.2155172413793, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786302, Length=440, Percent_Identity=23.1818181818182, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081708, Length=448, Percent_Identity=22.5446428571429, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1786694, Length=417, Percent_Identity=24.4604316546763, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1790653, Length=417, Percent_Identity=21.5827338129496, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786602, Length=423, Percent_Identity=22.4586288416076, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789017, Length=398, Percent_Identity=23.6180904522613, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI2367353, Length=366, Percent_Identity=25.4098360655738, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786789, Length=345, Percent_Identity=20.8695652173913, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=413, Percent_Identity=35.1089588377724, Blast_Score=240, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17533459, Length=408, Percent_Identity=32.5980392156863, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17531343, Length=395, Percent_Identity=33.4177215189873, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17568033, Length=427, Percent_Identity=26.2295081967213, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537453, Length=371, Percent_Identity=25.8760107816712, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17540018, Length=417, Percent_Identity=26.378896882494, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71982612, Length=414, Percent_Identity=23.6714975845411, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=415, Percent_Identity=23.855421686747, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32566699, Length=379, Percent_Identity=25.065963060686, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319991, Length=368, Percent_Identity=27.9891304347826, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24668806, Length=423, Percent_Identity=36.8794326241135, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI21356285, Length=423, Percent_Identity=36.8794326241135, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI24668802, Length=423, Percent_Identity=36.8794326241135, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI221512776, Length=409, Percent_Identity=36.4303178484108, Blast_Score=261, Evalue=9e-70,
Organism=Drosophila melanogaster, GI24666159, Length=409, Percent_Identity=36.4303178484108, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24667468, Length=425, Percent_Identity=35.7647058823529, Blast_Score=253, Evalue=3e-67,
Organism=Drosophila melanogaster, GI161077963, Length=411, Percent_Identity=37.712895377129, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI281366235, Length=413, Percent_Identity=33.4140435835351, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI116007820, Length=413, Percent_Identity=33.4140435835351, Blast_Score=199, Evalue=3e-51,
Organism=Drosophila melanogaster, GI116007818, Length=413, Percent_Identity=33.4140435835351, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI85725152, Length=413, Percent_Identity=33.4140435835351, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI21357367, Length=433, Percent_Identity=27.4826789838337, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI45550968, Length=423, Percent_Identity=26.0047281323877, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921172, Length=423, Percent_Identity=26.0047281323877, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24651635, Length=418, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24651633, Length=418, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI221331183, Length=433, Percent_Identity=25.635103926097, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17647653, Length=433, Percent_Identity=25.635103926097, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24664379, Length=433, Percent_Identity=25.635103926097, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24641993, Length=407, Percent_Identity=25.7985257985258, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641995, Length=407, Percent_Identity=25.7985257985258, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004758
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50639; Mature: 50508

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFRTKNVDHMIRTGHSDTGLKKVLGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALT
CCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHH
LSFIIAALACGFAALCYAEFASTIPVSGSIYTYAYATMGELVAWIIGWDLMLEYGLATSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVGWSGYFQSLLSGFGLHLPVALTAAPGAIPGVQTLFNLPALVIMLLITTLLSFGIRES
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ARANNIMVAIKVTVVVLFIVVGVRHVQPANWQPFMPFGMEGVFGAAAIVFFAFIGFDAVT
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SAAEEVRNPKRDLPIGIIGSLAVCTILYVLVAAIMTGIVPFAKFAGVDHPVSLALQVAGE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
SWVAGFVDLGAIIGMTTVILVMAYGQTRIIFAMSRDGLLPKRLSHIHPRYATPFLNTWVV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHH
GIVFAVIAAFVPLNVLAELINIGTLAAFSLIAVAVLVLRRTRPDLHRGFRCPGVPVVPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHH
AIGMCLFLMSHLQAVTWIAFLVWVAIGLLVYFGYARRRSLLHTSEHGAAPVSETVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCC
>Mature Secondary Structure 
SLFRTKNVDHMIRTGHSDTGLKKVLGPLDLTFLGVGAIIGTGIFVLTGTGALTAGPALT
CCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHH
LSFIIAALACGFAALCYAEFASTIPVSGSIYTYAYATMGELVAWIIGWDLMLEYGLATSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSVGWSGYFQSLLSGFGLHLPVALTAAPGAIPGVQTLFNLPALVIMLLITTLLSFGIRES
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ARANNIMVAIKVTVVVLFIVVGVRHVQPANWQPFMPFGMEGVFGAAAIVFFAFIGFDAVT
CCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SAAEEVRNPKRDLPIGIIGSLAVCTILYVLVAAIMTGIVPFAKFAGVDHPVSLALQVAGE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCC
SWVAGFVDLGAIIGMTTVILVMAYGQTRIIFAMSRDGLLPKRLSHIHPRYATPFLNTWVV
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHH
GIVFAVIAAFVPLNVLAELINIGTLAAFSLIAVAVLVLRRTRPDLHRGFRCPGVPVVPLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCHHHHH
AIGMCLFLMSHLQAVTWIAFLVWVAIGLLVYFGYARRRSLLHTSEHGAAPVSETVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]