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The map label for this gene is yycF [H]

Identifier: 187935582

GI number: 187935582

Start: 3301719

End: 3302447

Strand: Reverse

Name: yycF [H]

Synonym: CLL_A3180

Alternate gene names: 187935582

Gene position: 3302447-3301719 (Counterclockwise)

Preceding gene: 187934407

Following gene: 187934995

Centisome position: 86.9

GC content: 27.43

Gene sequence:

>729_bases
ATGTTAAAAAAAAGAATACTAGTAGTAGAAGATGAATTTTCAATTAATGATACATTAAAATTTGCACTTTCAAAGGAAAA
TTTTGAAGTAAAAGGAGCATATAATGGTGAAAGTGCTTTAAAACTTCTTGAAGAATTTCAGCCACATTTAGTTTTACTAG
ATATAATGCTTCCTGATATAAGCGGGTTTGAATTATGTAAGTCTATAAGTCAGAAATTCTATGTAATTATGCTTACAGCA
AGGGATGATGTGATTGATAAAATATTAGGGATGGAAATAGGCGCAGATGATTATATAACAAAGCCATTTGAAATTAGGGA
AGTTATAGCAAGAATCAATGCTATTTTTAGAACTGCAGGTAAAAATATTTGGAATAATGAAAATAACAACATGATAATGA
ATGTTTTAGAATGCAATACAAATGATGATAATAAGGGGAATACTGTAGAAGATGAAATTTCTATTAATTTCAATACAAGA
ACAGTAATAAAAGATGGAGAAGAAATCATATTAAAGAGAAAAGAATTTGAATTATTAAGTTACCTATATAAGAATAAGGG
AATTGTTTTTACAAGACAACAACTTTTAAATGAGGTTTGGGGATATGATTATTATGGTGATACTAGAACTGTTGATGTTC
ATATTAGAAGATTAAGGGCAAATCTTGGAGAAGATAAAGAAAATTCAGTAATAGAAACAGTTTTTGGTGTGGGATATGTA
ATAAGATAA

Upstream 100 bases:

>100_bases
TTTTTATTATGATATAATTGGTATAAAATGAATTAATATTTTAAAATGTAATATAATGGACAAAGATAAACGTTAAACAA
TTATTATTTGGAGGCGTAAC

Downstream 100 bases:

>100_bases
ACTCTTAAATTTAGGAAGTGAAAAATATGATGAAAACACTAAAGGGAAAAATAATGATAGGAATTATTTTCGCCCTCATT
ATATTCAATTTTGGGTTAAG

Product: alkaline phosphatase synthesis transcriptional regulatory proteinphoP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MLKKRILVVEDEFSINDTLKFALSKENFEVKGAYNGESALKLLEEFQPHLVLLDIMLPDISGFELCKSISQKFYVIMLTA
RDDVIDKILGMEIGADDYITKPFEIREVIARINAIFRTAGKNIWNNENNNMIMNVLECNTNDDNKGNTVEDEISINFNTR
TVIKDGEEIILKRKEFELLSYLYKNKGIVFTRQQLLNEVWGYDYYGDTRTVDVHIRRLRANLGEDKENSVIETVFGVGYV
IR

Sequences:

>Translated_242_residues
MLKKRILVVEDEFSINDTLKFALSKENFEVKGAYNGESALKLLEEFQPHLVLLDIMLPDISGFELCKSISQKFYVIMLTA
RDDVIDKILGMEIGADDYITKPFEIREVIARINAIFRTAGKNIWNNENNNMIMNVLECNTNDDNKGNTVEDEISINFNTR
TVIKDGEEIILKRKEFELLSYLYKNKGIVFTRQQLLNEVWGYDYYGDTRTVDVHIRRLRANLGEDKENSVIETVFGVGYV
IR
>Mature_242_residues
MLKKRILVVEDEFSINDTLKFALSKENFEVKGAYNGESALKLLEEFQPHLVLLDIMLPDISGFELCKSISQKFYVIMLTA
RDDVIDKILGMEIGADDYITKPFEIREVIARINAIFRTAGKNIWNNENNNMIMNVLECNTNDDNKGNTVEDEISINFNTR
TVIKDGEEIILKRKEFELLSYLYKNKGIVFTRQQLLNEVWGYDYYGDTRTVDVHIRRLRANLGEDKENSVIETVFGVGYV
IR

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=243, Percent_Identity=37.037037037037, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1790860, Length=249, Percent_Identity=37.7510040160643, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789809, Length=240, Percent_Identity=32.9166666666667, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1788394, Length=240, Percent_Identity=35.4166666666667, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790863, Length=244, Percent_Identity=35.2459016393443, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1786784, Length=240, Percent_Identity=30.8333333333333, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790552, Length=240, Percent_Identity=33.75, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=237, Percent_Identity=31.2236286919831, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI2367329, Length=241, Percent_Identity=36.9294605809129, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1789402, Length=240, Percent_Identity=32.5, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787229, Length=245, Percent_Identity=31.8367346938775, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786911, Length=239, Percent_Identity=30.1255230125523, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787375, Length=239, Percent_Identity=28.4518828451883, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693140, Length=243, Percent_Identity=30.4526748971193, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=35.5140186915888, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790299, Length=113, Percent_Identity=33.6283185840708, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 28008; Mature: 28008

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKKRILVVEDEFSINDTLKFALSKENFEVKGAYNGESALKLLEEFQPHLVLLDIMLPDI
CCCCEEEEEECCCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCC
SGFELCKSISQKFYVIMLTARDDVIDKILGMEIGADDYITKPFEIREVIARINAIFRTAG
CHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
KNIWNNENNNMIMNVLECNTNDDNKGNTVEDEISINFNTRTVIKDGEEIILKRKEFELLS
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHH
YLYKNKGIVFTRQQLLNEVWGYDYYGDTRTVDVHIRRLRANLGEDKENSVIETVFGVGYV
HHHHCCCEEEEHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHCCEE
IR
CC
>Mature Secondary Structure
MLKKRILVVEDEFSINDTLKFALSKENFEVKGAYNGESALKLLEEFQPHLVLLDIMLPDI
CCCCEEEEEECCCCCCCCEEEEEECCCEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCC
SGFELCKSISQKFYVIMLTARDDVIDKILGMEIGADDYITKPFEIREVIARINAIFRTAG
CHHHHHHHHCCCEEEEEEECCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
KNIWNNENNNMIMNVLECNTNDDNKGNTVEDEISINFNTRTVIKDGEEIILKRKEFELLS
CCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHH
YLYKNKGIVFTRQQLLNEVWGYDYYGDTRTVDVHIRRLRANLGEDKENSVIETVFGVGYV
HHHHCCCEEEEHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHCCEE
IR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]