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The map label for this gene is aroC [H]

Identifier: 187935282

GI number: 187935282

Start: 3250492

End: 3251565

Strand: Reverse

Name: aroC [H]

Synonym: CLL_A3141

Alternate gene names: 187935282

Gene position: 3251565-3250492 (Counterclockwise)

Preceding gene: 187935747

Following gene: 187934308

Centisome position: 85.56

GC content: 30.63

Gene sequence:

>1074_bases
ATGAGTGGAATTTGGGGGAATAAATTAAAAATTTCTATATTTGGTGAATCACATGGAAATGCAATAGGCATAACTATAGA
TGGACTTCCAGCTGGATTTAAAATTAATATGGAAGAAGTCTTAAAAGAAATGTCTAGAAGAGCACCAGGAAAAAGTAATC
TTTCTACATCAAGAAAAGAAGGAGATAAACCTGAAATACTTAGTGGCTTTTTTGAAGGAAAAACTACGGGTACTCCACTT
TGTGCAATGATTAAAAATAGTGATATGCATTCGAAGGATTATAGTGAATTAAAGAATTTAATGAGACCTGGTCATGCAGA
TTATAGTGGAAAAATTAAATACAGTGGATTTAATGATTATAGAGGTGGAGGACACTTTTCAGGAAGAATAACAGCACCAT
TAGTTTTTGCAGGATCTATATGTAAACAAATATTAGAAAAAGAAAATATATATGTAGGGGCTCATATTAAAAGAATAGGA
AATATTGAGGATAAGGATTTTAGTAAAATAAATTTAACTAAAGAACTTATAAACAGTTTGAGTAGTGAAGAGTTACCAGT
TTTAATAAAAGAGAATGAAGAAATAATGAGAAACGAAATAATTGAAGCTAAAAAAGATGGTGATTCAATAGGTGGAATTA
TAGAATGTGGAATTATTGGAGTGAAAGCAGGAGTTGGAAATCCATTTTTTGATTCTATAGAATCTACATTAGCTCATTTA
TTATTTTCTGTACCAGCAGTAAAAGGTGTTGAATTTGGAGAAGGATTTGAAATGAGTAAACTTAGAGGTTCACAGTGCAA
TGATGAATATTATTATGATGGAGATGAAGTAAAGACATATAGCAACAATAATGGAGGCATATTAGGTGGAATATCTAATG
GAATGCCAATATTATTTAAAGCAGTTATAAAACCAACTCCATCAATATCCAAAGAACAACGAAGTATAAATATAAGCGAA
AAGAAAAATGGTGTTATTACAGTTAAAGGTAGACATGACCCATGTATAGTGCAAAGAGCTGTGCCAGTAATTGAAAGTGT
TGCAGCTATTGGATTACTTGATTTAATGCTTTAA

Upstream 100 bases:

>100_bases
ACAGTTTGCATGGAACCAATTATTTTAGAAGATTATGAATGTATTTCAAAATCTTATCCAGCATTTTTTGATGACTTTAA
AGCATTAGGAGGAAACTTTC

Downstream 100 bases:

>100_bases
ATATAAAGAGTTGAAAATTGATAGTGGAAAATAAAGAGTTGAGGATGGAAAGTTGAGAGTTTTGTAATAAATTCTAATAC
AGAATTTAAAAATATATTTT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSGIWGNKLKISIFGESHGNAIGITIDGLPAGFKINMEEVLKEMSRRAPGKSNLSTSRKEGDKPEILSGFFEGKTTGTPL
CAMIKNSDMHSKDYSELKNLMRPGHADYSGKIKYSGFNDYRGGGHFSGRITAPLVFAGSICKQILEKENIYVGAHIKRIG
NIEDKDFSKINLTKELINSLSSEELPVLIKENEEIMRNEIIEAKKDGDSIGGIIECGIIGVKAGVGNPFFDSIESTLAHL
LFSVPAVKGVEFGEGFEMSKLRGSQCNDEYYYDGDEVKTYSNNNGGILGGISNGMPILFKAVIKPTPSISKEQRSINISE
KKNGVITVKGRHDPCIVQRAVPVIESVAAIGLLDLML

Sequences:

