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The map label for this gene is lpxH [H]

Identifier: 187928097

GI number: 187928097

Start: 1061794

End: 1062612

Strand: Reverse

Name: lpxH [H]

Synonym: Rpic_1004

Alternate gene names: 187928097

Gene position: 1062612-1061794 (Counterclockwise)

Preceding gene: 187928098

Following gene: 187928094

Centisome position: 26.95

GC content: 64.47

Gene sequence:

>819_bases
ATGATCGACGCAGCGCACGCCGCACAGGCCTCCGCGCTGAAGACACCGGTCCGGGTTTCCGGGCCGGTGTTTTTTATTTC
GGATCTGCACCTCACGGCCAGCATGCCGGCCACCGCCGCTGCGTTCGAGCGCTTCCTGCGCACGCGCGCCCGCGAGGCAC
GCACGCTCGTCATCCTGGGTGACTTCTTTGAATACTGGGTCGGCGATGAAGAGTTGGCTGATCCGTTCCACCAGCACATC
GCCAGCCTGCTCGCAGAGCTTTCAGTGGCCGGCACGCGCGTGCTGTTCATGCACGGCAATCGCGACTTCCTGCTCGGCAA
GCGTTTCTTGAATGCCGCGCACGCTACGCTGCTACCTGATCCCACCGTGCTGGAAGCGGATGATGGCCAGCGCATCGTGC
TTGCCCACGGCGACGCCCTCTGCACGCGCGACGCGGCCTACATGCGCTTTCGCCACTGGACGCGCAAGCGCTGGGTGCAG
CGGATATTCCTGACGATGCCGCTGCGCTGGCGGCTGAAGATCGCGCAGAAGATGCGCGCAGAAAGCGAAGCTGGCCGCGC
CATGTCCGCCAATGTTGCCGGCGAACCCCGCGCCGCTGCGATGATGGGCGACGTCGCACCTGATGCGGTGGACGCGCTGC
TCAAGGCATCCAATACGTCCACGCTCATCCACGGCCACACGCACCGCCCGCAATTGCATCACGAGCCGAGCGGCAGCCGC
TGGGTACTTTCCGACTGGGATTTCGATCAAGCACACCCGCGCGGCAGTTTCCTCAAACTGCAAGACGGCACGCTGACGGT
CGAGCAAGTGACGACATAA

Upstream 100 bases:

>100_bases
ATGTGGTCGACAAAATCCGCTCGGTGCGCACGGGCAACCGCGGCTTCCACCAGGACGTGCCGATGGAAGACGTGATCATC
GAAAGCGCCGAAGTGATCGA

Downstream 100 bases:

>100_bases
GCCGTCGCCACCGGCCCTTTGCTTACTTGAGCATCCGCTTCAGCTCGCTCGCATCGAACGGATCGTTCGGCGAGTTTTCC
AGGTGCGCGCCCAGGCGATC

Product: UDP-2,3-diacylglucosamine hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MIDAAHAAQASALKTPVRVSGPVFFISDLHLTASMPATAAAFERFLRTRAREARTLVILGDFFEYWVGDEELADPFHQHI
ASLLAELSVAGTRVLFMHGNRDFLLGKRFLNAAHATLLPDPTVLEADDGQRIVLAHGDALCTRDAAYMRFRHWTRKRWVQ
RIFLTMPLRWRLKIAQKMRAESEAGRAMSANVAGEPRAAAMMGDVAPDAVDALLKASNTSTLIHGHTHRPQLHHEPSGSR
WVLSDWDFDQAHPRGSFLKLQDGTLTVEQVTT

Sequences:

>Translated_272_residues
MIDAAHAAQASALKTPVRVSGPVFFISDLHLTASMPATAAAFERFLRTRAREARTLVILGDFFEYWVGDEELADPFHQHI
ASLLAELSVAGTRVLFMHGNRDFLLGKRFLNAAHATLLPDPTVLEADDGQRIVLAHGDALCTRDAAYMRFRHWTRKRWVQ
RIFLTMPLRWRLKIAQKMRAESEAGRAMSANVAGEPRAAAMMGDVAPDAVDALLKASNTSTLIHGHTHRPQLHHEPSGSR
WVLSDWDFDQAHPRGSFLKLQDGTLTVEQVTT
>Mature_272_residues
MIDAAHAAQASALKTPVRVSGPVFFISDLHLTASMPATAAAFERFLRTRAREARTLVILGDFFEYWVGDEELADPFHQHI
ASLLAELSVAGTRVLFMHGNRDFLLGKRFLNAAHATLLPDPTVLEADDGQRIVLAHGDALCTRDAAYMRFRHWTRKRWVQ
RIFLTMPLRWRLKIAQKMRAESEAGRAMSANVAGEPRAAAMMGDVAPDAVDALLKASNTSTLIHGHTHRPQLHHEPSGSR
WVLSDWDFDQAHPRGSFLKLQDGTLTVEQVTT

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=241, Percent_Identity=42.7385892116183, Blast_Score=179, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004843
- InterPro:   IPR010138 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: 3.6.1.-

Molecular weight: Translated: 30321; Mature: 30321

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDAAHAAQASALKTPVRVSGPVFFISDLHLTASMPATAAAFERFLRTRAREARTLVILG
CCCCHHHHHHHHHCCCEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCEEEEEEE
DFFEYWVGDEELADPFHQHIASLLAELSVAGTRVLFMHGNRDFLLGKRFLNAAHATLLPD
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCC
PTVLEADDGQRIVLAHGDALCTRDAAYMRFRHWTRKRWVQRIFLTMPLRWRLKIAQKMRA
CCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ESEAGRAMSANVAGEPRAAAMMGDVAPDAVDALLKASNTSTLIHGHTHRPQLHHEPSGSR
HHHCCCEEECCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCE
WVLSDWDFDQAHPRGSFLKLQDGTLTVEQVTT
EEEECCCCCCCCCCCCEEEEECCEEEEEEECC
>Mature Secondary Structure
MIDAAHAAQASALKTPVRVSGPVFFISDLHLTASMPATAAAFERFLRTRAREARTLVILG
CCCCHHHHHHHHHCCCEEECCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCEEEEEEE
DFFEYWVGDEELADPFHQHIASLLAELSVAGTRVLFMHGNRDFLLGKRFLNAAHATLLPD
HHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCC
PTVLEADDGQRIVLAHGDALCTRDAAYMRFRHWTRKRWVQRIFLTMPLRWRLKIAQKMRA
CCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ESEAGRAMSANVAGEPRAAAMMGDVAPDAVDALLKASNTSTLIHGHTHRPQLHHEPSGSR
HHHCCCEEECCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCE
WVLSDWDFDQAHPRGSFLKLQDGTLTVEQVTT
EEEECCCCCCCCCCCCEEEEECCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]