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The map label for this gene is ltrA [H]

Identifier: 187927648

GI number: 187927648

Start: 588039

End: 588938

Strand: Direct

Name: ltrA [H]

Synonym: Rpic_0548

Alternate gene names: 187927648

Gene position: 588039-588938 (Clockwise)

Preceding gene: 187927644

Following gene: 187927654

Centisome position: 14.92

GC content: 64.0

Gene sequence:

>900_bases
ATGGATTTGCTCGCGCTTGCCGATTTCAACCTGGTTGCCCGACATGGAAGCTTTGGCGAGGCTGCCCGGGCGACGGGGCG
GCCGAAGGCGACGCTCTCTCGCAGGGTGTCGGAGCTGGAGGGCAGTCTCGAACTTCGATTGTTCGAGCGCGGATCACGCG
GGCTCAAGCTCACCCAGGAAGGGCATGCGCTGTACGAGCGCACGGGCACGCTGCTCACCGAGATTGCCGAGACCGCCGCT
GCAATTGCTTCGGGAAGCGAGCGGCCACGCGGACGTCTGCGCATCAGCGCCCCGATGCTTTTTTCCCAGACTGCCATGGG
CAAGCTGGTTGCCACGTTCGCACTGAAATATCCCGAGGTGCTGTTGGAGGTCACGACTGAAGACCGTGGCGTCGACATGA
TCGAGGAAGGGTACGACCTCGTGATCCGAGTCAACCCGGACCCCGACGAAAGCCTGATCGGACGCGTGTTTATGCGTGAT
CGCCTCGTGGTGGTGGCGAAACCGGGACTGGAGCGGCCAACAGGCAAGGCCCTTGCGCCGGCCGTCTTGCGCGGCGCTGG
TACGGGAAACGCCGCATGGGATATCACGGGTCCCGAGGGCAAGTCCCGCATCGCGATCAGGCCAGTCGCGCACTTGTCGT
CGCTGATCATGGTGCGCGACACTGTCCGTCTTGGCGTGGGTGCCGCCTGTTTGCCGGTGTCGCTCGTGGCCCACGATCTG
GAGGCCGGCACGTTGGTGCATTGGGGCGATGTGGACGGCCCCGATATCGCGCTATGGGCGCTTTACCCTTCCAGGCGGTT
GCTGAGCGCCCGCGTTTCCGCTTTTCTCGAGCACCTCAAAGATGCGTTCCCGACCGGCACGCCCCAAGAGCTGGCGGCCT
ATATGCATTCCTCACCATAG

Upstream 100 bases:

>100_bases
GTTCACTCCTTGAGTGGGTTGGGTTCCCAGCTAAGGTAGGTGATCCATCTGTGGTCCGGAAGATGCTATAAAGAGACGAG
GTATCTCACTGGCGGAACAC

Downstream 100 bases:

>100_bases
GAATATCCGGCGATAGAGCCTCGGAGTTTCCGCGCATTTCCGGCAATGGGCGATGCGCGATCTCTTCCGCCTCGGTGTGG
TTCAGTCCGAGCATGCGCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MDLLALADFNLVARHGSFGEAARATGRPKATLSRRVSELEGSLELRLFERGSRGLKLTQEGHALYERTGTLLTEIAETAA
AIASGSERPRGRLRISAPMLFSQTAMGKLVATFALKYPEVLLEVTTEDRGVDMIEEGYDLVIRVNPDPDESLIGRVFMRD
RLVVVAKPGLERPTGKALAPAVLRGAGTGNAAWDITGPEGKSRIAIRPVAHLSSLIMVRDTVRLGVGAACLPVSLVAHDL
EAGTLVHWGDVDGPDIALWALYPSRRLLSARVSAFLEHLKDAFPTGTPQELAAYMHSSP

Sequences:

>Translated_299_residues
MDLLALADFNLVARHGSFGEAARATGRPKATLSRRVSELEGSLELRLFERGSRGLKLTQEGHALYERTGTLLTEIAETAA
AIASGSERPRGRLRISAPMLFSQTAMGKLVATFALKYPEVLLEVTTEDRGVDMIEEGYDLVIRVNPDPDESLIGRVFMRD
RLVVVAKPGLERPTGKALAPAVLRGAGTGNAAWDITGPEGKSRIAIRPVAHLSSLIMVRDTVRLGVGAACLPVSLVAHDL
EAGTLVHWGDVDGPDIALWALYPSRRLLSARVSAFLEHLKDAFPTGTPQELAAYMHSSP
>Mature_299_residues
MDLLALADFNLVARHGSFGEAARATGRPKATLSRRVSELEGSLELRLFERGSRGLKLTQEGHALYERTGTLLTEIAETAA
AIASGSERPRGRLRISAPMLFSQTAMGKLVATFALKYPEVLLEVTTEDRGVDMIEEGYDLVIRVNPDPDESLIGRVFMRD
RLVVVAKPGLERPTGKALAPAVLRGAGTGNAAWDITGPEGKSRIAIRPVAHLSSLIMVRDTVRLGVGAACLPVSLVAHDL
EAGTLVHWGDVDGPDIALWALYPSRRLLSARVSAFLEHLKDAFPTGTPQELAAYMHSSP

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=28.1786941580756, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=30.6397306397306, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=28.0276816608997, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=26.2798634812287, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789440, Length=211, Percent_Identity=24.1706161137441, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789639, Length=287, Percent_Identity=26.1324041811847, Blast_Score=84, Evalue=8e-18,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=25.7731958762887, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788481, Length=303, Percent_Identity=24.4224422442244, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI157672245, Length=128, Percent_Identity=32.8125, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=167, Percent_Identity=26.3473053892216, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI87082132, Length=307, Percent_Identity=23.4527687296417, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32206; Mature: 32206

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLALADFNLVARHGSFGEAARATGRPKATLSRRVSELEGSLELRLFERGSRGLKLTQE
CCEEEEECCHHEECCCCCCHHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEECC
GHALYERTGTLLTEIAETAAAIASGSERPRGRLRISAPMLFSQTAMGKLVATFALKYPEV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCE
LLEVTTEDRGVDMIEEGYDLVIRVNPDPDESLIGRVFMRDRLVVVAKPGLERPTGKALAP
EEEECCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCHHHH
AVLRGAGTGNAAWDITGPEGKSRIAIRPVAHLSSLIMVRDTVRLGVGAACLPVSLVAHDL
HHHHCCCCCCCEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
EAGTLVHWGDVDGPDIALWALYPSRRLLSARVSAFLEHLKDAFPTGTPQELAAYMHSSP
CCCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MDLLALADFNLVARHGSFGEAARATGRPKATLSRRVSELEGSLELRLFERGSRGLKLTQE
CCEEEEECCHHEECCCCCCHHHHCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCEEECC
GHALYERTGTLLTEIAETAAAIASGSERPRGRLRISAPMLFSQTAMGKLVATFALKYPEV
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCE
LLEVTTEDRGVDMIEEGYDLVIRVNPDPDESLIGRVFMRDRLVVVAKPGLERPTGKALAP
EEEECCCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCHHHH
AVLRGAGTGNAAWDITGPEGKSRIAIRPVAHLSSLIMVRDTVRLGVGAACLPVSLVAHDL
HHHHCCCCCCCEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
EAGTLVHWGDVDGPDIALWALYPSRRLLSARVSAFLEHLKDAFPTGTPQELAAYMHSSP
CCCCEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]