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The map label for this gene is dapD [H]

Identifier: 187928355

GI number: 187928355

Start: 1354300

End: 1355127

Strand: Reverse

Name: dapD [H]

Synonym: Rpic_1266

Alternate gene names: 187928355

Gene position: 1355127-1354300 (Counterclockwise)

Preceding gene: 187928356

Following gene: 187928354

Centisome position: 34.37

GC content: 64.61

Gene sequence:

>828_bases
ATGACGCAACAACTGCAATCCCTGATCGACCAAGCGTGGGAAGACCGCGCCAACCTGTCGCCCAAGTCCGCTCCGGCCGA
TGTCCGTGAAGCCGTCGCCAACGTGATCGGCCAGCTCGATCGTGGCGCGCTGCGCGTGGCCGAGAAGCAGGACGGCGAGT
GGATCGTCAATCAGTGGATCAAGAAAGCCGTGCTGCTGTCGTTCCGCCTGGAAGACAACGCGCCGATGGCTGCCGGCGGC
TTCACGCAGTTCTACGACAAGGTGCCGAGCAAGTTCGCCAACTACACGGCCGAAGACTTCGCGGCGGGCGGCTTCCGCGT
GGTGCCGCCGGCCGTGGCGCGCCGTGGCTCGTTCATCGCCAAGAACGCCGTGCTGATGCCGTCGTACGTGAACATCGGCG
CCTATGTGGATGAAGGCACGATGGTCGACACGTGGGCCACCGTCGGTTCGTGCGCACAGATCGGCAAGAACGTCCACCTG
TCGGGCGGCGTGGGCATCGGCGGCGTGCTGGAGCCGCTGCAGGCCAACCCGGTCATCATCGAAGACAACTGCTTCATCGG
TGCCCGCTCGGAAGTGGTGGAAGGCGTGATCGTTGAAGAAAACTCGGTGATCTCGATGGGCGTGTACCTGGGCCAGTCGA
CCAAGATCTACGACCGCGAAACCGGTGAAGTCAGCTACGGCCGCATCCCGGCGGGCTCGGTGGTGGTGGCGGGCAACCTG
CCGTCGAAGGACGGCTCGCACAGCCTGTACTGCGCCGTGATCGTCAAGAAGGTCGACGCCAAGACGCGCGCCAAGGTTGG
CCTGAACGAGCTGCTGCGCGGCGACTAA

Upstream 100 bases:

>100_bases
GACGAATGCCTGGAAGGCGCCCGCCGCATCGTCGAGTTCTGCCAGCAACGCTGATCCTGAATTTTTCTCTTCTGTTTCCT
CTCCGAGAGCCAACAAGACC

Downstream 100 bases:

>100_bases
GCCCCGGCGCAAGGCATGCCTGCTAGTCTTGCAGGCATGCCAACCACTTCAAGCGCAGCAATGTCCGAACACAATGCCAC
CGGCACCCGCTTCGGCAAGC

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase [H]

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MTQQLQSLIDQAWEDRANLSPKSAPADVREAVANVIGQLDRGALRVAEKQDGEWIVNQWIKKAVLLSFRLEDNAPMAAGG
FTQFYDKVPSKFANYTAEDFAAGGFRVVPPAVARRGSFIAKNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHL
SGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVSYGRIPAGSVVVAGNL
PSKDGSHSLYCAVIVKKVDAKTRAKVGLNELLRGD

Sequences:

>Translated_275_residues
MTQQLQSLIDQAWEDRANLSPKSAPADVREAVANVIGQLDRGALRVAEKQDGEWIVNQWIKKAVLLSFRLEDNAPMAAGG
FTQFYDKVPSKFANYTAEDFAAGGFRVVPPAVARRGSFIAKNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHL
SGGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVSYGRIPAGSVVVAGNL
PSKDGSHSLYCAVIVKKVDAKTRAKVGLNELLRGD
>Mature_274_residues
TQQLQSLIDQAWEDRANLSPKSAPADVREAVANVIGQLDRGALRVAEKQDGEWIVNQWIKKAVLLSFRLEDNAPMAAGGF
TQFYDKVPSKFANYTAEDFAAGGFRVVPPAVARRGSFIAKNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLS
GGVGIGGVLEPLQANPVIIEDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVSYGRIPAGSVVVAGNLP
SKDGSHSLYCAVIVKKVDAKTRAKVGLNELLRGD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786362, Length=271, Percent_Identity=75.6457564575646, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.117 [H]

Molecular weight: Translated: 29390; Mature: 29259

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQLQSLIDQAWEDRANLSPKSAPADVREAVANVIGQLDRGALRVAEKQDGEWIVNQWI
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHH
KKAVLLSFRLEDNAPMAAGGFTQFYDKVPSKFANYTAEDFAAGGFRVVPPAVARRGSFIA
HHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCEEECCHHHHHCCCEEE
KNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVII
CCEEECCCEECCCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCEEE
EDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVSYGRIPAGSVVVAGNL
ECCCEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEECCCCCCCCEEEECCC
PSKDGSHSLYCAVIVKKVDAKTRAKVGLNELLRGD
CCCCCCCCEEEEEEEHHHCCHHHHHHCHHHHHCCC
>Mature Secondary Structure 
TQQLQSLIDQAWEDRANLSPKSAPADVREAVANVIGQLDRGALRVAEKQDGEWIVNQWI
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHH
KKAVLLSFRLEDNAPMAAGGFTQFYDKVPSKFANYTAEDFAAGGFRVVPPAVARRGSFIA
HHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCEEECCHHHHHCCCEEE
KNAVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQANPVII
CCEEECCCEECCCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCHHCCCCCCCCEEE
EDNCFIGARSEVVEGVIVEENSVISMGVYLGQSTKIYDRETGEVSYGRIPAGSVVVAGNL
ECCCEECCHHHHHCEEEECCCCEEEEEEEECCCCEEEECCCCCEECCCCCCCCEEEECCC
PSKDGSHSLYCAVIVKKVDAKTRAKVGLNELLRGD
CCCCCCCCEEEEEEEHHHCCHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA