Click here to switch to the map view.

The map label for this gene is hflK [H]

Identifier: 187928159

GI number: 187928159

Start: 1133087

End: 1134520

Strand: Direct

Name: hflK [H]

Synonym: Rpic_1066

Alternate gene names: 187928159

Gene position: 1133087-1134520 (Clockwise)

Preceding gene: 187928158

Following gene: 187928160

Centisome position: 28.74

GC content: 62.2

Gene sequence:

>1434_bases
ATGGCCCGCTACTTCTTCGCAGTCAGACAATCAGGACAAGCCCGACCGCTCATGCCCGAGATTTCGACCCAGTCTTCTTC
CATGGCCTCGCCGCGTCCGGCGCGAGGTTTGTGGCACCGCTTGCGTGTGCTGCTTTCGCTGAACGATCCGCGCTGGGGTC
GCGGCGATGACAACAACAACGCCGAGCGCGAAGGCAACAAAGACGAACCAAAGCGTCAAAGCAAACCGCCTCAGGATGGC
CCCCCCGACCTTGACGAGTTGTGGCGCGACTTCAATCGCCGCCTGAACAACCTGTTCGGCCGCAAGGACAGCGGTAACGG
TAGCGACGGCCCCACGCCGCTGCGTCCCGGTAACGGCCGTGGCGGCTCGGGCCTGGGCATCGGCGTGCTGCTGGCGGTGC
TCGTTGGCCTGTGGCTAGCCAGCGGTTTCTTTATCGTGCAGGAAGGCCAGACGGGCGTGATCCTGCAGTTCGGCCGTTTC
AAGTACCTGGCAACGCCGGGTATTAACTGGCGTCTGCCGTATCCGGTCGAATCGCACGAAATCGTGAACCTGTCGGGTGT
GCGCACGCTTGAAATCGGTCGGACTACCCAGATCAAGGACACGAACCTGAAAGATTCCTCGATGCTCACGCAGGACGAGA
ACATCGTCGACGTGCGCTTCTCGGTCCAGTACAACATTGCCAATCCCGTCGACTACCTGTTCTACAACCGTACGGACCGT
GGCGGCGATGAAGAACTGGTGACGCAGGCGGCCGAGACGTCGGTGCGCGAGATCGTCGGTCGCAACAAGATGGATGCGGT
TCTGTACGAAGGTCGTGATGCTGTGGGCCGTAATCTCGCGGAATCGATTCAACGCATCTTGTCGGCGTACAAGACCGGGA
TTCGAATCCTCAGCGTGAACGTGCAGAGCGTGCAGCCGCCCGAGCAGGTGCAGGCCGCGTTCGATGACGTGACCAAGGCT
GGCCAGGACCGCGAGCGTGCCATTTCTGAAGGTCAGGCTTACGCCAATGACGTGGTGCCGCGCGCCAAGGGCACGGCCGC
GCGTCTGGGCGAAGAGGCCCAAGGCTACAAGGCACGCGTCACTGCGCGTGCGGAAGGTGATGCGGCGCGCTTTGCGTCGG
TGCAACGTGAGTACGCGAAAGCGCCGCAGGTCACGCGCGACCGTATCTATCTGGAAACCATGCAAGACATTTACGCCAAT
TCGACGAAAGTCTTGGTCGACCAGAGCAATGGCAGCCTCTTGTATTTGCCGCTGGACAAGCTGATCGCGCAAACGCAGGG
CGACACATCGCGCCCGGCTCCCGCGCCGGGTGCTTCTGCGCAGGACAGCGGTTCTGCGCAGGGCGTGCCCACTCCCTCCA
ATCCGTCACCGGCCAATGACGCAGATTCGCGCTCGCGCGAAGCGCTGCGCAACCGTGACCGCGATTCGCGCTAA

Upstream 100 bases:

>100_bases
GACACCCGACGTGATTCGCCGCCGGCCCACCGTGACGAACTGTCGCAAAGCTTGCCGAGCAGCGGTTCTTCCGCCAAAGG
TGACGAAGAGGGCTGATAGA

Downstream 100 bases:

>100_bases
CAGGAGGGCACTATGAATCGTCTGATTTCTGCCTTCGTGGCGCTGGTCATTGCCCTGGCGGTGTTCTCGTCGGTGGTGTT
CGTGGTGGATCAGCGGCAGT

Product: HflK protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 476

Protein sequence:

>477_residues
MARYFFAVRQSGQARPLMPEISTQSSSMASPRPARGLWHRLRVLLSLNDPRWGRGDDNNNAEREGNKDEPKRQSKPPQDG
PPDLDELWRDFNRRLNNLFGRKDSGNGSDGPTPLRPGNGRGGSGLGIGVLLAVLVGLWLASGFFIVQEGQTGVILQFGRF
KYLATPGINWRLPYPVESHEIVNLSGVRTLEIGRTTQIKDTNLKDSSMLTQDENIVDVRFSVQYNIANPVDYLFYNRTDR
GGDEELVTQAAETSVREIVGRNKMDAVLYEGRDAVGRNLAESIQRILSAYKTGIRILSVNVQSVQPPEQVQAAFDDVTKA
GQDRERAISEGQAYANDVVPRAKGTAARLGEEAQGYKARVTARAEGDAARFASVQREYAKAPQVTRDRIYLETMQDIYAN
STKVLVDQSNGSLLYLPLDKLIAQTQGDTSRPAPAPGASAQDSGSAQGVPTPSNPSPANDADSRSREALRNRDRDSR

Sequences:

>Translated_477_residues
MARYFFAVRQSGQARPLMPEISTQSSSMASPRPARGLWHRLRVLLSLNDPRWGRGDDNNNAEREGNKDEPKRQSKPPQDG
PPDLDELWRDFNRRLNNLFGRKDSGNGSDGPTPLRPGNGRGGSGLGIGVLLAVLVGLWLASGFFIVQEGQTGVILQFGRF
KYLATPGINWRLPYPVESHEIVNLSGVRTLEIGRTTQIKDTNLKDSSMLTQDENIVDVRFSVQYNIANPVDYLFYNRTDR
GGDEELVTQAAETSVREIVGRNKMDAVLYEGRDAVGRNLAESIQRILSAYKTGIRILSVNVQSVQPPEQVQAAFDDVTKA
GQDRERAISEGQAYANDVVPRAKGTAARLGEEAQGYKARVTARAEGDAARFASVQREYAKAPQVTRDRIYLETMQDIYAN
STKVLVDQSNGSLLYLPLDKLIAQTQGDTSRPAPAPGASAQDSGSAQGVPTPSNPSPANDADSRSREALRNRDRDSR
>Mature_476_residues
ARYFFAVRQSGQARPLMPEISTQSSSMASPRPARGLWHRLRVLLSLNDPRWGRGDDNNNAEREGNKDEPKRQSKPPQDGP
PDLDELWRDFNRRLNNLFGRKDSGNGSDGPTPLRPGNGRGGSGLGIGVLLAVLVGLWLASGFFIVQEGQTGVILQFGRFK
YLATPGINWRLPYPVESHEIVNLSGVRTLEIGRTTQIKDTNLKDSSMLTQDENIVDVRFSVQYNIANPVDYLFYNRTDRG
GDEELVTQAAETSVREIVGRNKMDAVLYEGRDAVGRNLAESIQRILSAYKTGIRILSVNVQSVQPPEQVQAAFDDVTKAG
QDRERAISEGQAYANDVVPRAKGTAARLGEEAQGYKARVTARAEGDAARFASVQREYAKAPQVTRDRIYLETMQDIYANS
TKVLVDQSNGSLLYLPLDKLIAQTQGDTSRPAPAPGASAQDSGSAQGVPTPSNPSPANDADSRSREALRNRDRDSR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=282, Percent_Identity=38.2978723404255, Blast_Score=220, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 52455; Mature: 52324

Theoretical pI: Translated: 9.25; Mature: 9.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARYFFAVRQSGQARPLMPEISTQSSSMASPRPARGLWHRLRVLLSLNDPRWGRGDDNNN
CCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
AEREGNKDEPKRQSKPPQDGPPDLDELWRDFNRRLNNLFGRKDSGNGSDGPTPLRPGNGR
CCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GGSGLGIGVLLAVLVGLWLASGFFIVQEGQTGVILQFGRFKYLATPGINWRLPYPVESHE
CCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCEEEEECCCCCCEECCCCCCCC
IVNLSGVRTLEIGRTTQIKDTNLKDSSMLTQDENIVDVRFSVQYNIANPVDYLFYNRTDR
EEEECCEEEEECCCCCEECCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHEEEECCCCC
GGDEELVTQAAETSVREIVGRNKMDAVLYEGRDAVGRNLAESIQRILSAYKTGIRILSVN
CCCHHHHHHHHHHHHHHHHCCCCHHHHEECCCHHHHHHHHHHHHHHHHHHHCCEEEEEEE
VQSVQPPEQVQAAFDDVTKAGQDRERAISEGQAYANDVVPRAKGTAARLGEEAQGYKARV
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHCCCCCCCHHHHCCCHHCCCEEEE
TARAEGDAARFASVQREYAKAPQVTRDRIYLETMQDIYANSTKVLVDQSNGSLLYLPLDK
EEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHH
LIAQTQGDTSRPAPAPGASAQDSGSAQGVPTPSNPSPANDADSRSREALRNRDRDSR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ARYFFAVRQSGQARPLMPEISTQSSSMASPRPARGLWHRLRVLLSLNDPRWGRGDDNNN
CCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
AEREGNKDEPKRQSKPPQDGPPDLDELWRDFNRRLNNLFGRKDSGNGSDGPTPLRPGNGR
CCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
GGSGLGIGVLLAVLVGLWLASGFFIVQEGQTGVILQFGRFKYLATPGINWRLPYPVESHE
CCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEEECCEEEEECCCCCCEECCCCCCCC
IVNLSGVRTLEIGRTTQIKDTNLKDSSMLTQDENIVDVRFSVQYNIANPVDYLFYNRTDR
EEEECCEEEEECCCCCEECCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHEEEECCCCC
GGDEELVTQAAETSVREIVGRNKMDAVLYEGRDAVGRNLAESIQRILSAYKTGIRILSVN
CCCHHHHHHHHHHHHHHHHCCCCHHHHEECCCHHHHHHHHHHHHHHHHHHHCCEEEEEEE
VQSVQPPEQVQAAFDDVTKAGQDRERAISEGQAYANDVVPRAKGTAARLGEEAQGYKARV
CCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCHHHHHHCCCCCCCHHHHCCCHHCCCEEEE
TARAEGDAARFASVQREYAKAPQVTRDRIYLETMQDIYANSTKVLVDQSNGSLLYLPLDK
EEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEHHH
LIAQTQGDTSRPAPAPGASAQDSGSAQGVPTPSNPSPANDADSRSREALRNRDRDSR
HHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]