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The map label for this gene is etfA [H]

Identifier: 187927890

GI number: 187927890

Start: 839978

End: 840913

Strand: Direct

Name: etfA [H]

Synonym: Rpic_0794

Alternate gene names: 187927890

Gene position: 839978-840913 (Clockwise)

Preceding gene: 187927889

Following gene: 187927891

Centisome position: 21.31

GC content: 66.24

Gene sequence:

>936_bases
ATGACCTCACTCGTTATTGCTGAACACGACAATCAAACCATCAAGGCCGCGACGCTGAACACCGTGACGGCAGCCGCCCA
ATGCGGCGGTGACGTCCACGTGTTGGTGGCCGGTGCTGGCTGCGGCGCCGCTGCACAGGCCGCTGCGCAAATAGCCGGCG
TGGCCAAGGTTCTGGTGGCCGACGCGCCCCAATTTGCCGATGGCCTGGCCGAGAACGTCGCCGAACAGGCCCTGGCCATT
GCCGGCAACTACAGCCACATCCTGGCGCCCGCCACCGCCTACGGCAAGAACATCCTGCCGCGTGTGGCCGCCAAGCTGGA
CGTGGCCCAGCTGTCCGACATCACCAAGGTCGACGGCCCGGACACCTTCGAGCGCCCGATCTACGCCGGCAACGCAATTG
CCACCGTGCAATCGGCCGACAAGGTGAAGGTGATCACCGTGCGCGGCACGGCATTCGACCCGGCTGCCGCGACCGGTGGT
TCGGCTGCTACCGAAAACCTGACCGCCGTGGCTGACACCGGCATCTCGCAATTCGTTTCGCGCGAAGTGACGAAGAGCGA
CCGCCCGGAACTGACCGCCGCGAAGATCATCGTGTCGGGCGGCCGTGGCGTGGGCTCGGGCGAGAACTACACCAAGGTGC
TGACGCCGCTGGCCGACAAGCTGGGCGCCGCGCTAGGTGCTTCGCGCGCGGCAGTGGACGCCGGCTTCGTGCCGAACGAC
TACCAGGTCGGCCAGACCGGCAAGATCGTCGCGCCGCAGCTGTACATCGCCGTCGGTATTTCGGGCGCAATCCAGCACTT
GGCCGGCATGAAGGATTCCAAGGTGATCGTCGCGATCAACAAGGATCCGGAAGCGCCGATCTTCCAGGTGGCGGACTACG
GCCTCGTGGGCGACCTGAATGCCGTCGTGCCGGAGCTGGTGGCCGCACTGGGCTGA

Upstream 100 bases:

>100_bases
TGTGGCCACGCTGGTCGCCAAGCTCAAGACCGAAGCGAAGGTGCTGTAAGCGGTCTCCTGACTGCAAGCAACTTCAAGCA
CACCGAACAGGCAGATCAAG

Downstream 100 bases:

>100_bases
TCGCACCGCGCAGCGCGCTTGGTTTGACGTGCGCTGCAATGCCCGACGCAAAGCCGTTTCCGACCTGTTTGGAAACGGCT
TTTTTATACGCGAGCGCCAT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTSLVIAEHDNQTIKAATLNTVTAAAQCGGDVHVLVAGAGCGAAAQAAAQIAGVAKVLVADAPQFADGLAENVAEQALAI
AGNYSHILAPATAYGKNILPRVAAKLDVAQLSDITKVDGPDTFERPIYAGNAIATVQSADKVKVITVRGTAFDPAAATGG
SAATENLTAVADTGISQFVSREVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLNAVVPELVAALG

Sequences:

>Translated_311_residues
MTSLVIAEHDNQTIKAATLNTVTAAAQCGGDVHVLVAGAGCGAAAQAAAQIAGVAKVLVADAPQFADGLAENVAEQALAI
AGNYSHILAPATAYGKNILPRVAAKLDVAQLSDITKVDGPDTFERPIYAGNAIATVQSADKVKVITVRGTAFDPAAATGG
SAATENLTAVADTGISQFVSREVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLNAVVPELVAALG
>Mature_310_residues
TSLVIAEHDNQTIKAATLNTVTAAAQCGGDVHVLVAGAGCGAAAQAAAQIAGVAKVLVADAPQFADGLAENVAEQALAIA
GNYSHILAPATAYGKNILPRVAAKLDVAQLSDITKVDGPDTFERPIYAGNAIATVQSADKVKVITVRGTAFDPAAATGGS
AATENLTAVADTGISQFVSREVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPNDY
QVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLNAVVPELVAALG

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=311, Percent_Identity=62.379421221865, Blast_Score=377, Evalue=1e-105,
Organism=Homo sapiens, GI189181759, Length=270, Percent_Identity=64.0740740740741, Blast_Score=335, Evalue=4e-92,
Organism=Escherichia coli, GI1786226, Length=231, Percent_Identity=37.2294372294372, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1787990, Length=255, Percent_Identity=34.5098039215686, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87082157, Length=243, Percent_Identity=33.7448559670782, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17506929, Length=312, Percent_Identity=56.7307692307692, Blast_Score=338, Evalue=2e-93,
Organism=Saccharomyces cerevisiae, GI6325261, Length=272, Percent_Identity=46.3235294117647, Blast_Score=249, Evalue=3e-67,
Organism=Drosophila melanogaster, GI17136898, Length=313, Percent_Identity=63.258785942492, Blast_Score=372, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24652801, Length=313, Percent_Identity=63.258785942492, Blast_Score=372, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31248; Mature: 31117

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLVIAEHDNQTIKAATLNTVTAAAQCGGDVHVLVAGAGCGAAAQAAAQIAGVAKVLVA
CCEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
DAPQFADGLAENVAEQALAIAGNYSHILAPATAYGKNILPRVAAKLDVAQLSDITKVDGP
CCCHHHHHHHHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DTFERPIYAGNAIATVQSADKVKVITVRGTAFDPAAATGGSAATENLTAVADTGISQFVS
CCCCCCEECCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHH
REVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
HHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLN
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCHH
AVVPELVAALG
HHHHHHHHHCC
>Mature Secondary Structure 
TSLVIAEHDNQTIKAATLNTVTAAAQCGGDVHVLVAGAGCGAAAQAAAQIAGVAKVLVA
CEEEEEECCCCEEEEEEHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHH
DAPQFADGLAENVAEQALAIAGNYSHILAPATAYGKNILPRVAAKLDVAQLSDITKVDGP
CCCHHHHHHHHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DTFERPIYAGNAIATVQSADKVKVITVRGTAFDPAAATGGSAATENLTAVADTGISQFVS
CCCCCCEECCCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHH
REVTKSDRPELTAAKIIVSGGRGVGSGENYTKVLTPLADKLGAALGASRAAVDAGFVPND
HHHCCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCC
YQVGQTGKIVAPQLYIAVGISGAIQHLAGMKDSKVIVAINKDPEAPIFQVADYGLVGDLN
CEECCCCCEECCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCCCCCCHH
AVVPELVAALG
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]