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The map label for this gene is ecpD [H]

Identifier: 187927858

GI number: 187927858

Start: 802755

End: 803501

Strand: Direct

Name: ecpD [H]

Synonym: Rpic_0762

Alternate gene names: 187927858

Gene position: 802755-803501 (Clockwise)

Preceding gene: 187927857

Following gene: 187927859

Centisome position: 20.36

GC content: 60.11

Gene sequence:

>747_bases
ATGAAAGCAAAACGATTCGCCGTTGGCGCGGCGTTGGCGTGCGCGTTGGCTGCGTCCGCGAGTCACGCCAGTATTTCCTT
AGGTACTACGCGGGTGATCTTTGATGGCAAGAACAAGGAAAGCTCCGTGGTCGTCATCAACGATGGCGCCGATGCACTGA
TCCAGTCGTGGCTGGATCCGCTCGATGACGTTGCCCATACGCAACTGCCGTTTGCTATTACACCGCCGTTAGCCAAGGTC
GGGGCCAAGCAGCAGCAACTGTTGCGCGTACTGTATGAAGGCGTGGGCATGCCCGCCGACCGAGAGTCCGCCTTCTGGCT
GAACGTGCAGGAAATCCCACAAGCAGCGAGCAAAGACAACGTGCTGCAACTCGCTGTGCGCCAGCGCATCAAGGTGTTCT
ATCGGCCCGTTGGTTTGGGCGGTGATCCTCTCAAAGCGGCCACCAGTCTGCAATGGCAACTGAATCAAGACGCCGGTAAG
GCAATGCTGCGGCTGACCAACCCGAGCCTCTATCACGTGACCGTAGTGGACGCCAAGCTCCACACCGGAAACAAGGATGA
ACCGGTCGTTGACGCCAAGATGATCGCGCCAGGTTCCACGGTGGCCTTGCCCGTCAATGTGCCGGCCGGGCACACCGGCG
CACCGGAGCTGCGCTACGAAGTCATCAATGACTTCGGCGGACGCGAAAGCTACCGCGTCACCCTGCAAGGCAATCAGCCG
AGCGCGCCGGTATCCGCCGGTAACTGA

Upstream 100 bases:

>100_bases
GCTGAGCTACGAGTAAGCCAAGCGCCAGCCACCCAGGGCTGGCTTCAATCGGCAGCGGCGCTTGTCCGCTGCCACCTCTT
TCTTCAAGGCAATTCCGGAT

Downstream 100 bases:

>100_bases
TCGACCTAGTCGAGTTCTTCTATCCAGCCTGCAGTGGTTGGATTAGCCCGCGCCCCTTCGAAGCGGAGCTTGCCCATGTG
ACACCCCTGATTCTCAAGGC

Product: Pili assembly chaperone, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKAKRFAVGAALACALAASASHASISLGTTRVIFDGKNKESSVVVINDGADALIQSWLDPLDDVAHTQLPFAITPPLAKV
GAKQQQLLRVLYEGVGMPADRESAFWLNVQEIPQAASKDNVLQLAVRQRIKVFYRPVGLGGDPLKAATSLQWQLNQDAGK
AMLRLTNPSLYHVTVVDAKLHTGNKDEPVVDAKMIAPGSTVALPVNVPAGHTGAPELRYEVINDFGGRESYRVTLQGNQP
SAPVSAGN

Sequences:

>Translated_248_residues
MKAKRFAVGAALACALAASASHASISLGTTRVIFDGKNKESSVVVINDGADALIQSWLDPLDDVAHTQLPFAITPPLAKV
GAKQQQLLRVLYEGVGMPADRESAFWLNVQEIPQAASKDNVLQLAVRQRIKVFYRPVGLGGDPLKAATSLQWQLNQDAGK
AMLRLTNPSLYHVTVVDAKLHTGNKDEPVVDAKMIAPGSTVALPVNVPAGHTGAPELRYEVINDFGGRESYRVTLQGNQP
SAPVSAGN
>Mature_248_residues
MKAKRFAVGAALACALAASASHASISLGTTRVIFDGKNKESSVVVINDGADALIQSWLDPLDDVAHTQLPFAITPPLAKV
GAKQQQLLRVLYEGVGMPADRESAFWLNVQEIPQAASKDNVLQLAVRQRIKVFYRPVGLGGDPLKAATSLQWQLNQDAGK
AMLRLTNPSLYHVTVVDAKLHTGNKDEPVVDAKMIAPGSTVALPVNVPAGHTGAPELRYEVINDFGGRESYRVTLQGNQP
SAPVSAGN

Specific function: Probably mediates assembly of a pilin [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1786333, Length=226, Percent_Identity=39.8230088495575, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI1789532, Length=234, Percent_Identity=34.1880341880342, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1790771, Length=220, Percent_Identity=34.5454545454545, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786743, Length=220, Percent_Identity=32.7272727272727, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1787171, Length=221, Percent_Identity=31.6742081447964, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788428, Length=220, Percent_Identity=32.2727272727273, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1788677, Length=213, Percent_Identity=31.4553990610329, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786936, Length=232, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI87082203, Length=235, Percent_Identity=26.8085106382979, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI87081806, Length=180, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 26394; Mature: 26394

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKRFAVGAALACALAASASHASISLGTTRVIFDGKNKESSVVVINDGADALIQSWLDP
CCCCHHHHHHHHHHHHHHCCCCCEEEECEEEEEEECCCCCCEEEEEECCHHHHHHHHHHH
LDDVAHTQLPFAITPPLAKVGAKQQQLLRVLYEGVGMPADRESAFWLNVQEIPQAASKDN
HHHHHHCCCCEEECCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCCCCCH
VLQLAVRQRIKVFYRPVGLGGDPLKAATSLQWQLNQDAGKAMLRLTNPSLYHVTVVDAKL
HHHHHHHHHHHHHEEECCCCCCCCCHHEEEEEEECCCCCCEEEEECCCCEEEEEEEEEEE
HTGNKDEPVVDAKMIAPGSTVALPVNVPAGHTGAPELRYEVINDFGGRESYRVTLQGNQP
CCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCC
SAPVSAGN
CCCCCCCC
>Mature Secondary Structure
MKAKRFAVGAALACALAASASHASISLGTTRVIFDGKNKESSVVVINDGADALIQSWLDP
CCCCHHHHHHHHHHHHHHCCCCCEEEECEEEEEEECCCCCCEEEEEECCHHHHHHHHHHH
LDDVAHTQLPFAITPPLAKVGAKQQQLLRVLYEGVGMPADRESAFWLNVQEIPQAASKDN
HHHHHHCCCCEEECCCHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEEEHHHHCCCCCCCH
VLQLAVRQRIKVFYRPVGLGGDPLKAATSLQWQLNQDAGKAMLRLTNPSLYHVTVVDAKL
HHHHHHHHHHHHHEEECCCCCCCCCHHEEEEEEECCCCCCEEEEECCCCEEEEEEEEEEE
HTGNKDEPVVDAKMIAPGSTVALPVNVPAGHTGAPELRYEVINDFGGRESYRVTLQGNQP
CCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCC
SAPVSAGN
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8102362; 8202364; 9278503 [H]