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The map label for this gene is hflC [H]

Identifier: 187928160

GI number: 187928160

Start: 1134533

End: 1135447

Strand: Direct

Name: hflC [H]

Synonym: Rpic_1067

Alternate gene names: 187928160

Gene position: 1134533-1135447 (Clockwise)

Preceding gene: 187928159

Following gene: 187928161

Centisome position: 28.78

GC content: 61.2

Gene sequence:

>915_bases
ATGAATCGTCTGATTTCTGCCTTCGTGGCGCTGGTCATTGCCCTGGCGGTGTTCTCGTCGGTGGTGTTCGTGGTGGATCA
GCGGCAGTACGCCGTGGTATTCGCCTTTGGGGAGATCAAGCAGGTCATCAAGGAGCCGGGGCTGCATTTCAAGCTTCCGC
CCCCGCTGCAGAACGTGGTGTTCATGGATAAGCGCCTGCAGACCATCGATGTGGCCGGCGCCGATCGTTTCATTACGGCA
GAGAAAAAGAACCTGCTGGTCGACTGGTTCGTGAAGTGGCGCGTGTCCGATCCGCGTCTGTTCTACGTGAGCTTCAAGGG
CGATAGCCGCCTTGCGCAGGACAGCATGACGCAGAAGATCAACTCCATCGCCCGAGATGAGTTTGCGCGCCGCACTGTTT
CCGACGTGGTATCGACGGATCGCGAAGCTGTGATGCAGAGCATCCTCAAGGGCGTACAGGAGTACGGCAAGTCGGTCGGC
GTGGACATCATCGACGTGCGCCTGAAGCGGGTGGATCTGCTGGCCAGCGTGACCGAATCGGTCTACCGTCGCATGGAAGC
CGAGCGCAAGCGCGTGGCCAACGAGCTGCGTTCGACGGGGGCTGCTGAGGGCGAAAAAATCCGCGCCGATGCCGACCGTC
AGCGCGAAGTCGTCCTGGCCGATGCCTACCGAGATGCGCAGAAGATCAAGGGGGAAGGCGATGCCCGCGCCGCTGACATT
TATGCCGAGGCGTTTGGCCGTGATCCGCAGTTCGCCGCATTCTGGCGCTCCATGGAGGCGTATCGCGCATCGTTCCGAGA
TCGGAAGGACGTGATGGTGCTGCAGCCGAACAACGATTTCTTCAAATACATGCGCAGCCCGAACGGCGGCAGCTCGTCAG
CAGCGCCGGCTGCCCAGACGGGGCGACATCGCTAG

Upstream 100 bases:

>100_bases
GCCCACTCCCTCCAATCCGTCACCGGCCAATGACGCAGATTCGCGCTCGCGCGAAGCGCTGCGCAACCGTGACCGCGATT
CGCGCTAACAGGAGGGCACT

Downstream 100 bases:

>100_bases
TACAATGCTTCGCTGATTATTTGAGGCGGACAGACCCCGGCTTGCCGGGGTTTTGTTCGTTTGCCAACCGCATCCCATGG
AAGAGTCACTCCCCAACGTT

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MNRLISAFVALVIALAVFSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVVFMDKRLQTIDVAGADRFITA
EKKNLLVDWFVKWRVSDPRLFYVSFKGDSRLAQDSMTQKINSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGKSVG
VDIIDVRLKRVDLLASVTESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYRDAQKIKGEGDARAADI
YAEAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPNNDFFKYMRSPNGGSSSAAPAAQTGRHR

Sequences:

>Translated_304_residues
MNRLISAFVALVIALAVFSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVVFMDKRLQTIDVAGADRFITA
EKKNLLVDWFVKWRVSDPRLFYVSFKGDSRLAQDSMTQKINSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGKSVG
VDIIDVRLKRVDLLASVTESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYRDAQKIKGEGDARAADI
YAEAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPNNDFFKYMRSPNGGSSSAAPAAQTGRHR
>Mature_304_residues
MNRLISAFVALVIALAVFSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVVFMDKRLQTIDVAGADRFITA
EKKNLLVDWFVKWRVSDPRLFYVSFKGDSRLAQDSMTQKINSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGKSVG
VDIIDVRLKRVDLLASVTESVYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYRDAQKIKGEGDARAADI
YAEAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPNNDFFKYMRSPNGGSSSAAPAAQTGRHR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=316, Percent_Identity=36.3924050632911, Blast_Score=195, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 34358; Mature: 34358

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLISAFVALVIALAVFSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCEEECCCCHHHHH
FMDKRLQTIDVAGADRFITAEKKNLLVDWFVKWRVSDPRLFYVSFKGDSRLAQDSMTQKI
HHHHHHHEEEECCCCCEEECCCCCCEEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHH
NSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGKSVGVDIIDVRLKRVDLLASVTES
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYRDAQKIKGEGDARAADI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHH
YAEAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPNNDFFKYMRSPNGGSSSAAPAAQT
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCC
GRHR
CCCC
>Mature Secondary Structure
MNRLISAFVALVIALAVFSSVVFVVDQRQYAVVFAFGEIKQVIKEPGLHFKLPPPLQNVV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHCCCCEEECCCCHHHHH
FMDKRLQTIDVAGADRFITAEKKNLLVDWFVKWRVSDPRLFYVSFKGDSRLAQDSMTQKI
HHHHHHHEEEECCCCCEEECCCCCCEEEEEEEEEECCCEEEEEEECCCCHHHHHHHHHHH
NSIARDEFARRTVSDVVSTDREAVMQSILKGVQEYGKSVGVDIIDVRLKRVDLLASVTES
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VYRRMEAERKRVANELRSTGAAEGEKIRADADRQREVVLADAYRDAQKIKGEGDARAADI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHH
YAEAFGRDPQFAAFWRSMEAYRASFRDRKDVMVLQPNNDFFKYMRSPNGGSSSAAPAAQT
HHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCCCCCCCCCCC
GRHR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]