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The map label for this gene is lytA [H]

Identifier: 187934866

GI number: 187934866

Start: 3624124

End: 3625473

Strand: Reverse

Name: lytA [H]

Synonym: CLL_A3432

Alternate gene names: 187934866

Gene position: 3625473-3624124 (Counterclockwise)

Preceding gene: 187935408

Following gene: 187933350

Centisome position: 95.4

GC content: 30.44

Gene sequence:

>1350_bases
ATGAAAAGTGCTAGATTAAAAAAGATTACAGCGGCAGTAATGGCACTATCAATTATAGCTTCTGTATCTCCTGTTGGAGC
ATCAGCAGCATGGAAGCAAGATAATAATGGATGGTGGAATGATAAGGAAAGCTCTTATTCTGTTGGTTGGGAAAATATAA
ATAATACATGGTATTATTTTAATCAAGATGGTTATATGAAAACAGGATGGGTAAATGATAATGGAGCATGGTATTATACA
GATGCTTCAGGTGCAATGAAGACAGGCTGGGTCAATGATGGTGGAAATTGGTACTATACTTCTCAAAGTGGATCAATGCA
AACAGGATGGATTAATGATAATGGGTCATGGTATTATACAGATAATTCAGGTTCAATGAAAACTGGTTGGGTAAGTGACA
ATGGAAAATGGTACTATACATCATCAAATGGAGCAATGCAAACTGGTGTAGTTAAGGTTGATAATAAGGTTTATTCATTA
GGACAAAATGGAGAAATGCAAAAAGGAAATGTGGTTATTGAAGGAAAAACATATACCTTCTCTGAGAGTGGAGAGTGTGT
AAGTAGCGAAATCCCTAAGATAGCCAAGGAATTTGCGCCAGGAAATATAGATATAACTACAAATCAAAATGCAAATAACA
CTACTAACAATAATTCTGGAACTGAACAAAAAAATGATACTGAAAAAGTTAATGATAATACAGAAAAGAAATCAGGTGGT
GGATCTAAGCATCATAATAGCTCAACAGATTCATATCAATCTAAATTAAATATAGATAAACAAGATGTATCTTTTAATTA
TGAAATTAAAAATAATGCTGAATATGATGTGAAGTGTGATCTTTATAATTCAAATAATAAGATTGTAGATACTATAAAGT
GGGATAAGCCTGATAAATTAAGTGGATCAAATGCTAATATATATATAACTGATATATTAGGGGAAATGAATGCAAATGAT
TATATAGTATCACAAATTAAAAATAATAAAGGTACAATCCTTAAGTCATCTAAGATGCAGGTTGTAAGTAAAGATAAATT
GACTAATGAAATAATTAATGCATCTACTAAAAAAGAAGATAGTAAATTCAATTGTACAGTTCAAGGCAAAGAAAATTTTG
CAGCAGGAACTTATGTATTATATGGATTTGAATCTGATAGTAATGCATATGTAAAAACTGTTTACTGTGATGGAAATACT
AATACATTGGAATTTAAGAATGTAGGTTATAACTGGATTAAAAATGGAACAGGTAAGATAAAGCTTGCAAGAGTTTATGA
TACTCAAAAAGTAAATGATAACTTAGGAAACTGTAAGGTTCAAGTTTCTGATTATTTTACTATGAAGTAA

Upstream 100 bases:

>100_bases
TAAGTTTAATGGTAGTTTAAGAAAGTTATTTTTATTAAATTTAAAAGTTAAGTGAATTTTAAAATAATATGAGTTGAAAT
TATGGAAGGGGTAAAATTTT

Downstream 100 bases:

>100_bases
GTCTAGAACTCATAGGGATAAAAGTATTTGAGAATTGAGAGGAGGAATATTATTTAAGGAAAAACTATATAATAAAAGGC
CTTGTTTTAAATAGATGTTG

Product: surface protein PspC

Products: NA

Alternate protein names: Cell wall hydrolase; Mucopeptide aminohydrolase; Murein hydrolase; N-acetylmuramoyl-L-alanine amidase [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKSARLKKITAAVMALSIIASVSPVGASAAWKQDNNGWWNDKESSYSVGWENINNTWYYFNQDGYMKTGWVNDNGAWYYT
DASGAMKTGWVNDGGNWYYTSQSGSMQTGWINDNGSWYYTDNSGSMKTGWVSDNGKWYYTSSNGAMQTGVVKVDNKVYSL
GQNGEMQKGNVVIEGKTYTFSESGECVSSEIPKIAKEFAPGNIDITTNQNANNTTNNNSGTEQKNDTEKVNDNTEKKSGG
GSKHHNSSTDSYQSKLNIDKQDVSFNYEIKNNAEYDVKCDLYNSNNKIVDTIKWDKPDKLSGSNANIYITDILGEMNAND
YIVSQIKNNKGTILKSSKMQVVSKDKLTNEIINASTKKEDSKFNCTVQGKENFAAGTYVLYGFESDSNAYVKTVYCDGNT
NTLEFKNVGYNWIKNGTGKIKLARVYDTQKVNDNLGNCKVQVSDYFTMK

Sequences:

