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The map label for this gene is hemA [H]

Identifier: 187935430

GI number: 187935430

Start: 2989617

End: 2990822

Strand: Reverse

Name: hemA [H]

Synonym: CLL_A2909

Alternate gene names: 187935430

Gene position: 2990822-2989617 (Counterclockwise)

Preceding gene: 187933514

Following gene: 187935213

Centisome position: 78.7

GC content: 25.79

Gene sequence:

>1206_bases
ATGATAGCAGTGTTAGGAATAAAAAGAAATACACCAATAGAAATTAGGGAAAAATTAACTATAAAAGTAAACAAACATGA
TGAGTATCTAGATAAATTGTTAAAATATTTAGAGGGGGTTGTCATTCTTGCAACTTGTAATAGAACAGAAATTTATTTTA
ATGTTTCTTCTATAAATGAAGAACTATTAAAAAAGATTTTTGAAATTTTTAACTGGAATTATAGTTATAGAAAATATATT
TTTATATCTGAAGACAAAAAGGCTTGCAAACATTTATTTGAAGTAACTTGCGGTTTTCATTCAAAGATTTTAGGTGAAGA
TCAGATTTTGGGGCAAGTAAAGACGTCTTATTTTAAATCTTTAAATGCAAAAGCCCTTAATTTAGAATTACAAAGATTAT
TTCAATATGCTATAACATGTGGTAAAAAATTTAAAAGTCAATCAAGGTTATTTGAAATTCCGGTATCATCAGCCTCAATA
GTTGTAAATGAATCTATTAATAAAGACTGTAAAAAATTTATGGTATTAGGATATGGAGATGTAGGACGTCTAACTATGAA
GTATTTACTGGCACATAATATAAATGAAGTGTATTTGGCAGTTAGAAATAAGAAAATAAAAGACGAAATTATGGATAAGA
GAGTTAATGTAATAGACTTTGAAGAAAAAAATAAATACATAAATGATATGGATTGTGTGATTTCATGTACATCAGCACCT
CATATAGTCATAAAAAAGCAAGACATAAATAACATTGGAAGTAATATAATAATTTATGATTTAGCAGTACCTAGAGATGT
GGATGATGATATTAATGATATAGATAGAGCTCAGGTTTATAATATAGATAATATAAGTCACATAAATGATGGTAATAAAA
AGATGCGTTTTGATAAGATGGATTCTAATAAATTTATTTTAGAAAAATACTTAAATGAGTATTATGAATGGAAAAGACTG
AGAAGTATTGCTCCATTCATAGAAGAATTAAAAGTAACGTCTAAAGAAATATATAATAAAAGAATAACCACTTTTAAAAA
TAAATGTACAGATAAAGATGATGTTGATTTAGCGAATAGAATGATAAAGAGCACATCTGACTATTATATGAATAGAGCTA
TAGATATAATGAAAGAAGAAACTTTAAAGGGAAGTGAAGAGGAATGTTTAAGGATAATAAAGAGCATATTTATGACGAAG
AAATAG

Upstream 100 bases:

>100_bases
ATTAGAAATTAACTTTTTTTATTGTATGTTTTAATATAAAATAAGTATATTAAATTAGAACATATAAATATTTTAAATAA
TTATACAAGGTGGAAAAATA

Downstream 100 bases:

>100_bases
ATTATTCTTTTATTTCACTACTTTCTAATAAAATAAATATTGGTGTTATTGGTGGCGGCAGAGCTGGGTTTATAAAGATT
AAACATTTTTTAAAAACAGG

Product: glutamyl-tRNA reductase

Products: NA

Alternate protein names: GluTR [H]

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MIAVLGIKRNTPIEIREKLTIKVNKHDEYLDKLLKYLEGVVILATCNRTEIYFNVSSINEELLKKIFEIFNWNYSYRKYI
FISEDKKACKHLFEVTCGFHSKILGEDQILGQVKTSYFKSLNAKALNLELQRLFQYAITCGKKFKSQSRLFEIPVSSASI
VVNESINKDCKKFMVLGYGDVGRLTMKYLLAHNINEVYLAVRNKKIKDEIMDKRVNVIDFEEKNKYINDMDCVISCTSAP
HIVIKKQDINNIGSNIIIYDLAVPRDVDDDINDIDRAQVYNIDNISHINDGNKKMRFDKMDSNKFILEKYLNEYYEWKRL
RSIAPFIEELKVTSKEIYNKRITTFKNKCTDKDDVDLANRMIKSTSDYYMNRAIDIMKEETLKGSEEECLRIIKSIFMTK
K

Sequences:

