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The map label for this gene is hflX [H]

Identifier: 187928158

GI number: 187928158

Start: 1131829

End: 1133082

Strand: Direct

Name: hflX [H]

Synonym: Rpic_1065

Alternate gene names: 187928158

Gene position: 1131829-1133082 (Clockwise)

Preceding gene: 187928157

Following gene: 187928159

Centisome position: 28.71

GC content: 63.96

Gene sequence:

>1254_bases
TTGGCATCCCATCCCACCTCCAGCTCGGAGCCGACACGCGCTATTTTGGTCGCAGTCGATTTCGGCAAACATGATTTCCA
GGAAAGTCTGAGTGAACTGGCGCTACTGGCCTCGACCGCCGGCTCTGAACCGCTGCGCGCGGTTACCGGTAAGCGCACCA
GGCCCGATGCGGCGCTGTTCATCGGTGCTGGCAAGGCGGAAGAAGTGAAGATCGCCGCAGACGAGGAGGATGCGGAGATC
GTCATCTTCAACCACGCGCTGAGTCCCGCTCAGCAGCGTAACCTCGAGCGCTTTTTCGGGCGCCACGTAGTCGACCGGAC
TGGCCTCATCCTTGACATCTTCAGCCAGCGCGCGCAGAGCCACGTGGGCAAGGTGCAGGTAGAACTTGCTCGCGTGCGGT
ACCAGGCGGCCCGTCTGGTCCGGGCGTGGAGCCACTTGGAACGCCAGAAGGGCGGCGTCGGCCTGCGCGGCGGCCCGGGC
GAGCGTCAGCTCGAACTGGACCGCCGGATGCTGGACGAACGCGCCAAGCGTCTGTCGTCCGAGTTGGACAAACTCCAGCG
TCAGCACGACACCCAGCGCCGTTCACGCAGCCGCAACGACGCGTTTTCCGTCTCCCTGGTCGGCTATACCAACGCCGGCA
AATCGACGCTGTTCAATGCGCTGACCAAGGCACGCGCGTACGCTGCCAACCAGTTGTTCGCCACGCTGGATACGACCTCT
CGCCGTTTGTACCTGGAAGGGCTGGGCAATGTGGTGCTGTCGGACACGGTCGGTTTCATCCGCGATTTGCCGACGCAACT
GGTGGCCGCATTCCGTGCCACGCTGGAAGAAACCGTGCACGCCGACGTGCTGCTGCATGTGGTGGACGCCGCCAGCACAG
TCAAGCACGAGCAGATGGAGCAGGTCGATCGCGTGCTGGACGAAATCAATGCCAGCGGCATCCCCCAAATTCTGGTGATG
AACAAGATCGACGCGGCTGAGGAGCTGCGCGCGGCTGGCCCGCGCATCGAGCGAGACGAAACCGGCGCTGTGCGGCGCGT
GTTCGTTTCCGCCATAGAAGGGACCGGGCTCGATCTGTTGCGCGAAGCGCTGGTCGAGACTGCGATCCGCCTGCGTGAGC
ACCCCGCGTCGCATGGCGGCGATTTCGATCCGCGCTTCGACACCCGACGTGATTCGCCGCCGGCCCACCGTGACGAACTG
TCGCAAAGCTTGCCGAGCAGCGGTTCTTCCGCCAAAGGTGACGAAGAGGGCTGA

Upstream 100 bases:

>100_bases
CCGTGTGGACGAAGCGCCTGACGCCTGATTCTGCCTCGCTCCCGCCGCCGTCCGCGCGGCGGGACGCACCCACCCCGTTT
CTCCCTTCTCCATTCCCCGT

Downstream 100 bases:

>100_bases
TAGAATGGCCCGCTACTTCTTCGCAGTCAGACAATCAGGACAAGCCCGACCGCTCATGCCCGAGATTTCGACCCAGTCTT
CTTCCATGGCCTCGCCGCGT

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MASHPTSSSEPTRAILVAVDFGKHDFQESLSELALLASTAGSEPLRAVTGKRTRPDAALFIGAGKAEEVKIAADEEDAEI
VIFNHALSPAQQRNLERFFGRHVVDRTGLILDIFSQRAQSHVGKVQVELARVRYQAARLVRAWSHLERQKGGVGLRGGPG
ERQLELDRRMLDERAKRLSSELDKLQRQHDTQRRSRSRNDAFSVSLVGYTNAGKSTLFNALTKARAYAANQLFATLDTTS
RRLYLEGLGNVVLSDTVGFIRDLPTQLVAAFRATLEETVHADVLLHVVDAASTVKHEQMEQVDRVLDEINASGIPQILVM
NKIDAAEELRAAGPRIERDETGAVRRVFVSAIEGTGLDLLREALVETAIRLREHPASHGGDFDPRFDTRRDSPPAHRDEL
SQSLPSSGSSAKGDEEG

