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The map label for this gene is nudL [H]

Identifier: 187927903

GI number: 187927903

Start: 852803

End: 853507

Strand: Direct

Name: nudL [H]

Synonym: Rpic_0808

Alternate gene names: 187927903

Gene position: 852803-853507 (Clockwise)

Preceding gene: 187927902

Following gene: 187927904

Centisome position: 21.63

GC content: 63.97

Gene sequence:

>705_bases
ATGCGCCGTCCCGTGTTCGACCCTGAGCAGTTACCGGTGGTGCCGACCGAGGCATCATTGCCGGCGCTCGGGCTCCCGCG
GCTGACCGCCGAGTTCGTGCGCGAGCGGCTGCAGACGCAGCCCGACTGGCAACCGGAACAGACGGACGAATCCCGCCTGA
TCGACGCTTCGCTCAAGTTGCGCGAGGCGGCGGTGCTGGTGCCGCTGGTGCAGCGCGAGGCGGGTCTGACGGTGCTGCTG
ACGCAACGCAATGCATCGCTTAGCCAACATGCCGGCCAGGTCAGCTTTCCGGGCGGTGGACGCGAAGAATTTGACCGTGA
CATGGTCGACACGGCGCTGCGCGAGACGATGGAAGAGGTCGGCATTAGTGCCGAACACATCGAAGTGATCGGTCGCTTGC
CCGACTACATCACCGGGACCGGTTTCCATGTGAGCCCAATTGTCGGATTGCTCGCGCCCGATTTCACGCTGCAACCCGAC
CCAAGTGAAGTGGCGGAGGTGTTTGAAGTGCCGCTGGCCTTTTTGATGGATCCGGCCAACCACGAAGTGCGCGAGCTGCG
GTGGGAAGACCGCGTGCGTCGTTTCTATGCGATGCCTTACCGGCGATCTGGGCGATCTGACCAAGCGCCTGACTCTGGCC
ACCACTTCATCTGGGGCGCGACGGCGGGCATGCTGCGCAACCTGTATCACCTGCTGGCAGCGTAG

Upstream 100 bases:

>100_bases
CGCGTTGCGAAAAGGCACCTTCGGGTGCCTTTTTTCTCTTCTGCGGCGGAAGATTGACCCCATCTATGTCTTCCGCCCTC
GACTCATTCATTCCCATCGT

Downstream 100 bases:

>100_bases
CGCCGACGCGAATATGGGCACCCTGTGCGCTGTTGCGCGCACGCTGTGTGCTATCGTCTTGCACATCGCATTCACGGTGT
GATCCACGCCTTCGCAACGC

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRRPVFDPEQLPVVPTEASLPALGLPRLTAEFVRERLQTQPDWQPEQTDESRLIDASLKLREAAVLVPLVQREAGLTVLL
TQRNASLSQHAGQVSFPGGGREEFDRDMVDTALRETMEEVGISAEHIEVIGRLPDYITGTGFHVSPIVGLLAPDFTLQPD
PSEVAEVFEVPLAFLMDPANHEVRELRWEDRVRRFYAMPYRRSGRSDQAPDSGHHFIWGATAGMLRNLYHLLAA

Sequences:

>Translated_234_residues
MRRPVFDPEQLPVVPTEASLPALGLPRLTAEFVRERLQTQPDWQPEQTDESRLIDASLKLREAAVLVPLVQREAGLTVLL
TQRNASLSQHAGQVSFPGGGREEFDRDMVDTALRETMEEVGISAEHIEVIGRLPDYITGTGFHVSPIVGLLAPDFTLQPD
PSEVAEVFEVPLAFLMDPANHEVRELRWEDRVRRFYAMPYRRSGRSDQAPDSGHHFIWGATAGMLRNLYHLLAA
>Mature_234_residues
MRRPVFDPEQLPVVPTEASLPALGLPRLTAEFVRERLQTQPDWQPEQTDESRLIDASLKLREAAVLVPLVQREAGLTVLL
TQRNASLSQHAGQVSFPGGGREEFDRDMVDTALRETMEEVGISAEHIEVIGRLPDYITGTGFHVSPIVGLLAPDFTLQPD
PSEVAEVFEVPLAFLMDPANHEVRELRWEDRVRRFYAMPYRRSGRSDQAPDSGHHFIWGATAGMLRNLYHLLAA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=127, Percent_Identity=40.9448818897638, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1788115, Length=175, Percent_Identity=40, Blast_Score=99, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17536993, Length=179, Percent_Identity=34.6368715083799, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18859683, Length=175, Percent_Identity=34.8571428571429, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 26270; Mature: 26270

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPVFDPEQLPVVPTEASLPALGLPRLTAEFVRERLQTQPDWQPEQTDESRLIDASLKL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
REAAVLVPLVQREAGLTVLLTQRNASLSQHAGQVSFPGGGREEFDRDMVDTALRETMEEV
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GISAEHIEVIGRLPDYITGTGFHVSPIVGLLAPDFTLQPDPSEVAEVFEVPLAFLMDPAN
CCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
HEVRELRWEDRVRRFYAMPYRRSGRSDQAPDSGHHFIWGATAGMLRNLYHLLAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRPVFDPEQLPVVPTEASLPALGLPRLTAEFVRERLQTQPDWQPEQTDESRLIDASLKL
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
REAAVLVPLVQREAGLTVLLTQRNASLSQHAGQVSFPGGGREEFDRDMVDTALRETMEEV
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
GISAEHIEVIGRLPDYITGTGFHVSPIVGLLAPDFTLQPDPSEVAEVFEVPLAFLMDPAN
CCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
HEVRELRWEDRVRRFYAMPYRRSGRSDQAPDSGHHFIWGATAGMLRNLYHLLAA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA