Click here to switch to the map view.

The map label for this gene is arnA [H]

Identifier: 187928283

GI number: 187928283

Start: 1281004

End: 1282062

Strand: Reverse

Name: arnA [H]

Synonym: Rpic_1194

Alternate gene names: 187928283

Gene position: 1282062-1281004 (Counterclockwise)

Preceding gene: 187928284

Following gene: 187928282

Centisome position: 32.52

GC content: 59.77

Gene sequence:

>1059_bases
ATGAAAAAAGTACTGATCCTCGGCGTCAACGGCTTCATCGGCCACCACCTGTCCAAGCGCATCCTGGAGACCACCGATTG
GGAGGTCTATGGCATGGACATGCAGACCGAGCGTCTGGGCGACCTGGTCAACCACCCCCGCATGCATTTCTTCGAGGGTG
ACATCACCATCAACAAGGAGTGGGTCGAGTATCACGTGAAGAAGTGCGACGTGATCCTGCCGCTGGTGGCCATCGCCACG
CCGTCGACCTACGTCAAAGACCCGCTGCGCGTGTTCGAACTGGACTTTGAAGCCAACCTGCCGATCGTTCGCTCGGCAGC
CAAGTACGGCAAGCACCTGGTCTTCCCGTCGACCTCCGAGGTCTACGGGATGTGCAGCGATTCGGAATTCGATCCAGAAG
CCTCGCCGCTGGTCTACGGCCCGATCAACAAGCCGCGCTGGATCTACGCATGCTCCAAGCAGTTGATGGACCGCGTGATC
TGGGGTTACGGCATGGAAGGCCTGAACTTCACGCTGTTCCGTCCGTTCAACTGGATCGGCCCGGGCCTCGACTCGATCTA
CACCCCGAAGGAAGGTTCGTCGCGCGTGGTGACGCAATTCCTCGGTCACATCGTGCGCGGCGAGAACATCAAGCTCGTCG
ACGGCGGCAGCCAGAAACGCGCCTTCACGTATATCGATGACGGCATCGACGCACTGGTACGCATCATCGCCAACAAGGAC
GGCGTGGCCTCGGGCAAGATCTACAACATTGGCAACCCGTCAAACAACTACTCGGTGCGCGAGCTGGCCAACATGATGCT
GGAACAAGCCGCCCAGATCGACGAGTACAAGGACACCGCCAAGCAGGTTCAACTGGTGGAAACGACCTCCGGCGCCTACT
ACGGCAACGGCTACCAGGACGTGCAGAACCGCGTGCCGAAGATCGCCAACACCATGGAAGACCTCGGCTGGAAGCCGACC
ACCGTGATGAAGGACGCGCTGGCGAACATCTTCGAAGCGTATCGCACGCACGTGGCTGAAGCCCGCAGCCTGGTCGAAGA
CGGCAACGGCAACAAGTAA

Upstream 100 bases:

>100_bases
CTCTGGCGCGTCGAGCCCCAAGCTGCCAGCGGAACGTCTGTCGTGACTGCGCAGCAGCTCGCCAGCCAGCTCGCCCTCTC
CTGATCTTGAGTTTGCCTTC

Downstream 100 bases:

>100_bases
AAGCCGCATCTCAGTCGCACCTTCCGCGCAGGTTCATGGCCCTCATCGTCCTCAAGATTGACGTCGACACCCTGCGCGGC
ACCCGCGAAGGCGTACCCAA

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MKKVLILGVNGFIGHHLSKRILETTDWEVYGMDMQTERLGDLVNHPRMHFFEGDITINKEWVEYHVKKCDVILPLVAIAT
PSTYVKDPLRVFELDFEANLPIVRSAAKYGKHLVFPSTSEVYGMCSDSEFDPEASPLVYGPINKPRWIYACSKQLMDRVI
WGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENIKLVDGGSQKRAFTYIDDGIDALVRIIANKD
GVASGKIYNIGNPSNNYSVRELANMMLEQAAQIDEYKDTAKQVQLVETTSGAYYGNGYQDVQNRVPKIANTMEDLGWKPT
TVMKDALANIFEAYRTHVAEARSLVEDGNGNK

Sequences:

>Translated_352_residues
MKKVLILGVNGFIGHHLSKRILETTDWEVYGMDMQTERLGDLVNHPRMHFFEGDITINKEWVEYHVKKCDVILPLVAIAT
PSTYVKDPLRVFELDFEANLPIVRSAAKYGKHLVFPSTSEVYGMCSDSEFDPEASPLVYGPINKPRWIYACSKQLMDRVI
WGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENIKLVDGGSQKRAFTYIDDGIDALVRIIANKD
GVASGKIYNIGNPSNNYSVRELANMMLEQAAQIDEYKDTAKQVQLVETTSGAYYGNGYQDVQNRVPKIANTMEDLGWKPT
TVMKDALANIFEAYRTHVAEARSLVEDGNGNK
>Mature_352_residues
MKKVLILGVNGFIGHHLSKRILETTDWEVYGMDMQTERLGDLVNHPRMHFFEGDITINKEWVEYHVKKCDVILPLVAIAT
PSTYVKDPLRVFELDFEANLPIVRSAAKYGKHLVFPSTSEVYGMCSDSEFDPEASPLVYGPINKPRWIYACSKQLMDRVI
WGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENIKLVDGGSQKRAFTYIDDGIDALVRIIANKD
GVASGKIYNIGNPSNNYSVRELANMMLEQAAQIDEYKDTAKQVQLVETTSGAYYGNGYQDVQNRVPKIANTMEDLGWKPT
TVMKDALANIFEAYRTHVAEARSLVEDGNGNK

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=340, Percent_Identity=27.3529411764706, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI7657641, Length=348, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788589, Length=335, Percent_Identity=54.3283582089552, Blast_Score=381, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17539532, Length=347, Percent_Identity=24.207492795389, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 39620; Mature: 39620

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLILGVNGFIGHHLSKRILETTDWEVYGMDMQTERLGDLVNHPRMHFFEGDITINKE
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCEEEEECCEEECHH
WVEYHVKKCDVILPLVAIATPSTYVKDPLRVFELDFEANLPIVRSAAKYGKHLVFPSTSE
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHCCEEECCCCHH
VYGMCSDSEFDPEASPLVYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNWIG
HEEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCC
PGLDSIYTPKEGSSRVVTQFLGHIVRGENIKLVDGGSQKRAFTYIDDGIDALVRIIANKD
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHCCC
GVASGKIYNIGNPSNNYSVRELANMMLEQAAQIDEYKDTAKQVQLVETTSGAYYGNGYQD
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHH
VQNRVPKIANTMEDLGWKPTTVMKDALANIFEAYRTHVAEARSLVEDGNGNK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKKVLILGVNGFIGHHLSKRILETTDWEVYGMDMQTERLGDLVNHPRMHFFEGDITINKE
CCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCEEEEECCEEECHH
WVEYHVKKCDVILPLVAIATPSTYVKDPLRVFELDFEANLPIVRSAAKYGKHLVFPSTSE
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEEECCCCCCHHHHHHHHHCCEEECCCCHH
VYGMCSDSEFDPEASPLVYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNWIG
HEEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCC
PGLDSIYTPKEGSSRVVTQFLGHIVRGENIKLVDGGSQKRAFTYIDDGIDALVRIIANKD
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHCCC
GVASGKIYNIGNPSNNYSVRELANMMLEQAAQIDEYKDTAKQVQLVETTSGAYYGNGYQD
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCHHH
VQNRVPKIANTMEDLGWKPTTVMKDALANIFEAYRTHVAEARSLVEDGNGNK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA