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The map label for this gene is 187928497

Identifier: 187928497

GI number: 187928497

Start: 1501541

End: 1503016

Strand: Direct

Name: 187928497

Synonym: Rpic_1411

Alternate gene names: NA

Gene position: 1501541-1503016 (Clockwise)

Preceding gene: 187928496

Following gene: 187928499

Centisome position: 38.09

GC content: 67.34

Gene sequence:

>1476_bases
ATGCAAGCGAATCCGAGCCACGCTGCAACACCTGCGGCCGCCAACGAAGAGATCGTCCAATGGAGCGCGATCGAACTGTC
CCGGCGTATCCACGCGCGCGATGTGTCGTGCGTGGAAGTCATGGAAGCGTTCCTTGCGCAGATCGATCGTCATAACCCGA
CGGTCAATGCCGTCGTGGCCCGCATCGATGCCGAATCCGCCATCGACCAGGCACGCGAGCGGGATGTGCTGCTGTCGCAA
GGTTTGTCCGGCGGCTGGATGCATGGCTTTCCGCAGGCGCCGAAGGATCTTGCGGCCACCGCGGGCATGGTGACGGCGAT
GGGCAGTCTCGCCATGGCGCGCAACGTGCCGACGCATGACAGCATCGTCGTCGAGCGCATTCGCCGGCAAGGCACGGTGT
TGATCGGCAAGACGAATACGCCTGAGTTCGGGCTCGGCTCGCACACCTACAACCGCGTGTACGGCACTACGCGCAACGCC
TGGAACCCCGAGCGCTCGGCCGGCGGCAGCAGCGGTGGCACGGCCGCCGCGCTGGCGCTGAACATGCTGCCCGTGGCCGA
CGGCAGCGACATGATGGGCTCGCTGCGCAACCCCGCGGCCTGGAACAACATCTACGGCCTGCGTCCGAGCCTCGGTCGCG
TGCCTTACGGACCGACCGGCGACGTGTTCTTCCAGCAGTTGGGCACTGAAGGCCCCATGGCGCGCAATCCGCACGACCTC
GCGTGGCTGCTCGCCACGCAGGCCGGCTACGACCCGCGTGCGCCGCTGTCGCTGAGTGACGATCCGGCGTGCTTCATGCA
GCCGCTGCACCGGGATTTCCGGCAGGCCCGCATTGGCTGGTTGGGAGATTTCGGTGGCTACCTTGCCGTCGACCGCGAAG
TGCTGGCCGTCAACGAGCATGCGCTCGACACGTTCGACACGCTGGGCTGCCATGTCGAGACCGTGCGGCCCTTCTTCGCC
ATGGACGCGCTATGGGAATGCTGGTGCACGCTGCGCGCGCTGAGCGTGTCCGGCAACCTCGGCCTGCTGTACGCCAACGC
CGCCACGCGCGATTTGCTCAAGCCCGAAGCGATCTGGGAAATTGAGCACGGACGCAGCCGCACCGCCATCGACATCCACC
GAGCCATCGCCACACGGGCAAGCTGGTACCAGGCGCTGCTGCGGCAGTTTGCGCACTACGATTTCCTCGTCCTGCCTTGC
ACGCAGGTTGCGCCCTTCCCCGCCGAAGAGCACTGGCCCAAGGCCGCAGCAGGCCGCGCGATGGACACATACCACCGCTG
GATGGAAGTCGTGATTGGCGCCACGCTGGCGGGCGTGCCGGCCGCGAGCCTGCCGTCGGGCTTGACCGCCGATGGCCTGC
CGCTGGGCCTGCAGGTGATTGCGCCGCCCCGGTCGGAGTTTGCGTTGCTGCAGCTTGCGGCCGCGTGGCACGAAGCGTTC
GCGCCGGCACGTGCCGCGTCGCCGCTATTGGGCTGA

Upstream 100 bases:

>100_bases
ACGATTTCAACGACCAGGTGTTGCCGTTGGGCGCAGCCGCCTGGGTGCGTCTGGCGCAGGCCTATCTGACCGCCGCGTGA
AGTGAACTTCGAGTCAAGCA

Downstream 100 bases:

>100_bases
GCGATGCACACGTGCCGTGTTTTCCCGGCACGCGCATAGCCAATCCCACACCGCGCGCACGGCAGCGTCTTCAAGCCGCG
CAGATGGCGCCACGGCCCAG

Product: Amidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MQANPSHAATPAAANEEIVQWSAIELSRRIHARDVSCVEVMEAFLAQIDRHNPTVNAVVARIDAESAIDQARERDVLLSQ
GLSGGWMHGFPQAPKDLAATAGMVTAMGSLAMARNVPTHDSIVVERIRRQGTVLIGKTNTPEFGLGSHTYNRVYGTTRNA
WNPERSAGGSSGGTAAALALNMLPVADGSDMMGSLRNPAAWNNIYGLRPSLGRVPYGPTGDVFFQQLGTEGPMARNPHDL
AWLLATQAGYDPRAPLSLSDDPACFMQPLHRDFRQARIGWLGDFGGYLAVDREVLAVNEHALDTFDTLGCHVETVRPFFA
MDALWECWCTLRALSVSGNLGLLYANAATRDLLKPEAIWEIEHGRSRTAIDIHRAIATRASWYQALLRQFAHYDFLVLPC
TQVAPFPAEEHWPKAAAGRAMDTYHRWMEVVIGATLAGVPAASLPSGLTADGLPLGLQVIAPPRSEFALLQLAAAWHEAF
APARAASPLLG

Sequences:

>Translated_491_residues
MQANPSHAATPAAANEEIVQWSAIELSRRIHARDVSCVEVMEAFLAQIDRHNPTVNAVVARIDAESAIDQARERDVLLSQ
GLSGGWMHGFPQAPKDLAATAGMVTAMGSLAMARNVPTHDSIVVERIRRQGTVLIGKTNTPEFGLGSHTYNRVYGTTRNA
WNPERSAGGSSGGTAAALALNMLPVADGSDMMGSLRNPAAWNNIYGLRPSLGRVPYGPTGDVFFQQLGTEGPMARNPHDL
AWLLATQAGYDPRAPLSLSDDPACFMQPLHRDFRQARIGWLGDFGGYLAVDREVLAVNEHALDTFDTLGCHVETVRPFFA
MDALWECWCTLRALSVSGNLGLLYANAATRDLLKPEAIWEIEHGRSRTAIDIHRAIATRASWYQALLRQFAHYDFLVLPC
TQVAPFPAEEHWPKAAAGRAMDTYHRWMEVVIGATLAGVPAASLPSGLTADGLPLGLQVIAPPRSEFALLQLAAAWHEAF
APARAASPLLG
>Mature_491_residues
MQANPSHAATPAAANEEIVQWSAIELSRRIHARDVSCVEVMEAFLAQIDRHNPTVNAVVARIDAESAIDQARERDVLLSQ
GLSGGWMHGFPQAPKDLAATAGMVTAMGSLAMARNVPTHDSIVVERIRRQGTVLIGKTNTPEFGLGSHTYNRVYGTTRNA
WNPERSAGGSSGGTAAALALNMLPVADGSDMMGSLRNPAAWNNIYGLRPSLGRVPYGPTGDVFFQQLGTEGPMARNPHDL
AWLLATQAGYDPRAPLSLSDDPACFMQPLHRDFRQARIGWLGDFGGYLAVDREVLAVNEHALDTFDTLGCHVETVRPFFA
MDALWECWCTLRALSVSGNLGLLYANAATRDLLKPEAIWEIEHGRSRTAIDIHRAIATRASWYQALLRQFAHYDFLVLPC
TQVAPFPAEEHWPKAAAGRAMDTYHRWMEVVIGATLAGVPAASLPSGLTADGLPLGLQVIAPPRSEFALLQLAAAWHEAF
APARAASPLLG

Specific function: Unknown

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI195972892, Length=514, Percent_Identity=24.9027237354086, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI222831590, Length=509, Percent_Identity=27.3084479371316, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI166795287, Length=214, Percent_Identity=29.4392523364486, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537465, Length=518, Percent_Identity=25.4826254826255, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17538252, Length=516, Percent_Identity=22.8682170542636, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17556264, Length=294, Percent_Identity=27.2108843537415, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71990152, Length=392, Percent_Identity=26.0204081632653, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17543272, Length=132, Percent_Identity=36.3636363636364, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17556276, Length=272, Percent_Identity=27.2058823529412, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17556278, Length=272, Percent_Identity=27.2058823529412, Blast_Score=72, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319685, Length=465, Percent_Identity=26.4516129032258, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6320448, Length=242, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323950, Length=416, Percent_Identity=23.7980769230769, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648435, Length=505, Percent_Identity=27.1287128712871, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24648437, Length=505, Percent_Identity=27.1287128712871, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45550774, Length=505, Percent_Identity=27.1287128712871, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24644968, Length=503, Percent_Identity=23.8568588469185, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24652985, Length=515, Percent_Identity=28.5436893203883, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI19922090, Length=515, Percent_Identity=28.5436893203883, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24652981, Length=515, Percent_Identity=28.5436893203883, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24652983, Length=515, Percent_Identity=28.5436893203883, Blast_Score=105, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21356731, Length=261, Percent_Identity=31.4176245210728, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24648441, Length=427, Percent_Identity=27.4004683840749, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24648439, Length=427, Percent_Identity=27.4004683840749, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI161078093, Length=523, Percent_Identity=24.4741873804971, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24648113, Length=508, Percent_Identity=28.1496062992126, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: =3.5.1.4 [H]

Molecular weight: Translated: 53146; Mature: 53146

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQANPSHAATPAAANEEIVQWSAIELSRRIHARDVSCVEVMEAFLAQIDRHNPTVNAVVA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHEE
RIDAESAIDQARERDVLLSQGLSGGWMHGFPQAPKDLAATAGMVTAMGSLAMARNVPTHD
HHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCH
SIVVERIRRQGTVLIGKTNTPEFGLGSHTYNRVYGTTRNAWNPERSAGGSSGGTAAALAL
HHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
NMLPVADGSDMMGSLRNPAAWNNIYGLRPSLGRVPYGPTGDVFFQQLGTEGPMARNPHDL
HHEECCCCHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHH
AWLLATQAGYDPRAPLSLSDDPACFMQPLHRDFRQARIGWLGDFGGYLAVDREVLAVNEH
EEEEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCEEEECCEEEEECHH
ALDTFDTLGCHVETVRPFFAMDALWECWCTLRALSVSGNLGLLYANAATRDLLKPEAIWE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCHHHHHCCCHHEEE
IEHGRSRTAIDIHRAIATRASWYQALLRQFAHYDFLVLPCTQVAPFPAEEHWPKAAAGRA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCHHCCCH
MDTYHRWMEVVIGATLAGVPAASLPSGLTADGLPLGLQVIAPPRSEFALLQLAAAWHEAF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
APARAASPLLG
CCHHHCCCCCC
>Mature Secondary Structure
MQANPSHAATPAAANEEIVQWSAIELSRRIHARDVSCVEVMEAFLAQIDRHNPTVNAVVA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHEE
RIDAESAIDQARERDVLLSQGLSGGWMHGFPQAPKDLAATAGMVTAMGSLAMARNVPTHD
HHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCH
SIVVERIRRQGTVLIGKTNTPEFGLGSHTYNRVYGTTRNAWNPERSAGGSSGGTAAALAL
HHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
NMLPVADGSDMMGSLRNPAAWNNIYGLRPSLGRVPYGPTGDVFFQQLGTEGPMARNPHDL
HHEECCCCHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHH
AWLLATQAGYDPRAPLSLSDDPACFMQPLHRDFRQARIGWLGDFGGYLAVDREVLAVNEH
EEEEEHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHCCCCEEEECCEEEEECHH
ALDTFDTLGCHVETVRPFFAMDALWECWCTLRALSVSGNLGLLYANAATRDLLKPEAIWE
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCHHHHHCCCHHEEE
IEHGRSRTAIDIHRAIATRASWYQALLRQFAHYDFLVLPCTQVAPFPAEEHWPKAAAGRA
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHCCCCHHCCCH
MDTYHRWMEVVIGATLAGVPAASLPSGLTADGLPLGLQVIAPPRSEFALLQLAAAWHEAF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
APARAASPLLG
CCHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]