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The map label for this gene is tagA [H]

Identifier: 187934932

GI number: 187934932

Start: 2544165

End: 2544878

Strand: Reverse

Name: tagA [H]

Synonym: CLL_A2459

Alternate gene names: 187934932

Gene position: 2544878-2544165 (Counterclockwise)

Preceding gene: 187935614

Following gene: 187935658

Centisome position: 66.96

GC content: 26.19

Gene sequence:

>714_bases
ATGTTTACAGATATACTTAATTTTAAAATATTTAATGGCAGCAAAAAAGAACTTATGAAATACATAGAGAAATTTGAAAA
GATAAATATTATATCAGGAAATCCAGAGATATTATTTAATGGATTAAATAATAAAATACTTAATAGATGTTTTAAAGAAG
ACAACTCAGTAATTATTCCTGATGGGGTAGGGACAGTGCTTGCTTCTAAATTGTTAAAAAATCCAGTAAAAGAAAAAATA
GCTGGAATAGAGGTTATGAAAGAGCTTTTATCAAAAGCTAATTTAGAAAATAAATCTATTTATTTATTAGGAGCAAAAGA
AGAAGTAATTCAAAAATGTGGAGAAAATATTAAAAATGAATTTAATAATTTAGATATATGCGGTTTACATAATGGATATT
TTGATTTAGATAGTTGTGCTGAAATAATAGATGAAATAAAAGAGAAAAAGCCTTGGGTAATTTTTATTGCTATGGGGTGT
CCGAGACAAGAATATTTTATTGAAAAATATATGGATATATTACCTTGCAATATATTTATGGGTGTTGGAGGAAGTTTTGA
TATATTTTCAGGTATTTCTAAAAGAGCACCTAAATGGATGATAAATTTAGGGCTTGAATGGCTTTACAGGGTGACAAAGG
AACCTTGGAGAATAACAAGACTTACTTCTATACCTAAATTTTTAATAAAAGTATTAAAGTACAATAAAAGGTGA

Upstream 100 bases:

>100_bases
AAGTATTTAAGGACTTTCAATAAAAATGTAAACTCTTAATTTCTAATTTTTAGTTGAAAAGCGTGACGTAATAAACTTTG
CAATTTAAGTAGTGAATTTT

Downstream 100 bases:

>100_bases
TAAATATGAAGAAGAATGCTTTGTTAAAATCTACTTTAATAATAATGATAGTATCATGTATAAGTAGAATTATAGGTTTT
GTTAGAGATATGCTTATTGC

Product: glycosyl transferase, WecB/TagA/CpsF family

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MFTDILNFKIFNGSKKELMKYIEKFEKINIISGNPEILFNGLNNKILNRCFKEDNSVIIPDGVGTVLASKLLKNPVKEKI
AGIEVMKELLSKANLENKSIYLLGAKEEVIQKCGENIKNEFNNLDICGLHNGYFDLDSCAEIIDEIKEKKPWVIFIAMGC
PRQEYFIEKYMDILPCNIFMGVGGSFDIFSGISKRAPKWMINLGLEWLYRVTKEPWRITRLTSIPKFLIKVLKYNKR

Sequences:

>Translated_237_residues
MFTDILNFKIFNGSKKELMKYIEKFEKINIISGNPEILFNGLNNKILNRCFKEDNSVIIPDGVGTVLASKLLKNPVKEKI
AGIEVMKELLSKANLENKSIYLLGAKEEVIQKCGENIKNEFNNLDICGLHNGYFDLDSCAEIIDEIKEKKPWVIFIAMGC
PRQEYFIEKYMDILPCNIFMGVGGSFDIFSGISKRAPKWMINLGLEWLYRVTKEPWRITRLTSIPKFLIKVLKYNKR
>Mature_237_residues
MFTDILNFKIFNGSKKELMKYIEKFEKINIISGNPEILFNGLNNKILNRCFKEDNSVIIPDGVGTVLASKLLKNPVKEKI
AGIEVMKELLSKANLENKSIYLLGAKEEVIQKCGENIKNEFNNLDICGLHNGYFDLDSCAEIIDEIKEKKPWVIFIAMGC
PRQEYFIEKYMDILPCNIFMGVGGSFDIFSGISKRAPKWMINLGLEWLYRVTKEPWRITRLTSIPKFLIKVLKYNKR

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=160, Percent_Identity=35, Blast_Score=112, Evalue=1e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 27344; Mature: 27344

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTDILNFKIFNGSKKELMKYIEKFEKINIISGNPEILFNGLNNKILNRCFKEDNSVIIP
CCCCEEEEEEECCCHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHHCCCCEECC
DGVGTVLASKLLKNPVKEKIAGIEVMKELLSKANLENKSIYLLGAKEEVIQKCGENIKNE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHH
FNNLDICGLHNGYFDLDSCAEIIDEIKEKKPWVIFIAMGCPRQEYFIEKYMDILPCNIFM
HCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCHHHEE
GVGGSFDIFSGISKRAPKWMINLGLEWLYRVTKEPWRITRLTSIPKFLIKVLKYNKR
ECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTDILNFKIFNGSKKELMKYIEKFEKINIISGNPEILFNGLNNKILNRCFKEDNSVIIP
CCCCEEEEEEECCCHHHHHHHHHHHHHEEEECCCCCEEEECCCHHHHHHHHHCCCCEECC
DGVGTVLASKLLKNPVKEKIAGIEVMKELLSKANLENKSIYLLGAKEEVIQKCGENIKNE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHHH
FNNLDICGLHNGYFDLDSCAEIIDEIKEKKPWVIFIAMGCPRQEYFIEKYMDILPCNIFM
HCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHCHHHEE
GVGGSFDIFSGISKRAPKWMINLGLEWLYRVTKEPWRITRLTSIPKFLIKVLKYNKR
ECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 9384377; 11882717 [H]