>Translated_357_residues
MSGIWGNKLKISIFGESHGNAIGITIDGLPAGFKINMEEVLKEMSRRAPGKSNLSTSRKEGDKPEILSGFFEGKTTGTPL
CAMIKNSDMHSKDYSELKNLMRPGHADYSGKIKYSGFNDYRGGGHFSGRITAPLVFAGSICKQILEKENIYVGAHIKRIG
NIEDKDFSKINLTKELINSLSSEELPVLIKENEEIMRNEIIEAKKDGDSIGGIIECGIIGVKAGVGNPFFDSIESTLAHL
LFSVPAVKGVEFGEGFEMSKLRGSQCNDEYYYDGDEVKTYSNNNGGILGGISNGMPILFKAVIKPTPSISKEQRSINISE
KKNGVITVKGRHDPCIVQRAVPVIESVAAIGLLDLML
>Mature_356_residues
SGIWGNKLKISIFGESHGNAIGITIDGLPAGFKINMEEVLKEMSRRAPGKSNLSTSRKEGDKPEILSGFFEGKTTGTPLC
AMIKNSDMHSKDYSELKNLMRPGHADYSGKIKYSGFNDYRGGGHFSGRITAPLVFAGSICKQILEKENIYVGAHIKRIGN
IEDKDFSKINLTKELINSLSSEELPVLIKENEEIMRNEIIEAKKDGDSIGGIIECGIIGVKAGVGNPFFDSIESTLAHLL
FSVPAVKGVEFGEGFEMSKLRGSQCNDEYYYDGDEVKTYSNNNGGILGGISNGMPILFKAVIKPTPSISKEQRSINISEK
KNGVITVKGRHDPCIVQRAVPVIESVAAIGLLDLML

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=357, Percent_Identity=43.6974789915966, Blast_Score=247, Evalue=9e-67,
Organism=Saccharomyces cerevisiae, GI6321290, Length=364, Percent_Identity=36.5384615384615, Blast_Score=248, Evalue=9e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 38824; Mature: 38693

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGIWGNKLKISIFGESHGNAIGITIDGLPAGFKINMEEVLKEMSRRAPGKSNLSTSRKE
CCCCCCCEEEEEEEECCCCCEEEEEECCCCCCEEECHHHHHHHHHHCCCCCCCCCCCCCC
GDKPEILSGFFEGKTTGTPLCAMIKNSDMHSKDYSELKNLMRPGHADYSGKIKYSGFNDY
CCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCC
RGGGHFSGRITAPLVFAGSICKQILEKENIYVGAHIKRIGNIEDKDFSKINLTKELINSL
CCCCCCCCEECHHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHC
SSEELPVLIKENEEIMRNEIIEAKKDGDSIGGIIECGIIGVKAGVGNPFFDSIESTLAHL
CCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHH
LFSVPAVKGVEFGEGFEMSKLRGSQCNDEYYYDGDEVKTYSNNNGGILGGISNGMPILFK
HHHCCCCCCCCCCCCCCHHHCCCCCCCCCCEECCCCEEEEECCCCCEEEECCCCHHHHHH
AVIKPTPSISKEQRSINISEKKNGVITVKGRHDPCIVQRAVPVIESVAAIGLLDLML
HHHCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGIWGNKLKISIFGESHGNAIGITIDGLPAGFKINMEEVLKEMSRRAPGKSNLSTSRKE
CCCCCCEEEEEEEECCCCCEEEEEECCCCCCEEECHHHHHHHHHHCCCCCCCCCCCCCC
GDKPEILSGFFEGKTTGTPLCAMIKNSDMHSKDYSELKNLMRPGHADYSGKIKYSGFNDY
CCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCC
RGGGHFSGRITAPLVFAGSICKQILEKENIYVGAHIKRIGNIEDKDFSKINLTKELINSL
CCCCCCCCEECHHHHHHHHHHHHHHHHCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHC
SSEELPVLIKENEEIMRNEIIEAKKDGDSIGGIIECGIIGVKAGVGNPFFDSIESTLAHL
CCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHHHHHH
LFSVPAVKGVEFGEGFEMSKLRGSQCNDEYYYDGDEVKTYSNNNGGILGGISNGMPILFK
HHHCCCCCCCCCCCCCCHHHCCCCCCCCCCEECCCCEEEEECCCCCEEEECCCCHHHHHH
AVIKPTPSISKEQRSINISEKKNGVITVKGRHDPCIVQRAVPVIESVAAIGLLDLML
HHHCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]