>Translated_449_residues
MKSARLKKITAAVMALSIIASVSPVGASAAWKQDNNGWWNDKESSYSVGWENINNTWYYFNQDGYMKTGWVNDNGAWYYT
DASGAMKTGWVNDGGNWYYTSQSGSMQTGWINDNGSWYYTDNSGSMKTGWVSDNGKWYYTSSNGAMQTGVVKVDNKVYSL
GQNGEMQKGNVVIEGKTYTFSESGECVSSEIPKIAKEFAPGNIDITTNQNANNTTNNNSGTEQKNDTEKVNDNTEKKSGG
GSKHHNSSTDSYQSKLNIDKQDVSFNYEIKNNAEYDVKCDLYNSNNKIVDTIKWDKPDKLSGSNANIYITDILGEMNAND
YIVSQIKNNKGTILKSSKMQVVSKDKLTNEIINASTKKEDSKFNCTVQGKENFAAGTYVLYGFESDSNAYVKTVYCDGNT
NTLEFKNVGYNWIKNGTGKIKLARVYDTQKVNDNLGNCKVQVSDYFTMK
>Mature_449_residues
MKSARLKKITAAVMALSIIASVSPVGASAAWKQDNNGWWNDKESSYSVGWENINNTWYYFNQDGYMKTGWVNDNGAWYYT
DASGAMKTGWVNDGGNWYYTSQSGSMQTGWINDNGSWYYTDNSGSMKTGWVSDNGKWYYTSSNGAMQTGVVKVDNKVYSL
GQNGEMQKGNVVIEGKTYTFSESGECVSSEIPKIAKEFAPGNIDITTNQNANNTTNNNSGTEQKNDTEKVNDNTEKKSGG
GSKHHNSSTDSYQSKLNIDKQDVSFNYEIKNNAEYDVKCDLYNSNNKIVDTIKWDKPDKLSGSNANIYITDILGEMNAND
YIVSQIKNNKGTILKSSKMQVVSKDKLTNEIINASTKKEDSKFNCTVQGKENFAAGTYVLYGFESDSNAYVKTVYCDGNT
NTLEFKNVGYNWIKNGTGKIKLARVYDTQKVNDNLGNCKVQVSDYFTMK

Specific function: Autolysins are involved in some important biological processes such as cell separation, cell-wall turnover, competence for genetic transformation, formation of the flagella and sporulation. Autolysin strictly depends on the presence of choline-containing

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 6 cell wall-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002502
- InterPro:   IPR018337 [H]

Pfam domain/function: PF01510 Amidase_2; PF01473 CW_binding_1 [H]

EC number: =3.5.1.28 [H]

Molecular weight: Translated: 50034; Mature: 50034

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSARLKKITAAVMALSIIASVSPVGASAAWKQDNNGWWNDKESSYSVGWENINNTWYYF
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEECCCCCCCEEEEE
NQDGYMKTGWVNDNGAWYYTDASGAMKTGWVNDGGNWYYTSQSGSMQTGWINDNGSWYYT
CCCCEEEEEEECCCCCEEEECCCCCEEECEECCCCCEEEECCCCCEEEEEECCCCCEEEE
DNSGSMKTGWVSDNGKWYYTSSNGAMQTGVVKVDNKVYSLGQNGEMQKGNVVIEGKTYTF
CCCCCEEEEEECCCCEEEEECCCCCEEECEEEECCEEEECCCCCCCCCCCEEEECCEEEE
SESGECVSSEIPKIAKEFAPGNIDITTNQNANNTTNNNSGTEQKNDTEKVNDNTEKKSGG
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCC
GSKHHNSSTDSYQSKLNIDKQDVSFNYEIKNNAEYDVKCDLYNSNNKIVDTIKWDKPDKL
CCCCCCCCCCHHHHHCCCCHHHCEEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCCCC
SGSNANIYITDILGEMNANDYIVSQIKNNKGTILKSSKMQVVSKDKLTNEIINASTKKED
CCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEECCCEEEEEHHHHHHHHHCCCCCCCC
SKFNCTVQGKENFAAGTYVLYGFESDSNAYVKTVYCDGNTNTLEFKNVGYNWIKNGTGKI
CEEEEEEECCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCEE
KLARVYDTQKVNDNLGNCKVQVSDYFTMK
EEEEEECCCCCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MKSARLKKITAAVMALSIIASVSPVGASAAWKQDNNGWWNDKESSYSVGWENINNTWYYF
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEECCCCCCCEEEEE
NQDGYMKTGWVNDNGAWYYTDASGAMKTGWVNDGGNWYYTSQSGSMQTGWINDNGSWYYT
CCCCEEEEEEECCCCCEEEECCCCCEEECEECCCCCEEEECCCCCEEEEEECCCCCEEEE
DNSGSMKTGWVSDNGKWYYTSSNGAMQTGVVKVDNKVYSLGQNGEMQKGNVVIEGKTYTF
CCCCCEEEEEECCCCEEEEECCCCCEEECEEEECCEEEECCCCCCCCCCCEEEECCEEEE
SESGECVSSEIPKIAKEFAPGNIDITTNQNANNTTNNNSGTEQKNDTEKVNDNTEKKSGG
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCC
GSKHHNSSTDSYQSKLNIDKQDVSFNYEIKNNAEYDVKCDLYNSNNKIVDTIKWDKPDKL
CCCCCCCCCCHHHHHCCCCHHHCEEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCCCC
SGSNANIYITDILGEMNANDYIVSQIKNNKGTILKSSKMQVVSKDKLTNEIINASTKKED
CCCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEECCCEEEEEHHHHHHHHHCCCCCCCC
SKFNCTVQGKENFAAGTYVLYGFESDSNAYVKTVYCDGNTNTLEFKNVGYNWIKNGTGKI
CEEEEEEECCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCCEEECCCCEE
KLARVYDTQKVNDNLGNCKVQVSDYFTMK
EEEEEECCCCCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2875013; 11463916 [H]