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The map label for this gene is trxA [H]

Identifier: 187934945

GI number: 187934945

Start: 3730155

End: 3730466

Strand: Reverse

Name: trxA [H]

Synonym: CLL_A3522

Alternate gene names: 187934945

Gene position: 3730466-3730155 (Counterclockwise)

Preceding gene: 187935573

Following gene: 187932597

Centisome position: 98.16

GC content: 24.04

Gene sequence:

>312_bases
ATGATAAAACAAGTTTATAGTTTTGATTTTAAAAAAGAAATAGAAGATGGGACCACAGTAGTCAACTTTTATTCAAATTT
AGGAAGTCCTTCTAAGTTAGTTGCACCTGTATTTAATGAAGTGAAAGATGAAGTAGCTGATAAAGCAAAATTTTTAGAAG
TAAATTTAGATCAAAATAGAGATTTAATAAAAAAATATGATATTCCTTCAATTCAATCTATTATGATATTTAAAAAAGGT
ATAGAAGTAAGTAAATTAAATGGATTTTTACCTAAAGAGGCATTAAAACAAAATGTAGAAGCTAACTTATAA

Upstream 100 bases:

>100_bases
ATTACCAATAATTAAAATAAAAATAAAATTTATGTATATAGAAATAAAATAAGCTAAAAATAATTCTAACAAATAAATAT
AAAAATTGGAGGTTAGAATT

Downstream 100 bases:

>100_bases
AAAAACTGCTTCTTATTATATTTTTGTATAAATAAGAAGCTTATATTTTTTTATACTAAATTATAGAATTTTTGAAGGCT
AAATAAATTTAATTTTAAAT

Product: thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 103; Mature: 103

Protein sequence:

>103_residues
MIKQVYSFDFKKEIEDGTTVVNFYSNLGSPSKLVAPVFNEVKDEVADKAKFLEVNLDQNRDLIKKYDIPSIQSIMIFKKG
IEVSKLNGFLPKEALKQNVEANL

Sequences:

>Translated_103_residues
MIKQVYSFDFKKEIEDGTTVVNFYSNLGSPSKLVAPVFNEVKDEVADKAKFLEVNLDQNRDLIKKYDIPSIQSIMIFKKG
IEVSKLNGFLPKEALKQNVEANL
>Mature_103_residues
MIKQVYSFDFKKEIEDGTTVVNFYSNLGSPSKLVAPVFNEVKDEVADKAKFLEVNLDQNRDLIKKYDIPSIQSIMIFKKG
IEVSKLNGFLPKEALKQNVEANL

Specific function: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=97, Percent_Identity=35.0515463917526, Blast_Score=66, Evalue=3e-13,
Organism=Escherichia coli, GI1788936, Length=78, Percent_Identity=38.4615384615385, Blast_Score=64, Evalue=2e-12,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11714; Mature: 11714

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQVYSFDFKKEIEDGTTVVNFYSNLGSPSKLVAPVFNEVKDEVADKAKFLEVNLDQNR
CCCCHHCCCHHHHHCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
DLIKKYDIPSIQSIMIFKKGIEVSKLNGFLPKEALKQNVEANL
HHHHHCCCCCHHHHHHHHCCCCHHHHCCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MIKQVYSFDFKKEIEDGTTVVNFYSNLGSPSKLVAPVFNEVKDEVADKAKFLEVNLDQNR
CCCCHHCCCHHHHHCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCC
DLIKKYDIPSIQSIMIFKKGIEVSKLNGFLPKEALKQNVEANL
HHHHHCCCCCHHHHHHHHCCCCHHHHCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA