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The map label for this gene is dapL [H]

Identifier: 187928356

GI number: 187928356

Start: 1355174

End: 1356373

Strand: Reverse

Name: dapL [H]

Synonym: Rpic_1267

Alternate gene names: 187928356

Gene position: 1356373-1355174 (Counterclockwise)

Preceding gene: 187928364

Following gene: 187928355

Centisome position: 34.4

GC content: 65.75

Gene sequence:

>1200_bases
GTGAATCCGCGCCTGTCCGCCCTGCAGCCGTATCCGTTCGAGAAACTGAAAGCGCTTGTGAAGGACGTCACGCCCAGCGC
CGTCCATACGCCGATCAGCTTCGGGATCGGTGAACCCAAGCACCCGACGCCGGCCCTGGTGAAAGACGCGCTGACGGCGG
CGCTTGGCGGGCTGGCGAATTATCCCACGACGCTCGGTTCCGATGCACTGCGACAGTGCATCGCTGCATGGCTGGAGCGC
CGCTACGGCTTGCCGAAGGTCGACCCAGCCACTGAAGTCATCCCCGTCAACGGCTCGCGCGAGGCGCTGTTCTCGTTCGC
GCAGACCGTGATTGACGGCAGCAAGCCCGGCGCCCGCGTGCTGTGCCCGAACCCGTTCTATCAAATCTACGAAGGCTCGG
CGCTGCTGGCCGGCGCCACGCCGCTGTTCGCCAACAGCGACCCGGCGCGCAACTACGCGCCCGAGTTTGCCGCGATCACG
CCCGAAGAATGGCGCAACGTGCAGCTCGTCTTCGTATGCAGCCCGGGCAACCCGACCGGCGCCGTGCTCACGCTCGAAGA
CTGGAAGCAGCTCTTCGCGCTGTCGGATGAATATGGCTTCATCATTGCGTCGGACGAGTGCTATTCCGAGATCTATTTCG
ACGAGACCAACCCGCCGCTGGGCGCCCTGCAGGCCGCGCACCAGCTGGGCCGCGGCTTTGACCGCCTGGTGATGTTCTCG
AGCCTTTCGAAGCGCTCCAACGTGCCGGGCATGCGCTCCGGTTTCGTGGCCGGCGACGCCAAGCTGCTCAAGGCCTATCT
GCTGTATCGCACGTATCACGGCAGCGCGATGAGCCCGTCGGTGCAGTCCGCTAGCATCGCTGCGTGGAATGACGAGACCC
ACGTGCGCGACAACCGCGCGCAATACGTCAAGAAGTTCCAGCAGGTCACGCCGATGCTGGCCGAGGTGCTGGACGTGGCC
CTGCCCGATGCAGCCTTCTACCTCTGGGCCAACGTCAAGCGCACGGGCCTGTCGGACACTGAATTCGCGCGCCAGTTGCT
GGCCGCCAAGAACGTCGCCGTGCTGCCCGGAAGCTACCTCGCCCGCGAGGCGCACGGCACGAATCCGGGCCAGGACTACG
TGCGCATCGCGCTGGTAGCCGGCGTGGACGAATGCCTGGAAGGCGCCCGCCGCATCGTCGAGTTCTGCCAGCAACGCTGA

Upstream 100 bases:

>100_bases
TTGTCGTGGGGCGGCCAGCACACGTTGGCCGTATAATTTCGGGCTTCCCGGCAAGCGCCAAGCTTGCCCGCCAACCAGCC
CAACACCGCCGCCCAACACC

Downstream 100 bases:

>100_bases
TCCTGAATTTTTCTCTTCTGTTTCCTCTCCGAGAGCCAACAAGACCATGACGCAACAACTGCAATCCCTGATCGACCAAG
CGTGGGAAGACCGCGCCAAC

Product: succinyldiaminopimelate transaminase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNPRLSALQPYPFEKLKALVKDVTPSAVHTPISFGIGEPKHPTPALVKDALTAALGGLANYPTTLGSDALRQCIAAWLER
RYGLPKVDPATEVIPVNGSREALFSFAQTVIDGSKPGARVLCPNPFYQIYEGSALLAGATPLFANSDPARNYAPEFAAIT
PEEWRNVQLVFVCSPGNPTGAVLTLEDWKQLFALSDEYGFIIASDECYSEIYFDETNPPLGALQAAHQLGRGFDRLVMFS
SLSKRSNVPGMRSGFVAGDAKLLKAYLLYRTYHGSAMSPSVQSASIAAWNDETHVRDNRAQYVKKFQQVTPMLAEVLDVA
LPDAAFYLWANVKRTGLSDTEFARQLLAAKNVAVLPGSYLAREAHGTNPGQDYVRIALVAGVDECLEGARRIVEFCQQR

Sequences:

>Translated_399_residues
MNPRLSALQPYPFEKLKALVKDVTPSAVHTPISFGIGEPKHPTPALVKDALTAALGGLANYPTTLGSDALRQCIAAWLER
RYGLPKVDPATEVIPVNGSREALFSFAQTVIDGSKPGARVLCPNPFYQIYEGSALLAGATPLFANSDPARNYAPEFAAIT
PEEWRNVQLVFVCSPGNPTGAVLTLEDWKQLFALSDEYGFIIASDECYSEIYFDETNPPLGALQAAHQLGRGFDRLVMFS
SLSKRSNVPGMRSGFVAGDAKLLKAYLLYRTYHGSAMSPSVQSASIAAWNDETHVRDNRAQYVKKFQQVTPMLAEVLDVA
LPDAAFYLWANVKRTGLSDTEFARQLLAAKNVAVLPGSYLAREAHGTNPGQDYVRIALVAGVDECLEGARRIVEFCQQR
>Mature_399_residues
MNPRLSALQPYPFEKLKALVKDVTPSAVHTPISFGIGEPKHPTPALVKDALTAALGGLANYPTTLGSDALRQCIAAWLER
RYGLPKVDPATEVIPVNGSREALFSFAQTVIDGSKPGARVLCPNPFYQIYEGSALLAGATPLFANSDPARNYAPEFAAIT
PEEWRNVQLVFVCSPGNPTGAVLTLEDWKQLFALSDEYGFIIASDECYSEIYFDETNPPLGALQAAHQLGRGFDRLVMFS
SLSKRSNVPGMRSGFVAGDAKLLKAYLLYRTYHGSAMSPSVQSASIAAWNDETHVRDNRAQYVKKFQQVTPMLAEVLDVA
LPDAAFYLWANVKRTGLSDTEFARQLLAAKNVAVLPGSYLAREAHGTNPGQDYVRIALVAGVDECLEGARRIVEFCQQR

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=393, Percent_Identity=22.64631043257, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI56713254, Length=393, Percent_Identity=22.64631043257, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=21.608040201005, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=21.608040201005, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1788722, Length=399, Percent_Identity=29.3233082706767, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786816, Length=357, Percent_Identity=25.4901960784314, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787909, Length=351, Percent_Identity=22.5071225071225, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994472, Length=410, Percent_Identity=22.9268292682927, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71994476, Length=410, Percent_Identity=22.9268292682927, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6320317, Length=366, Percent_Identity=25.1366120218579, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR019881
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.83 [H]

Molecular weight: Translated: 43504; Mature: 43504

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRLSALQPYPFEKLKALVKDVTPSAVHTPISFGIGEPKHPTPALVKDALTAALGGLAN
CCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
YPTTLGSDALRQCIAAWLERRYGLPKVDPATEVIPVNGSREALFSFAQTVIDGSKPGARV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCEE
LCPNPFYQIYEGSALLAGATPLFANSDPARNYAPEFAAITPEEWRNVQLVFVCSPGNPTG
ECCCCCHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCC
AVLTLEDWKQLFALSDEYGFIIASDECYSEIYFDETNPPLGALQAAHQLGRGFDRLVMFS
EEEEHHHHHHHHHCCCCCCEEEECCHHHHHHEECCCCCCHHHHHHHHHHCCCHHHHHHHH
SLSKRSNVPGMRSGFVAGDAKLLKAYLLYRTYHGSAMSPSVQSASIAAWNDETHVRDNRA
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHH
QYVKKFQQVTPMLAEVLDVALPDAAFYLWANVKRTGLSDTEFARQLLAAKNVAVLPGSYL
HHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHCCCCHHHHHHHHHHHCCEEECCCHHH
AREAHGTNPGQDYVRIALVAGVDECLEGARRIVEFCQQR
HHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNPRLSALQPYPFEKLKALVKDVTPSAVHTPISFGIGEPKHPTPALVKDALTAALGGLAN
CCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHC
YPTTLGSDALRQCIAAWLERRYGLPKVDPATEVIPVNGSREALFSFAQTVIDGSKPGARV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCEE
LCPNPFYQIYEGSALLAGATPLFANSDPARNYAPEFAAITPEEWRNVQLVFVCSPGNPTG
ECCCCCHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCCEEEEEEECCCCCCC
AVLTLEDWKQLFALSDEYGFIIASDECYSEIYFDETNPPLGALQAAHQLGRGFDRLVMFS
EEEEHHHHHHHHHCCCCCCEEEECCHHHHHHEECCCCCCHHHHHHHHHHCCCHHHHHHHH
SLSKRSNVPGMRSGFVAGDAKLLKAYLLYRTYHGSAMSPSVQSASIAAWNDETHVRDNRA
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCHHH
QYVKKFQQVTPMLAEVLDVALPDAAFYLWANVKRTGLSDTEFARQLLAAKNVAVLPGSYL
HHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHCCCCHHHHHHHHHHHCCEEECCCHHH
AREAHGTNPGQDYVRIALVAGVDECLEGARRIVEFCQQR
HHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]