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The map label for this gene is cyoA [H]

Identifier: 187928958

GI number: 187928958

Start: 1978260

End: 1979312

Strand: Reverse

Name: cyoA [H]

Synonym: Rpic_1877

Alternate gene names: 187928958

Gene position: 1979312-1978260 (Counterclockwise)

Preceding gene: 187928961

Following gene: 187928957

Centisome position: 50.2

GC content: 61.82

Gene sequence:

>1053_bases
ATGCCACGCTTCAATGCAGTAGTGACACCCCTTGGAATTACGGGAAGGTCGCTTTGGCGAGGTGCAGCAATTGCCTTGTT
GGTGACCCTTGCAGGCTGTAGCAACGCCGTGCTGTTGTCGCCGGCTGGCGACATGGCGGTGCGACAGCGGGACTTGATCA
TCATCGCGACATGTCTGATGTTGCTGATCATCGTCCCGGTGATCGTTCTGACCCTGTTGTTTGCATGGCGGTATCGGGAG
AGCGCTGAGAACGCGCACTACAACCCCGATTGGGATCATTCCACCGTGCTGGAGCTGGCCATCTGGGCCGCGCCGCTCCT
GATCATCATCACGCTGGGCGCCGTCACCTGGGTTAGCACCCATCAACTCGATCCGTATCGGCCGCTGACGCGGCTGGATC
AGGACCGTCCGGTGCCCGCCGAGACCAAGCCGCTTACCGTTGAGGTGGTGGCAATGGACTGGAAGTGGCTGTTCGTCTAT
CCCGAGCAGGGCATTGCCACCGTCAACGAGCTGGCCGCCCCGGTCGACCGGCCCATCGCGTTCCGGATCACAGCGACCAC
GGTCATGAACGCGTTCTTCGTGCCTTCTCTGGCGGGCATGGTCTATGCCATGCCGGGCATGGAAACCAAGCTTCATGCGG
TGATCAACCGGCCTGGCGTCTATGACGGGCTCTCTTCCAACTACAGCGGCGCGGGCTTCTCGCACATGCGGTTCAAATTC
CACGGACTGTCGAACGACGAGTTCGACCGGTGGGTCCAGCAGGTCAAGTCGTCGGGCACGTCGCTGTCGAAGGACACCTA
TCTGAAGCTGGCCAAGCCCAGCGAGAGCGAACCGGTGCAGCGTTACGCCAGCGTGGCGCCGGACCTCTATGACCGCATCC
TGAACCGCTGTGTGGATGGCCAGGCATGCCTGGCCGACACCATGGCGAGCAACCGCAACGTGAGGCGCTTCGACCCGTCG
GCGGAAATCTGTACCGCCAGCAATACGGCCGATGCCATGCCCATGTTTGCGCCGGATGCGGCCATCAACGACGGTCGAAG
GTTGTTGCGGTAG

Upstream 100 bases:

>100_bases
GTCATCACAAGACCAGAATAGCGCCTAAACTGCAACGACAAGTCGAAAGATCGTTGGGCCATCCCAGCGCGACGTTAACC
AAACGCCACTTCCGAGACCC

Downstream 100 bases:

>100_bases
GCCGGGCCTTGCCCGTTCGGCTTTTCAGCTCTTTCCGCCCCGTTGATGTTGTTCGCCAACATTGATCGGCCAGAATTGGT
CAATACAGGCACAGGTGACA

Product: ubiquinol oxidase subunit II

Products: Ubiquinone-8; H2O. [C]

Alternate protein names: Cytochrome o subunit 2; Cytochrome o ubiquinol oxidase subunit 2; Oxidase BO(3) subunit 2; Ubiquinol oxidase polypeptide II [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPRFNAVVTPLGITGRSLWRGAAIALLVTLAGCSNAVLLSPAGDMAVRQRDLIIIATCLMLLIIVPVIVLTLLFAWRYRE
SAENAHYNPDWDHSTVLELAIWAAPLLIIITLGAVTWVSTHQLDPYRPLTRLDQDRPVPAETKPLTVEVVAMDWKWLFVY
PEQGIATVNELAAPVDRPIAFRITATTVMNAFFVPSLAGMVYAMPGMETKLHAVINRPGVYDGLSSNYSGAGFSHMRFKF
HGLSNDEFDRWVQQVKSSGTSLSKDTYLKLAKPSESEPVQRYASVAPDLYDRILNRCVDGQACLADTMASNRNVRRFDPS
AEICTASNTADAMPMFAPDAAINDGRRLLR

Sequences:

>Translated_350_residues
MPRFNAVVTPLGITGRSLWRGAAIALLVTLAGCSNAVLLSPAGDMAVRQRDLIIIATCLMLLIIVPVIVLTLLFAWRYRE
SAENAHYNPDWDHSTVLELAIWAAPLLIIITLGAVTWVSTHQLDPYRPLTRLDQDRPVPAETKPLTVEVVAMDWKWLFVY
PEQGIATVNELAAPVDRPIAFRITATTVMNAFFVPSLAGMVYAMPGMETKLHAVINRPGVYDGLSSNYSGAGFSHMRFKF
HGLSNDEFDRWVQQVKSSGTSLSKDTYLKLAKPSESEPVQRYASVAPDLYDRILNRCVDGQACLADTMASNRNVRRFDPS
AEICTASNTADAMPMFAPDAAINDGRRLLR
>Mature_349_residues
PRFNAVVTPLGITGRSLWRGAAIALLVTLAGCSNAVLLSPAGDMAVRQRDLIIIATCLMLLIIVPVIVLTLLFAWRYRES
AENAHYNPDWDHSTVLELAIWAAPLLIIITLGAVTWVSTHQLDPYRPLTRLDQDRPVPAETKPLTVEVVAMDWKWLFVYP
EQGIATVNELAAPVDRPIAFRITATTVMNAFFVPSLAGMVYAMPGMETKLHAVINRPGVYDGLSSNYSGAGFSHMRFKFH
GLSNDEFDRWVQQVKSSGTSLSKDTYLKLAKPSESEPVQRYASVAPDLYDRILNRCVDGQACLADTMASNRNVRRFDPSA
EICTASNTADAMPMFAPDAAINDGRRLLR

Specific function: Cytochrome o terminal oxidase complex is the component of the aerobic respiratory chain that predominates when cells are grown at high aeration [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI1786635, Length=316, Percent_Identity=42.0886075949367, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012141
- InterPro:   IPR010514
- InterPro:   IPR008972
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759
- InterPro:   IPR006333 [H]

Pfam domain/function: PF00116 COX2; PF06481 COX_ARM [H]

EC number: 1.10.3.- [C]

Molecular weight: Translated: 38651; Mature: 38520

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFNAVVTPLGITGRSLWRGAAIALLVTLAGCSNAVLLSPAGDMAVRQRDLIIIATCLM
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCHHHHHHHHH
LLIIVPVIVLTLLFAWRYRESAENAHYNPDWDHSTVLELAIWAAPLLIIITLGAVTWVST
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HQLDPYRPLTRLDQDRPVPAETKPLTVEVVAMDWKWLFVYPEQGIATVNELAAPVDRPIA
CCCCCCCHHHHCCCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCHHHHHHHCCCCCCEE
FRITATTVMNAFFVPSLAGMVYAMPGMETKLHAVINRPGVYDGLSSNYSGAGFSHMRFKF
EEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEE
HGLSNDEFDRWVQQVKSSGTSLSKDTYLKLAKPSESEPVQRYASVAPDLYDRILNRCVDG
ECCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCHHHHHHHHHHCCCC
QACLADTMASNRNVRRFDPSAEICTASNTADAMPMFAPDAAINDGRRLLR
HHHHHHHHHCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCCCHHHCC
>Mature Secondary Structure 
PRFNAVVTPLGITGRSLWRGAAIALLVTLAGCSNAVLLSPAGDMAVRQRDLIIIATCLM
CCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCHHHHHHHHH
LLIIVPVIVLTLLFAWRYRESAENAHYNPDWDHSTVLELAIWAAPLLIIITLGAVTWVST
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HQLDPYRPLTRLDQDRPVPAETKPLTVEVVAMDWKWLFVYPEQGIATVNELAAPVDRPIA
CCCCCCCHHHHCCCCCCCCCCCCCEEEEEEEEEEEEEEEECCCCCHHHHHHHCCCCCCEE
FRITATTVMNAFFVPSLAGMVYAMPGMETKLHAVINRPGVYDGLSSNYSGAGFSHMRFKF
EEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEE
HGLSNDEFDRWVQQVKSSGTSLSKDTYLKLAKPSESEPVQRYASVAPDLYDRILNRCVDG
ECCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCHHHHHHHHHHCCCC
QACLADTMASNRNVRRFDPSAEICTASNTADAMPMFAPDAAINDGRRLLR
HHHHHHHHHCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ubiquinol-8; O(2) [C]

Specific reaction: Ubiquinol-8 + O(2) = Ubiquinone-8 + H2O. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]