| Definition | Ralstonia pickettii 12J chromosome chromosome 1, complete sequence. |
|---|---|
| Accession | NC_010682 |
| Length | 3,942,557 |
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The map label for this gene is dxr
Identifier: 187928373
GI number: 187928373
Start: 1378882
End: 1380072
Strand: Direct
Name: dxr
Synonym: Rpic_1284
Alternate gene names: 187928373
Gene position: 1378882-1380072 (Clockwise)
Preceding gene: 187928372
Following gene: 187928374
Centisome position: 34.97
GC content: 64.82
Gene sequence:
>1191_bases ATGATGCGTTTGACCGTTCTTGGCGCCACTGGCTCCATTGGCGACAGCACGCTCGACGTGGTGCGCCGTCATCCCGACAA ATACAGCGTTTTTGCGCTGACCGCCAACGCGCAGGCCGACAAGCTCGCGGTGCTCTGCCGTGAGTTTCGCCCGAAGATGG CGGTGCTCGGTTCGGCGGCTGCGGCGGATGCATTGCGTGACCAACTGGGCACAGAAGCTGCCGGCATCGAAATCTGTTCT GGCACCAAGGCGCTGGAAGAGGCCGCCGCCCACCCTGACTGCGATGCCGTGATGGCCGCCATCGTTGGGGCGGCAGGTTT GCGCCCGACGCTTGCCGCCGTGCGCGCCGGCAAGCGCGTGCTCCTGGCCAACAAGGAGGCGCTGGTGATGTCCGGCGCGC TCTTCATGGACGCCGTGCGTGAGCATGGCGCCACCGTGCTCCCGATCGACAGCGAGCACAACGCCATCTTCCAATGCCTT CCTCAGCAAGTTCCGCAGTTCGGGCGCGGCGTGTCGCGCATCGTCCTGACGGCATCAGGTGGTCCGTTCCGTACGCGTGC CGTTGATTCGCTTGCTGATGTCACGCCCGATCAGGCTTGCGCGCATCCGAACTGGGTGATGGGGCGCAAGATCTCCGTTG ACTCCGCCACCATGATGAACAAGGGGCTGGAGGTGATCGAGGCGTACTGGCTGTTTGGCGTGCCGGTCGAGCATCTCGAA GTGCTGATCCACCCGCAGAGTGTCATCCATTCGATGGTCGGCTACGACGATGGCTCCGTGCTGGCGCAGCTGGGCAATCC GGACATGCGCACGCCGATTGCCTACGGCTTGGCCTACCCTGAGCGCATTGAGGCCGGTGTTCCGCTGCTCGATCTCGTGA CCACAGGTGCACTGACGTTCGAGGCGCCGGATCTGCGCCGCTTCCCGTGTCTGGCGCTGGCCTTTGATGCACTGCGCGCC GGTGGTACGGCACCTGCTGCTCTGAACGCGGCCAACGAGGTGGCTGTCGAAGCATTTTTACAGCGCCGCATCCGGTTCAC CGAGATTGCTGCCGTGGTGGGTGACACGCTCGCCCGTACTTCTATCGTGCCCGCCGACTCGCTCGACACCGTATTTGCGG CCGACGCCCAAGCGCGTCAGCAGGCGGAGCGCTATATCGCGACCGCATGCGCGCAACTGCCGGCCGCCTGA
Upstream 100 bases:
>100_bases GCCGCCTGTTGCCCGGCCACGGCGGTGTGCTCGATCGTATCGACGCACTGCTGCCAGTGTTTCCGCTGGCTGCGCTGCTG ATTTCCTGAGGCGTCTGAAC
Downstream 100 bases:
>100_bases AAGCGCCCCGTCAGAGCAAGCGGGTAACATAGCGGCTTCGCGCGGGGTCAACCAGCGCGTGCCCTTCAGTGCATCCGGAG AAGGTTTTGCAGACCGTTTT
Product: 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Products: NA
Alternate protein names: DXP reductoisomerase; 1-deoxyxylulose-5-phosphate reductoisomerase; 2-C-methyl-D-erythritol 4-phosphate synthase
Number of amino acids: Translated: 396; Mature: 396
Protein sequence:
>396_residues MMRLTVLGATGSIGDSTLDVVRRHPDKYSVFALTANAQADKLAVLCREFRPKMAVLGSAAAADALRDQLGTEAAGIEICS GTKALEEAAAHPDCDAVMAAIVGAAGLRPTLAAVRAGKRVLLANKEALVMSGALFMDAVREHGATVLPIDSEHNAIFQCL PQQVPQFGRGVSRIVLTASGGPFRTRAVDSLADVTPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAYWLFGVPVEHLE VLIHPQSVIHSMVGYDDGSVLAQLGNPDMRTPIAYGLAYPERIEAGVPLLDLVTTGALTFEAPDLRRFPCLALAFDALRA GGTAPAALNAANEVAVEAFLQRRIRFTEIAAVVGDTLARTSIVPADSLDTVFAADAQARQQAERYIATACAQLPAA
Sequences:
>Translated_396_residues MMRLTVLGATGSIGDSTLDVVRRHPDKYSVFALTANAQADKLAVLCREFRPKMAVLGSAAAADALRDQLGTEAAGIEICS GTKALEEAAAHPDCDAVMAAIVGAAGLRPTLAAVRAGKRVLLANKEALVMSGALFMDAVREHGATVLPIDSEHNAIFQCL PQQVPQFGRGVSRIVLTASGGPFRTRAVDSLADVTPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAYWLFGVPVEHLE VLIHPQSVIHSMVGYDDGSVLAQLGNPDMRTPIAYGLAYPERIEAGVPLLDLVTTGALTFEAPDLRRFPCLALAFDALRA GGTAPAALNAANEVAVEAFLQRRIRFTEIAAVVGDTLARTSIVPADSLDTVFAADAQARQQAERYIATACAQLPAA >Mature_396_residues MMRLTVLGATGSIGDSTLDVVRRHPDKYSVFALTANAQADKLAVLCREFRPKMAVLGSAAAADALRDQLGTEAAGIEICS GTKALEEAAAHPDCDAVMAAIVGAAGLRPTLAAVRAGKRVLLANKEALVMSGALFMDAVREHGATVLPIDSEHNAIFQCL PQQVPQFGRGVSRIVLTASGGPFRTRAVDSLADVTPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAYWLFGVPVEHLE VLIHPQSVIHSMVGYDDGSVLAQLGNPDMRTPIAYGLAYPERIEAGVPLLDLVTTGALTFEAPDLRRFPCLALAFDALRA GGTAPAALNAANEVAVEAFLQRRIRFTEIAAVVGDTLARTSIVPADSLDTVFAADAQARQQAERYIATACAQLPAA
