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The map label for this gene is atpA [H]

Identifier: 187935460

GI number: 187935460

Start: 2937451

End: 2939229

Strand: Reverse

Name: atpA [H]

Synonym: CLL_A2861

Alternate gene names: 187935460

Gene position: 2939229-2937451 (Counterclockwise)

Preceding gene: 187932947

Following gene: 187933540

Centisome position: 77.34

GC content: 35.98

Gene sequence:

>1779_bases
GTGAAGACCGGAAAGATAATTAAGGTTTCAGGACCTTTAGTAGTTGCTGAAGGTATGGATGAAGCTAATATATATGACGT
TTGTAAGGTTGGAGAAAAGGGTCTTATCGGAGAAATCATCGAAATGAGAGGCGATAAGGCATCAATCCAAGTATATGAAG
AAACTTCAGGAATAGGACCTGGGGATCCAGTTGTTACAACTGGAGAACCTTTAAGTGTTGAACTTGGGCCAGGACTTATT
GAATCAATGTTTGATGGAATACAAAGACCACTAGATGCATTTATGGAGGCTGCTAAGTCTAGTTTTTTAACTAGGGGAGT
ATCAGTTCCTTCATTAAATAGAGAAAAGAAGTGGGACTTTAAACCAACAGCAAAAGTTGGAGATGATGTTAAATCTGGAA
CTGTAATAGGTACAGTACAAGAAACACCAGTTGTTGAACAAAGAATAATGATTCCAATTGGAATTGAAGGTAAAATAAAA
GAAATTAAAGCTGGTAGCTTCACAGTTACTGAAACAATTGCTATAGTTGAAACTGAAAAAGGAGATAGAGAAGTTCAATT
AATGCAAAAATGGCCAGTAAGAAAAGGAAGACCATATTCAGCAAAGATTAACCCAGTTGAGCCAATGCTTACAGGACAAA
GAGTTATAGATACGTTTTTCCCTGTTGCTAAAGGTGGAGCTGCTGCTATTCCAGGACCATTTGGAGCTGGAAAAACAGTA
ACACAACATCAAATCGCTAAATGGGGAGATGCAGAAATCGTTGTTTACGTTGGATGTGGAGAACGTGGTAATGAAATGAC
AGACGTTGTTAATGAGTTCCCAGAACTTATTGACCCTAAGACTGGTGAAAGTTTAATGAAGAGAACAGTTCTTATAGCTA
ATACTTCAAACATGCCAGTTGCGGCTAGAGAAGCTTCAATATATACAGGTATTACAATAGCTGAATACTTCAGAGACATG
GGATACTCAGTATCAATAATGGCTGATTCAACTTCAAGATGGGCTGAGGCATTAAGAGAAATGTCTGGTAGACTTGAAGA
AATGCCTGGTGATGAAGGATATCCAGCTTACCTTGGATCAAGACTTGCTGACTACTATGAAAGAGCTGGTAAAGTTGAAT
GTTTAGGTAATGATGGAAGAATTGGGTCTATAACAGCAATCGGTGCAGTATCGCCTCCAGGAGGAGATATTTCAGAACCA
GTATCACAATCAACACTTAGAATAGTTAAGGTGTTCTGGGGTCTAGATGCACAACTTGCATATCAAAGACATTTCCCAAC
TATTAACTGGTTAACATCATATTCATTATATGCTGATACAATAGATAAATGGATGAATGGTAATGTTGCTGAAAATTGGG
GAGCATTAAGATTAGAAGCTATGACTATACTTCAAGATGAAGCTCAATTACAAGAAATCGTAAGACTTGTTGGTATTGAT
GCATTATCTGAAAAAGATAGATTGAAATTAGATGTTGCTAAATCAATCAGAGAAGACTATTTACAACAAAATGGTTTCCA
TGAAATTGATACTTATACATCATTAAAGAAGCAATATAAGATGTTAAATCTTATATTAGGATATAGAAAAGAAGCAGAAA
GAGCTTTAGAAGCTGGAGTATACTTAAATGATATCTTAGCTATGGAAGACTTAAAAGATAGAATTGCTAGAAGTAAGTAC
ATACACGAAGATGATTTAGAAAAAATGGATCAAATCGTTGTAGACTTAAAGAATGCAATTGATAACCTAATAAACAAAGG
AGGGGTAGCAAATGCTTAA

Upstream 100 bases:

>100_bases
CAAGCAATCAAGGAACATTAAATATAGGTATGCAAAGAATAAGCGATAACGTAGAAAAAGCTGTAGGCGTTAATATTTTA
TAGAAAGGTAGGTTGGTAAG

Downstream 100 bases:

>100_bases
AGAGTATAGAACAGTTACTGAAGTTGTTGGCCCTTTGATGGTTGTTGAAGGTGTTGAAGGCGTTAAGTATGATGAACTAG
TTGAAATTGAACTTCATACT

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 592; Mature: 592

Protein sequence:

>592_residues
MKTGKIIKVSGPLVVAEGMDEANIYDVCKVGEKGLIGEIIEMRGDKASIQVYEETSGIGPGDPVVTTGEPLSVELGPGLI
ESMFDGIQRPLDAFMEAAKSSFLTRGVSVPSLNREKKWDFKPTAKVGDDVKSGTVIGTVQETPVVEQRIMIPIGIEGKIK
EIKAGSFTVTETIAIVETEKGDREVQLMQKWPVRKGRPYSAKINPVEPMLTGQRVIDTFFPVAKGGAAAIPGPFGAGKTV
TQHQIAKWGDAEIVVYVGCGERGNEMTDVVNEFPELIDPKTGESLMKRTVLIANTSNMPVAAREASIYTGITIAEYFRDM
GYSVSIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLADYYERAGKVECLGNDGRIGSITAIGAVSPPGGDISEP
VSQSTLRIVKVFWGLDAQLAYQRHFPTINWLTSYSLYADTIDKWMNGNVAENWGALRLEAMTILQDEAQLQEIVRLVGID
ALSEKDRLKLDVAKSIREDYLQQNGFHEIDTYTSLKKQYKMLNLILGYRKEAERALEAGVYLNDILAMEDLKDRIARSKY
IHEDDLEKMDQIVVDLKNAIDNLINKGGVANA

Sequences:

>Translated_592_residues
MKTGKIIKVSGPLVVAEGMDEANIYDVCKVGEKGLIGEIIEMRGDKASIQVYEETSGIGPGDPVVTTGEPLSVELGPGLI
ESMFDGIQRPLDAFMEAAKSSFLTRGVSVPSLNREKKWDFKPTAKVGDDVKSGTVIGTVQETPVVEQRIMIPIGIEGKIK
EIKAGSFTVTETIAIVETEKGDREVQLMQKWPVRKGRPYSAKINPVEPMLTGQRVIDTFFPVAKGGAAAIPGPFGAGKTV
TQHQIAKWGDAEIVVYVGCGERGNEMTDVVNEFPELIDPKTGESLMKRTVLIANTSNMPVAAREASIYTGITIAEYFRDM
GYSVSIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLADYYERAGKVECLGNDGRIGSITAIGAVSPPGGDISEP
VSQSTLRIVKVFWGLDAQLAYQRHFPTINWLTSYSLYADTIDKWMNGNVAENWGALRLEAMTILQDEAQLQEIVRLVGID
ALSEKDRLKLDVAKSIREDYLQQNGFHEIDTYTSLKKQYKMLNLILGYRKEAERALEAGVYLNDILAMEDLKDRIARSKY
IHEDDLEKMDQIVVDLKNAIDNLINKGGVANA
>Mature_592_residues
MKTGKIIKVSGPLVVAEGMDEANIYDVCKVGEKGLIGEIIEMRGDKASIQVYEETSGIGPGDPVVTTGEPLSVELGPGLI
ESMFDGIQRPLDAFMEAAKSSFLTRGVSVPSLNREKKWDFKPTAKVGDDVKSGTVIGTVQETPVVEQRIMIPIGIEGKIK
EIKAGSFTVTETIAIVETEKGDREVQLMQKWPVRKGRPYSAKINPVEPMLTGQRVIDTFFPVAKGGAAAIPGPFGAGKTV
TQHQIAKWGDAEIVVYVGCGERGNEMTDVVNEFPELIDPKTGESLMKRTVLIANTSNMPVAAREASIYTGITIAEYFRDM
GYSVSIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGSRLADYYERAGKVECLGNDGRIGSITAIGAVSPPGGDISEP
VSQSTLRIVKVFWGLDAQLAYQRHFPTINWLTSYSLYADTIDKWMNGNVAENWGALRLEAMTILQDEAQLQEIVRLVGID
ALSEKDRLKLDVAKSIREDYLQQNGFHEIDTYTSLKKQYKMLNLILGYRKEAERALEAGVYLNDILAMEDLKDRIARSKY
IHEDDLEKMDQIVVDLKNAIDNLINKGGVANA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=540, Percent_Identity=52.037037037037, Blast_Score=580, Evalue=1e-165,
Organism=Homo sapiens, GI32189394, Length=339, Percent_Identity=29.4985250737463, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19913426, Length=349, Percent_Identity=28.3667621776504, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI19913428, Length=350, Percent_Identity=26.5714285714286, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI50345984, Length=272, Percent_Identity=28.6764705882353, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4757810, Length=272, Percent_Identity=28.6764705882353, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1790170, Length=346, Percent_Identity=29.1907514450867, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1788251, Length=317, Percent_Identity=29.3375394321767, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1790172, Length=236, Percent_Identity=28.3898305084746, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17565854, Length=557, Percent_Identity=50.4488330341113, Blast_Score=573, Evalue=1e-163,
Organism=Caenorhabditis elegans, GI25144756, Length=350, Percent_Identity=29.4285714285714, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=346, Percent_Identity=27.7456647398844, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17510931, Length=340, Percent_Identity=27.6470588235294, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI71988080, Length=267, Percent_Identity=28.8389513108614, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71988063, Length=267, Percent_Identity=28.8389513108614, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71988074, Length=267, Percent_Identity=28.8389513108614, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320016, Length=321, Percent_Identity=51.0903426791277, Blast_Score=329, Evalue=6e-91,
Organism=Saccharomyces cerevisiae, GI6319603, Length=356, Percent_Identity=29.4943820224719, Blast_Score=111, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6322581, Length=334, Percent_Identity=29.3413173652695, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6319370, Length=236, Percent_Identity=28.8135593220339, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24583988, Length=542, Percent_Identity=51.8450184501845, Blast_Score=578, Evalue=1e-165,
Organism=Drosophila melanogaster, GI24583986, Length=542, Percent_Identity=51.8450184501845, Blast_Score=578, Evalue=1e-165,
Organism=Drosophila melanogaster, GI24583984, Length=542, Percent_Identity=51.8450184501845, Blast_Score=578, Evalue=1e-165,
Organism=Drosophila melanogaster, GI24583992, Length=598, Percent_Identity=47.8260869565217, Blast_Score=569, Evalue=1e-162,
Organism=Drosophila melanogaster, GI20129479, Length=561, Percent_Identity=50.445632798574, Blast_Score=563, Evalue=1e-160,
Organism=Drosophila melanogaster, GI28574560, Length=304, Percent_Identity=32.8947368421053, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24638766, Length=312, Percent_Identity=31.4102564102564, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281361666, Length=366, Percent_Identity=26.775956284153, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24646341, Length=366, Percent_Identity=26.775956284153, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136796, Length=366, Percent_Identity=26.775956284153, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24658560, Length=272, Percent_Identity=27.9411764705882, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 65065; Mature: 65065

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGKIIKVSGPLVVAEGMDEANIYDVCKVGEKGLIGEIIEMRGDKASIQVYEETSGIGP
CCCCCEEEECCCEEEECCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCCCC
GDPVVTTGEPLSVELGPGLIESMFDGIQRPLDAFMEAAKSSFLTRGVSVPSLNREKKWDF
CCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
KPTAKVGDDVKSGTVIGTVQETPVVEQRIMIPIGIEGKIKEIKAGSFTVTETIAIVETEK
CCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCHHEECCCCEEEEEEEEEEEECC
GDREVQLMQKWPVRKGRPYSAKINPVEPMLTGQRVIDTFFPVAKGGAAAIPGPFGAGKTV
CCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
TQHQIAKWGDAEIVVYVGCGERGNEMTDVVNEFPELIDPKTGESLMKRTVLIANTSNMPV
HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCEEEEEECCCCCE
AAREASIYTGITIAEYFRDMGYSVSIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGS
EECCCHHEECHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RLADYYERAGKVECLGNDGRIGSITAIGAVSPPGGDISEPVSQSTLRIVKVFWGLDAQLA
HHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
YQRHFPTINWLTSYSLYADTIDKWMNGNVAENWGALRLEAMTILQDEAQLQEIVRLVGID
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCH
ALSEKDRLKLDVAKSIREDYLQQNGFHEIDTYTSLKKQYKMLNLILGYRKEAERALEAGV
HCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YLNDILAMEDLKDRIARSKYIHEDDLEKMDQIVVDLKNAIDNLINKGGVANA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTGKIIKVSGPLVVAEGMDEANIYDVCKVGEKGLIGEIIEMRGDKASIQVYEETSGIGP
CCCCCEEEECCCEEEECCCCCCCHHHHHHCCCCCHHHHHHHHCCCCCEEEEEECCCCCCC
GDPVVTTGEPLSVELGPGLIESMFDGIQRPLDAFMEAAKSSFLTRGVSVPSLNREKKWDF
CCCEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
KPTAKVGDDVKSGTVIGTVQETPVVEQRIMIPIGIEGKIKEIKAGSFTVTETIAIVETEK
CCCCCCCCCCCCCEEEEECCCCCCCCCEEEEEECCCCCHHEECCCCEEEEEEEEEEEECC
GDREVQLMQKWPVRKGRPYSAKINPVEPMLTGQRVIDTFFPVAKGGAAAIPGPFGAGKTV
CCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
TQHQIAKWGDAEIVVYVGCGERGNEMTDVVNEFPELIDPKTGESLMKRTVLIANTSNMPV
HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCEEEEEECCCCCE
AAREASIYTGITIAEYFRDMGYSVSIMADSTSRWAEALREMSGRLEEMPGDEGYPAYLGS
EECCCHHEECHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
RLADYYERAGKVECLGNDGRIGSITAIGAVSPPGGDISEPVSQSTLRIVKVFWGLDAQLA
HHHHHHHHCCCEEEECCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
YQRHFPTINWLTSYSLYADTIDKWMNGNVAENWGALRLEAMTILQDEAQLQEIVRLVGID
HHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCH
ALSEKDRLKLDVAKSIREDYLQQNGFHEIDTYTSLKKQYKMLNLILGYRKEAERALEAGV
HCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
YLNDILAMEDLKDRIARSKYIHEDDLEKMDQIVVDLKNAIDNLINKGGVANA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA