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The map label for this gene is adhB [H]

Identifier: 187935495

GI number: 187935495

Start: 3099614

End: 3100765

Strand: Reverse

Name: adhB [H]

Synonym: CLL_A3002

Alternate gene names: 187935495

Gene position: 3100765-3099614 (Counterclockwise)

Preceding gene: 187934724

Following gene: 187933217

Centisome position: 81.59

GC content: 32.47

Gene sequence:

>1152_bases
ATGAATTTTAAATTAGAACAAAAAGTTAAAGTTATTGTTCGTCACGAATTAGCGAATACTATTTTGCAAATTCTAAACAT
GGAAAAATATAAAAAACCTATGGTAGCCATTGACAGCTTTTTAGTAAATACGCCTATTATTCAAGGAATGTTTGCATTAT
TAAAAGAAAATAGCATGGATTATTTTGTCTACGATAAAATAGTTTCTAATCCACCTACTGATATTATTGATGATGGAGCT
AAATTATTCTTAAAAAATAATTGTGATAGTATTATAGGTATTGGAGGTGGAAGTGCTATTGATTCAGCAAGAGGAATCAA
TATTGTTAGAACTTTAGGTGGAAATATCAGAGATTATGCTTTTGAGAAAGATATTCCTGAATTTTGTAAAGGATTAATTT
CAGTGCCTACGACATCTGGTACCGGAAGTGAATTATCTAATGCTTTAATTGTTTCTGAACCAGAGACACATGAAAAGTTG
TCTGTTTTATCAAATAATGCTGTGAGTGAATATGCTGTTTTAGCTCCTGAGTTAGCAATTACACTTCCCAAAAGTATGAC
GGCAGCTACTGGTTTAGATGCATTTTCACATGCCGCTGAGGGATATACATCCAAATTATCTTCTCCAATTACAGATGCTA
TTTGTGAAAAAATTATGTATTTAATTGTGAAATATCTTCCTAAAGCTATAAAGAATGGAGCTGATATAGAAGCAAGAGAA
CGTATGATGGTTGCTGCTGCATTAGGTGGCTGGATGTTAAATAATGCAGGGACCCATGTTGGTCATTCACAGGCTCATAT
TATTGGTGCACTTTATGGAATTCCACATGGAATGGCATGTGCTTATGCTCTACCGGGTACTTTGTTATATACGGCTAAGG
TAAATCCAAAAAAAGTAAAAGAAATTGGATTAATTTTAGGGGCTGAATATCCGGCAAATCATACAGACTTAGAAATTGGT
GAAATCACAGCAGAAAAATTTAAATGGTTTAGAGATGAGGTAATTGGACTTGACTCTTTTAAAAAATTCAATGTTTCTAG
GGAAGAACTTATATCTAATGCAGAAAAGGTCGTTGAAGAACGTTTTGCAGGTAATTCACCAATGGAAATTAATTTAGATT
TAGCTGAAAATCTATTGAAATTTTATGAATAA

Upstream 100 bases:

>100_bases
TAGGTTTATAAAATGAAATGTATTAGTAAAAATATATTTATTGTAAAAGTTGATTTTAGGGGTAAAGGCAACAATGTTTA
TTAAAAACTAGGAGGATATT

Downstream 100 bases:

>100_bases
AGGAGGAATTAGACTATATCTATATTATGTGGAGAGACTATAGCATTTTTGTTAATAACTAATATTATATGAATATTCTT
TTAGTAAAAAACCTAATGTT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Alcohol dehydrogenase II; ADH II [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MNFKLEQKVKVIVRHELANTILQILNMEKYKKPMVAIDSFLVNTPIIQGMFALLKENSMDYFVYDKIVSNPPTDIIDDGA
KLFLKNNCDSIIGIGGGSAIDSARGINIVRTLGGNIRDYAFEKDIPEFCKGLISVPTTSGTGSELSNALIVSEPETHEKL
SVLSNNAVSEYAVLAPELAITLPKSMTAATGLDAFSHAAEGYTSKLSSPITDAICEKIMYLIVKYLPKAIKNGADIEARE
RMMVAAALGGWMLNNAGTHVGHSQAHIIGALYGIPHGMACAYALPGTLLYTAKVNPKKVKEIGLILGAEYPANHTDLEIG
EITAEKFKWFRDEVIGLDSFKKFNVSREELISNAEKVVEERFAGNSPMEINLDLAENLLKFYE

Sequences:

>Translated_383_residues
MNFKLEQKVKVIVRHELANTILQILNMEKYKKPMVAIDSFLVNTPIIQGMFALLKENSMDYFVYDKIVSNPPTDIIDDGA
KLFLKNNCDSIIGIGGGSAIDSARGINIVRTLGGNIRDYAFEKDIPEFCKGLISVPTTSGTGSELSNALIVSEPETHEKL
SVLSNNAVSEYAVLAPELAITLPKSMTAATGLDAFSHAAEGYTSKLSSPITDAICEKIMYLIVKYLPKAIKNGADIEARE
RMMVAAALGGWMLNNAGTHVGHSQAHIIGALYGIPHGMACAYALPGTLLYTAKVNPKKVKEIGLILGAEYPANHTDLEIG
EITAEKFKWFRDEVIGLDSFKKFNVSREELISNAEKVVEERFAGNSPMEINLDLAENLLKFYE
>Mature_383_residues
MNFKLEQKVKVIVRHELANTILQILNMEKYKKPMVAIDSFLVNTPIIQGMFALLKENSMDYFVYDKIVSNPPTDIIDDGA
KLFLKNNCDSIIGIGGGSAIDSARGINIVRTLGGNIRDYAFEKDIPEFCKGLISVPTTSGTGSELSNALIVSEPETHEKL
SVLSNNAVSEYAVLAPELAITLPKSMTAATGLDAFSHAAEGYTSKLSSPITDAICEKIMYLIVKYLPKAIKNGADIEARE
RMMVAAALGGWMLNNAGTHVGHSQAHIIGALYGIPHGMACAYALPGTLLYTAKVNPKKVKEIGLILGAEYPANHTDLEIG
EITAEKFKWFRDEVIGLDSFKKFNVSREELISNAEKVVEERFAGNSPMEINLDLAENLLKFYE

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=310, Percent_Identity=26.7741935483871, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI48994951, Length=355, Percent_Identity=30.4225352112676, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1789163, Length=361, Percent_Identity=24.6537396121884, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1787493, Length=360, Percent_Identity=28.6111111111111, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87082107, Length=285, Percent_Identity=30.8771929824561, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789386, Length=256, Percent_Identity=28.515625, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17537053, Length=344, Percent_Identity=24.7093023255814, Blast_Score=101, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6321181, Length=281, Percent_Identity=35.2313167259786, Blast_Score=158, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24657991, Length=394, Percent_Identity=24.8730964467005, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 41879; Mature: 41879

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKLEQKVKVIVRHELANTILQILNMEKYKKPMVAIDSFLVNTPIIQGMFALLKENSMD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YFVYDKIVSNPPTDIIDDGAKLFLKNNCDSIIGIGGGSAIDSARGINIVRTLGGNIRDYA
EEEEHHHHCCCCCHHHCCCHHEEEECCCCCEEECCCCCHHHCCCCCHHHHHCCCCHHHHH
FEKDIPEFCKGLISVPTTSGTGSELSNALIVSEPETHEKLSVLSNNAVSEYAVLAPELAI
HHCCHHHHHHHHHCCCCCCCCCHHHCCCEEECCCCHHHHHHHHHCCCHHHHHHHCCHHHE
TLPKSMTAATGLDAFSHAAEGYTSKLSSPITDAICEKIMYLIVKYLPKAIKNGADIEARE
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RMMVAAALGGWMLNNAGTHVGHSQAHIIGALYGIPHGMACAYALPGTLLYTAKVNPKKVK
HHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCEEEEEECCCHHHHH
EIGLILGAEYPANHTDLEIGEITAEKFKWFRDEVIGLDSFKKFNVSREELISNAEKVVEE
HHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHH
RFAGNSPMEINLDLAENLLKFYE
HHCCCCCCEEEHHHHHHHHHHCC
>Mature Secondary Structure
MNFKLEQKVKVIVRHELANTILQILNMEKYKKPMVAIDSFLVNTPIIQGMFALLKENSMD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YFVYDKIVSNPPTDIIDDGAKLFLKNNCDSIIGIGGGSAIDSARGINIVRTLGGNIRDYA
EEEEHHHHCCCCCHHHCCCHHEEEECCCCCEEECCCCCHHHCCCCCHHHHHCCCCHHHHH
FEKDIPEFCKGLISVPTTSGTGSELSNALIVSEPETHEKLSVLSNNAVSEYAVLAPELAI
HHCCHHHHHHHHHCCCCCCCCCHHHCCCEEECCCCHHHHHHHHHCCCHHHHHHHCCHHHE
TLPKSMTAATGLDAFSHAAEGYTSKLSSPITDAICEKIMYLIVKYLPKAIKNGADIEARE
ECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
RMMVAAALGGWMLNNAGTHVGHSQAHIIGALYGIPHGMACAYALPGTLLYTAKVNPKKVK
HHHHHHHHCCHHCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCEEEEEECCCHHHHH
EIGLILGAEYPANHTDLEIGEITAEKFKWFRDEVIGLDSFKKFNVSREELISNAEKVVEE
HHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHH
RFAGNSPMEINLDLAENLLKFYE
HHCCCCCCEEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3584063; 2308827; 2935393 [H]