Specific function: Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COG id: COG0743
COG function: function code I; 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the DXR family
Homologues:
Organism=Escherichia coli, GI1786369, Length=393, Percent_Identity=55.470737913486, Blast_Score=411, Evalue=1e-116,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): DXR_RALPJ (B2UB12)
Other databases:
- EMBL: CP001068 - RefSeq: YP_001898860.1 - ProteinModelPortal: B2UB12 - SMR: B2UB12 - GeneID: 6289310 - GenomeReviews: CP001068_GR - KEGG: rpi:Rpic_1284 - HOGENOM: HBG430762 - OMA: IHSMVEY - ProtClustDB: PRK05447 - HAMAP: MF_00183 - InterPro: IPR003821 - InterPro: IPR013644 - InterPro: IPR013512 - InterPro: IPR016040 - Gene3D: G3DSA:3.40.50.720 - PIRSF: PIRSF006205 - TIGRFAMs: TIGR00243
Pfam domain/function: PF08436 DXP_redisom_C; PF02670 DXP_reductoisom
EC number: =1.1.1.267
Molecular weight: Translated: 41790; Mature: 41790
Theoretical pI: Translated: 5.41; Mature: 5.41
Prosite motif: NA
Important sites: BINDING 125-125 BINDING 152-152 BINDING 179-179 BINDING 202-202 BINDING 224-224
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MMRLTVLGATGSIGDSTLDVVRRHPDKYSVFALTANAQADKLAVLCREFRPKMAVLGSAA CEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHH AADALRDQLGTEAAGIEICSGTKALEEAAAHPDCDAVMAAIVGAAGLRPTLAAVRAGKRV HHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEE LLANKEALVMSGALFMDAVREHGATVLPIDSEHNAIFQCLPQQVPQFGRGVSRIVLTASG EEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECC GPFRTRAVDSLADVTPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAYWLFGVPVEHLE CCCHHHHHHHHHHCCCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCHHHHH VLIHPQSVIHSMVGYDDGSVLAQLGNPDMRTPIAYGLAYPERIEAGVPLLDLVTTGALTF EEECCHHHHHHHHCCCCCHHHEECCCCCCCCCHHHHCCCHHHHHCCCCHHHHHHCCCEEE EAPDLRRFPCLALAFDALRAGGTAPAALNAANEVAVEAFLQRRIRFTEIAAVVGDTLART CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SIVPADSLDTVFAADAQARQQAERYIATACAQLPAA CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure MMRLTVLGATGSIGDSTLDVVRRHPDKYSVFALTANAQADKLAVLCREFRPKMAVLGSAA CEEEEEEECCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHH AADALRDQLGTEAAGIEICSGTKALEEAAAHPDCDAVMAAIVGAAGLRPTLAAVRAGKRV HHHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCEE LLANKEALVMSGALFMDAVREHGATVLPIDSEHNAIFQCLPQQVPQFGRGVSRIVLTASG EEECCCHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEEECC GPFRTRAVDSLADVTPDQACAHPNWVMGRKISVDSATMMNKGLEVIEAYWLFGVPVEHLE CCCHHHHHHHHHHCCCHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCHHHHH VLIHPQSVIHSMVGYDDGSVLAQLGNPDMRTPIAYGLAYPERIEAGVPLLDLVTTGALTF EEECCHHHHHHHHCCCCCHHHEECCCCCCCCCHHHHCCCHHHHHCCCCHHHHHHCCCEEE EAPDLRRFPCLALAFDALRAGGTAPAALNAANEVAVEAFLQRRIRFTEIAAVVGDTLART CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH SIVPADSLDTVFAADAQARQQAERYIATACAQLPAA CCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA