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The map label for this gene is aroA [H]

Identifier: 187935747

GI number: 187935747

Start: 3251543

End: 3252844

Strand: Reverse

Name: aroA [H]

Synonym: CLL_A3142

Alternate gene names: 187935747

Gene position: 3252844-3251543 (Counterclockwise)

Preceding gene: 187933372

Following gene: 187935282

Centisome position: 85.59

GC content: 29.19

Gene sequence:

>1302_bases
ATGGGAACTTTTAAAATTTATCCTGGAAAACTAAAAGGAGAAGTTAAAACTCCACCATCTAAAAGCATGGCACATAGAGG
TGTTATTTGTGCAGCTTTAGGAGATGGAATAAGTAAAATAAGAAATATTAATTATTCAGATGATATTATAGCAACTATTA
ATGCAATGCGGTCATTAGGAGCTATAATAACAAAGGAAGATGAGTATCTCCATGTTATTGGAATAAAATCTGAAAAGTGT
AAAAAAAATATAGAATTAAATAGAACAATAGATTGTAATGAATCAGGTTCAACATTAAGATTTTTAGTTCCAATTTCGTG
TATTTTTGAAGGTAGTAGTAGGTTTATAGGGAGAGGAAATTTAGGGAAAAGACCTTTAGATACATATTATGAAATTTTTG
ATAATCAAGGAATTAAGCATTCATATAAAAAAGGAAAGCTTGATTTAAGAATTGAGGGCATACTAAAATGTGGAGAGTTT
AAGCTACGTGGAGATATAAGTTCTCAATTTATTAGTGGTATGTTATTTACACTTCCTCTTTTAGAGGGAGACTCAAAAGT
AATAATAACAACAGACTTAGAATCTAAAGGATATATTGATTTAACATTAAGTGCTATGAGTGATTTTGGAATTGAAATTA
TAAATAATAATTATAGGGAGTTTATAATTAAAGGAAATCAAACTTATAAAAGTAGAAATTATAGAATAGAAGGTGATTAT
TCTCAAGCAGCATTTTTTCTAGTTGCTGATGCATTGAAGAGTGAAGTGTTTATAAATGATTTAAATTTAGAATCTCTTCA
AGGTGATAAGGAAGTTATAGAAATACTTGAAAGAATGAATATGAAAATAAAAAATATTGATAATGGCCTTTTGGGAATTC
AAAGAGAAAACTTAGGGTCAACTATTATTGATGGTTCTCAATGTCCAGATATAATTCCTGTTATCTCTTTAGCTGCTAGT
TTGTGCAATGGTAGAACTGAAATAATAAATGTAGGAAGATTACGGATTAAAGAATGTGATAGGTTAAGTGCAGTTGCAAG
TGAGCTAAATAAATTGGGAGCTCATATAATTGAAAAAGAAGACAGCTTAATAATTGATGGAGTTAAAACTTTAAAAGGTG
GAGTAAAGGTTTGGAGTCATAAAGATCATAGAATTGCTATGATGCTTGCAATAGCTTCTACAGTTTGCATGGAACCAATT
ATTTTAGAAGATTATGAATGTATTTCAAAATCTTATCCAGCATTTTTTGATGACTTTAAAGCATTAGGAGGAAACTTTCA
TGAGTGGAATTTGGGGGAATAA

Upstream 100 bases:

>100_bases
TCAAGTAAATCTTATATTTTGTAACTGTACACTAACAAAAAGCAAATAAGTTTTAATTAATGTATTATCTTAATATTAAA
CAACTAAAAGGGGGACACAA

Downstream 100 bases:

>100_bases
ATTAAAAATTTCTATATTTGGTGAATCACATGGAAATGCAATAGGCATAACTATAGATGGACTTCCAGCTGGATTTAAAA
TTAATATGGAAGAAGTCTTA

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MGTFKIYPGKLKGEVKTPPSKSMAHRGVICAALGDGISKIRNINYSDDIIATINAMRSLGAIITKEDEYLHVIGIKSEKC
KKNIELNRTIDCNESGSTLRFLVPISCIFEGSSRFIGRGNLGKRPLDTYYEIFDNQGIKHSYKKGKLDLRIEGILKCGEF
KLRGDISSQFISGMLFTLPLLEGDSKVIITTDLESKGYIDLTLSAMSDFGIEIINNNYREFIIKGNQTYKSRNYRIEGDY
SQAAFFLVADALKSEVFINDLNLESLQGDKEVIEILERMNMKIKNIDNGLLGIQRENLGSTIIDGSQCPDIIPVISLAAS
LCNGRTEIINVGRLRIKECDRLSAVASELNKLGAHIIEKEDSLIIDGVKTLKGGVKVWSHKDHRIAMMLAIASTVCMEPI
ILEDYECISKSYPAFFDDFKALGGNFHEWNLGE

Sequences:

>Translated_433_residues
MGTFKIYPGKLKGEVKTPPSKSMAHRGVICAALGDGISKIRNINYSDDIIATINAMRSLGAIITKEDEYLHVIGIKSEKC
KKNIELNRTIDCNESGSTLRFLVPISCIFEGSSRFIGRGNLGKRPLDTYYEIFDNQGIKHSYKKGKLDLRIEGILKCGEF
KLRGDISSQFISGMLFTLPLLEGDSKVIITTDLESKGYIDLTLSAMSDFGIEIINNNYREFIIKGNQTYKSRNYRIEGDY
SQAAFFLVADALKSEVFINDLNLESLQGDKEVIEILERMNMKIKNIDNGLLGIQRENLGSTIIDGSQCPDIIPVISLAAS
LCNGRTEIINVGRLRIKECDRLSAVASELNKLGAHIIEKEDSLIIDGVKTLKGGVKVWSHKDHRIAMMLAIASTVCMEPI
ILEDYECISKSYPAFFDDFKALGGNFHEWNLGE
>Mature_432_residues
GTFKIYPGKLKGEVKTPPSKSMAHRGVICAALGDGISKIRNINYSDDIIATINAMRSLGAIITKEDEYLHVIGIKSEKCK
KNIELNRTIDCNESGSTLRFLVPISCIFEGSSRFIGRGNLGKRPLDTYYEIFDNQGIKHSYKKGKLDLRIEGILKCGEFK
LRGDISSQFISGMLFTLPLLEGDSKVIITTDLESKGYIDLTLSAMSDFGIEIINNNYREFIIKGNQTYKSRNYRIEGDYS
QAAFFLVADALKSEVFINDLNLESLQGDKEVIEILERMNMKIKNIDNGLLGIQRENLGSTIIDGSQCPDIIPVISLAASL
CNGRTEIINVGRLRIKECDRLSAVASELNKLGAHIIEKEDSLIIDGVKTLKGGVKVWSHKDHRIAMMLAIASTVCMEPII
LEDYECISKSYPAFFDDFKALGGNFHEWNLGE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=426, Percent_Identity=30.5164319248826, Blast_Score=193, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6320332, Length=463, Percent_Identity=26.5658747300216, Blast_Score=141, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 48233; Mature: 48102

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTFKIYPGKLKGEVKTPPSKSMAHRGVICAALGDGISKIRNINYSDDIIATINAMRSLG
CCCEEECCCCCCCCCCCCCCHHHHHCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
AIITKEDEYLHVIGIKSEKCKKNIELNRTIDCNESGSTLRFLVPISCIFEGSSRFIGRGN
CEEECCCCEEEEEECCCHHHHCCCCCCCEECCCCCCCEEEEEEEEEEEECCCCCEEECCC
LGKRPLDTYYEIFDNQGIKHSYKKGKLDLRIEGILKCGEFKLRGDISSQFISGMLFTLPL
CCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCEEEECCHHHHHHHHHHHEEEE
LEGDSKVIITTDLESKGYIDLTLSAMSDFGIEIINNNYREFIIKGNQTYKSRNYRIEGDY
ECCCCEEEEEEECCCCCEEEEEEECHHHCCEEEECCCCEEEEEECCCEEECCCEEEECCH
SQAAFFLVADALKSEVFINDLNLESLQGDKEVIEILERMNMKIKNIDNGLLGIQRENLGS
HHHHHHHHHHHHHCCEEEEECCHHHCCCCHHHHHHHHHCCCEEEECCCCEEEEEECCCCC
TIIDGSQCPDIIPVISLAASLCNGRTEIINVGRLRIKECDRLSAVASELNKLGAHIIEKE
EEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHCCCC
DSLIIDGVKTLKGGVKVWSHKDHRIAMMLAIASTVCMEPIILEDYECISKSYPAFFDDFK
CCEEECCHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCEECCHHHHHCCCCHHHHHHH
ALGGNFHEWNLGE
HHCCCCCCCCCCC
>Mature Secondary Structure 
GTFKIYPGKLKGEVKTPPSKSMAHRGVICAALGDGISKIRNINYSDDIIATINAMRSLG
CCEEECCCCCCCCCCCCCCHHHHHCCEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
AIITKEDEYLHVIGIKSEKCKKNIELNRTIDCNESGSTLRFLVPISCIFEGSSRFIGRGN
CEEECCCCEEEEEECCCHHHHCCCCCCCEECCCCCCCEEEEEEEEEEEECCCCCEEECCC
LGKRPLDTYYEIFDNQGIKHSYKKGKLDLRIEGILKCGEFKLRGDISSQFISGMLFTLPL
CCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCEEEECCHHHHHHHHHHHEEEE
LEGDSKVIITTDLESKGYIDLTLSAMSDFGIEIINNNYREFIIKGNQTYKSRNYRIEGDY
ECCCCEEEEEEECCCCCEEEEEEECHHHCCEEEECCCCEEEEEECCCEEECCCEEEECCH
SQAAFFLVADALKSEVFINDLNLESLQGDKEVIEILERMNMKIKNIDNGLLGIQRENLGS
HHHHHHHHHHHHHCCEEEEECCHHHCCCCHHHHHHHHHCCCEEEECCCCEEEEEECCCCC
TIIDGSQCPDIIPVISLAASLCNGRTEIINVGRLRIKECDRLSAVASELNKLGAHIIEKE
EEECCCCCCHHHHHHHHHHHHHCCCEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHCCCC
DSLIIDGVKTLKGGVKVWSHKDHRIAMMLAIASTVCMEPIILEDYECISKSYPAFFDDFK
CCEEECCHHHHCCCEEEECCCCCHHHHHHHHHHHHHCCCCEECCHHHHHCCCCHHHHHHH
ALGGNFHEWNLGE
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA