Click here to switch to the map view.

The map label for this gene is ubiG [H]

Identifier: 187927864

GI number: 187927864

Start: 812389

End: 813120

Strand: Reverse

Name: ubiG [H]

Synonym: Rpic_0768

Alternate gene names: 187927864

Gene position: 813120-812389 (Counterclockwise)

Preceding gene: 187927866

Following gene: 187927863

Centisome position: 20.62

GC content: 63.25

Gene sequence:

>732_bases
ATGGCGCAGCGCAACATGACGACCACTCACGCGAACGCCGATCCCGGCGAACTCGAAAAATTCAGCGAACTCGCCCACCG
CTGGTGGGATCCGAACAGCGAGTTCAAACCCCTGCACGAAATCAATCCGCTGCGCCTCGGCTGGATTCAGTCGATCGCCC
CGCTGGCCGGCAAACGCATCGTCGACGTGGGCTGCGGCGGCGGCATCCTTTCAGAGAGCATGGCGCGTGCCGGCGCCGAC
GTCAAAGGCATCGACCTGTCCCGCAAAGCGCTGCGTGTCGCCGACCTGCATAGTCTCGAGGCGGGCGTTACCGTCGATTA
CGAGGAGATTGCCGCAGAAGCCTTGGCCGCACGCGAGCCGGCCAGCTTCGATGTCGTTACTTGCATGGAGATGCTCGAAC
ATGTGCCCGATCCGGCGTCTGTTGTGCGTGCGTGCGCGACGCTGGTAAAACCGGGCGGATACGTGTTTTTCTCGACCATC
CACCGGAACGCCAAGGCCTATCTGCTGGCGGTCATTGGCGCGGAATACGTGCTCAACATGCTGCCGCGCGGCACGCATGA
CTACGCCAAGTTCATTCGCCCGTCGGAGCTGAGCGCGTTCGTACGGGGGGCCGGGCTCCAGGCTCAAGAGATGTGCGGGC
TCGAATACAACCCGATCACCGGCCGCTATGCCCTCACGCAGGACGCCAGCGTCAACTATTTGATGGCAACGCGCCGTCCG
GCCGAGGCATGA

Upstream 100 bases:

>100_bases
CGTTTGTTCACCTCTGTTTCAATGTGAAACCTTTTCGCAAACCCCTTGATTTGGTTGGGGCGACGCTTTTTGGTACATTT
CCTCACCTAGCCGATATGCC

Downstream 100 bases:

>100_bases
CGGCGCGCCAGTTTCCCGATCCGCTGGGCGCGGTGCTGTTCGACCTGGACGGCACACTTGCGGACACGGCCCCCGATCTG
GCCGCCGCGGCCAACAAGGT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MAQRNMTTTHANADPGELEKFSELAHRWWDPNSEFKPLHEINPLRLGWIQSIAPLAGKRIVDVGCGGGILSESMARAGAD
VKGIDLSRKALRVADLHSLEAGVTVDYEEIAAEALAAREPASFDVVTCMEMLEHVPDPASVVRACATLVKPGGYVFFSTI
HRNAKAYLLAVIGAEYVLNMLPRGTHDYAKFIRPSELSAFVRGAGLQAQEMCGLEYNPITGRYALTQDASVNYLMATRRP
AEA

Sequences:

>Translated_243_residues
MAQRNMTTTHANADPGELEKFSELAHRWWDPNSEFKPLHEINPLRLGWIQSIAPLAGKRIVDVGCGGGILSESMARAGAD
VKGIDLSRKALRVADLHSLEAGVTVDYEEIAAEALAAREPASFDVVTCMEMLEHVPDPASVVRACATLVKPGGYVFFSTI
HRNAKAYLLAVIGAEYVLNMLPRGTHDYAKFIRPSELSAFVRGAGLQAQEMCGLEYNPITGRYALTQDASVNYLMATRRP
AEA
>Mature_242_residues
AQRNMTTTHANADPGELEKFSELAHRWWDPNSEFKPLHEINPLRLGWIQSIAPLAGKRIVDVGCGGGILSESMARAGADV
KGIDLSRKALRVADLHSLEAGVTVDYEEIAAEALAAREPASFDVVTCMEMLEHVPDPASVVRACATLVKPGGYVFFSTIH
RNAKAYLLAVIGAEYVLNMLPRGTHDYAKFIRPSELSAFVRGAGLQAQEMCGLEYNPITGRYALTQDASVNYLMATRRPA
EA

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=244, Percent_Identity=34.0163934426229, Blast_Score=174, Evalue=6e-44,
Organism=Escherichia coli, GI1788564, Length=229, Percent_Identity=56.7685589519651, Blast_Score=278, Evalue=2e-76,
Organism=Caenorhabditis elegans, GI115533050, Length=234, Percent_Identity=34.1880341880342, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324476, Length=290, Percent_Identity=31.0344827586207, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281365311, Length=266, Percent_Identity=30.0751879699248, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24585589, Length=233, Percent_Identity=33.4763948497854, Blast_Score=126, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 26486; Mature: 26354

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRNMTTTHANADPGELEKFSELAHRWWDPNSEFKPLHEINPLRLGWIQSIAPLAGKRI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCEE
VDVGCGGGILSESMARAGADVKGIDLSRKALRVADLHSLEAGVTVDYEEIAAEALAAREP
EEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHCCC
ASFDVVTCMEMLEHVPDPASVVRACATLVKPGGYVFFSTIHRNAKAYLLAVIGAEYVLNM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHH
LPRGTHDYAKFIRPSELSAFVRGAGLQAQEMCGLEYNPITGRYALTQDASVNYLMATRRP
CCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEECCCCCCEEEEECCCC
AEA
CCC
>Mature Secondary Structure 
AQRNMTTTHANADPGELEKFSELAHRWWDPNSEFKPLHEINPLRLGWIQSIAPLAGKRI
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCHHHHHHHHHHHCCCEE
VDVGCGGGILSESMARAGADVKGIDLSRKALRVADLHSLEAGVTVDYEEIAAEALAAREP
EEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHCCC
ASFDVVTCMEMLEHVPDPASVVRACATLVKPGGYVFFSTIHRNAKAYLLAVIGAEYVLNM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHHHHHH
LPRGTHDYAKFIRPSELSAFVRGAGLQAQEMCGLEYNPITGRYALTQDASVNYLMATRRP
CCCCCHHHHHHCCHHHHHHHHHCCCCCHHHHCCCCCCCCCCCEEECCCCCCEEEEECCCC
AEA
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]