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The map label for this gene is cysS [H]

Identifier: 187928101

GI number: 187928101

Start: 1064684

End: 1066075

Strand: Direct

Name: cysS [H]

Synonym: Rpic_1008

Alternate gene names: 187928101

Gene position: 1064684-1066075 (Clockwise)

Preceding gene: 187928096

Following gene: 187928102

Centisome position: 27.0

GC content: 63.43

Gene sequence:

>1392_bases
ATGGAATCACTCAAGATCTACAACACGCTCGCGCGTGAGAAACAGACGTTCGTCCCCATCGAGCCCGGCCGCGTGCGCAT
GTACGTGTGTGGCATGACGGTGTACGACTACTGTCACGTCGGGCATGCGCGGGTCATGGTGGTGTTCGACATGGTGCAGC
GTTGGCTGCGCGCGGCCGGTTACGACGTCACCTACGTGCGCAACATCACCGACATCGACGACAAGATCATCAAGCGTGCG
GTCGAGAACGGCGAGACGATGAGTGCGCTGACGGGCCGCTTCATCGCTGCCATGCACGAAGACGCCGATGCGCTTGGCGT
GCAGCGCCCGGACCACGAACCCCGCGCCACCGAATACGTGCCGCAGATGCTGAGCATGATCGGCAGGCTGCAGACGAACG
GCCTCGCCTATCAGGCGACCGACGGCGATGTGAACTACGCGGTGCGCAAATTCCCCGGTTACGGCAAGCTGTCCGGCAAG
TCGCTCGAAGACCTGCGCGCCGGCGAGCGCGTGGCGGCCAATGATGCCAAGCAGGACCCGCTCGACTTCGTGCTGTGGAA
ATCCGCCAAGGCCGACGAACCGGCTGAATCGCGCTGGGCGTCGCCGTGGGGCGAGGGCCGTCCGGGCTGGCATATCGAAT
GCTCGGCGATGAGCTGCGAGCTGCTGGGCGAGCATTTCGATCTGCACGGTGGCGGCGCCGATCTGCAGTTCCCGCATCAC
GAGAATGAAATTGCGCAGTCCGAAGGGGCGACCGGCAAGACGTTCGTCAACATGTGGATGCACAACGGCTTCGTCCGTGT
GAATGACGAGAAGATGTCGAAATCGCTCGGCAACTTCTTCACCATCCGTGACGTGCTGAAAGTGTACGACGCGGAAGTCG
TGCGTTTCTTCATCCTGCGCTCGCACTATCGCAGTGACCTGAATTACAGCGACGCCCACCTCGACGACGCGCGCCATGCG
CTCACGCGCCTGTACACCGCGCTCAAGGATGTGCCGGCGGCGGTGGGTGCAAAACCCGACTGGAGCGAGTCGCATGGCAA
GCGCTTCCTCGAAGCGATGAACGACGACTTCAATACGCCGGTCGCCGTGTCGGTGTTGTTTGAACTCGCGAGCGAAGTGA
ACAAAACGCGCTCGCCCGAACTGGCCAGCCAACTGGCTGCGCTGGCCGGCGTGATCGGCCTGCTCGGCCGCGATCCGCAT
GTGTTCCTGCAGGGCGGTGTGTCGGCCGATGGTGTGGACGCGGCAGAAGTGGAAGCGCGTATCGAAGAGCGCCGCGCCGC
CAAGGCTGCCCGCGATTTTGCCCGCGCTGATGCCATCCGTGCCGATCTGCTGGCCGCCGGCATTGTCCTCGAAGACAAAC
CGGGTGGCCTGACCGAGTGGAGACGCGCATGA

Upstream 100 bases:

>100_bases
GTTTTGCAGGCGCCGTGCCGGCGCCGATTGCCTCCAATTTAGTCCGCCCGCAACGTTGTACCTCGCATGCGCGGCGCGCT
GAGTCTCCCGACACCGCTTC

Downstream 100 bases:

>100_bases
GCGCGGTGGCCAAGAAAGCCAACGTAGGACGCAGCACCGCTGCCAAGAAAGCGCCGGCGGTGACGGTGTCGGCTGCCAAG
AAAGCAGTCGCCAGAAAAGT

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MESLKIYNTLAREKQTFVPIEPGRVRMYVCGMTVYDYCHVGHARVMVVFDMVQRWLRAAGYDVTYVRNITDIDDKIIKRA
VENGETMSALTGRFIAAMHEDADALGVQRPDHEPRATEYVPQMLSMIGRLQTNGLAYQATDGDVNYAVRKFPGYGKLSGK
SLEDLRAGERVAANDAKQDPLDFVLWKSAKADEPAESRWASPWGEGRPGWHIECSAMSCELLGEHFDLHGGGADLQFPHH
ENEIAQSEGATGKTFVNMWMHNGFVRVNDEKMSKSLGNFFTIRDVLKVYDAEVVRFFILRSHYRSDLNYSDAHLDDARHA
LTRLYTALKDVPAAVGAKPDWSESHGKRFLEAMNDDFNTPVAVSVLFELASEVNKTRSPELASQLAALAGVIGLLGRDPH
VFLQGGVSADGVDAAEVEARIEERRAAKAARDFARADAIRADLLAAGIVLEDKPGGLTEWRRA

Sequences:

