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The map label for this gene is dsbB [H]

Identifier: 187928335

GI number: 187928335

Start: 1334749

End: 1335228

Strand: Direct

Name: dsbB [H]

Synonym: Rpic_1246

Alternate gene names: 187928335

Gene position: 1334749-1335228 (Clockwise)

Preceding gene: 187928334

Following gene: 187928336

Centisome position: 33.85

GC content: 65.83

Gene sequence:

>480_bases
ATGCAAGCCAACTCGCGCGCCTTTTTCCTGCTGATTGCCGTGATCTCCTTCGGGGTGGTCGGCTATGCGCTGTACCTGCA
GCACGTCGAGGGGCTGCAGCCGTGCCCGCTGTGCATCCTGCAGCGGTTTGCTTTCCTGGGCATTGGTGTGTTCTCGCTGC
TGGCGGCCCTGTCGTCGGCCACGCGGCTGCTGTGGCACGGGCTGGCGATGCTGTCCGGGCTGGCCGGCCTGTGTGTGGCG
GGGTACCACGTATCGCTGCTGCTGAACCCGAAGGCAACGTGCGGGATCGATCCGATTGAGAACTGGGTCAACGCGCTGCC
GACTGCCAAATGGTTGCCGCAGGTGTTCGAAGCCGATGGCCTGTGCGTCGGGCCGATGCCGCCGGTGCTGGGCCTGTCGG
TGCCGGTGTGGTCGCTGATCTGGCTGGTGATTCTGTCGCTGACGCTGGTGGTGGGGATGATCCGCCGCGAGCGCCGCTAA

Upstream 100 bases:

>100_bases
TTTCACTACGGTATCGCTCGTGCCATTTGAAAATGCGTGTGCCGTTGCGGTGCGATAATCCGCCAACTTTTCTCCACGAC
TCCTCTGTACTGACGCCGCC

Downstream 100 bases:

>100_bases
CCCAGAGCCGCAGATCATGCAACGCGTGCTGGTGAGTGCCTGCCTGCTGGGCCAGCCGGAGCGCTATGACGGCGGCACGG
TCGCCACCGAGGGCGGCATC

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MQANSRAFFLLIAVISFGVVGYALYLQHVEGLQPCPLCILQRFAFLGIGVFSLLAALSSATRLLWHGLAMLSGLAGLCVA
GYHVSLLLNPKATCGIDPIENWVNALPTAKWLPQVFEADGLCVGPMPPVLGLSVPVWSLIWLVILSLTLVVGMIRRERR

Sequences:

>Translated_159_residues
MQANSRAFFLLIAVISFGVVGYALYLQHVEGLQPCPLCILQRFAFLGIGVFSLLAALSSATRLLWHGLAMLSGLAGLCVA
GYHVSLLLNPKATCGIDPIENWVNALPTAKWLPQVFEADGLCVGPMPPVLGLSVPVWSLIWLVILSLTLVVGMIRRERR
>Mature_159_residues
MQANSRAFFLLIAVISFGVVGYALYLQHVEGLQPCPLCILQRFAFLGIGVFSLLAALSSATRLLWHGLAMLSGLAGLCVA
GYHVSLLLNPKATCGIDPIENWVNALPTAKWLPQVFEADGLCVGPMPPVLGLSVPVWSLIWLVILSLTLVVGMIRRERR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein [H]

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family [H]

Homologues:

Organism=Escherichia coli, GI1787433, Length=163, Percent_Identity=30.0613496932515, Blast_Score=69, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003752
- InterPro:   IPR022920 [H]

Pfam domain/function: PF02600 DsbB [H]

EC number: NA

Molecular weight: Translated: 17225; Mature: 17225

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQANSRAFFLLIAVISFGVVGYALYLQHVEGLQPCPLCILQRFAFLGIGVFSLLAALSSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TRLLWHGLAMLSGLAGLCVAGYHVSLLLNPKATCGIDPIENWVNALPTAKWLPQVFEADG
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCC
LCVGPMPPVLGLSVPVWSLIWLVILSLTLVVGMIRRERR
EEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQANSRAFFLLIAVISFGVVGYALYLQHVEGLQPCPLCILQRFAFLGIGVFSLLAALSSA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TRLLWHGLAMLSGLAGLCVAGYHVSLLLNPKATCGIDPIENWVNALPTAKWLPQVFEADG
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCC
LCVGPMPPVLGLSVPVWSLIWLVILSLTLVVGMIRRERR
EEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]