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The map label for this gene is xanB [H]

Identifier: 187928254

GI number: 187928254

Start: 1252908

End: 1254332

Strand: Direct

Name: xanB [H]

Synonym: Rpic_1164

Alternate gene names: 187928254

Gene position: 1252908-1254332 (Clockwise)

Preceding gene: 187928253

Following gene: 187928256

Centisome position: 31.78

GC content: 61.12

Gene sequence:

>1425_bases
ATGAATATTTACCCCGTCATTCTGTGTGGCGGAAGCGGTACCCGTCTCTGGCCAATGTCGCGCGGCGGCTATCCGAAACA
GTATCTGAAGCTCGTCGGCGAACACACGCTGGTGCAACAGACGGCGCTGCGCCTGCGCGGTATCGGCAATGTGGCCGCCC
CGATCGTGATCACCAATGAGGAGCAGCGCTTTCTGGTGGCCGAGCAACTGCGCAGCGTCGACGTGAAACCGTCGGCAATC
GTGCTTGAGCCGGTCGGCCGCGATACGGCGCCAGCCGTAGCCGTGGCGGCCCTGCTTGCATCGCAGGCAACGCCCGATGC
GCTGCTGCTGGTACTGCCGTCGGATCACGTGATCGAGGACGACGTGGTGTTCGGCAAGCTCGCCACGGTTGCAGCCAGTG
TCGCCAAGGATAACTTCTTGGTCACTTTTGGCATCGAGCCCACCGAGCCGCATACGGGTTACGGCTACATCCGCGGTGGC
GAAGCGCTGGTTGCAGTCGATGGCACGTACCGGGTGGAGCGTTTTGTGGAAAAGCCGGACGCGGTGACCGCCGCCCGCTT
GCTGGAAGAGGGTGGGTACTACTGGAACAGCGGCATGTTCATGCTGAAGGCGGCCGCTTACCTGGACGAACTCCGCCAGC
ATGCGCCCGAGATTCTCCGTCAAGCAGAACTGGCACTGAACGCCGCCAAGCGCGACGCTGATTTCGTGCGGCTCGATGCA
GAGGCCTTCGGCGCCAGCCCCAAGCTGTCGATCGACTACGCCGTCATGGAAAAAACGGCACATGCTGCCGTTGTGACGGC
GGCTGGCCTGGGCTGGAACGACATCGGTTCGTGGACGGCTCTTGCCGAGATCGCCAACGTCGACGACAACGGCAATGCGT
TGTTTGGGGACGTGCTGGTCGAGGACGCGAGGAACACATACGTGCGGGCCGAGCACCGCATGGTGGCGGCGGTGGGCGTC
AACGACCTGGTGATTGTGGAAACCGCCGATGCGATTCTGGTGTCGCACCGTGACAGAGCGCAGGACGTCAAGAAGATCGT
CGAGCGTCTGAACAGCTCGGGCCGTCACGAGTCGGTCACGCACCGCAAGGTGTTTCGCCCTTGGGGTTCATATGAGGGCA
TTGACCAAGGCGAGCGCTTCCAGGTCAAGCGCATCATCGTCAATCCGGGCTCGTCGCTCAGTCTGCAAATGCATCACCAT
CGTGCAGAACATTGGATCGTGGTGTGCGGCACCGCCAAGGTATTCAACGGTGATCAGGTGATGCTGCTGTCGGAAAACCA
GTCAACGTATATACCGCTAGGCGTGACGCATCGCCTGGAAAACCCGGGCAAGATTCCGCTTGAGCTGATTGAAGTGCAAT
CCGGATCCTACCTTGGCGAGGACGATATTGTTCGCTTCCAGGATCACTACGGGCGCGTTGCTTAG

Upstream 100 bases:

>100_bases
GCGCGCCTGCGTGGAGTGCTGTAGCGGGGCAGGTGGCGACGAGCGTTGCGATGGGCCAAATGCATTGATTGAGTGAGTGG
TAGTCCTTGAGGGAGTTGAT

Downstream 100 bases:

>100_bases
GCGAGCTCACGACTGCAAAGACTACCTCGCGCACGCGCCCACGGGCGCATGCCGAGGGCGGTGAGGCTACTGTTGGTCTG
GTGGTTTGGTTTAGTTGGGG

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MNIYPVILCGGSGTRLWPMSRGGYPKQYLKLVGEHTLVQQTALRLRGIGNVAAPIVITNEEQRFLVAEQLRSVDVKPSAI
VLEPVGRDTAPAVAVAALLASQATPDALLLVLPSDHVIEDDVVFGKLATVAASVAKDNFLVTFGIEPTEPHTGYGYIRGG
EALVAVDGTYRVERFVEKPDAVTAARLLEEGGYYWNSGMFMLKAAAYLDELRQHAPEILRQAELALNAAKRDADFVRLDA
EAFGASPKLSIDYAVMEKTAHAAVVTAAGLGWNDIGSWTALAEIANVDDNGNALFGDVLVEDARNTYVRAEHRMVAAVGV
NDLVIVETADAILVSHRDRAQDVKKIVERLNSSGRHESVTHRKVFRPWGSYEGIDQGERFQVKRIIVNPGSSLSLQMHHH
RAEHWIVVCGTAKVFNGDQVMLLSENQSTYIPLGVTHRLENPGKIPLELIEVQSGSYLGEDDIVRFQDHYGRVA

Sequences:

>Translated_474_residues
MNIYPVILCGGSGTRLWPMSRGGYPKQYLKLVGEHTLVQQTALRLRGIGNVAAPIVITNEEQRFLVAEQLRSVDVKPSAI
VLEPVGRDTAPAVAVAALLASQATPDALLLVLPSDHVIEDDVVFGKLATVAASVAKDNFLVTFGIEPTEPHTGYGYIRGG
EALVAVDGTYRVERFVEKPDAVTAARLLEEGGYYWNSGMFMLKAAAYLDELRQHAPEILRQAELALNAAKRDADFVRLDA
EAFGASPKLSIDYAVMEKTAHAAVVTAAGLGWNDIGSWTALAEIANVDDNGNALFGDVLVEDARNTYVRAEHRMVAAVGV
NDLVIVETADAILVSHRDRAQDVKKIVERLNSSGRHESVTHRKVFRPWGSYEGIDQGERFQVKRIIVNPGSSLSLQMHHH
RAEHWIVVCGTAKVFNGDQVMLLSENQSTYIPLGVTHRLENPGKIPLELIEVQSGSYLGEDDIVRFQDHYGRVA
>Mature_474_residues
MNIYPVILCGGSGTRLWPMSRGGYPKQYLKLVGEHTLVQQTALRLRGIGNVAAPIVITNEEQRFLVAEQLRSVDVKPSAI
VLEPVGRDTAPAVAVAALLASQATPDALLLVLPSDHVIEDDVVFGKLATVAASVAKDNFLVTFGIEPTEPHTGYGYIRGG
EALVAVDGTYRVERFVEKPDAVTAARLLEEGGYYWNSGMFMLKAAAYLDELRQHAPEILRQAELALNAAKRDADFVRLDA
EAFGASPKLSIDYAVMEKTAHAAVVTAAGLGWNDIGSWTALAEIANVDDNGNALFGDVLVEDARNTYVRAEHRMVAAVGV
NDLVIVETADAILVSHRDRAQDVKKIVERLNSSGRHESVTHRKVFRPWGSYEGIDQGERFQVKRIIVNPGSSLSLQMHHH
RAEHWIVVCGTAKVFNGDQVMLLSENQSTYIPLGVTHRLENPGKIPLELIEVQSGSYLGEDDIVRFQDHYGRVA

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=476, Percent_Identity=53.9915966386555, Blast_Score=499, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51831; Mature: 51831

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIYPVILCGGSGTRLWPMSRGGYPKQYLKLVGEHTLVQQTALRLRGIGNVAAPIVITNE
CCEEEEEEECCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEECCEEEECC
EQRFLVAEQLRSVDVKPSAIVLEPVGRDTAPAVAVAALLASQATPDALLLVLPSDHVIED
CCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCEECC
DVVFGKLATVAASVAKDNFLVTFGIEPTEPHTGYGYIRGGEALVAVDGTYRVERFVEKPD
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCCEEEEECCCHHHHHHHCCCC
AVTAARLLEEGGYYWNSGMFMLKAAAYLDELRQHAPEILRQAELALNAAKRDADFVRLDA
HHHHHHHHHHCCCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
EAFGASPKLSIDYAVMEKTAHAAVVTAAGLGWNDIGSWTALAEIANVDDNGNALFGDVLV
HHHCCCCCCEEEHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCEEEHHHHH
EDARNTYVRAEHRMVAAVGVNDLVIVETADAILVSHRDRAQDVKKIVERLNSSGRHESVT
HCCCCCEEEECCEEEEEECCCCEEEEEECCEEEECCCHHHHHHHHHHHHHCCCCCCCCHH
HRKVFRPWGSYEGIDQGERFQVKRIIVNPGSSLSLQMHHHRAEHWIVVCGTAKVFNGDQV
HHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCEEEEEEECEEEECCCEE
MLLSENQSTYIPLGVTHRLENPGKIPLELIEVQSGSYLGEDDIVRFQDHYGRVA
EEEECCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEHHHCCCCC
>Mature Secondary Structure
MNIYPVILCGGSGTRLWPMSRGGYPKQYLKLVGEHTLVQQTALRLRGIGNVAAPIVITNE
CCEEEEEEECCCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCEECCEEEECC
EQRFLVAEQLRSVDVKPSAIVLEPVGRDTAPAVAVAALLASQATPDALLLVLPSDHVIED
CCHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCEECC
DVVFGKLATVAASVAKDNFLVTFGIEPTEPHTGYGYIRGGEALVAVDGTYRVERFVEKPD
CHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECCCEEEEECCCHHHHHHHCCCC
AVTAARLLEEGGYYWNSGMFMLKAAAYLDELRQHAPEILRQAELALNAAKRDADFVRLDA
HHHHHHHHHHCCCEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
EAFGASPKLSIDYAVMEKTAHAAVVTAAGLGWNDIGSWTALAEIANVDDNGNALFGDVLV
HHHCCCCCCEEEHHHHHHHHCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCEEEHHHHH
EDARNTYVRAEHRMVAAVGVNDLVIVETADAILVSHRDRAQDVKKIVERLNSSGRHESVT
HCCCCCEEEECCEEEEEECCCCEEEEEECCEEEECCCHHHHHHHHHHHHHCCCCCCCCHH
HRKVFRPWGSYEGIDQGERFQVKRIIVNPGSSLSLQMHHHRAEHWIVVCGTAKVFNGDQV
HHHHHCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCEEEEEEECEEEECCCEE
MLLSENQSTYIPLGVTHRLENPGKIPLELIEVQSGSYLGEDDIVRFQDHYGRVA
EEEECCCCEEEEEEEEECCCCCCCCCEEEEEECCCCCCCCCCEEEEHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]