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The map label for this gene is manA [H]

Identifier: 187934703

GI number: 187934703

Start: 2151520

End: 2152455

Strand: Reverse

Name: manA [H]

Synonym: CLL_A2057

Alternate gene names: 187934703

Gene position: 2152455-2151520 (Counterclockwise)

Preceding gene: 187933726

Following gene: 187935739

Centisome position: 56.64

GC content: 29.27

Gene sequence:

>936_bases
ATGTATCCAATTAAATTTAAAAATATATATTATGAAAAAATATGGGGAGGAAGAGACTTAGCACAGTTTAGAGATAACCT
TCCTTTAGGAGATATAGGTGAAAGTTGGGATGTAGCATGTCATTCAAATGGTATGAGCATAGTTGAAAATGGTGAATTAA
AAGGTAAGAGATTTGATGAACTTATAAAAGAATATGGTAAAGATTTATTAGGAGAAAGTTTTGAAAATAAGGACTTTCCA
CTATTAGTTAAGTTAATAAATTCAAGAGAAAAGCTATCAGTACAAGTGCATCCTAATGATGAATATGCTAATAGAGTAGA
AAATTCATTAGGAAAGACAGAAGCTTGGTATGTAGTGGATGCAAAGCCAGGAGCTTGTTTAATAGTTGGAACAAAGGATT
GCAATAAGGCAGTTTTTGAAAAGGCTATAAAAGAAGGTAAAACAGAAGATTATTTAAACAAGATACAAGTTAAAAAGGGC
GATTGCTTCCTTATAAATAGTGGTTTAGTACATGCTATTTGTGAAGGAGTTATTATAGCTGAAATCCAACAAAATAGTGA
TATAACTTATAGAATATATGATTATGGTAGACCAAGAGAAATTCATGTTGATAAGTCTTTAGATGTTATTGATTTTGGAT
TAAAGGCAATGAATTTTAGTGAAAATAAGCTAGACAGTTATGATGGTTATAAAAAAGGTGTTCTTTGTTCAAGTGAATAT
TTTACCATGGAAAAGTATGTTGTTAATGGAGAAGTAGAGGAAAGCAGTGATATAAATAAATTCTTTATATTTACCTGTGT
AGATGGTAATGGATTTATTAAATCATTACATGGACATGATATTGAAGTCCTTAAAGGTGACAGCATATTAATACCAGCTA
AATTAGGTAAGTACGTTATAGAAGGAAACTTAACTTTATTAAAAAGTTATATTTAG

Upstream 100 bases:

>100_bases
ATAAGTGGATCATTAAAAATAATAATAAAAGTAATGTTAATTATAAATTTAAATAGTTTTCCATTAAATTTTACAACTAC
ATTATACAAGGAGTGATAAT

Downstream 100 bases:

>100_bases
GAGGGCAAACATGAAATATTACATAGGTATAGATATAGGCGGAACAAACTTAAGAGCAGCAATATTAGATGAAAAATGTA
ACTTAGTAGATAAGCTTAAA

Product: mannose-6-phosphate isomerase, class I

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MYPIKFKNIYYEKIWGGRDLAQFRDNLPLGDIGESWDVACHSNGMSIVENGELKGKRFDELIKEYGKDLLGESFENKDFP
LLVKLINSREKLSVQVHPNDEYANRVENSLGKTEAWYVVDAKPGACLIVGTKDCNKAVFEKAIKEGKTEDYLNKIQVKKG
DCFLINSGLVHAICEGVIIAEIQQNSDITYRIYDYGRPREIHVDKSLDVIDFGLKAMNFSENKLDSYDGYKKGVLCSSEY
FTMEKYVVNGEVEESSDINKFFIFTCVDGNGFIKSLHGHDIEVLKGDSILIPAKLGKYVIEGNLTLLKSYI

Sequences:

>Translated_311_residues
MYPIKFKNIYYEKIWGGRDLAQFRDNLPLGDIGESWDVACHSNGMSIVENGELKGKRFDELIKEYGKDLLGESFENKDFP
LLVKLINSREKLSVQVHPNDEYANRVENSLGKTEAWYVVDAKPGACLIVGTKDCNKAVFEKAIKEGKTEDYLNKIQVKKG
DCFLINSGLVHAICEGVIIAEIQQNSDITYRIYDYGRPREIHVDKSLDVIDFGLKAMNFSENKLDSYDGYKKGVLCSSEY
FTMEKYVVNGEVEESSDINKFFIFTCVDGNGFIKSLHGHDIEVLKGDSILIPAKLGKYVIEGNLTLLKSYI
>Mature_311_residues
MYPIKFKNIYYEKIWGGRDLAQFRDNLPLGDIGESWDVACHSNGMSIVENGELKGKRFDELIKEYGKDLLGESFENKDFP
LLVKLINSREKLSVQVHPNDEYANRVENSLGKTEAWYVVDAKPGACLIVGTKDCNKAVFEKAIKEGKTEDYLNKIQVKKG
DCFLINSGLVHAICEGVIIAEIQQNSDITYRIYDYGRPREIHVDKSLDVIDFGLKAMNFSENKLDSYDGYKKGVLCSSEY
FTMEKYVVNGEVEESSDINKFFIFTCVDGNGFIKSLHGHDIEVLKGDSILIPAKLGKYVIEGNLTLLKSYI

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 35209; Mature: 35209

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPIKFKNIYYEKIWGGRDLAQFRDNLPLGDIGESWDVACHSNGMSIVENGELKGKRFDE
CCCEEECCEEEEHHCCCCHHHHHHCCCCCCCCCCCCCEEECCCCCEEEECCCCCCHHHHH
LIKEYGKDLLGESFENKDFPLLVKLINSREKLSVQVHPNDEYANRVENSLGKTEAWYVVD
HHHHHHHHHHCCCCCCCCCHHHHEECCCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEEE
AKPGACLIVGTKDCNKAVFEKAIKEGKTEDYLNKIQVKKGDCFLINSGLVHAICEGVIIA
CCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHEEEECCCEEEECCCHHHHHHCCEEEE
EIQQNSDITYRIYDYGRPREIHVDKSLDVIDFGLKAMNFSENKLDSYDGYKKGVLCSSEY
EEECCCCEEEEEEECCCCEEEEECCCCCEEECCHHHCCCCCCCCCCCCCCCCCEEECCCC
FTMEKYVVNGEVEESSDINKFFIFTCVDGNGFIKSLHGHDIEVLKGDSILIPAKLGKYVI
EEEEEEEECCCCCCCCCCCEEEEEEEECCCCEEEECCCCEEEEEECCCEEEECCCCCEEE
EGNLTLLKSYI
ECCCEEEEECC
>Mature Secondary Structure
MYPIKFKNIYYEKIWGGRDLAQFRDNLPLGDIGESWDVACHSNGMSIVENGELKGKRFDE
CCCEEECCEEEEHHCCCCHHHHHHCCCCCCCCCCCCCEEECCCCCEEEECCCCCCHHHHH
LIKEYGKDLLGESFENKDFPLLVKLINSREKLSVQVHPNDEYANRVENSLGKTEAWYVVD
HHHHHHHHHHCCCCCCCCCHHHHEECCCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEEE
AKPGACLIVGTKDCNKAVFEKAIKEGKTEDYLNKIQVKKGDCFLINSGLVHAICEGVIIA
CCCCEEEEEECCCHHHHHHHHHHHCCCCHHHHHHEEEECCCEEEECCCHHHHHHCCEEEE
EIQQNSDITYRIYDYGRPREIHVDKSLDVIDFGLKAMNFSENKLDSYDGYKKGVLCSSEY
EEECCCCEEEEEEECCCCEEEEECCCCCEEECCHHHCCCCCCCCCCCCCCCCCEEECCCC
FTMEKYVVNGEVEESSDINKFFIFTCVDGNGFIKSLHGHDIEVLKGDSILIPAKLGKYVI
EEEEEEEECCCCCCCCCCCEEEEEEEECCCCEEEECCCCEEEEEECCCEEEECCCCCEEE
EGNLTLLKSYI
ECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8293960; 12397186 [H]