>Translated_401_residues
MIAVLGIKRNTPIEIREKLTIKVNKHDEYLDKLLKYLEGVVILATCNRTEIYFNVSSINEELLKKIFEIFNWNYSYRKYI
FISEDKKACKHLFEVTCGFHSKILGEDQILGQVKTSYFKSLNAKALNLELQRLFQYAITCGKKFKSQSRLFEIPVSSASI
VVNESINKDCKKFMVLGYGDVGRLTMKYLLAHNINEVYLAVRNKKIKDEIMDKRVNVIDFEEKNKYINDMDCVISCTSAP
HIVIKKQDINNIGSNIIIYDLAVPRDVDDDINDIDRAQVYNIDNISHINDGNKKMRFDKMDSNKFILEKYLNEYYEWKRL
RSIAPFIEELKVTSKEIYNKRITTFKNKCTDKDDVDLANRMIKSTSDYYMNRAIDIMKEETLKGSEEECLRIIKSIFMTK
K
>Mature_401_residues
MIAVLGIKRNTPIEIREKLTIKVNKHDEYLDKLLKYLEGVVILATCNRTEIYFNVSSINEELLKKIFEIFNWNYSYRKYI
FISEDKKACKHLFEVTCGFHSKILGEDQILGQVKTSYFKSLNAKALNLELQRLFQYAITCGKKFKSQSRLFEIPVSSASI
VVNESINKDCKKFMVLGYGDVGRLTMKYLLAHNINEVYLAVRNKKIKDEIMDKRVNVIDFEEKNKYINDMDCVISCTSAP
HIVIKKQDINNIGSNIIIYDLAVPRDVDDDINDIDRAQVYNIDNISHINDGNKKMRFDKMDSNKFILEKYLNEYYEWKRL
RSIAPFIEELKVTSKEIYNKRITTFKNKCTDKDDVDLANRMIKSTSDYYMNRAIDIMKEETLKGSEEECLRIIKSIFMTK
K

Specific function: Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) [H]

COG id: COG0373

COG function: function code H; Glutamyl-tRNA reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamyl-tRNA reductase family [H]

Homologues:

Organism=Escherichia coli, GI1787461, Length=359, Percent_Identity=27.0194986072423, Blast_Score=146, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000343
- InterPro:   IPR015895
- InterPro:   IPR016040
- InterPro:   IPR018214
- InterPro:   IPR006151 [H]

Pfam domain/function: PF05201 GlutR_N; PF01488 Shikimate_DH [H]

EC number: =1.2.1.70 [H]

Molecular weight: Translated: 47009; Mature: 47009

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: PS00747 GLUTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAVLGIKRNTPIEIREKLTIKVNKHDEYLDKLLKYLEGVVILATCNRTEIYFNVSSINE
CEEEEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHHCCEEEEEECCCEEEEEEHHHHHH
ELLKKIFEIFNWNYSYRKYIFISEDKKACKHLFEVTCGFHSKILGEDQILGQVKTSYFKS
HHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHH
LNAKALNLELQRLFQYAITCGKKFKSQSRLFEIPVSSASIVVNESINKDCKKFMVLGYGD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCHHHHHEEEECCCC
VGRLTMKYLLAHNINEVYLAVRNKKIKDEIMDKRVNVIDFEEKNKYINDMDCVISCTSAP
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEEHHHCCCCCCCEEEEEECCCC
HIVIKKQDINNIGSNIIIYDLAVPRDVDDDINDIDRAQVYNIDNISHINDGNKKMRFDKM
EEEEEECCCCCCCCCEEEEEEECCCCCCCCCHHCCHHEEECCCCCCCCCCCCCEEEEECC
DSNKFILEKYLNEYYEWKRLRSIAPFIEELKVTSKEIYNKRITTFKNKCTDKDDVDLANR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MIKSTSDYYMNRAIDIMKEETLKGSEEECLRIIKSIFMTKK
HHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIAVLGIKRNTPIEIREKLTIKVNKHDEYLDKLLKYLEGVVILATCNRTEIYFNVSSINE
CEEEEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHHCCEEEEEECCCEEEEEEHHHHHH
ELLKKIFEIFNWNYSYRKYIFISEDKKACKHLFEVTCGFHSKILGEDQILGQVKTSYFKS
HHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHH
LNAKALNLELQRLFQYAITCGKKFKSQSRLFEIPVSSASIVVNESINKDCKKFMVLGYGD
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCCCHHHHHEEEECCCC
VGRLTMKYLLAHNINEVYLAVRNKKIKDEIMDKRVNVIDFEEKNKYINDMDCVISCTSAP
HHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCCEEEEHHHCCCCCCCEEEEEECCCC
HIVIKKQDINNIGSNIIIYDLAVPRDVDDDINDIDRAQVYNIDNISHINDGNKKMRFDKM
EEEEEECCCCCCCCCEEEEEEECCCCCCCCCHHCCHHEEECCCCCCCCCCCCCEEEEECC
DSNKFILEKYLNEYYEWKRLRSIAPFIEELKVTSKEIYNKRITTFKNKCTDKDDVDLANR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
MIKSTSDYYMNRAIDIMKEETLKGSEEECLRIIKSIFMTKK
HHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA