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The map label for this gene is phoR [H]

Identifier: 187934995

GI number: 187934995

Start: 3300307

End: 3301692

Strand: Reverse

Name: phoR [H]

Synonym: CLL_A3179

Alternate gene names: 187934995

Gene position: 3301692-3300307 (Counterclockwise)

Preceding gene: 187935582

Following gene: 187934015

Centisome position: 86.88

GC content: 22.66

Gene sequence:

>1386_bases
ATGATGAAAACACTAAAGGGAAAAATAATGATAGGAATTATTTTCGCCCTCATTATATTCAATTTTGGGTTAAGCATTTT
TATATATAAGACTTTTTACACAAATATAAAGAATAATATTAAAGATGATATGGAGAGTATTAGAAAGTTTAGTACAAGCA
CCTTAAAATATAGTGCTATGGTTATTGAAGATGATCTTAAAGTAAAAAATAAAACTGTTTATGAAGTTAACAATAATTAT
GATTGTTATGTGGGATTATATGATTCTGATAATAAAGTAATAGACTATAAAGGAAATACATTATTTGAAAATAGTATTAA
TAATATATTAAAAAGTTCAAAAGGAAAAAGTTCAATAATAATATTTAATATTAAAAATGGACTGATTTGTACATATGTAT
ATCCTATTTATCTTAATGGAAAATACGATTCAAGCCTAATTATACAAAAAAGTTATAATGATTACTATAATAGCATTAAA
ACTACAATGACTAATATAATAGCAGCACAAATTGTTCTTTTAATAGTAATAATAACTGCACTAAATTATTTCATAAATAA
AATAATAAGTCCTTTAAAAAAGCTCAGCATACAGATAAAAAAATATGGAGAAGGTAAAGATGTCGATAAGATTTTAGTGA
AATCTGAAGATGAAATAGGACAAGTTACTAATTCTTTTAATGAAATGATTGAGGAAAAGAAAAAATTAGAAAATATATCA
AAAGATTTTTTCAATAATTCAACTCATGAACTTAAAACTCCAGTTACTTCAATATATGGATATCTTCAAATATTAAAAGA
AGAAGAGTTGGATGATATGGATGAGGAATTTAAAAAAAGGGCTATTAATAGAATGATGATGGAATGTGAAAAATTAAAAG
AACTTATACAGAAGCTTCTTGAAATATCAAGATGTGGTGTTAGAAAAAAAGAGATAAAGAAAGAGATAAGCCTTAATATA
TTAATAAGTGAAATATGTGATAGATTAATTGACCGAAGTAAAAGATTAAATAAGGAGTTTATTATAGATATAGAGGACAT
TAGTGTATCAGCTATAAAAGAAGATTTAGAACATATAATTTTAAATTTAATTGATAATTCTCTAAAATACTCTAAAGGTA
AAGAGATATTTATTTCTCTTAATAAAACTACTAAAAATAATTTTGTATTTAAGATAACGAATAAGATTTCTTCAATACCA
AAAAATATTTCTGAAAATTTATTAGAGCCTTTTATTAAATATAATGAATTTGATGGCAATCTAGAAGAGAGCATTTCAAG
TTCTGGCTTGGGATTATATTTATGTAATGAATTAGCTCAAAAAAATATGTTTACTTTAAAATATGATATAAAAAATGATG
AAATTTCTTTCTATTTATTAGGTTGA

Upstream 100 bases:

>100_bases
GGGCAAATCTTGGAGAAGATAAAGAAAATTCAGTAATAGAAACAGTTTTTGGTGTGGGATATGTAATAAGATAAACTCTT
AAATTTAGGAAGTGAAAAAT

Downstream 100 bases:

>100_bases
AAATTATATTAAAGTGTTACATGGATGTTACAAAAGTGTTAAATAAGTAGTACATGTTAAATAGATACTACAAGAATATT
ACAAAAATGTAAAAAGCATT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MMKTLKGKIMIGIIFALIIFNFGLSIFIYKTFYTNIKNNIKDDMESIRKFSTSTLKYSAMVIEDDLKVKNKTVYEVNNNY
DCYVGLYDSDNKVIDYKGNTLFENSINNILKSSKGKSSIIIFNIKNGLICTYVYPIYLNGKYDSSLIIQKSYNDYYNSIK
TTMTNIIAAQIVLLIVIITALNYFINKIISPLKKLSIQIKKYGEGKDVDKILVKSEDEIGQVTNSFNEMIEEKKKLENIS
KDFFNNSTHELKTPVTSIYGYLQILKEEELDDMDEEFKKRAINRMMMECEKLKELIQKLLEISRCGVRKKEIKKEISLNI
LISEICDRLIDRSKRLNKEFIIDIEDISVSAIKEDLEHIILNLIDNSLKYSKGKEIFISLNKTTKNNFVFKITNKISSIP
KNISENLLEPFIKYNEFDGNLEESISSSGLGLYLCNELAQKNMFTLKYDIKNDEISFYLLG

Sequences:

>Translated_461_residues
MMKTLKGKIMIGIIFALIIFNFGLSIFIYKTFYTNIKNNIKDDMESIRKFSTSTLKYSAMVIEDDLKVKNKTVYEVNNNY
DCYVGLYDSDNKVIDYKGNTLFENSINNILKSSKGKSSIIIFNIKNGLICTYVYPIYLNGKYDSSLIIQKSYNDYYNSIK
TTMTNIIAAQIVLLIVIITALNYFINKIISPLKKLSIQIKKYGEGKDVDKILVKSEDEIGQVTNSFNEMIEEKKKLENIS
KDFFNNSTHELKTPVTSIYGYLQILKEEELDDMDEEFKKRAINRMMMECEKLKELIQKLLEISRCGVRKKEIKKEISLNI
LISEICDRLIDRSKRLNKEFIIDIEDISVSAIKEDLEHIILNLIDNSLKYSKGKEIFISLNKTTKNNFVFKITNKISSIP
KNISENLLEPFIKYNEFDGNLEESISSSGLGLYLCNELAQKNMFTLKYDIKNDEISFYLLG
>Mature_461_residues
MMKTLKGKIMIGIIFALIIFNFGLSIFIYKTFYTNIKNNIKDDMESIRKFSTSTLKYSAMVIEDDLKVKNKTVYEVNNNY
DCYVGLYDSDNKVIDYKGNTLFENSINNILKSSKGKSSIIIFNIKNGLICTYVYPIYLNGKYDSSLIIQKSYNDYYNSIK
TTMTNIIAAQIVLLIVIITALNYFINKIISPLKKLSIQIKKYGEGKDVDKILVKSEDEIGQVTNSFNEMIEEKKKLENIS
KDFFNNSTHELKTPVTSIYGYLQILKEEELDDMDEEFKKRAINRMMMECEKLKELIQKLLEISRCGVRKKEIKKEISLNI
LISEICDRLIDRSKRLNKEFIIDIEDISVSAIKEDLEHIILNLIDNSLKYSKGKEIFISLNKTTKNNFVFKITNKISSIP
KNISENLLEPFIKYNEFDGNLEESISSSGLGLYLCNELAQKNMFTLKYDIKNDEISFYLLG

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=257, Percent_Identity=24.124513618677, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1786600, Length=214, Percent_Identity=23.8317757009346, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=201, Percent_Identity=24.3781094527363, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53379; Mature: 53379

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKTLKGKIMIGIIFALIIFNFGLSIFIYKTFYTNIKNNIKDDMESIRKFSTSTLKYSAM
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
VIEDDLKVKNKTVYEVNNNYDCYVGLYDSDNKVIDYKGNTLFENSINNILKSSKGKSSII
EEECCCCCCCCEEEEECCCEEEEEEEECCCCEEEEECCCEEHHHHHHHHHHCCCCCCEEE
IFNIKNGLICTYVYPIYLNGKYDSSLIIQKSYNDYYNSIKTTMTNIIAAQIVLLIVIITA
EEEECCCEEEEEEEEEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNYFINKIISPLKKLSIQIKKYGEGKDVDKILVKSEDEIGQVTNSFNEMIEEKKKLENIS
HHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
KDFFNNSTHELKTPVTSIYGYLQILKEEELDDMDEEFKKRAINRMMMECEKLKELIQKLL
HHHHCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EISRCGVRKKEIKKEISLNILISEICDRLIDRSKRLNKEFIIDIEDISVSAIKEDLEHII
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
LNLIDNSLKYSKGKEIFISLNKTTKNNFVFKITNKISSIPKNISENLLEPFIKYNEFDGN
HHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LEESISSSGLGLYLCNELAQKNMFTLKYDIKNDEISFYLLG
HHHHHCCCCCHHHHHHHHHHCCEEEEEEEECCCCEEEEEEC
>Mature Secondary Structure
MMKTLKGKIMIGIIFALIIFNFGLSIFIYKTFYTNIKNNIKDDMESIRKFSTSTLKYSAM
CCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
VIEDDLKVKNKTVYEVNNNYDCYVGLYDSDNKVIDYKGNTLFENSINNILKSSKGKSSII
EEECCCCCCCCEEEEECCCEEEEEEEECCCCEEEEECCCEEHHHHHHHHHHCCCCCCEEE
IFNIKNGLICTYVYPIYLNGKYDSSLIIQKSYNDYYNSIKTTMTNIIAAQIVLLIVIITA
EEEECCCEEEEEEEEEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNYFINKIISPLKKLSIQIKKYGEGKDVDKILVKSEDEIGQVTNSFNEMIEEKKKLENIS
HHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
KDFFNNSTHELKTPVTSIYGYLQILKEEELDDMDEEFKKRAINRMMMECEKLKELIQKLL
HHHHCCCCHHHHCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EISRCGVRKKEIKKEISLNILISEICDRLIDRSKRLNKEFIIDIEDISVSAIKEDLEHII
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
LNLIDNSLKYSKGKEIFISLNKTTKNNFVFKITNKISSIPKNISENLLEPFIKYNEFDGN
HHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCC
LEESISSSGLGLYLCNELAQKNMFTLKYDIKNDEISFYLLG
HHHHHCCCCCHHHHHHHHHHCCEEEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2556368 [H]