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The map label for this gene is ttuB [H]

Identifier: 187927787

GI number: 187927787

Start: 729010

End: 730290

Strand: Direct

Name: ttuB [H]

Synonym: Rpic_0691

Alternate gene names: 187927787

Gene position: 729010-730290 (Clockwise)

Preceding gene: 187927786

Following gene: 187927788

Centisome position: 18.49

GC content: 62.37

Gene sequence:

>1281_bases
ATGGCAACGCAACTGGCTGCGCGGCGCTGGTGGATGATCATGCCGATCGTCTTTATCACCTACAGCCTGGCCTACCTCGA
TCGCGCGAACTATGGCTTCGCGGCGGCGGCCGGCATCAATCACGATCTGGGGATCAGCCAGGGGCTGTCGTCGTTGATTG
GCGCGCTGTTTTTCCTCGGCTATTTCTTCTTCCAGATTCCCGGCGCGATCTACGCAGAGCGCCGCAGCGTGAAGAAACTC
GTGTTCATCAGCCTCGTGTTGTGGGGCTTGTGTGCGGCGCTCACGGGCGTCGTGAGTGACATTCCCTCGTTGATGGCGAT
CCGGTTTGTGCTGGGTGTGGTCGAGGCGGCCGTCATGCCGGCGATGCTCATCTACATCAGCAACTGGTTTACCAAGCACG
AGCGTTCGCGCGCGAATACGTTCCTGATTCTGGGCAATCCCGTGACCGTGCTCTGGATGTCGGTGGTATCGGGCTACCTC
GTGCGCGAGTTCGGCTGGCGCCATATGTTCATCGCCGAGGGCGTGCCCGCCATCATCTGGGCCGTGTGCTGGTGGTGCCT
GGTGCAGGACAAGCCCGCGCAGGCGCCGTGGCTGAACCCACAGGAAAAGCGCGACCTGGAACAAGCCTTGGCGACGGAAC
AGGCGGCCATCAAGCCGATGCGCAACTATGGCGAGGCCTTCCGCTCGCCTGTCGTCATCAAGCTGTGCGCGCAGTACTTC
TGCTGGAGCATCGGCGTCTATGGTTTCGTGCTATGGCTACCGTCCATCGTGAAGAACGGCTCGTCGCTTGGCATGGTCGA
GACGGGTTGGCTGTCGGCGCTGCCGTATCTGGCGGCCACCATCGCGATGCTCGCGGCGTCGTGGGCATCCGACAAGGTGG
GGTCGCGGCGTGGGTTCGTCTGGCCGTTCCTGCTGGTGGGGGCCGCAGCGTTTGCCGCATCGTTTGCACTCGGCTCAACG
CATTTCTGGATGTCGTATGTGCTGCTCGTGATTGCCGGTGCGGCGATGTATGCACCGTATGGTCCGTTCTTCGCGATCGT
GCCGGAGCTTCTGCCTAAGAACGTCGCCGGTGGCGCGATGGCGCTGATCAACAGCATGGGCGCTCTCGGTTCGTTTGTCG
GCTCGTACTTCGTTGGCTACCTGAACGGTGCCACCGGCTCGCCGCTGGCGTCGTACGCTTTCATGAGCGCCGCGCTCCTC
GCAGCCGTAGTGCTTACGCTTTGCGTCAAGCCGCAACCGCGTGATGCGTACACGCTCGCCCACCCTGTGCCTGGAAAATG
A

Upstream 100 bases:

>100_bases
CCCGCATGGCATGCGAGCCGGAACCCATTTCCAACGTGTAACGCAGCGCTTCGACTGCCGCCCGTCACGGGCAACGCAAA
CCATCAAAGGAGACACGACC

Downstream 100 bases:

>100_bases
ACTGATGAAACCGCTTGTCGTTGCCTACAAGCCTTTGCCCGACGATGTCACGGCTCAGTTGCGCGAGCATGTCGAACTCG
TGCAGGTTGACGGTGCCGAG

Product: major facilitator superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MATQLAARRWWMIMPIVFITYSLAYLDRANYGFAAAAGINHDLGISQGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKL
VFISLVLWGLCAALTGVVSDIPSLMAIRFVLGVVEAAVMPAMLIYISNWFTKHERSRANTFLILGNPVTVLWMSVVSGYL
VREFGWRHMFIAEGVPAIIWAVCWWCLVQDKPAQAPWLNPQEKRDLEQALATEQAAIKPMRNYGEAFRSPVVIKLCAQYF
CWSIGVYGFVLWLPSIVKNGSSLGMVETGWLSALPYLAATIAMLAASWASDKVGSRRGFVWPFLLVGAAAFAASFALGST
HFWMSYVLLVIAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPLASYAFMSAALL
AAVVLTLCVKPQPRDAYTLAHPVPGK

Sequences:

>Translated_426_residues
MATQLAARRWWMIMPIVFITYSLAYLDRANYGFAAAAGINHDLGISQGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKL
VFISLVLWGLCAALTGVVSDIPSLMAIRFVLGVVEAAVMPAMLIYISNWFTKHERSRANTFLILGNPVTVLWMSVVSGYL
VREFGWRHMFIAEGVPAIIWAVCWWCLVQDKPAQAPWLNPQEKRDLEQALATEQAAIKPMRNYGEAFRSPVVIKLCAQYF
CWSIGVYGFVLWLPSIVKNGSSLGMVETGWLSALPYLAATIAMLAASWASDKVGSRRGFVWPFLLVGAAAFAASFALGST
HFWMSYVLLVIAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPLASYAFMSAALL
AAVVLTLCVKPQPRDAYTLAHPVPGK
>Mature_425_residues
ATQLAARRWWMIMPIVFITYSLAYLDRANYGFAAAAGINHDLGISQGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKLV
FISLVLWGLCAALTGVVSDIPSLMAIRFVLGVVEAAVMPAMLIYISNWFTKHERSRANTFLILGNPVTVLWMSVVSGYLV
REFGWRHMFIAEGVPAIIWAVCWWCLVQDKPAQAPWLNPQEKRDLEQALATEQAAIKPMRNYGEAFRSPVVIKLCAQYFC
WSIGVYGFVLWLPSIVKNGSSLGMVETGWLSALPYLAATIAMLAASWASDKVGSRRGFVWPFLLVGAAAFAASFALGSTH
FWMSYVLLVIAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPLASYAFMSAALLA
AVVLTLCVKPQPRDAYTLAHPVPGK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9945322, Length=253, Percent_Identity=25.296442687747, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI6912666, Length=245, Percent_Identity=24.4897959183673, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI9966811, Length=365, Percent_Identity=23.8356164383562, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI21322234, Length=259, Percent_Identity=26.6409266409266, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI148743791, Length=233, Percent_Identity=21.0300429184549, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87082071, Length=369, Percent_Identity=27.3712737127371, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87082320, Length=426, Percent_Identity=23.7089201877934, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1789515, Length=420, Percent_Identity=24.047619047619, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789152, Length=427, Percent_Identity=23.6533957845433, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI2367379, Length=281, Percent_Identity=24.1992882562278, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17552542, Length=318, Percent_Identity=25.4716981132075, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=362, Percent_Identity=24.8618784530387, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115533554, Length=362, Percent_Identity=24.8618784530387, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560030, Length=275, Percent_Identity=21.4545454545455, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17535049, Length=433, Percent_Identity=23.7875288683603, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17566884, Length=181, Percent_Identity=27.0718232044199, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86561091, Length=334, Percent_Identity=24.8502994011976, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141318, Length=334, Percent_Identity=24.8502994011976, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141316, Length=334, Percent_Identity=24.8502994011976, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=261, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25141341, Length=276, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI32565916, Length=176, Percent_Identity=23.8636363636364, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI32565914, Length=176, Percent_Identity=23.8636363636364, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=218, Percent_Identity=24.7706422018349, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24580790, Length=349, Percent_Identity=26.0744985673352, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24583789, Length=356, Percent_Identity=23.876404494382, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550460, Length=307, Percent_Identity=25.4071661237785, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24655255, Length=268, Percent_Identity=26.1194029850746, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24584153, Length=376, Percent_Identity=22.6063829787234, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI20130135, Length=393, Percent_Identity=22.9007633587786, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24655271, Length=400, Percent_Identity=22.75, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19922400, Length=306, Percent_Identity=22.5490196078431, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24654215, Length=306, Percent_Identity=22.5490196078431, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573299, Length=307, Percent_Identity=23.7785016286645, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24641682, Length=282, Percent_Identity=23.0496453900709, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573708, Length=272, Percent_Identity=23.8970588235294, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573707, Length=272, Percent_Identity=23.8970588235294, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI62484226, Length=241, Percent_Identity=28.2157676348548, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639764, Length=278, Percent_Identity=23.021582733813, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24648416, Length=272, Percent_Identity=23.1617647058824, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21356189, Length=272, Percent_Identity=23.1617647058824, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI20129235, Length=358, Percent_Identity=24.3016759776536, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653727, Length=373, Percent_Identity=24.3967828418231, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130167, Length=258, Percent_Identity=23.6434108527132, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46386; Mature: 46255

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCC
>Mature Secondary Structure 
ATQLAARRWWMIMPIVFITYSLAYLDRANYGFAAAAGINHDLGISQGLSSLIGALFFLG
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHH
YFFFQIPGAIYAERRSVKKLVFISLVLWGLCAALTGVVSDIPSLMAIRFVLGVVEAAVMP
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMLIYISNWFTKHERSRANTFLILGNPVTVLWMSVVSGYLVREFGWRHMFIAEGVPAIIW
HHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCEEHHHCCHHHHHH
AVCWWCLVQDKPAQAPWLNPQEKRDLEQALATEQAAIKPMRNYGEAFRSPVVIKLCAQYF
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
CWSIGVYGFVLWLPSIVKNGSSLGMVETGWLSALPYLAATIAMLAASWASDKVGSRRGFV
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
WPFLLVGAAAFAASFALGSTHFWMSYVLLVIAGAAMYAPYGPFFAIVPELLPKNVAGGAM
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHH
ALINSMGALGSFVGSYFVGYLNGATGSPLASYAFMSAALLAAVVLTLCVKPQPRDAYTLA
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEC
HPVPGK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]