Sequences:

>Translated_417_residues
MASHPTSSSEPTRAILVAVDFGKHDFQESLSELALLASTAGSEPLRAVTGKRTRPDAALFIGAGKAEEVKIAADEEDAEI
VIFNHALSPAQQRNLERFFGRHVVDRTGLILDIFSQRAQSHVGKVQVELARVRYQAARLVRAWSHLERQKGGVGLRGGPG
ERQLELDRRMLDERAKRLSSELDKLQRQHDTQRRSRSRNDAFSVSLVGYTNAGKSTLFNALTKARAYAANQLFATLDTTS
RRLYLEGLGNVVLSDTVGFIRDLPTQLVAAFRATLEETVHADVLLHVVDAASTVKHEQMEQVDRVLDEINASGIPQILVM
NKIDAAEELRAAGPRIERDETGAVRRVFVSAIEGTGLDLLREALVETAIRLREHPASHGGDFDPRFDTRRDSPPAHRDEL
SQSLPSSGSSAKGDEEG
>Mature_416_residues
ASHPTSSSEPTRAILVAVDFGKHDFQESLSELALLASTAGSEPLRAVTGKRTRPDAALFIGAGKAEEVKIAADEEDAEIV
IFNHALSPAQQRNLERFFGRHVVDRTGLILDIFSQRAQSHVGKVQVELARVRYQAARLVRAWSHLERQKGGVGLRGGPGE
RQLELDRRMLDERAKRLSSELDKLQRQHDTQRRSRSRNDAFSVSLVGYTNAGKSTLFNALTKARAYAANQLFATLDTTSR
RLYLEGLGNVVLSDTVGFIRDLPTQLVAAFRATLEETVHADVLLHVVDAASTVKHEQMEQVDRVLDEINASGIPQILVMN
KIDAAEELRAAGPRIERDETGAVRRVFVSAIEGTGLDLLREALVETAIRLREHPASHGGDFDPRFDTRRDSPPAHRDELS
QSLPSSGSSAKGDEEG

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=240, Percent_Identity=35.8333333333333, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI310133116, Length=236, Percent_Identity=36.4406779661017, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI310124269, Length=215, Percent_Identity=36.2790697674419, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI310124267, Length=215, Percent_Identity=36.2790697674419, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI310124171, Length=215, Percent_Identity=36.2790697674419, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI310124169, Length=215, Percent_Identity=36.2790697674419, Blast_Score=112, Evalue=9e-25,
Organism=Escherichia coli, GI1790615, Length=373, Percent_Identity=53.3512064343164, Blast_Score=366, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17561038, Length=245, Percent_Identity=34.2857142857143, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24650079, Length=307, Percent_Identity=33.8762214983713, Blast_Score=115, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 45871; Mature: 45740

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASHPTSSSEPTRAILVAVDFGKHDFQESLSELALLASTAGSEPLRAVTGKRTRPDAALF
CCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEE
IGAGKAEEVKIAADEEDAEIVIFNHALSPAQQRNLERFFGRHVVDRTGLILDIFSQRAQS
EECCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HVGKVQVELARVRYQAARLVRAWSHLERQKGGVGLRGGPGERQLELDRRMLDERAKRLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELDKLQRQHDTQRRSRSRNDAFSVSLVGYTNAGKSTLFNALTKARAYAANQLFATLDTTS
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCC
RRLYLEGLGNVVLSDTVGFIRDLPTQLVAAFRATLEETVHADVLLHVVDAASTVKHEQME
CEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVDRVLDEINASGIPQILVMNKIDAAEELRAAGPRIERDETGAVRRVFVSAIEGTGLDLL
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
REALVETAIRLREHPASHGGDFDPRFDTRRDSPPAHRDELSQSLPSSGSSAKGDEEG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
ASHPTSSSEPTRAILVAVDFGKHDFQESLSELALLASTAGSEPLRAVTGKRTRPDAALF
CCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCEEE
IGAGKAEEVKIAADEEDAEIVIFNHALSPAQQRNLERFFGRHVVDRTGLILDIFSQRAQS
EECCCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HVGKVQVELARVRYQAARLVRAWSHLERQKGGVGLRGGPGERQLELDRRMLDERAKRLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELDKLQRQHDTQRRSRSRNDAFSVSLVGYTNAGKSTLFNALTKARAYAANQLFATLDTTS
HHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHEECCCC
RRLYLEGLGNVVLSDTVGFIRDLPTQLVAAFRATLEETVHADVLLHVVDAASTVKHEQME
CEEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVDRVLDEINASGIPQILVMNKIDAAEELRAAGPRIERDETGAVRRVFVSAIEGTGLDLL
HHHHHHHHHCCCCCCEEEEECCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHH
REALVETAIRLREHPASHGGDFDPRFDTRRDSPPAHRDELSQSLPSSGSSAKGDEEG
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]