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The map label for this gene is 187929021

Identifier: 187929021

GI number: 187929021

Start: 2046895

End: 2047899

Strand: Reverse

Name: 187929021

Synonym: Rpic_1941

Alternate gene names: NA

Gene position: 2047899-2046895 (Counterclockwise)

Preceding gene: 187929024

Following gene: 187929020

Centisome position: 51.94

GC content: 64.68

Gene sequence:

>1005_bases
ATGCGCCCGAGTGCTATTTTTGTTGCGTTGCGATTTGTTATTCACATGCGGGCGTTCTATACCGACCACTTTGTCTTGCC
GCTGCCGCCGGGCCATCGGTTTCCAATGCGCAAGTACAGCGACCTGCGCGCACGGGTTCTGGCCGACGTGCCGGGGCTAT
CCATGCATGAGGCGCCGCGGGCCGATGACGACGCGTTGCTGCTGGCGCACACGTCTGAATATGTTGAGGCGGTAAGCGCC
GGGCGGCTTGACCCCGCGCGTCAGCGGGAGATCGGGTTTCCCTGGTCGCCGGAAATGGTCGAGCGCAGCCGCCGTTCGGC
GGGGGCCACGATGGCCGCGTGCGAGGCTGCGCTGGCGGATGGCATTGCCGTCAATTTGGCGGGCGGCACGCACCATGCCT
ATGCGGACAAGGGCGGCGGTTTCTGTGTATTCAACGACGCTGCCATCGCCTCGCGCTGGATTCAGCGCCGGCCGGGCAGG
ACGCCGGCGAATTTTCCGGTCGCCATCGTCGATCTCGACGTACATCAGGGCAACGGCACGGCGTCGATCCTGCGCGATGA
CGCGGCTGTTTTCACCTTGTCCTTGCATGGAGAGAAGAACTACCCGTTCCGCAAAGAAGCCTCGGATCTGGACATCGGCC
TGCACGATGGCTGCGGCGACGAGGACTATCTGCAGGCGCTGACTGGCGCTCTCGATATCCTGGCCGGGCGCTTCAAGCCA
CAGTTGATCATCTATCTGGCCGGCGCGGACCCGCACGAGGGCGATCGCCTCGGCCGGCTCAAACTGACTCTCCAGGGTCT
GGCCCGGCGCGACCAGGAAGTCTTCGATTTCGCATATCAACGGCGCATACCGATTGCCGTTACCATGGCGGGCGGCTACG
GCAACAATATCGACGATACCGTGGCCGTCCACGCGCAGACCATCGCGCTGGCTGCGCGGCACGCACAGCGCTGGGCGGCC
CGCGACGAGGCCGCCGCCTCGCACTCTCTTCCGCTTTCCGCATGA

Upstream 100 bases:

>100_bases
GTGGCAGGAAAATGCGCGTCCGTGGTGCATGCGAAATGCATTTGACCAACTCTGGCCGCAAATCCGTCTCAAAAAACATA
CGAGTGCAGCGTAGGTTACG

Downstream 100 bases:

>100_bases
CCCAAGCGTCTTCCGTCGCGCCAAACTTGGCGCGCGACTCCCTGTTTGTCGTCGCCATGCCGTGGCTGTTCGTGTTGATC
TGGAGCACGGGCTTTATCGT

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRPSAIFVALRFVIHMRAFYTDHFVLPLPPGHRFPMRKYSDLRARVLADVPGLSMHEAPRADDDALLLAHTSEYVEAVSA
GRLDPARQREIGFPWSPEMVERSRRSAGATMAACEAALADGIAVNLAGGTHHAYADKGGGFCVFNDAAIASRWIQRRPGR
TPANFPVAIVDLDVHQGNGTASILRDDAAVFTLSLHGEKNYPFRKEASDLDIGLHDGCGDEDYLQALTGALDILAGRFKP
QLIIYLAGADPHEGDRLGRLKLTLQGLARRDQEVFDFAYQRRIPIAVTMAGGYGNNIDDTVAVHAQTIALAARHAQRWAA
RDEAAASHSLPLSA

Sequences:

>Translated_334_residues
MRPSAIFVALRFVIHMRAFYTDHFVLPLPPGHRFPMRKYSDLRARVLADVPGLSMHEAPRADDDALLLAHTSEYVEAVSA
GRLDPARQREIGFPWSPEMVERSRRSAGATMAACEAALADGIAVNLAGGTHHAYADKGGGFCVFNDAAIASRWIQRRPGR
TPANFPVAIVDLDVHQGNGTASILRDDAAVFTLSLHGEKNYPFRKEASDLDIGLHDGCGDEDYLQALTGALDILAGRFKP
QLIIYLAGADPHEGDRLGRLKLTLQGLARRDQEVFDFAYQRRIPIAVTMAGGYGNNIDDTVAVHAQTIALAARHAQRWAA
RDEAAASHSLPLSA
>Mature_334_residues
MRPSAIFVALRFVIHMRAFYTDHFVLPLPPGHRFPMRKYSDLRARVLADVPGLSMHEAPRADDDALLLAHTSEYVEAVSA
GRLDPARQREIGFPWSPEMVERSRRSAGATMAACEAALADGIAVNLAGGTHHAYADKGGGFCVFNDAAIASRWIQRRPGR
TPANFPVAIVDLDVHQGNGTASILRDDAAVFTLSLHGEKNYPFRKEASDLDIGLHDGCGDEDYLQALTGALDILAGRFKP
QLIIYLAGADPHEGDRLGRLKLTLQGLARRDQEVFDFAYQRRIPIAVTMAGGYGNNIDDTVAVHAQTIALAARHAQRWAA
RDEAAASHSLPLSA

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI209862883, Length=241, Percent_Identity=32.7800829875519, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI217272877, Length=247, Percent_Identity=32.7935222672065, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI13128864, Length=281, Percent_Identity=30.6049822064057, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI8923769, Length=209, Percent_Identity=29.6650717703349, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI13128862, Length=215, Percent_Identity=27.906976744186, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI13128860, Length=263, Percent_Identity=25.4752851711027, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI20070354, Length=276, Percent_Identity=27.8985507246377, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI293336691, Length=159, Percent_Identity=30.8176100628931, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI17158039, Length=195, Percent_Identity=29.2307692307692, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI30795202, Length=195, Percent_Identity=29.2307692307692, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI30795204, Length=195, Percent_Identity=29.2307692307692, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI169234807, Length=180, Percent_Identity=30.5555555555556, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI148539870, Length=180, Percent_Identity=30.5555555555556, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI262073088, Length=182, Percent_Identity=26.3736263736264, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI262073092, Length=134, Percent_Identity=33.5820895522388, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=246, Percent_Identity=32.520325203252, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI193206283, Length=180, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540332, Length=180, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540334, Length=180, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537347, Length=257, Percent_Identity=29.1828793774319, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508561, Length=208, Percent_Identity=28.3653846153846, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17561978, Length=246, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25154022, Length=214, Percent_Identity=28.0373831775701, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25154020, Length=214, Percent_Identity=28.0373831775701, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193209491, Length=196, Percent_Identity=29.5918367346939, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534739, Length=265, Percent_Identity=25.2830188679245, Blast_Score=71, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321244, Length=292, Percent_Identity=26.7123287671233, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323999, Length=265, Percent_Identity=27.9245283018868, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324307, Length=336, Percent_Identity=25.8928571428571, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325325, Length=158, Percent_Identity=31.0126582278481, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649807, Length=251, Percent_Identity=31.8725099601594, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281360899, Length=279, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24642142, Length=279, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24642144, Length=279, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24642146, Length=279, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24657891, Length=292, Percent_Identity=25.6849315068493, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644244, Length=184, Percent_Identity=29.3478260869565, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 36366; Mature: 36366

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSAIFVALRFVIHMRAFYTDHFVLPLPPGHRFPMRKYSDLRARVLADVPGLSMHEAPR
CCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
ADDDALLLAHTSEYVEAVSAGRLDPARQREIGFPWSPEMVERSRRSAGATMAACEAALAD
CCCCEEEEEECHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHC
GIAVNLAGGTHHAYADKGGGFCVFNDAAIASRWIQRRPGRTPANFPVAIVDLDVHQGNGT
CEEEEECCCCCEEECCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCC
ASILRDDAAVFTLSLHGEKNYPFRKEASDLDIGLHDGCGDEDYLQALTGALDILAGRFKP
CEEEECCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCC
QLIIYLAGADPHEGDRLGRLKLTLQGLARRDQEVFDFAYQRRIPIAVTMAGGYGNNIDDT
EEEEEEECCCCCCCCCCEEEEEEHHHHHHCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
VAVHAQTIALAARHAQRWAARDEAAASHSLPLSA
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRPSAIFVALRFVIHMRAFYTDHFVLPLPPGHRFPMRKYSDLRARVLADVPGLSMHEAPR
CCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
ADDDALLLAHTSEYVEAVSAGRLDPARQREIGFPWSPEMVERSRRSAGATMAACEAALAD
CCCCEEEEEECHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHC
GIAVNLAGGTHHAYADKGGGFCVFNDAAIASRWIQRRPGRTPANFPVAIVDLDVHQGNGT
CEEEEECCCCCEEECCCCCCEEEECCHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCC
ASILRDDAAVFTLSLHGEKNYPFRKEASDLDIGLHDGCGDEDYLQALTGALDILAGRFKP
CEEEECCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCC
QLIIYLAGADPHEGDRLGRLKLTLQGLARRDQEVFDFAYQRRIPIAVTMAGGYGNNIDDT
EEEEEEECCCCCCCCCCEEEEEEHHHHHHCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
VAVHAQTIALAARHAQRWAARDEAAASHSLPLSA
EEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]