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The map label for this gene is glcK [H]

Identifier: 187935739

GI number: 187935739

Start: 2150619

End: 2151509

Strand: Reverse

Name: glcK [H]

Synonym: CLL_A2056

Alternate gene names: 187935739

Gene position: 2151509-2150619 (Counterclockwise)

Preceding gene: 187934703

Following gene: 187932395

Centisome position: 56.61

GC content: 31.31

Gene sequence:

>891_bases
ATGAAATATTACATAGGTATAGATATAGGCGGAACAAACTTAAGAGCAGCAATATTAGATGAAAAATGTAACTTAGTAGA
TAAGCTTAAAATATCAAATGAAGTTGAAAAAGGGCCAGAATATAATTTAGACAAGCTAATATTAGAAATTAAAGAAAGGT
GGTCAGATAAAGAAATTATTTCAGTAGGTGTGGGGTGTCCAGGACCACTTGATATTAGAAGTGGAACAATATTAGTTACT
CCAAATTTAAGGACATGGGAATATTTTAAATTAAAAGAATACCTAGAAAATAAGTTTGATTTACCTGTGTTTGTAAATAA
TGATGCCAATGTAGCAGGATATAGTGAAGCAATGGTTGGAGCAGGAAAAGGTGCAGAAAGTGTTTACTATATGACACTAT
CAACAGGGATTGGTGGAGGCTTTATATATAAAGGTGAAATTGTTTCTGGCTTTAATAGCATAGCAGCTGAAATAGGTAAT
ATGATTATTAATGAAGATACATATAAACATTCTAATATGAACTATGGTGGACTTGAAGGTCAATGCAGTGGAGTAAATAT
AGCAAGGATATCAAGTGAAATTATAGGTGGAGAATTAACTACAAAAGATGTCTTTGAGGGTGCAGAAAAGGGCAATATGG
AATTGCAAAAAATGTTAAGTGAATGGGTTACAAATGTTTCAAAAGCAATAGCAAATATTATAGTTACAGTTGATCCAGAA
GTTATAGTTCTTGGTGGGTCAGTAATTATAAATAATCCATCTTACCTTAATAAGATTAAAGAAGAAACTCAGAAAAGAGT
CTTTGATGGTATTAAAATTAATATTAAGTTAGCTGAGATTGGTGATGACACTGGACTTATAGGTGCAGGGTTATTAGGTA
AGTTAAAATAA

Upstream 100 bases:

>100_bases
GTCCTTAAAGGTGACAGCATATTAATACCAGCTAAATTAGGTAAGTACGTTATAGAAGGAAACTTAACTTTATTAAAAAG
TTATATTTAGGAGGGCAAAC

Downstream 100 bases:

>100_bases
AATAATTGAATTGGAAGGCTACTCCATATGTATTTTACAAGGAGTAGTTTTATTAATTTCGAGAAAATATAATATTAATG
AAATATGAGGTTTGATAAAA

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKYYIGIDIGGTNLRAAILDEKCNLVDKLKISNEVEKGPEYNLDKLILEIKERWSDKEIISVGVGCPGPLDIRSGTILVT
PNLRTWEYFKLKEYLENKFDLPVFVNNDANVAGYSEAMVGAGKGAESVYYMTLSTGIGGGFIYKGEIVSGFNSIAAEIGN
MIINEDTYKHSNMNYGGLEGQCSGVNIARISSEIIGGELTTKDVFEGAEKGNMELQKMLSEWVTNVSKAIANIIVTVDPE
VIVLGGSVIINNPSYLNKIKEETQKRVFDGIKINIKLAEIGDDTGLIGAGLLGKLK

Sequences:

