Click here to switch to the map view.

The map label for this gene is metA [H]

Identifier: 187934877

GI number: 187934877

Start: 2995194

End: 2996114

Strand: Reverse

Name: metA [H]

Synonym: CLL_A2913

Alternate gene names: 187934877

Gene position: 2996114-2995194 (Counterclockwise)

Preceding gene: 187932824

Following gene: 187934973

Centisome position: 78.84

GC content: 26.71

Gene sequence:

>921_bases
GTGCCTATAAAAATTCCAACAGAATTACCAGCATTTAAAGTATTATCTAACGAAAATATTTTTGTCATGAATGATAGTAG
AGCAAAGACTCAAGATATAAGACCATTAAAGATTGCAATTCTTAATTTAATGCCGAAAAAAATTTTAGCAGAAAATCAAT
TATTGAGGCACTTATCTAATACACCATTACAAGTTGAAGTAAAGCTTATTCAAACTAAAAGTTATGTTTCACAAAATACG
CCAATTGAACATTTGGAAAAGTTTTATACTTATTTTGATGATATAAAAGATGAAAAATTTGATGGATTAATAATAACTGG
GGCACCTGTTGAACAAATGGCATTTGAGGATATTACTTATTGGAACGAATTAACTGAAATTATGAAATGGAGTAAATCAA
ATGTTTTTTCAACATTACATATATGTTGGGGGGCTCAAGCAGGATTATATTATCATTATGATATACAAAAATATAAATTA
GAAAAGAAAATATCTGGTGTATTTTCTCATTGGGTAAATGACGAAAATGCTGATTTAACAAGAGGATTAGATGATATATT
TTATGTACCACACTCTAGACATACAGAAGTAAAAAAAGAAGATATAAATAAAATTTCAGAATTAGAAATTTTATCAGAAT
CTAAAGAGGCAGGTATCTTTATTGTAGCTACTAAAGATAGAAGAAAAATATTCTTTATGGGTCATCCTGAGTATGATAGA
AATACATTGAAAGAAGAATATATGAGAGATAGAGAAAAGGGAGATAATGTAGATATACCACAAAACTATTTTGTAGATAA
TGATATAAATAGTACTCCTAAATTTACATGGAGAGGTAGCTCTAATATAATATTTGGCAATTGGTTAAATTATTGTGTAT
ATCAAAATACTCCTTATGATATTAATGATATATCTAAATAA

Upstream 100 bases:

>100_bases
TAAATATTAATTTTTTGGTATAATAATTTGTAAATAACAAAAATTAAATAATGATTTTAAAAGATATGTAAAAGCGCAAA
TAAGAAGGGGGGCTTTATTA

Downstream 100 bases:

>100_bases
AAATGTATTTATGTTTTAGGTAACAGATTGGGCTTTCGGTTGCTAAAAACAAATTCACAAGAATGTTTATATTAAAAATT
ACATAAATATTAACAATACA

Product: homoserine O-succinyltransferase

Products: NA

Alternate protein names: Homoserine O-transsuccinylase; HTS [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MPIKIPTELPAFKVLSNENIFVMNDSRAKTQDIRPLKIAILNLMPKKILAENQLLRHLSNTPLQVEVKLIQTKSYVSQNT
PIEHLEKFYTYFDDIKDEKFDGLIITGAPVEQMAFEDITYWNELTEIMKWSKSNVFSTLHICWGAQAGLYYHYDIQKYKL
EKKISGVFSHWVNDENADLTRGLDDIFYVPHSRHTEVKKEDINKISELEILSESKEAGIFIVATKDRRKIFFMGHPEYDR
NTLKEEYMRDREKGDNVDIPQNYFVDNDINSTPKFTWRGSSNIIFGNWLNYCVYQNTPYDINDISK

Sequences:

>Translated_306_residues
MPIKIPTELPAFKVLSNENIFVMNDSRAKTQDIRPLKIAILNLMPKKILAENQLLRHLSNTPLQVEVKLIQTKSYVSQNT
PIEHLEKFYTYFDDIKDEKFDGLIITGAPVEQMAFEDITYWNELTEIMKWSKSNVFSTLHICWGAQAGLYYHYDIQKYKL
EKKISGVFSHWVNDENADLTRGLDDIFYVPHSRHTEVKKEDINKISELEILSESKEAGIFIVATKDRRKIFFMGHPEYDR
NTLKEEYMRDREKGDNVDIPQNYFVDNDINSTPKFTWRGSSNIIFGNWLNYCVYQNTPYDINDISK
>Mature_305_residues
PIKIPTELPAFKVLSNENIFVMNDSRAKTQDIRPLKIAILNLMPKKILAENQLLRHLSNTPLQVEVKLIQTKSYVSQNTP
IEHLEKFYTYFDDIKDEKFDGLIITGAPVEQMAFEDITYWNELTEIMKWSKSNVFSTLHICWGAQAGLYYHYDIQKYKLE
KKISGVFSHWVNDENADLTRGLDDIFYVPHSRHTEVKKEDINKISELEILSESKEAGIFIVATKDRRKIFFMGHPEYDRN
TLKEEYMRDREKGDNVDIPQNYFVDNDINSTPKFTWRGSSNIIFGNWLNYCVYQNTPYDINDISK

Specific function: Methionine biosynthesis; HTS variant; first step. [C]

COG id: COG1897

COG function: function code E; Homoserine trans-succinylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HTS family [H]

Homologues:

Organism=Escherichia coli, GI1790443, Length=305, Percent_Identity=50.4918032786885, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005697
- ProDom:   PD037892 [H]

Pfam domain/function: PF04204 HTS [H]

EC number: =2.3.1.46 [H]

Molecular weight: Translated: 35927; Mature: 35796

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIKIPTELPAFKVLSNENIFVMNDSRAKTQDIRPLKIAILNLMPKKILAENQLLRHLSN
CCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
TPLQVEVKLIQTKSYVSQNTPIEHLEKFYTYFDDIKDEKFDGLIITGAPVEQMAFEDITY
CCEEEEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
WNELTEIMKWSKSNVFSTLHICWGAQAGLYYHYDIQKYKLEKKISGVFSHWVNDENADLT
HHHHHHHHHHCCCCHHHEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCHHH
RGLDDIFYVPHSRHTEVKKEDINKISELEILSESKEAGIFIVATKDRRKIFFMGHPEYDR
CCCHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCH
NTLKEEYMRDREKGDNVDIPQNYFVDNDINSTPKFTWRGSSNIIFGNWLNYCVYQNTPYD
HHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEECCCCCEEEECCCCEEEECCCCCC
INDISK
HHCCCC
>Mature Secondary Structure 
PIKIPTELPAFKVLSNENIFVMNDSRAKTQDIRPLKIAILNLMPKKILAENQLLRHLSN
CCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
TPLQVEVKLIQTKSYVSQNTPIEHLEKFYTYFDDIKDEKFDGLIITGAPVEQMAFEDITY
CCEEEEEEEEEEHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHH
WNELTEIMKWSKSNVFSTLHICWGAQAGLYYHYDIQKYKLEKKISGVFSHWVNDENADLT
HHHHHHHHHHCCCCHHHEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHCCCCCCHHH
RGLDDIFYVPHSRHTEVKKEDINKISELEILSESKEAGIFIVATKDRRKIFFMGHPEYDR
CCCHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCH
NTLKEEYMRDREKGDNVDIPQNYFVDNDINSTPKFTWRGSSNIIFGNWLNYCVYQNTPYD
HHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCCEEECCCCCEEEECCCCEEEECCCCCC
INDISK
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA