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The map label for this gene is yrvM [H]

Identifier: 187933350

GI number: 187933350

Start: 3622133

End: 3622900

Strand: Reverse

Name: yrvM [H]

Synonym: CLL_A3430

Alternate gene names: 187933350

Gene position: 3622900-3622133 (Counterclockwise)

Preceding gene: 187934866

Following gene: 187932398

Centisome position: 95.33

GC content: 29.04

Gene sequence:

>768_bases
ATGTTAGAACATTCTTTAGTAAGAACAGAATTATTAGTAGGAAAAGATAGTTTAGATAAATTAAAAAATAGTAAGGTAAT
GATTTTTGGAATTGGTGGGGTAGGAAGCTTTACTGTTGAAGCACTTGCAAGATCAGGTGTTGGTGAACTTATACTAGTTG
ACAATGACACAATTTCATTAACAAACTTAAACAGACAAATCCATGCTACATACAATACAATAGATGAACCTAAAGTTGAG
GCAATGAAGGAAAGAATTCTTTCTATAAATAAGGATTGCAATGTTATTACTCATCAAACATTTGTTAATAGAGATAATAT
ACCTGAAATAATTCCAGCAGATGTTGATTATATAGTAGATGCAATAGACACAGTAACATCAAAACTTGCTTTAGCAGAAC
ATTGTTATAAAAATAATATAAGAATAATGAGTTCTATGGGAACAGGAAATAAATTAGATCCTACACAATTTAAAGTTACT
GATGTATTTAAAACAAAGGTATGCCCTTTAGCAAAAGTAATGAGATGTGAACTTAAAAAAAGAGGCGTAGAAAAATTAAA
AGTAGTTTATTCAGAAGAAATGCCACTAAGACCTAGTGTTGATAATAGTGTAGCTTGTAATTCTGAAGCAAATGATAATG
GAACTGATGAAAATAAAATAGTAATAAAGAAAAGACAAACACCAGGAAGTATGTCTTTTGTACCACCAGTTGCAGGAATG
ATAATTGCAGGAGAAGTTATAAAAGATATTTTAAATATTAAGAAATAA

Upstream 100 bases:

>100_bases
TAATGAGCTAAGTATTTCATAGTATAATTTATCTTGTTATATAAGAAACTATGAGTATTTGAAACAAATATTAACTAAGA
GCATGAAGGAGATACAAAAA

Downstream 100 bases:

>100_bases
AATATAAAATTTATTTTATCCACAGCATAAGTAGTTTTAAATGTTTTACAAGTTAAATAACTGAAATAAGTGTATAATAT
CTAATTATTCTACTTATGTG

Product: thiF domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MLEHSLVRTELLVGKDSLDKLKNSKVMIFGIGGVGSFTVEALARSGVGELILVDNDTISLTNLNRQIHATYNTIDEPKVE
AMKERILSINKDCNVITHQTFVNRDNIPEIIPADVDYIVDAIDTVTSKLALAEHCYKNNIRIMSSMGTGNKLDPTQFKVT
DVFKTKVCPLAKVMRCELKKRGVEKLKVVYSEEMPLRPSVDNSVACNSEANDNGTDENKIVIKKRQTPGSMSFVPPVAGM
IIAGEVIKDILNIKK

Sequences:

>Translated_255_residues
MLEHSLVRTELLVGKDSLDKLKNSKVMIFGIGGVGSFTVEALARSGVGELILVDNDTISLTNLNRQIHATYNTIDEPKVE
AMKERILSINKDCNVITHQTFVNRDNIPEIIPADVDYIVDAIDTVTSKLALAEHCYKNNIRIMSSMGTGNKLDPTQFKVT
DVFKTKVCPLAKVMRCELKKRGVEKLKVVYSEEMPLRPSVDNSVACNSEANDNGTDENKIVIKKRQTPGSMSFVPPVAGM
IIAGEVIKDILNIKK
>Mature_255_residues
MLEHSLVRTELLVGKDSLDKLKNSKVMIFGIGGVGSFTVEALARSGVGELILVDNDTISLTNLNRQIHATYNTIDEPKVE
AMKERILSINKDCNVITHQTFVNRDNIPEIIPADVDYIVDAIDTVTSKLALAEHCYKNNIRIMSSMGTGNKLDPTQFKVT
DVFKTKVCPLAKVMRCELKKRGVEKLKVVYSEEMPLRPSVDNSVACNSEANDNGTDENKIVIKKRQTPGSMSFVPPVAGM
IIAGEVIKDILNIKK

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Escherichia coli, GI1789177, Length=214, Percent_Identity=38.3177570093458, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI87082356, Length=142, Percent_Identity=30.9859154929577, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787048, Length=130, Percent_Identity=32.3076923076923, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17540406, Length=125, Percent_Identity=31.2, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321790, Length=256, Percent_Identity=29.296875, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322825, Length=198, Percent_Identity=36.8686868686869, Blast_Score=102, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6321903, Length=132, Percent_Identity=31.0606060606061, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24582879, Length=116, Percent_Identity=33.6206896551724, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28174; Mature: 28174

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEHSLVRTELLVGKDSLDKLKNSKVMIFGIGGVGSFTVEALARSGVGELILVDNDTISL
CCCHHHHHHHHHHCCHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCEEEE
TNLNRQIHATYNTIDEPKVEAMKERILSINKDCNVITHQTFVNRDNIPEIIPADVDYIVD
EECCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEHEECCCCCCCCCCCCCHHHHHH
AIDTVTSKLALAEHCYKNNIRIMSSMGTGNKLDPTQFKVTDVFKTKVCPLAKVMRCELKK
HHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
RGVEKLKVVYSEEMPLRPSVDNSVACNSEANDNGTDENKIVIKKRQTPGSMSFVPPVAGM
CCHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHH
IIAGEVIKDILNIKK
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MLEHSLVRTELLVGKDSLDKLKNSKVMIFGIGGVGSFTVEALARSGVGELILVDNDTISL
CCCHHHHHHHHHHCCHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEEECCEEEE
TNLNRQIHATYNTIDEPKVEAMKERILSINKDCNVITHQTFVNRDNIPEIIPADVDYIVD
EECCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEHEECCCCCCCCCCCCCHHHHHH
AIDTVTSKLALAEHCYKNNIRIMSSMGTGNKLDPTQFKVTDVFKTKVCPLAKVMRCELKK
HHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
RGVEKLKVVYSEEMPLRPSVDNSVACNSEANDNGTDENKIVIKKRQTPGSMSFVPPVAGM
CCHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEECCCCCCCCCCCHHHHH
IIAGEVIKDILNIKK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]