>Translated_463_residues
MESLKIYNTLAREKQTFVPIEPGRVRMYVCGMTVYDYCHVGHARVMVVFDMVQRWLRAAGYDVTYVRNITDIDDKIIKRA
VENGETMSALTGRFIAAMHEDADALGVQRPDHEPRATEYVPQMLSMIGRLQTNGLAYQATDGDVNYAVRKFPGYGKLSGK
SLEDLRAGERVAANDAKQDPLDFVLWKSAKADEPAESRWASPWGEGRPGWHIECSAMSCELLGEHFDLHGGGADLQFPHH
ENEIAQSEGATGKTFVNMWMHNGFVRVNDEKMSKSLGNFFTIRDVLKVYDAEVVRFFILRSHYRSDLNYSDAHLDDARHA
LTRLYTALKDVPAAVGAKPDWSESHGKRFLEAMNDDFNTPVAVSVLFELASEVNKTRSPELASQLAALAGVIGLLGRDPH
VFLQGGVSADGVDAAEVEARIEERRAAKAARDFARADAIRADLLAAGIVLEDKPGGLTEWRRA
>Mature_463_residues
MESLKIYNTLAREKQTFVPIEPGRVRMYVCGMTVYDYCHVGHARVMVVFDMVQRWLRAAGYDVTYVRNITDIDDKIIKRA
VENGETMSALTGRFIAAMHEDADALGVQRPDHEPRATEYVPQMLSMIGRLQTNGLAYQATDGDVNYAVRKFPGYGKLSGK
SLEDLRAGERVAANDAKQDPLDFVLWKSAKADEPAESRWASPWGEGRPGWHIECSAMSCELLGEHFDLHGGGADLQFPHH
ENEIAQSEGATGKTFVNMWMHNGFVRVNDEKMSKSLGNFFTIRDVLKVYDAEVVRFFILRSHYRSDLNYSDAHLDDARHA
LTRLYTALKDVPAAVGAKPDWSESHGKRFLEAMNDDFNTPVAVSVLFELASEVNKTRSPELASQLAALAGVIGLLGRDPH
VFLQGGVSADGVDAAEVEARIEERRAAKAARDFARADAIRADLLAAGIVLEDKPGGLTEWRRA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=506, Percent_Identity=35.5731225296443, Blast_Score=248, Evalue=6e-66,
Organism=Homo sapiens, GI303304987, Length=337, Percent_Identity=34.7181008902077, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI21269877, Length=337, Percent_Identity=34.7181008902077, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI62240992, Length=337, Percent_Identity=34.7181008902077, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI10835051, Length=337, Percent_Identity=34.7181008902077, Blast_Score=182, Evalue=6e-46,
Organism=Escherichia coli, GI1786737, Length=465, Percent_Identity=56.5591397849462, Blast_Score=512, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17509797, Length=269, Percent_Identity=37.546468401487, Blast_Score=168, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17509795, Length=269, Percent_Identity=37.546468401487, Blast_Score=168, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6324082, Length=331, Percent_Identity=33.2326283987915, Blast_Score=183, Evalue=4e-47,
Organism=Drosophila melanogaster, GI19922218, Length=409, Percent_Identity=36.919315403423, Blast_Score=231, Evalue=9e-61,
Organism=Drosophila melanogaster, GI19922364, Length=338, Percent_Identity=34.9112426035503, Blast_Score=180, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51461; Mature: 51461

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLKIYNTLAREKQTFVPIEPGRVRMYVCGMTVYDYCHVGHARVMVVFDMVQRWLRAAG
CCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHCC
YDVTYVRNITDIDDKIIKRAVENGETMSALTGRFIAAMHEDADALGVQRPDHEPRATEYV
CCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHH
PQMLSMIGRLQTNGLAYQATDGDVNYAVRKFPGYGKLSGKSLEDLRAGERVAANDAKQDP
HHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKSAKADEPAESRWASPWGEGRPGWHIECSAMSCELLGEHFDLHGGGADLQFPHH
CCEEEECCCCCCCCHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCC
ENEIAQSEGATGKTFVNMWMHNGFVRVNDEKMSKSLGNFFTIRDVLKVYDAEVVRFFILR
CHHHHHCCCCCCHHHHHHHHHCCEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SHYRSDLNYSDAHLDDARHALTRLYTALKDVPAAVGAKPDWSESHGKRFLEAMNDDFNTP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCH
VAVSVLFELASEVNKTRSPELASQLAALAGVIGLLGRDPHVFLQGGVSADGVDAAEVEAR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHH
IEERRAAKAARDFARADAIRADLLAAGIVLEDKPGGLTEWRRA
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHCCC
>Mature Secondary Structure
MESLKIYNTLAREKQTFVPIEPGRVRMYVCGMTVYDYCHVGHARVMVVFDMVQRWLRAAG
CCCHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHCC
YDVTYVRNITDIDDKIIKRAVENGETMSALTGRFIAAMHEDADALGVQRPDHEPRATEYV
CCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHCCCCCCCCCHHHHHH
PQMLSMIGRLQTNGLAYQATDGDVNYAVRKFPGYGKLSGKSLEDLRAGERVAANDAKQDP
HHHHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCCCCCCHHHHHCCCCHHCCCCCCCC
LDFVLWKSAKADEPAESRWASPWGEGRPGWHIECSAMSCELLGEHFDLHGGGADLQFPHH
CCEEEECCCCCCCCHHHHCCCCCCCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCCCCCC
ENEIAQSEGATGKTFVNMWMHNGFVRVNDEKMSKSLGNFFTIRDVLKVYDAEVVRFFILR
CHHHHHCCCCCCHHHHHHHHHCCEEEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
SHYRSDLNYSDAHLDDARHALTRLYTALKDVPAAVGAKPDWSESHGKRFLEAMNDDFNTP
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCH
VAVSVLFELASEVNKTRSPELASQLAALAGVIGLLGRDPHVFLQGGVSADGVDAAEVEAR
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHH
IEERRAAKAARDFARADAIRADLLAAGIVLEDKPGGLTEWRRA
HHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]