Click here to switch to the map view.

The map label for this gene is ompR [H]

Identifier: 187928978

GI number: 187928978

Start: 2000393

End: 2001115

Strand: Direct

Name: ompR [H]

Synonym: Rpic_1898

Alternate gene names: 187928978

Gene position: 2000393-2001115 (Clockwise)

Preceding gene: 187928974

Following gene: 187928979

Centisome position: 50.74

GC content: 62.24

Gene sequence:

>723_bases
ATGGAAAATTCCGGTCAAAAGATTCTCGTCGTCGACGACGACCCCCGCCTGCGCGACCTGCTGCGCCGCTACCTGGGGGA
ACAGGGCTTCACCGTGCTGGTGGCGGAAAACGCCACGGCCATGAACAAACTCTGGCTGCGCGAGCGCTTCGACCTGCTCG
TGCTTGACCTGATGATGCCGGGTGAAGACGGCCTGTCGATCTGCCGTCGCCTGCGCGGCGCGAACGATCAGACGCCGATC
ATCATGCTCACCGCCAAGGGCGAAGACGTCGACCGCATTGTCGGCCTTGAAATGGGCGCGGACGATTACCTCCCCAAACC
GTTCAACCCCCGCGAACTGATTGCGCGCATCCACGCCGTGCTGCGCCGCCGCGGCCCCGCCGAAATCCCGGGTGCGCCGT
CCGAGACGCCGGAAACGTTCGCTTTTGGCGATTTCGTTCTCAACCTGGCCACGCGCACGCTCAAGAAAAACGACGAAGAG
ATCACGCTCACGACGGGCGAATTCTCCGTGCTCAAGGTGTTTGCACGCCATCCGCGCCAACCCCTATCGCGCGAGAAGCT
GATGGAAATGGCGCGCGGCCGCGAATACGAAGTGTTCGATCGCAGCCTTGATGTGCAGATTTCGCGTCTGCGCAAGCTGA
TTGAACCTGACGCCAGCAACCCGCGCTTCATTCAGACCGTGTGGGGCCTGGGCTACGTGTTCATTCCCGACGGCGCCAAG
TAA

Upstream 100 bases:

>100_bases
TCGCGCGACTCGGTAAATAATGTAACCGTCTGTTTCAATTGGGCTTTTACTGCCTCCTGTTGTCGATTGGGCCCATGTTT
TTGTCGTTACCATTAGCGCC

Downstream 100 bases:

>100_bases
GCACCCGAGCAACCTTTCTCTTCCGCATCCGACTTGCGCATCCCGCGTCCGGCCGCGTTGCGGCATCTGCTGATCAGTGT
GTTTGGTTCGCTGTTCTGGC

Product: osmolarity response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MENSGQKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPI
IMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEE
ITLTTGEFSVLKVFARHPRQPLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK

Sequences:

>Translated_240_residues
MENSGQKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPI
IMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEE
ITLTTGEFSVLKVFARHPRQPLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK
>Mature_240_residues
MENSGQKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMPGEDGLSICRRLRGANDQTPI
IMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAVLRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEE
ITLTTGEFSVLKVFARHPRQPLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=234, Percent_Identity=66.6666666666667, Blast_Score=322, Evalue=1e-89,
Organism=Escherichia coli, GI1786784, Length=233, Percent_Identity=37.7682403433476, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=41.0480349344978, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786599, Length=236, Percent_Identity=37.7118644067797, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI1788394, Length=241, Percent_Identity=35.2697095435685, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=35.1931330472103, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=33.6206896551724, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=37.7682403433476, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790860, Length=230, Percent_Identity=33.4782608695652, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=32.7510917030568, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=31.304347826087, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787375, Length=234, Percent_Identity=35.4700854700855, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=231, Percent_Identity=32.4675324675325, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=30.2631578947368, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=33.6363636363636, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788905, Length=127, Percent_Identity=31.496062992126, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=133, Percent_Identity=30.8270676691729, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27309; Mature: 27309

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSGQKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMP
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHEEEECCC
GEDGLSICRRLRGANDQTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAV
CCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
LRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEEITLTTGEFSVLKVFARHPRQ
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCC
PLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK
CCCHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCC
>Mature Secondary Structure
MENSGQKILVVDDDPRLRDLLRRYLGEQGFTVLVAENATAMNKLWLRERFDLLVLDLMMP
CCCCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHEEEECCC
GEDGLSICRRLRGANDQTPIIMLTAKGEDVDRIVGLEMGADDYLPKPFNPRELIARIHAV
CCHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHEEEECCCCCCCCCCCCHHHHHHHHHHH
LRRRGPAEIPGAPSETPETFAFGDFVLNLATRTLKKNDEEITLTTGEFSVLKVFARHPRQ
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCC
PLSREKLMEMARGREYEVFDRSLDVQISRLRKLIEPDASNPRFIQTVWGLGYVFIPDGAK
CCCHHHHHHHHCCCCEEEHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]