>Translated_296_residues
MKYYIGIDIGGTNLRAAILDEKCNLVDKLKISNEVEKGPEYNLDKLILEIKERWSDKEIISVGVGCPGPLDIRSGTILVT
PNLRTWEYFKLKEYLENKFDLPVFVNNDANVAGYSEAMVGAGKGAESVYYMTLSTGIGGGFIYKGEIVSGFNSIAAEIGN
MIINEDTYKHSNMNYGGLEGQCSGVNIARISSEIIGGELTTKDVFEGAEKGNMELQKMLSEWVTNVSKAIANIIVTVDPE
VIVLGGSVIINNPSYLNKIKEETQKRVFDGIKINIKLAEIGDDTGLIGAGLLGKLK
>Mature_296_residues
MKYYIGIDIGGTNLRAAILDEKCNLVDKLKISNEVEKGPEYNLDKLILEIKERWSDKEIISVGVGCPGPLDIRSGTILVT
PNLRTWEYFKLKEYLENKFDLPVFVNNDANVAGYSEAMVGAGKGAESVYYMTLSTGIGGGFIYKGEIVSGFNSIAAEIGN
MIINEDTYKHSNMNYGGLEGQCSGVNIARISSEIIGGELTTKDVFEGAEKGNMELQKMLSEWVTNVSKAIANIIVTVDPE
VIVLGGSVIINNPSYLNKIKEETQKRVFDGIKINIKLAEIGDDTGLIGAGLLGKLK

Specific function: Unknown

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=284, Percent_Identity=27.4647887323944, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4885285, Length=285, Percent_Identity=27.719298245614, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI298566325, Length=285, Percent_Identity=27.719298245614, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI190014632, Length=263, Percent_Identity=29.277566539924, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1787363, Length=303, Percent_Identity=25.0825082508251, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87081733, Length=306, Percent_Identity=25.8169934640523, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082230, Length=250, Percent_Identity=28, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790522, Length=299, Percent_Identity=24.7491638795987, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786891, Length=307, Percent_Identity=23.7785016286645, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787878, Length=220, Percent_Identity=23.6363636363636, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 32230; Mature: 32230

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYYIGIDIGGTNLRAAILDEKCNLVDKLKISNEVEKGPEYNLDKLILEIKERWSDKEII
CEEEEEEEECCCCEEEEEECCCCCHHHHHHHCCHHHCCCCCCHHHHHHHHHHHCCCCEEE
SVGVGCPGPLDIRSGTILVTPNLRTWEYFKLKEYLENKFDLPVFVNNDANVAGYSEAMVG
EEECCCCCCCEECCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHC
AGKGAESVYYMTLSTGIGGGFIYKGEIVSGFNSIAAEIGNMIINEDTYKHSNMNYGGLEG
CCCCCCEEEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCC
QCSGVNIARISSEIIGGELTTKDVFEGAEKGNMELQKMLSEWVTNVSKAIANIIVTVDPE
EECCEEHEEHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCC
VIVLGGSVIINNPSYLNKIKEETQKRVFDGIKINIKLAEIGDDTGLIGAGLLGKLK
EEEECCEEEECCCHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCEECCCCCCCCC
>Mature Secondary Structure
MKYYIGIDIGGTNLRAAILDEKCNLVDKLKISNEVEKGPEYNLDKLILEIKERWSDKEII
CEEEEEEEECCCCEEEEEECCCCCHHHHHHHCCHHHCCCCCCHHHHHHHHHHHCCCCEEE
SVGVGCPGPLDIRSGTILVTPNLRTWEYFKLKEYLENKFDLPVFVNNDANVAGYSEAMVG
EEECCCCCCCEECCCEEEECCCCCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHC
AGKGAESVYYMTLSTGIGGGFIYKGEIVSGFNSIAAEIGNMIINEDTYKHSNMNYGGLEG
CCCCCCEEEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCC
QCSGVNIARISSEIIGGELTTKDVFEGAEKGNMELQKMLSEWVTNVSKAIANIIVTVDPE
EECCEEHEEHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEECCC
VIVLGGSVIINNPSYLNKIKEETQKRVFDGIKINIKLAEIGDDTGLIGAGLLGKLK
EEEECCEEEECCCHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]