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The map label for this gene is lipA [H]

Identifier: 187928253

GI number: 187928253

Start: 1250816

End: 1252831

Strand: Direct

Name: lipA [H]

Synonym: Rpic_1163

Alternate gene names: 187928253

Gene position: 1250816-1252831 (Clockwise)

Preceding gene: 187928252

Following gene: 187928254

Centisome position: 31.73

GC content: 64.43

Gene sequence:

>2016_bases
ATGCGCGACATGGGCGCGGTTGCCGGGCCTGTGCCTCAGGTCGCCTCATACCTGCGTGGCGTGACGCGGGGCTGGCGCAC
GCTTGGCTCCATCGCGGGCGTTGCCGGTGGTGTATGGGGCGAGCGGCGGGTGGGGCGGGCAGTGCTCCGGCTCAAACGCT
GCATTGATTCGACCACACCGACTTTGCTTCCAGGTCCGATCTGGTCGGAATGCAAGCTCGGGGAGCCGATGCTGTCTTGG
TTCGTGCTGCCCGGGCCAGGTGGCGCGGGTGATCCGATGGAACAGGCCGTGCAGGGATTGCTTGCCAGCGTCGATAGCCT
GGGGACCTCGCCGGAACTGCCTGACCTTATGGCGCGCATGGTCGCCGCCCGTGCGGACCTTGCACGCAATGCCACGCCTG
TTTGTCCACCGGAGTTAATGCAGCCGCATAGTAAGCCGCGCGTGTTACTGATTGACCAGCAATGCGGTTGGGGCGCAACG
AGGGCCGCGTTTGCGCGCATGGTGGCGGCGGCACAGAGCGAGCACCCCGGCGCAGAAATCTGGATCTGGCCCGCTGCCCG
TGGCGCTGCGGGCGGGCTGTCCGGAGCGGGTGATCTGCCTACAGGCACGCGCAGAATTGCTGCGGGTTTCAGTTTTTTCG
CCACGCTGTCACATATTGACCATACATATACGGTGAGCGCGCCCGAAGGCATGCAGGCTCTGTTGGCTGGCATACCTGTG
CGCGTGTTTGGTCGCCCATACTATGCGGGCTGGGGCCTGACAACGGATGATCTTCCGATGCCGGACCGCCCCCACCGCCC
CACACTCGCCGCATTGTTCGACGCGGTCTATCTGCGACTCGCGCGCTATCTTGACCCCGAAACCCATGGTGTTGGCACGC
TGGAACGCTCGCTTGACAGCATTGAGCTGCAGCGCACGGTGCGTGCGCGCTATGCAGATTGCGAGCGAGTGGCGGGGGTG
CGTTTCCAGCTATGGAAGCGGTTTTTCGCCACACCATTCCTGATGGCTGGCGGGAGCAAATTGCGCTGGGCGCGCGTGTC
AGAAAAGATAGAGCACGGGGAGCGTGTGGCGCTGTGGGGGGGCAAGAGCACGGAGGGCATTCCAGCGAGTGCACCCATGT
TGCGCATGGAAGATGGTTTCTTCCACTCCGACGGACTTGGCTCCGACATGAATGCGCCGTGCAGCCAGGTGCTCGATCGG
GAGGGGCTGTATTTCGATGCGCGCACCCCGAACGAACTGACGCATACCCTGAACAGCGCGCAATTCGATGATGCGGAACT
TGCTCGAGCGGCGGCTTTGCGTGAGTTGATAGCTCGCCTTGGCGTCACGAAGTACAACCTCGGCCGGCGCGCGCCGGGCT
GGAACGCACCGGCCGGCAAGACGGTCATCCTCGTGGCTGGCCAGGTGGCCGACGATGCGTCGATCCGCTTCGGCACCGGG
GCACTCGGCACGGCTGAAGCGCTGCTCGAAGCGGTGCGCAAGCGCAATCCAGATGGCTTCATCGTCTACAAGCCGCATCC
AGATGTGTTGTCCGGCAACCGGCAGGGGCTGGTGCATGCCCACGAATTGGCCGACATTGTCGACGCCGAGTCCGACGTGG
TCTCGTTGGTCGATTGCGCCGATGAGGTGCACGTGCTGTCATCGCTCGTTGGATTTGATGCTCTGCTGCGAGGCAAGCGC
GTCTTCACCTATGGGTTGCCGTTCTATGCAGGCTGGGGGCTGACACAAGATGCGCTGGAGCAGCCGTGGCGGCAGCGCAA
GCTGACGCTCGACATGCTGGTGGCTGGTGCGTTGCTGCGCTACCCAATCTATTGGGACTGGCGCACCCGGCTGTTCACCA
CGCCGGAAGCGGTGGTGCGCAAGCTCGGATCAACGGCAGCACGCCCGCTTGGGCGGATTGCGGATGACTGGAAGCGGCCG
CTGCGCAAGGCGTGGCGCTGGAGCCGGAATGCGGCGTGGTACGGATATTGGGCCTGGGCGCAACGTCGGCAGGCGCGCCT
GCGTGGAGTGCTGTAG

Upstream 100 bases:

>100_bases
GCGGCGCGCGAGCCAACTGATCCGCATTGAAGGGTTCCGCGAGCCCACATGGCAGCAGCACTTCGAGGTAGTTGATCAAT
TTATCGAGGAGCTGGCGTAA

Downstream 100 bases:

>100_bases
CGGGGCAGGTGGCGACGAGCGTTGCGATGGGCCAAATGCATTGATTGAGTGAGTGGTAGTCCTTGAGGGAGTTGATATGA
ATATTTACCCCGTCATTCTG

Product: Capsule polysaccharide biosynthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MRDMGAVAGPVPQVASYLRGVTRGWRTLGSIAGVAGGVWGERRVGRAVLRLKRCIDSTTPTLLPGPIWSECKLGEPMLSW
FVLPGPGGAGDPMEQAVQGLLASVDSLGTSPELPDLMARMVAARADLARNATPVCPPELMQPHSKPRVLLIDQQCGWGAT
RAAFARMVAAAQSEHPGAEIWIWPAARGAAGGLSGAGDLPTGTRRIAAGFSFFATLSHIDHTYTVSAPEGMQALLAGIPV
RVFGRPYYAGWGLTTDDLPMPDRPHRPTLAALFDAVYLRLARYLDPETHGVGTLERSLDSIELQRTVRARYADCERVAGV
RFQLWKRFFATPFLMAGGSKLRWARVSEKIEHGERVALWGGKSTEGIPASAPMLRMEDGFFHSDGLGSDMNAPCSQVLDR
EGLYFDARTPNELTHTLNSAQFDDAELARAAALRELIARLGVTKYNLGRRAPGWNAPAGKTVILVAGQVADDASIRFGTG
ALGTAEALLEAVRKRNPDGFIVYKPHPDVLSGNRQGLVHAHELADIVDAESDVVSLVDCADEVHVLSSLVGFDALLRGKR
VFTYGLPFYAGWGLTQDALEQPWRQRKLTLDMLVAGALLRYPIYWDWRTRLFTTPEAVVRKLGSTAARPLGRIADDWKRP
LRKAWRWSRNAAWYGYWAWAQRRQARLRGVL

Sequences:

>Translated_671_residues
MRDMGAVAGPVPQVASYLRGVTRGWRTLGSIAGVAGGVWGERRVGRAVLRLKRCIDSTTPTLLPGPIWSECKLGEPMLSW
FVLPGPGGAGDPMEQAVQGLLASVDSLGTSPELPDLMARMVAARADLARNATPVCPPELMQPHSKPRVLLIDQQCGWGAT
RAAFARMVAAAQSEHPGAEIWIWPAARGAAGGLSGAGDLPTGTRRIAAGFSFFATLSHIDHTYTVSAPEGMQALLAGIPV
RVFGRPYYAGWGLTTDDLPMPDRPHRPTLAALFDAVYLRLARYLDPETHGVGTLERSLDSIELQRTVRARYADCERVAGV
RFQLWKRFFATPFLMAGGSKLRWARVSEKIEHGERVALWGGKSTEGIPASAPMLRMEDGFFHSDGLGSDMNAPCSQVLDR
EGLYFDARTPNELTHTLNSAQFDDAELARAAALRELIARLGVTKYNLGRRAPGWNAPAGKTVILVAGQVADDASIRFGTG
ALGTAEALLEAVRKRNPDGFIVYKPHPDVLSGNRQGLVHAHELADIVDAESDVVSLVDCADEVHVLSSLVGFDALLRGKR
VFTYGLPFYAGWGLTQDALEQPWRQRKLTLDMLVAGALLRYPIYWDWRTRLFTTPEAVVRKLGSTAARPLGRIADDWKRP
LRKAWRWSRNAAWYGYWAWAQRRQARLRGVL
>Mature_671_residues
MRDMGAVAGPVPQVASYLRGVTRGWRTLGSIAGVAGGVWGERRVGRAVLRLKRCIDSTTPTLLPGPIWSECKLGEPMLSW
FVLPGPGGAGDPMEQAVQGLLASVDSLGTSPELPDLMARMVAARADLARNATPVCPPELMQPHSKPRVLLIDQQCGWGAT
RAAFARMVAAAQSEHPGAEIWIWPAARGAAGGLSGAGDLPTGTRRIAAGFSFFATLSHIDHTYTVSAPEGMQALLAGIPV
RVFGRPYYAGWGLTTDDLPMPDRPHRPTLAALFDAVYLRLARYLDPETHGVGTLERSLDSIELQRTVRARYADCERVAGV
RFQLWKRFFATPFLMAGGSKLRWARVSEKIEHGERVALWGGKSTEGIPASAPMLRMEDGFFHSDGLGSDMNAPCSQVLDR
EGLYFDARTPNELTHTLNSAQFDDAELARAAALRELIARLGVTKYNLGRRAPGWNAPAGKTVILVAGQVADDASIRFGTG
ALGTAEALLEAVRKRNPDGFIVYKPHPDVLSGNRQGLVHAHELADIVDAESDVVSLVDCADEVHVLSSLVGFDALLRGKR
VFTYGLPFYAGWGLTQDALEQPWRQRKLTLDMLVAGALLRYPIYWDWRTRLFTTPEAVVRKLGSTAARPLGRIADDWKRP
LRKAWRWSRNAAWYGYWAWAQRRQARLRGVL

