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The map label for this gene is fadE25 [H]

Identifier: 187927891

GI number: 187927891

Start: 841082

End: 842866

Strand: Direct

Name: fadE25 [H]

Synonym: Rpic_0795

Alternate gene names: 187927891

Gene position: 841082-842866 (Clockwise)

Preceding gene: 187927890

Following gene: 187927893

Centisome position: 21.33

GC content: 64.65

Gene sequence:

>1785_bases
ATGACCTATCAAGCCCCAGTCAAGGACATGCTGTTCGTGATGAACGAGTTGGCCGGCCTGGACAACGTCGCGAAGCTGCC
TGGCTTTGAAGACGCCACCGCCGACACGGCGCAGGCCGTGCTGGAAGAAAGCGCCCGCTTTACTGGCGAAGTCGTTGCGC
CGCTGAATGTGGAAGGCGACCGTAACCCGAGCAGTTGGAAGGACGGCGTCGTCACGGCCACCGCAGGTTTCAAGGAGGCG
TTCGCGCAGTTCGGCCAAGGCGGCTGGCAGGGCGTGCAGCATCCGCTGGAATACGGCGGCCAGGGCCTGCCCAAGCTGAT
CGCCACGGCGTGTATCGAAATGCTGAACGCGGCCAACCTGTCGTTCGCACTGTGCCCGTTGCTGACGGATGGCGCCATTG
AGGCATTGCTGACGGCCGGCACCGAAGAACAGAAGCAGCTTTTCGTCCCCAAGCTCATCTCGGGCGAATGGACGGGCACG
ATGAACCTGACCGAGCCGCAGGCCGGCTCCGACCTGGCACTCGTGCGCACGCGCGCCGAGCCGGTGGGCGACGGCACGTT
CAAGATCTTCGGTACAAAGATCTTCATCACCTGGGGCGAGCACGATATGGCCGAGAACATCGTCCACCTCGTGCTGGCGC
GTACGCCGGGCGCGCCGGAAGGCGTCAAGGGCATATCGCTGTTTGTGGTGCCGAAGTTCATGGTCAATGAAGATGGCTCG
CTGGGCGCGCGCAACGATGCGCATTGCGTATCGATCGAACATAAGCTCGGCATCAAGGCGAGCCCGACGGCCGTGCTGCA
ATTTGGCGATAACGGCGGCGCGATCGGGACGCTGGTCGGCGAAGAAAATCGCGGCCTGGAATACATGTTCATCATGATGA
ACGCGGCGCGTTATGCGGTCGGCATGCAGGGCATTGGCGTGTCGGAGCGCGCTTACCAAAAGGCCGTGGCCTATGCGCGT
GACCGCGTGCAGAGCCGCCCGGTGGATGGCTCTGCTGCCAAAGCTGTGCCCATCATTCACCACCCGGATGTGAAGCGCAT
GCTGCTGACGATGCGCGCCATGACCGAAGGCGCGCGTGCGCTGGCCTACGTGGCTGCCGCAGCGTGCGATGCCGGCCATC
ACGCTGCCGATGACGCAGCACGCAAGCAGAACGCGGCGCTGTACGAATTCCTGGTGCCGATCGTGAAGGGCTGGAGCACC
GAGATGTCGATCGACGTGACGAGCCTGGGCGTGCAGGTGCACGGCGGCATGGGCTTTATCGAAGAGACGGGCGCCGCGCA
GTTCTATCGTGATGCGCGCATCCTGCCGATCTACGAAGGCACCACGGCCATCCAGGCCAACGACCTGATCGGCCGCAAGA
CGGTGCGTGACGGGGGCGCGGTAGCCTCGGGCATCTGCGCGGAAATCGCCAAGGTGGAGGCGGCGCTCGCTGCGAAGGGC
GGTGCGCATTGCGATGCGATGCGTGCGCGTCTGGCAGCCGGTCGCGAGGCGCTGGAATCGGTGGTGCGCTTTGTGGTCGC
CCAGACCAAGGCGCAGCCGAACGCCGTCTTCGCAGGCAGCGTACCGTATCTGCGCCTGTGCGGCATCGTGCTGTCGGGCT
GGCAGATGGCGCGTGCGCTGCTGGTGGCGATCGACCGCGAGAGCGAAGACCCGAACTTCTACGGCGCGAAGATCGCCACG
GCACGCGTGTTTGCCGATGTGCTGCTCACGCAGGCACCTGGTATTGCGCAGAGTGTGCTGACGGGCGGCGAGACGATCGG
TGCGGTGCCGGAAGTCCTGTTCTGA

Upstream 100 bases:

>100_bases
TTGGAAACGGCTTTTTTATACGCGAGCGCCATCAGGAGAGCGCGTCACGCACTCGATGAGGCACTGTCCTGATCGCGCTT
AACCAGAGTTGGAGAGAGAC

Downstream 100 bases:

>100_bases
GCGGCATCAGCCGGAAAAAAAAAAGGGAGGCTCCTGCCTCCCTTTTTTATCGCATGCAGCGTAGGCGATCAGGCCAGCGC
AGGCTTGGTTGCCGGCATCT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MTYQAPVKDMLFVMNELAGLDNVAKLPGFEDATADTAQAVLEESARFTGEVVAPLNVEGDRNPSSWKDGVVTATAGFKEA
FAQFGQGGWQGVQHPLEYGGQGLPKLIATACIEMLNAANLSFALCPLLTDGAIEALLTAGTEEQKQLFVPKLISGEWTGT
MNLTEPQAGSDLALVRTRAEPVGDGTFKIFGTKIFITWGEHDMAENIVHLVLARTPGAPEGVKGISLFVVPKFMVNEDGS
LGARNDAHCVSIEHKLGIKASPTAVLQFGDNGGAIGTLVGEENRGLEYMFIMMNAARYAVGMQGIGVSERAYQKAVAYAR
DRVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARALAYVAAAACDAGHHAADDAARKQNAALYEFLVPIVKGWST
EMSIDVTSLGVQVHGGMGFIEETGAAQFYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVASGICAEIAKVEAALAAKG
GAHCDAMRARLAAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARALLVAIDRESEDPNFYGAKIAT
ARVFADVLLTQAPGIAQSVLTGGETIGAVPEVLF

Sequences:

>Translated_594_residues
MTYQAPVKDMLFVMNELAGLDNVAKLPGFEDATADTAQAVLEESARFTGEVVAPLNVEGDRNPSSWKDGVVTATAGFKEA
FAQFGQGGWQGVQHPLEYGGQGLPKLIATACIEMLNAANLSFALCPLLTDGAIEALLTAGTEEQKQLFVPKLISGEWTGT
MNLTEPQAGSDLALVRTRAEPVGDGTFKIFGTKIFITWGEHDMAENIVHLVLARTPGAPEGVKGISLFVVPKFMVNEDGS
LGARNDAHCVSIEHKLGIKASPTAVLQFGDNGGAIGTLVGEENRGLEYMFIMMNAARYAVGMQGIGVSERAYQKAVAYAR
DRVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARALAYVAAAACDAGHHAADDAARKQNAALYEFLVPIVKGWST
EMSIDVTSLGVQVHGGMGFIEETGAAQFYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVASGICAEIAKVEAALAAKG
GAHCDAMRARLAAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARALLVAIDRESEDPNFYGAKIAT
ARVFADVLLTQAPGIAQSVLTGGETIGAVPEVLF
>Mature_593_residues
TYQAPVKDMLFVMNELAGLDNVAKLPGFEDATADTAQAVLEESARFTGEVVAPLNVEGDRNPSSWKDGVVTATAGFKEAF
AQFGQGGWQGVQHPLEYGGQGLPKLIATACIEMLNAANLSFALCPLLTDGAIEALLTAGTEEQKQLFVPKLISGEWTGTM
NLTEPQAGSDLALVRTRAEPVGDGTFKIFGTKIFITWGEHDMAENIVHLVLARTPGAPEGVKGISLFVVPKFMVNEDGSL
GARNDAHCVSIEHKLGIKASPTAVLQFGDNGGAIGTLVGEENRGLEYMFIMMNAARYAVGMQGIGVSERAYQKAVAYARD
RVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARALAYVAAAACDAGHHAADDAARKQNAALYEFLVPIVKGWSTE
MSIDVTSLGVQVHGGMGFIEETGAAQFYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVASGICAEIAKVEAALAAKGG
AHCDAMRARLAAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARALLVAIDRESEDPNFYGAKIATA
RVFADVLLTQAPGIAQSVLTGGETIGAVPEVLF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=424, Percent_Identity=27.5943396226415, Blast_Score=123, Evalue=6e-28,
Organism=Homo sapiens, GI4501857, Length=383, Percent_Identity=28.9817232375979, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI4501859, Length=407, Percent_Identity=27.2727272727273, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI226958414, Length=377, Percent_Identity=28.6472148541114, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4557233, Length=361, Percent_Identity=31.0249307479224, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4557235, Length=418, Percent_Identity=29.6650717703349, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI76496475, Length=418, Percent_Identity=29.6650717703349, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=26.1904761904762, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI7656849, Length=373, Percent_Identity=27.3458445040214, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI187960098, Length=316, Percent_Identity=25.6329113924051, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4557231, Length=316, Percent_Identity=25.6329113924051, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI87082384, Length=358, Percent_Identity=27.0949720670391, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI87081958, Length=367, Percent_Identity=25.6130790190736, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508101, Length=409, Percent_Identity=30.5623471882641, Blast_Score=141, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17506239, Length=405, Percent_Identity=29.6296296296296, Blast_Score=126, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI86563381, Length=339, Percent_Identity=28.023598820059, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI86563383, Length=339, Percent_Identity=28.023598820059, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=384, Percent_Identity=27.8645833333333, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=360, Percent_Identity=26.6666666666667, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=415, Percent_Identity=26.7469879518072, Blast_Score=101, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=390, Percent_Identity=27.4358974358974, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=425, Percent_Identity=25.6470588235294, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17570075, Length=386, Percent_Identity=26.6839378238342, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17505929, Length=420, Percent_Identity=26.6666666666667, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=282, Percent_Identity=28.0141843971631, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=26.158038147139, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=242, Percent_Identity=31.404958677686, Blast_Score=89, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=258, Percent_Identity=29.4573643410853, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=299, Percent_Identity=26.4214046822742, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356377, Length=373, Percent_Identity=30.2949061662198, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI21355753, Length=451, Percent_Identity=27.9379157427938, Blast_Score=112, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281363737, Length=364, Percent_Identity=27.4725274725275, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24666513, Length=366, Percent_Identity=27.3224043715847, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24660351, Length=361, Percent_Identity=27.9778393351801, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=25.9459459459459, Blast_Score=91, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 62806; Mature: 62674

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQAPVKDMLFVMNELAGLDNVAKLPGFEDATADTAQAVLEESARFTGEVVAPLNVEGD
CCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCC
RNPSSWKDGVVTATAGFKEAFAQFGQGGWQGVQHPLEYGGQGLPKLIATACIEMLNAANL
CCCCCCCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALLTAGTEEQKQLFVPKLISGEWTGTMNLTEPQAGSDLALVRTRAE
CEEEHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCCEEECCCCCCCCCEEEEEECCC
PVGDGTFKIFGTKIFITWGEHDMAENIVHLVLARTPGAPEGVKGISLFVVPKFMVNEDGS
CCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHEECCCCC
LGARNDAHCVSIEHKLGIKASPTAVLQFGDNGGAIGTLVGEENRGLEYMFIMMNAARYAV
CCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEHHHHHHH
GMQGIGVSERAYQKAVAYARDRVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LAYVAAAACDAGHHAADDAARKQNAALYEFLVPIVKGWSTEMSIDVTSLGVQVHGGMGFI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCH
EETGAAQFYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVASGICAEIAKVEAALAAKG
HHCCCHHHHHCCEEEEEECCCCEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCC
GAHCDAMRARLAAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
LVAIDRESEDPNFYGAKIATARVFADVLLTQAPGIAQSVLTGGETIGAVPEVLF
HHHEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHCCCHHHCC
>Mature Secondary Structure 
TYQAPVKDMLFVMNELAGLDNVAKLPGFEDATADTAQAVLEESARFTGEVVAPLNVEGD
CCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCC
RNPSSWKDGVVTATAGFKEAFAQFGQGGWQGVQHPLEYGGQGLPKLIATACIEMLNAANL
CCCCCCCCCEEEEECCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALLTAGTEEQKQLFVPKLISGEWTGTMNLTEPQAGSDLALVRTRAE
CEEEHHHHHHHHHHHHHHCCCCHHHHHHCCHHHCCCCCCEEECCCCCCCCCEEEEEECCC
PVGDGTFKIFGTKIFITWGEHDMAENIVHLVLARTPGAPEGVKGISLFVVPKFMVNEDGS
CCCCCEEEEEEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHEECCCCC
LGARNDAHCVSIEHKLGIKASPTAVLQFGDNGGAIGTLVGEENRGLEYMFIMMNAARYAV
CCCCCCCEEEEEHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEHHHHHHH
GMQGIGVSERAYQKAVAYARDRVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LAYVAAAACDAGHHAADDAARKQNAALYEFLVPIVKGWSTEMSIDVTSLGVQVHGGMGFI
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCCCCH
EETGAAQFYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVASGICAEIAKVEAALAAKG
HHCCCHHHHHCCEEEEEECCCCEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHCC
GAHCDAMRARLAAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
LVAIDRESEDPNFYGAKIATARVFADVLLTQAPGIAQSVLTGGETIGAVPEVLF
HHHEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCHHCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]