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The map label for this gene is rpoE [H]

Identifier: 187928015

GI number: 187928015

Start: 974351

End: 974950

Strand: Direct

Name: rpoE [H]

Synonym: Rpic_0920

Alternate gene names: 187928015

Gene position: 974351-974950 (Clockwise)

Preceding gene: 187928014

Following gene: 187928016

Centisome position: 24.71

GC content: 60.0

Gene sequence:

>600_bases
GTGAGCGAACGCGAAGCCGACCAGATCCTCGTCGAGCGCGTCCAGCAAGGCGACAAGCGAGCGTTTGAACTGCTGGTGGT
CAAGTACCACCGGAAGATCATTCGGCTCGTCTCGCGCCTGATCCGTGACCCGGCCGAAGTCGAGGATGTGGCACAGGATG
CCTTTATCAAGGCCTACCGTGCGTTGCCCCAGTTCCGGGGAGAATCCGCGTTCTATACGTGGCTGTATCGCATCGCCGTC
AACACGGCCAAGAATTACCTGGCGACTCAGGGCCGGCGCCCGGAATCGTCCAGCGACATCGATACCGAAGAGGCTGAAAC
TTTTGCCGACGGTGAGCTACTAAGGGATATCAATACGCCGGACTCCATGCTGCACACCAAGCAGGTGGCCGAAACGGTCA
ACCGCGCAATGGAAGCGCTGCCCGAAGAATTGCGTACCGCAATCACACTCCGGGAGATCGAGGGTCTGAGCTATGAGGAA
ATCGCCGAAGCGATGGAATGCCCGATCGGCACAGTCCGATCCCGCATTTTCCGGGCGCGCGAGGCGATTGCCGAGAAATT
GCGCCCCCTGCTGGGAACAGTGGAGGGCAAACGGTGGTAG

Upstream 100 bases:

>100_bases
CCGCCGCGGGTGGTTTCCCAGGCGTCCGGTGTGTCGTAGGTAAAATACAACGTTTCCAAGTCACAAAAATTCAAGGCGAT
ACACTGCAGGTGAAGAATCC

Downstream 100 bases:

>100_bases
CCAGCCGATATGACAAGCCGGCGGCCCATGCGGCTGCAAACGGTGAAACCTCGGGAAGTCTTCTCTCGGATCGTTGATTG
GACGTTGGAGTTTTTGGGGT

Product: RNA polymerase sigma factor RpoE

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MSEREADQILVERVQQGDKRAFELLVVKYHRKIIRLVSRLIRDPAEVEDVAQDAFIKAYRALPQFRGESAFYTWLYRIAV
NTAKNYLATQGRRPESSSDIDTEEAETFADGELLRDINTPDSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEE
IAEAMECPIGTVRSRIFRAREAIAEKLRPLLGTVEGKRW

Sequences:

>Translated_199_residues
MSEREADQILVERVQQGDKRAFELLVVKYHRKIIRLVSRLIRDPAEVEDVAQDAFIKAYRALPQFRGESAFYTWLYRIAV
NTAKNYLATQGRRPESSSDIDTEEAETFADGELLRDINTPDSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEE
IAEAMECPIGTVRSRIFRAREAIAEKLRPLLGTVEGKRW
>Mature_198_residues
SEREADQILVERVQQGDKRAFELLVVKYHRKIIRLVSRLIRDPAEVEDVAQDAFIKAYRALPQFRGESAFYTWLYRIAVN
TAKNYLATQGRRPESSSDIDTEEAETFADGELLRDINTPDSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEEI
AEAMECPIGTVRSRIFRAREAIAEKLRPLLGTVEGKRW

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=191, Percent_Identity=62.303664921466, Blast_Score=244, Evalue=2e-66,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 22856; Mature: 22725

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS01063 SIGMA70_ECF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEREADQILVERVQQGDKRAFELLVVKYHRKIIRLVSRLIRDPAEVEDVAQDAFIKAYR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ALPQFRGESAFYTWLYRIAVNTAKNYLATQGRRPESSSDIDTEEAETFADGELLRDINTP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEEIAEAMECPIGTVRSRIFRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHH
EAIAEKLRPLLGTVEGKRW
HHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SEREADQILVERVQQGDKRAFELLVVKYHRKIIRLVSRLIRDPAEVEDVAQDAFIKAYR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ALPQFRGESAFYTWLYRIAVNTAKNYLATQGRRPESSSDIDTEEAETFADGELLRDINTP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DSMLHTKQVAETVNRAMEALPEELRTAITLREIEGLSYEEIAEAMECPIGTVRSRIFRAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHH
EAIAEKLRPLLGTVEGKRW
HHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]