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The map label for this gene is catB2 [H]

Identifier: 187928245

GI number: 187928245

Start: 1237327

End: 1237986

Strand: Reverse

Name: catB2 [H]

Synonym: Rpic_1155

Alternate gene names: 187928245

Gene position: 1237986-1237327 (Counterclockwise)

Preceding gene: 187928246

Following gene: 187928240

Centisome position: 31.4

GC content: 49.7

Gene sequence:

>660_bases
ATGCTCTTCGCCGAGCTCCTGCGTTTGCAAGGTCACACTGAGCCACTCAGCCAACGGAGCCGACTTTATATGATCAGTGA
TTTAGTTTCAGAAGATATCAGGGTTTCGATAGGTAAAGGCACCTATGCGTCCTCTCCGCCAATTATCCGCCCACATCATG
CGAATAATCGAATAGTCATTGGCAACTATTGCTGCCTCGCGCACGACGTGACTATTTTTGCCGGCGGCAACCATCCCATG
GGCTATCTGACAATGCATCCTCTGAAGCTCTATTTGGGTAAGGGATCATTTGAGGACTGGTCCGCCGATTGTGGCGATGA
CGCTGAAACAACGACAATTGGGAACGATGTATGGATCGGTCATGGTGCAACAATTTTGTCCGGAGTTAAAATTGGAGATG
GCGCAGTCATCGGGGCCCGTACTGTTGTCGCGAGTGATGTGCCGCCTTACGCCATTGTTGCAGGTAACCCGGCAAAATTA
ATCAGAAAGCGCTTTAGCGAGCCGCAGATTGAACAACTATTGAAACTCGGCTGGTGGAATTGGCCACGAGAACACATTGA
AGAAGCTGCAGAATATCTGTGTTCTGGCGATCTTGATGCACTCTTGGCCTTTGCAGGGGAAAAGCGAGGAGTATCAAGTC
CTTGTTCATCCGTACACTAG

Upstream 100 bases:

>100_bases
GTACGCTGGAGGTGTGCCGGCAGTTCGCGTGATGGGTGGCGCGATGATGTACCGTGCGGGCGAGGTGTTATCGAACCGCC
AGTGAAGTCCGTCTTATCTC

Downstream 100 bases:

>100_bases
TCTGCAACCTGACATTCATGTGCACGTTGGCGGCGCAAACCTGACCAACGACGGCGAGCTTATGCAGTGATGCAACGCAT
GTCGCTGCAGCCGAGAGAGA

Product: transferase hexapeptide repeat containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MLFAELLRLQGHTEPLSQRSRLYMISDLVSEDIRVSIGKGTYASSPPIIRPHHANNRIVIGNYCCLAHDVTIFAGGNHPM
GYLTMHPLKLYLGKGSFEDWSADCGDDAETTTIGNDVWIGHGATILSGVKIGDGAVIGARTVVASDVPPYAIVAGNPAKL
IRKRFSEPQIEQLLKLGWWNWPREHIEEAAEYLCSGDLDALLAFAGEKRGVSSPCSSVH

Sequences:

>Translated_219_residues
MLFAELLRLQGHTEPLSQRSRLYMISDLVSEDIRVSIGKGTYASSPPIIRPHHANNRIVIGNYCCLAHDVTIFAGGNHPM
GYLTMHPLKLYLGKGSFEDWSADCGDDAETTTIGNDVWIGHGATILSGVKIGDGAVIGARTVVASDVPPYAIVAGNPAKL
IRKRFSEPQIEQLLKLGWWNWPREHIEEAAEYLCSGDLDALLAFAGEKRGVSSPCSSVH
>Mature_219_residues
MLFAELLRLQGHTEPLSQRSRLYMISDLVSEDIRVSIGKGTYASSPPIIRPHHANNRIVIGNYCCLAHDVTIFAGGNHPM
GYLTMHPLKLYLGKGSFEDWSADCGDDAETTTIGNDVWIGHGATILSGVKIGDGAVIGARTVVASDVPPYAIVAGNPAKL
IRKRFSEPQIEQLLKLGWWNWPREHIEEAAEYLCSGDLDALLAFAGEKRGVSSPCSSVH

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1788367, Length=108, Percent_Identity=32.4074074074074, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786664, Length=164, Percent_Identity=29.2682926829268, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786537, Length=129, Percent_Identity=34.1085271317829, Blast_Score=60, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=107, Percent_Identity=36.4485981308411, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 23837; Mature: 23837

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFAELLRLQGHTEPLSQRSRLYMISDLVSEDIRVSIGKGTYASSPPIIRPHHANNRIVI
CHHHHHHHHCCCCCCHHHHHHEEHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCEEEE
GNYCCLAHDVTIFAGGNHPMGYLTMHPLKLYLGKGSFEDWSADCGDDAETTTIGNDVWIG
ECEEEEEECEEEEECCCCCEEEEEECEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEC
HGATILSGVKIGDGAVIGARTVVASDVPPYAIVAGNPAKLIRKRFSEPQIEQLLKLGWWN
CCHHHHCCEEECCCEEECCCEEEECCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHCCCC
WPREHIEEAAEYLCSGDLDALLAFAGEKRGVSSPCSSVH
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MLFAELLRLQGHTEPLSQRSRLYMISDLVSEDIRVSIGKGTYASSPPIIRPHHANNRIVI
CHHHHHHHHCCCCCCHHHHHHEEHHHHHHCCCEEEEECCCCCCCCCCEECCCCCCCEEEE
GNYCCLAHDVTIFAGGNHPMGYLTMHPLKLYLGKGSFEDWSADCGDDAETTTIGNDVWIG
ECEEEEEECEEEEECCCCCEEEEEECEEEEEECCCCCCCCCCCCCCCCCEEECCCEEEEC
HGATILSGVKIGDGAVIGARTVVASDVPPYAIVAGNPAKLIRKRFSEPQIEQLLKLGWWN
CCHHHHCCEEECCCEEECCCEEEECCCCCEEEEECCHHHHHHHHCCCHHHHHHHHHCCCC
WPREHIEEAAEYLCSGDLDALLAFAGEKRGVSSPCSSVH
CCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1314803 [H]