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The map label for this gene is fabD [H]

Identifier: 187928011

GI number: 187928011

Start: 970285

End: 971214

Strand: Direct

Name: fabD [H]

Synonym: Rpic_0916

Alternate gene names: 187928011

Gene position: 970285-971214 (Clockwise)

Preceding gene: 187928010

Following gene: 187928012

Centisome position: 24.61

GC content: 65.59

Gene sequence:

>930_bases
ATGACATTCGCTTTCGTCTTCCCCGGCCAGGGTTCGCAATCGGTCGGCATGCTCAATGCGTTTGCCGATCATCCGGCCGT
GGCCGCTACGCTGGTCGAGGCGTCCGACGCGCTGGGCCAGGACATCGGCAAGCTGATTGCCGAAGGCCCGGCTGAAGAGC
TGAACCTGACGACCAATACGCAACCCGTCATGCTGACGGCGGCAGTTGCCGTCTATCGTGCATGGCAAGCTGCCGGCGGC
CCGACGCCGACCGTCGTGGCTGGGCATAGCCTTGGCGAGTATTCGGCGCTTGTCGCCGCGGGCGCCATCGCGTTCCAAGA
CGCTGTACCGTTGGTGCGTTTCCGCGCCAAGGCGATGCAGGAAGCTGTGCCGGTGGGCGAGGGCGGTATGGCTGCGATCC
TCGGCCTGTCGGACGATGACGTGCGCGCCGCATGCGCGGAAGCTTCGGTCGCAGGCGTCGTCGAAGCCGTGAACTTCAAC
GCGCCGGCCCAGGTGGTGATCGCCGGTGCCAAGGCGGCCGTCGAGAAGGCTTGCGAAATCGCCAAGGCCAAGGGTGCCAA
GCGCGCGCTGCCGCTGCCGGTGTCGGCGCCGTTTCACTCGTCGCTGCTCAAGCCGGCGTCGGATCGTCTGCGGGAGTATC
TCGCCAACGTGGCCGTCACCACCCCGGTGATCCCCGTCATCAATAACGTGGACGTTGCTGTCGTGAGCGACCCGGCGGCC
ATCAAGGATGCGCTGGTGCGCCAGGCAGCATCGCCGGTGCGCTGGGTTGAGACCATCCAGAAGATGAAGGGTGACGGCAT
TACCCGCGTGGTCGAATGCGGCCCGGGCAAGGTGCTGGCCGGTCTGGTCAAGCGTATCGATGGGGAGATCGTCGGTGACG
CGATCTTCGATCCGGCGTCGCTGGAAGCCGTGCTGGGTCAACTCAAATAA

Upstream 100 bases:

>100_bases
GCCAGCATGTGATGCTCGAGGGCGTGGGCGGCGGCTTCACATGGGGCGCCGCGCTGCTGCGCTTCTGATTGACGAATTTC
CAGAACGAACAATACGAGCC

Downstream 100 bases:

>100_bases
TCAACGGGATTCGTATGACCCAAGCATTGAACAATCAGGTTGCGCTCGTTACCGGTGCCTCGCGCGGCATCGGCCGTGCC
ATCGCGCTGGAACTGGCACG

Product: cyclic nucleotide-binding protein

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTFAFVFPGQGSQSVGMLNAFADHPAVAATLVEASDALGQDIGKLIAEGPAEELNLTTNTQPVMLTAAVAVYRAWQAAGG
PTPTVVAGHSLGEYSALVAAGAIAFQDAVPLVRFRAKAMQEAVPVGEGGMAAILGLSDDDVRAACAEASVAGVVEAVNFN
APAQVVIAGAKAAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDRLREYLANVAVTTPVIPVINNVDVAVVSDPAA
IKDALVRQAASPVRWVETIQKMKGDGITRVVECGPGKVLAGLVKRIDGEIVGDAIFDPASLEAVLGQLK

Sequences:

>Translated_309_residues
MTFAFVFPGQGSQSVGMLNAFADHPAVAATLVEASDALGQDIGKLIAEGPAEELNLTTNTQPVMLTAAVAVYRAWQAAGG
PTPTVVAGHSLGEYSALVAAGAIAFQDAVPLVRFRAKAMQEAVPVGEGGMAAILGLSDDDVRAACAEASVAGVVEAVNFN
APAQVVIAGAKAAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDRLREYLANVAVTTPVIPVINNVDVAVVSDPAA
IKDALVRQAASPVRWVETIQKMKGDGITRVVECGPGKVLAGLVKRIDGEIVGDAIFDPASLEAVLGQLK
>Mature_308_residues
TFAFVFPGQGSQSVGMLNAFADHPAVAATLVEASDALGQDIGKLIAEGPAEELNLTTNTQPVMLTAAVAVYRAWQAAGGP
TPTVVAGHSLGEYSALVAAGAIAFQDAVPLVRFRAKAMQEAVPVGEGGMAAILGLSDDDVRAACAEASVAGVVEAVNFNA
PAQVVIAGAKAAVEKACEIAKAKGAKRALPLPVSAPFHSSLLKPASDRLREYLANVAVTTPVIPVINNVDVAVVSDPAAI
KDALVRQAASPVRWVETIQKMKGDGITRVVECGPGKVLAGLVKRIDGEIVGDAIFDPASLEAVLGQLK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=33.2225913621262, Blast_Score=154, Evalue=7e-38,
Organism=Escherichia coli, GI1787334, Length=304, Percent_Identity=55.921052631579, Blast_Score=313, Evalue=9e-87,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=32.3024054982818, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17550940, Length=234, Percent_Identity=29.9145299145299, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI212642053, Length=292, Percent_Identity=27.3972602739726, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665753, Length=303, Percent_Identity=33.993399339934, Blast_Score=140, Evalue=7e-34,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31560; Mature: 31428

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00889 CNMP_BINDING_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAFVFPGQGSQSVGMLNAFADHPAVAATLVEASDALGQDIGKLIAEGPAEELNLTTNT
CEEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCC
QPVMLTAAVAVYRAWQAAGGPTPTVVAGHSLGEYSALVAAGAIAFQDAVPLVRFRAKAMQ
CCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVPVGEGGMAAILGLSDDDVRAACAEASVAGVVEAVNFNAPAQVVIAGAKAAVEKACEI
HHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDRLREYLANVAVTTPVIPVINNVDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCHH
IKDALVRQAASPVRWVETIQKMKGDGITRVVECGPGKVLAGLVKRIDGEIVGDAIFDPAS
HHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEECHHHCCHHH
LEAVLGQLK
HHHHHHCCC
>Mature Secondary Structure 
TFAFVFPGQGSQSVGMLNAFADHPAVAATLVEASDALGQDIGKLIAEGPAEELNLTTNT
EEEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCC
QPVMLTAAVAVYRAWQAAGGPTPTVVAGHSLGEYSALVAAGAIAFQDAVPLVRFRAKAMQ
CCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVPVGEGGMAAILGLSDDDVRAACAEASVAGVVEAVNFNAPAQVVIAGAKAAVEKACEI
HHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDRLREYLANVAVTTPVIPVINNVDVAVVSDPAA
HHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCHH
IKDALVRQAASPVRWVETIQKMKGDGITRVVECGPGKVLAGLVKRIDGEIVGDAIFDPAS
HHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHCCCEECHHHCCHHH
LEAVLGQLK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]