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The map label for this gene is yfjP [H]

Identifier: 187928102

GI number: 187928102

Start: 1066072

End: 1066944

Strand: Direct

Name: yfjP [H]

Synonym: Rpic_1009

Alternate gene names: 187928102

Gene position: 1066072-1066944 (Clockwise)

Preceding gene: 187928101

Following gene: 187928103

Centisome position: 27.04

GC content: 63.46

Gene sequence:

>873_bases
ATGAGCGCGGTGGCCAAGAAAGCCAACGTAGGACGCAGCACCGCTGCCAAGAAAGCGCCGGCGGTGACGGTGTCGGCTGC
CAAGAAAGCAGTCGCCAGAAAAGTCGACGGCGTGGCGAGCAAGACGGTCGTCGCCAAGAGCGCACCGATCAAGGCCGCCA
AGGCCCCGGCCAAACGCGTGCCTGCGAGCAAGGTGCCACTGCCCGAAGCACTTGCCGCCAGCGAGACGCTGCCTGTGCCC
GCCGAAGTGGTGCTCTCGGGGCCGCCCGAGTACTGGCAAGAAGCTTGCGCAGACCTGATGAAGCGCGACCGTATCCTGCG
CAAGATCATTCCGACGTGTGGCCCGGCGCACTTGGCTTCGCGCGGCGATCCGTTCGTCACGCTGGCGCGCTCGATTGTCG
GGCAACAGATTTCCGTGAAGGCTGCGCAGTCGGTGTGGGAACGCGTCGTGGGTGTGTGCCCCAAGCTCGTGCCCGCCCAG
TTCCTGCGTGCGGGCCAGGAAAAGCTGGCGGGTTGCGGCCTGTCCAAACGCAAGGCCGAGTACATCCTTGATCTGGCCGA
TCACTTTCGCAACGGCACCGTGCACGTCGCCAAGTGGGCCGAGATGGAAGACGAAGACGTGATCGCCGAGTTGACGCAAA
TCCGCGGCATCGGCAGATGGACAGCAGAGATGTTCCTGATGTTCAATCTGATGCGCCCGAACGTGCTGCCGCTGGACGAT
ATCGGCCTCATCAACGCGATTTCCCAGAATTATTTCAGTGGCGAACCCGTCACTCGCAGCGAGGCGCGGGAAGTGGCCGC
CAACTGGGAGCCATGGCGCACCGTGGCCACTTGGTATATGTGGCGCAGCCTAGACACGGCGACCACCTATTGA

Upstream 100 bases:

>100_bases
CCCGCGATTTTGCCCGCGCTGATGCCATCCGTGCCGATCTGCTGGCCGCCGGCATTGTCCTCGAAGACAAACCGGGTGGC
CTGACCGAGTGGAGACGCGC

Downstream 100 bases:

>100_bases
TCTGTTCATTTCGATGAAACGGAGCGCGTCGCCGGGCGGTCAAAATCCGGTAGAATGCGCGCCTTCAAGAGCCTTTCAGA
AGATCCATGAAAACAACCTT

Product: HhH-GPD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSAVAKKANVGRSTAAKKAPAVTVSAAKKAVARKVDGVASKTVVAKSAPIKAAKAPAKRVPASKVPLPEALAASETLPVP
AEVVLSGPPEYWQEACADLMKRDRILRKIIPTCGPAHLASRGDPFVTLARSIVGQQISVKAAQSVWERVVGVCPKLVPAQ
FLRAGQEKLAGCGLSKRKAEYILDLADHFRNGTVHVAKWAEMEDEDVIAELTQIRGIGRWTAEMFLMFNLMRPNVLPLDD
IGLINAISQNYFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDTATTY

Sequences:

>Translated_290_residues
MSAVAKKANVGRSTAAKKAPAVTVSAAKKAVARKVDGVASKTVVAKSAPIKAAKAPAKRVPASKVPLPEALAASETLPVP
AEVVLSGPPEYWQEACADLMKRDRILRKIIPTCGPAHLASRGDPFVTLARSIVGQQISVKAAQSVWERVVGVCPKLVPAQ
FLRAGQEKLAGCGLSKRKAEYILDLADHFRNGTVHVAKWAEMEDEDVIAELTQIRGIGRWTAEMFLMFNLMRPNVLPLDD
IGLINAISQNYFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDTATTY
>Mature_289_residues
SAVAKKANVGRSTAAKKAPAVTVSAAKKAVARKVDGVASKTVVAKSAPIKAAKAPAKRVPASKVPLPEALAASETLPVPA
EVVLSGPPEYWQEACADLMKRDRILRKIIPTCGPAHLASRGDPFVTLARSIVGQQISVKAAQSVWERVVGVCPKLVPAQF
LRAGQEKLAGCGLSKRKAEYILDLADHFRNGTVHVAKWAEMEDEDVIAELTQIRGIGRWTAEMFLMFNLMRPNVLPLDDI
GLINAISQNYFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDTATTY

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=264, Percent_Identity=30.6818181818182, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 31512; Mature: 31381

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVAKKANVGRSTAAKKAPAVTVSAAKKAVARKVDGVASKTVVAKSAPIKAAKAPAKRV
CCCHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHC
PASKVPLPEALAASETLPVPAEVVLSGPPEYWQEACADLMKRDRILRKIIPTCGPAHLAS
CCCCCCCCHHHHCCCCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHC
RGDPFVTLARSIVGQQISVKAAQSVWERVVGVCPKLVPAQFLRAGQEKLAGCGLSKRKAE
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHH
YILDLADHFRNGTVHVAKWAEMEDEDVIAELTQIRGIGRWTAEMFLMFNLMRPNVLPLDD
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCH
IGLINAISQNYFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDTATTY
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAVAKKANVGRSTAAKKAPAVTVSAAKKAVARKVDGVASKTVVAKSAPIKAAKAPAKRV
CCHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHC
PASKVPLPEALAASETLPVPAEVVLSGPPEYWQEACADLMKRDRILRKIIPTCGPAHLAS
CCCCCCCCHHHHCCCCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHC
RGDPFVTLARSIVGQQISVKAAQSVWERVVGVCPKLVPAQFLRAGQEKLAGCGLSKRKAE
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHH
YILDLADHFRNGTVHVAKWAEMEDEDVIAELTQIRGIGRWTAEMFLMFNLMRPNVLPLDD
HHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCH
IGLINAISQNYFSGEPVTRSEAREVAANWEPWRTVATWYMWRSLDTATTY
HHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]