Click here to switch to the map view.

The map label for this gene is arnA [H]

Identifier: 187928284

GI number: 187928284

Start: 1282079

End: 1283020

Strand: Reverse

Name: arnA [H]

Synonym: Rpic_1195

Alternate gene names: 187928284

Gene position: 1283020-1282079 (Counterclockwise)

Preceding gene: 187928285

Following gene: 187928283

Centisome position: 32.54

GC content: 63.48

Gene sequence:

>942_bases
ATGAGTTCCGACATCAAGCGGCGCGCCGTCGTTTTTGCGTATCACAACGTCGGGGTACGCTGCCTGCGCGTGCTGGCCGC
CCGCGGCATCCAGGTCGAACTCGTTGTCACGCACGAAGACAATGCCACCGAGAACATCTGGTTCGGCAGCGTGCGCGCGA
CCGCACAAGAACTGGGTATCCCCTACATCACGCCAGACAATGCAAACGGTGAAGACCTGCACGCCCGGATCGCCGCCATT
GCGCCGGACTTTATCTTTTCATTCTATTACCGGCACATGATCCCGATGCGCCTGTTGAGCCTTGCCAAATTCGGCGCGTT
CAACATGCACGGTTCGCTGCTGCCCAAGTACCGTGGCCGCGTGCCCATCAACTGGGCGGTTCTGCACGGCGAGACCGAGA
CCGGCGCCACCCTGCACGAGATGGTCGAAAAGCCCGATGCCGGTTACATCGTCGACCAGACCATCGTGCCGATCCTGCCG
GACGACACCTCGCACGAAGTGTTCGAGAAGGCCACGGTGGCGGCCGAGCAAACCCTGTGGCGTGCGCTTCCCGCGATGAT
TGCCGGGCACATTCCGCGGCACCCGAACGTGTTGGCCAACGGCAGCTATTTCGGCGGCCGCAAACCCGAAGACGGCCGGA
TCGACTGGTCCAAACCGGCCCAGCAGGTCTACAACCTGATCCGTGCCGTGGCGCCGCCCTACCCTGGCGCCTTTACGGAC
GCCAGCAGCGAGCGCTACGTTGTCGCTCGAGCCCGTCTGGCGCATCAAACCTTTACGAATTTGCCGCCGGGCCTGCACGT
CGTGGATAATGCGATGTTCGGCGTGTGCGGCGATGGGGGAGCCATCGCCATTCACGAGCTCTGGCGCGTCGAGCCCCAAG
CTGCCAGCGGAACGTCTGTCGTGACTGCGCAGCAGCTCGCCAGCCAGCTCGCCCTCTCCTGA

Upstream 100 bases:

>100_bases
AGCGCCCGCGCTATCTGGTGCAGGGCGTGCTGGAGGAAACCTCACATTTGCATGAAGCAGGCGCTGCCGATCTGAAGACG
GGCTCGCAGCGAGGTGTTGC

Downstream 100 bases:

>100_bases
TCTTGAGTTTGCCTTCATGAAAAAAGTACTGATCCTCGGCGTCAACGGCTTCATCGGCCACCACCTGTCCAAGCGCATCC
TGGAGACCACCGATTGGGAG

Product: putative formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSSDIKRRAVVFAYHNVGVRCLRVLAARGIQVELVVTHEDNATENIWFGSVRATAQELGIPYITPDNANGEDLHARIAAI
APDFIFSFYYRHMIPMRLLSLAKFGAFNMHGSLLPKYRGRVPINWAVLHGETETGATLHEMVEKPDAGYIVDQTIVPILP
DDTSHEVFEKATVAAEQTLWRALPAMIAGHIPRHPNVLANGSYFGGRKPEDGRIDWSKPAQQVYNLIRAVAPPYPGAFTD
ASSERYVVARARLAHQTFTNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAASGTSVVTAQQLASQLALS

Sequences:

>Translated_313_residues
MSSDIKRRAVVFAYHNVGVRCLRVLAARGIQVELVVTHEDNATENIWFGSVRATAQELGIPYITPDNANGEDLHARIAAI
APDFIFSFYYRHMIPMRLLSLAKFGAFNMHGSLLPKYRGRVPINWAVLHGETETGATLHEMVEKPDAGYIVDQTIVPILP
DDTSHEVFEKATVAAEQTLWRALPAMIAGHIPRHPNVLANGSYFGGRKPEDGRIDWSKPAQQVYNLIRAVAPPYPGAFTD
ASSERYVVARARLAHQTFTNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAASGTSVVTAQQLASQLALS
>Mature_312_residues
SSDIKRRAVVFAYHNVGVRCLRVLAARGIQVELVVTHEDNATENIWFGSVRATAQELGIPYITPDNANGEDLHARIAAIA
PDFIFSFYYRHMIPMRLLSLAKFGAFNMHGSLLPKYRGRVPINWAVLHGETETGATLHEMVEKPDAGYIVDQTIVPILPD
DTSHEVFEKATVAAEQTLWRALPAMIAGHIPRHPNVLANGSYFGGRKPEDGRIDWSKPAQQVYNLIRAVAPPYPGAFTDA
SSERYVVARARLAHQTFTNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAASGTSVVTAQQLASQLALS

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI21614513, Length=183, Percent_Identity=27.8688524590164, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI238814322, Length=211, Percent_Identity=24.6445497630332, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1788589, Length=305, Percent_Identity=43.2786885245902, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789683, Length=303, Percent_Identity=27.3927392739274, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 34295; Mature: 34164

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSDIKRRAVVFAYHNVGVRCLRVLAARGIQVELVVTHEDNATENIWFGSVRATAQELGI
CCCCCCCEEEEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEECHHHHHHHHCCC
PYITPDNANGEDLHARIAAIAPDFIFSFYYRHMIPMRLLSLAKFGAFNMHGSLLPKYRGR
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCC
VPINWAVLHGETETGATLHEMVEKPDAGYIVDQTIVPILPDDTSHEVFEKATVAAEQTLW
CCEEEEEEECCCCCCHHHHHHHCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHH
RALPAMIAGHIPRHPNVLANGSYFGGRKPEDGRIDWSKPAQQVYNLIRAVAPPYPGAFTD
HHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
ASSERYVVARARLAHQTFTNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAASGTSV
CCCCCEEHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCEEEEEHHHHCCCCCCCCCHH
VTAQQLASQLALS
HHHHHHHHHHCCC
>Mature Secondary Structure 
SSDIKRRAVVFAYHNVGVRCLRVLAARGIQVELVVTHEDNATENIWFGSVRATAQELGI
CCCCCCEEEEEEEHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCEEECHHHHHHHHCCC
PYITPDNANGEDLHARIAAIAPDFIFSFYYRHMIPMRLLSLAKFGAFNMHGSLLPKYRGR
CEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCC
VPINWAVLHGETETGATLHEMVEKPDAGYIVDQTIVPILPDDTSHEVFEKATVAAEQTLW
CCEEEEEEECCCCCCHHHHHHHCCCCCCEEECCCEEEECCCCCHHHHHHHHHHHHHHHHH
RALPAMIAGHIPRHPNVLANGSYFGGRKPEDGRIDWSKPAQQVYNLIRAVAPPYPGAFTD
HHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
ASSERYVVARARLAHQTFTNLPPGLHVVDNAMFGVCGDGGAIAIHELWRVEPQAASGTSV
CCCCCEEHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCEEEEEHHHHCCCCCCCCCHH
VTAQQLASQLALS
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA