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The map label for this gene is merD [H]

Identifier: 187928871

GI number: 187928871

Start: 1884087

End: 1884449

Strand: Direct

Name: merD [H]

Synonym: Rpic_1788

Alternate gene names: 187928871

Gene position: 1884087-1884449 (Clockwise)

Preceding gene: 187928870

Following gene: 187928872

Centisome position: 47.79

GC content: 65.29

Gene sequence:

>363_bases
ATGAATGCCTACACAGTGTCGCGTCTGGCCCACGATGCCAGCGTGAGCGTCAACGTGGTGCGTGACTATGCGCTGCGCGG
CCTGCTGCACCCCGCGCGCCGCACGGAGGGTGGCTATTGGCTCTACGATGCTCGGGCGCTGGCCAGATTGCGCTTCGTTC
GGGCTGCGTTCGAGGCCGGCATCGGCCTGGATGAACTGAGCCGCCTGTGTCGGGCGCTCGACGCGAACGATCGCGCCACC
TTGATCGAGTGTGTCGAGCAGTTAGGCCAGCAGATCGCGGCCCGGCAGGCAACATTGTGCGCGGTTAAGGCGGAACTGAA
CGAGCTGGCTTGCTGCGCCGACGAAGTTCGTGCCCCATCCTAG

Upstream 100 bases:

>100_bases
ACCTGACCATGGTCGAGGGACTCAAGCTTGCCGCGCAGACCTTCTCCAAGGACGTGAAGCAGCTGTCCTGCTGCGCTGGG
TGAGGCAAAGGAGGTGTTCG

Downstream 100 bases:

>100_bases
GCGGAGAGGCGTTGGCGATGATGACAACTGGATTGACCATATGAGGTGACGCGTGAGGGTTTCGGACGAGATCCGGGGTG
AACGCAAGGCAGCCGTGCTG

Product: mercuric resistence transcriptional repressor, MerD, MerR family

Products: NA

Alternate protein names: Mercuric resistance protein merD [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MNAYTVSRLAHDASVSVNVVRDYALRGLLHPARRTEGGYWLYDARALARLRFVRAAFEAGIGLDELSRLCRALDANDRAT
LIECVEQLGQQIAARQATLCAVKAELNELACCADEVRAPS

Sequences:

>Translated_120_residues
MNAYTVSRLAHDASVSVNVVRDYALRGLLHPARRTEGGYWLYDARALARLRFVRAAFEAGIGLDELSRLCRALDANDRAT
LIECVEQLGQQIAARQATLCAVKAELNELACCADEVRAPS
>Mature_120_residues
MNAYTVSRLAHDASVSVNVVRDYALRGLLHPARRTEGGYWLYDARALARLRFVRAAFEAGIGLDELSRLCRALDANDRAT
LIECVEQLGQQIAARQATLCAVKAELNELACCADEVRAPS

Specific function: Zinc-Responsive Transcriptional Regulator Of Znta. [C]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR011797 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 13177; Mature: 13177

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAYTVSRLAHDASVSVNVVRDYALRGLLHPARRTEGGYWLYDARALARLRFVRAAFEAG
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHC
IGLDELSRLCRALDANDRATLIECVEQLGQQIAARQATLCAVKAELNELACCADEVRAPS
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNAYTVSRLAHDASVSVNVVRDYALRGLLHPARRTEGGYWLYDARALARLRFVRAAFEAG
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHCHHHHCCCCEEEHHHHHHHHHHHHHHHHHHC
IGLDELSRLCRALDANDRATLIECVEQLGQQIAARQATLCAVKAELNELACCADEVRAPS
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8302940; 9159519 [H]