Specific function: Involved in the phospholipid modification of the capsular polysaccharide, a strong requirement for its translocation to the cell surface [H]

COG id: COG3563

COG function: function code M; Capsule polysaccharide export protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007833 [H]

Pfam domain/function: PF05159 Capsule_synth [H]

EC number: NA

Molecular weight: Translated: 73436; Mature: 73436

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDMGAVAGPVPQVASYLRGVTRGWRTLGSIAGVAGGVWGERRVGRAVLRLKRCIDSTTP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
TLLPGPIWSECKLGEPMLSWFVLPGPGGAGDPMEQAVQGLLASVDSLGTSPELPDLMARM
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VAARADLARNATPVCPPELMQPHSKPRVLLIDQQCGWGATRAAFARMVAAAQSEHPGAEI
HHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEE
WIWPAARGAAGGLSGAGDLPTGTRRIAAGFSFFATLSHIDHTYTVSAPEGMQALLAGIPV
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCE
RVFGRPYYAGWGLTTDDLPMPDRPHRPTLAALFDAVYLRLARYLDPETHGVGTLERSLDS
EECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
IELQRTVRARYADCERVAGVRFQLWKRFFATPFLMAGGSKLRWARVSEKIEHGERVALWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCEEHHHHHHHHHCCCEEEEEC
GKSTEGIPASAPMLRMEDGFFHSDGLGSDMNAPCSQVLDREGLYFDARTPNELTHTLNSA
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHCCCCCEECCCCCHHHHHHHCCC
QFDDAELARAAALRELIARLGVTKYNLGRRAPGWNAPAGKTVILVAGQVADDASIRFGTG
CCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECCC
ALGTAEALLEAVRKRNPDGFIVYKPHPDVLSGNRQGLVHAHELADIVDAESDVVSLVDCA
CCHHHHHHHHHHHHCCCCCEEEECCCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
DEVHVLSSLVGFDALLRGKRVFTYGLPFYAGWGLTQDALEQPWRQRKLTLDMLVAGALLR
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHHH
YPIYWDWRTRLFTTPEAVVRKLGSTAARPLGRIADDWKRPLRKAWRWSRNAAWYGYWAWA
CCCEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHH
QRRQARLRGVL
HHHHHHHCCCC
>Mature Secondary Structure
MRDMGAVAGPVPQVASYLRGVTRGWRTLGSIAGVAGGVWGERRVGRAVLRLKRCIDSTTP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
TLLPGPIWSECKLGEPMLSWFVLPGPGGAGDPMEQAVQGLLASVDSLGTSPELPDLMARM
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
VAARADLARNATPVCPPELMQPHSKPRVLLIDQQCGWGATRAAFARMVAAAQSEHPGAEI
HHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEE
WIWPAARGAAGGLSGAGDLPTGTRRIAAGFSFFATLSHIDHTYTVSAPEGMQALLAGIPV
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCE
RVFGRPYYAGWGLTTDDLPMPDRPHRPTLAALFDAVYLRLARYLDPETHGVGTLERSLDS
EECCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
IELQRTVRARYADCERVAGVRFQLWKRFFATPFLMAGGSKLRWARVSEKIEHGERVALWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCCCCEEHHHHHHHHHCCCEEEEEC
GKSTEGIPASAPMLRMEDGFFHSDGLGSDMNAPCSQVLDREGLYFDARTPNELTHTLNSA
CCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHCCCCCEECCCCCHHHHHHHCCC
QFDDAELARAAALRELIARLGVTKYNLGRRAPGWNAPAGKTVILVAGQVADDASIRFGTG
CCCHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCCEEEEEECCCCCCCCEEECCC
ALGTAEALLEAVRKRNPDGFIVYKPHPDVLSGNRQGLVHAHELADIVDAESDVVSLVDCA
CCHHHHHHHHHHHHCCCCCEEEECCCCCHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
DEVHVLSSLVGFDALLRGKRVFTYGLPFYAGWGLTQDALEQPWRQRKLTLDMLVAGALLR
HHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCCCCHHHHHCHHHHHHHHHHHHHHHHHHH
YPIYWDWRTRLFTTPEAVVRKLGSTAARPLGRIADDWKRPLRKAWRWSRNAAWYGYWAWA
CCCEEECCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHH
QRRQARLRGVL
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]