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The map label for this gene is nrdR

Identifier: 187927773

GI number: 187927773

Start: 716349

End: 716813

Strand: Reverse

Name: nrdR

Synonym: Rpic_0677

Alternate gene names: 187927773

Gene position: 716813-716349 (Counterclockwise)

Preceding gene: 187927774

Following gene: 187927765

Centisome position: 18.18

GC content: 61.72

Gene sequence:

>465_bases
ATGAAATGCCCCTTTTGCGGCCACGCGGCCACCCAGGTGATTGATACCCGCATGTCGGAAGAAGGCGACACCGTGCGCCG
CCGCCGTCGCTGCGAATCCTGCGACCGCCGCTTCACGACCTACGAACGCATCGAGCTGTTCTTTCCGGCCGTCGTCAAGA
AGAACGGCAGCCGCGTCGACTACGACCGCAACAAGGTCAAGGATTCCATGCGCCTGGCGCTGCGCAAGCGCCCCGTTTCC
GCCGAAGCCATCGACGAGGCCATCGCCCGCATCGAAGAAAAACTCCTCAGCCACGGCGAAAAGGAAATCGGCAGCGACCG
CGTGGGCGAACTGGTGATGCGCGAACTCAAGCGGCTGGACAAGATCGGGTACATCCGCTTTGCGTCGGTGTACCGGAGTT
TTGAGGATCTGGCTGAGTTTCGGGACGTGCTGGACGAGGTTGCGGCGACGAATGTGCGGAAATAG

Upstream 100 bases:

>100_bases
AGTACCCTGCCGCGATGCGCCCCGAATTGAATGAGGGGCCATCGCGGCGTTGTTCTTTTAGCGCAGTGCGTTCTTTGAGG
TTGCCGAGGAGACCACCGGC

Downstream 100 bases:

>100_bases
CACGCACGCGAACGGCTTCTATCGCCGCTGCGCTCCGGCCGACGACTACCAGCAGCTCGATGCCGTAAGCGTGCCCCCAG
ATACCATTTTATTCCCCGCC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKCPFCGHAATQVIDTRMSEEGDTVRRRRRCESCDRRFTTYERIELFFPAVVKKNGSRVDYDRNKVKDSMRLALRKRPVS
AEAIDEAIARIEEKLLSHGEKEIGSDRVGELVMRELKRLDKIGYIRFASVYRSFEDLAEFRDVLDEVAATNVRK

Sequences:

>Translated_154_residues
MKCPFCGHAATQVIDTRMSEEGDTVRRRRRCESCDRRFTTYERIELFFPAVVKKNGSRVDYDRNKVKDSMRLALRKRPVS
AEAIDEAIARIEEKLLSHGEKEIGSDRVGELVMRELKRLDKIGYIRFASVYRSFEDLAEFRDVLDEVAATNVRK
>Mature_154_residues
MKCPFCGHAATQVIDTRMSEEGDTVRRRRRCESCDRRFTTYERIELFFPAVVKKNGSRVDYDRNKVKDSMRLALRKRPVS
AEAIDEAIARIEEKLLSHGEKEIGSDRVGELVMRELKRLDKIGYIRFASVYRSFEDLAEFRDVLDEVAATNVRK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=140, Percent_Identity=52.1428571428571, Blast_Score=150, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_RALPJ (B2U7G6)

Other databases:

- EMBL:   CP001068
- RefSeq:   YP_001898260.1
- GeneID:   6288855
- GenomeReviews:   CP001068_GR
- KEGG:   rpi:Rpic_0677
- HOGENOM:   HBG351755
- OMA:   RRRRECK
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17936; Mature: 17936

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCGHAATQVIDTRMSEEGDTVRRRRRCESCDRRFTTYERIELFFPAVVKKNGSRVD
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YDRNKVKDSMRLALRKRPVSAEAIDEAIARIEEKLLSHGEKEIGSDRVGELVMRELKRLD
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHH
KIGYIRFASVYRSFEDLAEFRDVLDEVAATNVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKCPFCGHAATQVIDTRMSEEGDTVRRRRRCESCDRRFTTYERIELFFPAVVKKNGSRVD
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
YDRNKVKDSMRLALRKRPVSAEAIDEAIARIEEKLLSHGEKEIGSDRVGELVMRELKRLD
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHH
KIGYIRFASVYRSFEDLAEFRDVLDEVAATNVRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA