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The map label for this gene is flp [H]

Identifier: 187934502

GI number: 187934502

Start: 2186948

End: 2188411

Strand: Reverse

Name: flp [H]

Synonym: CLL_A2089

Alternate gene names: 187934502

Gene position: 2188411-2186948 (Counterclockwise)

Preceding gene: 187934839

Following gene: 187933294

Centisome position: 57.58

GC content: 27.19

Gene sequence:

>1464_bases
ATGAGCAACATAATGAAAAGAAAAAAGAATCTATTGAAAAGTGTAATTTTAATAGTTGCATTAATGGGAATTGCTTTTAG
CGTATTTAATGTAATTAAAAATAAAGACAATGATTACATAGATAAATTAATAGAAAAATATAGTCCACAAGGGGCAGCAA
TAGCAGTAATTGAAAATGGTGAGATTACTGAAGTAAGAAATTATGGATATTCAAATATTGAAAGTAAAAGTTTAGTTAAT
AATGAAACACAATTTAAAATAGCATCTATATCAAAAAGCATAACATCATATGCAGTAATGAAATTAGTAGATGAAGGAAA
ATTGAATTTGGATGAACCAATCAACACATATTTAACAAAATGGAAAATACCAGACACGGAGTTTGATGAAAATAAATTAA
CACTTAGAACGTTAATGTCACATACAAGTGGGATTACAGGAAGTAATGAAATTGGGTATGAGTCCCCATTGCCAACAATA
GAAGATGCTTTAAAAATTAGAGATATAAAACTAAAAAGAGAACCAGGAGAGGTTTTTGAGTATTCTGAATTTGCAGGACT
AGGCATATGTCAACTAATTATTGAAGAAGTAACTGGCGAAAAATTTGAAAAGTATATGGAAGATGAAGTATTTAAAAAAC
TAGGTATGAATAACACCAATTATGATAATGAAATTGGAGATAATTTATTAGCTGTGCCATATGCAGGAATAAATAAGCAA
ATTAAAGTTACACCAATTGTAATGAATGGTGGTGGAGGGGTTTCTACAACAGCAAGTGATTTAGCAAAATTCACAATAGA
ATTAATTAATTATCATAATAATGGCGATGGTGAAATGTTTAAAGCTCAAAAAAATACTGAAAGTGTTGGTGGTAAATATG
GATTGGGTATTATACCAAGAGAACTTAAAAATGGAAAAACAGTATATGAGCATAATGGAACATTAACTGGTTGGAATGCA
CAAATGGTAATGGAACCAATTAGTAAGGATGGAATTGTAATTCTTACTAACTCTGATAAAGCATTTTTTCTAACATATGA
ATTAATGGAAAAATGGGGCGAAAAAGCAGTAGGAGAAAAGGTTATAGATACAAAAATTAACACACTTGTAGATATGGTAT
ATAAATGTATAGCAGTATTATGTGCAATCTTAACTTTACTTATAATTATTTTTATTATTAAAGTTAAAAAATGTAAAATT
GTTTTACTTGAAAGAAAAAAACGTAATAGGAAATATTTAATATCAGCTATATTTTGTACACTTTTAGCAGTAATATATTT
TGTAAGTGTTTATACAGAAATAACTTTTAAGTTGCTATTTAATATGAATGACTATTATGTATTTACATTTTTTCCACCAA
GTTTTGTATGGGTAAATGTTTTATTAAGTTTATTTGCAGTATTTATAGTTTTAAGAAGTGGTTATGCAAAAGCAAATAAA
AAACACTTAAGGATGAGAATGTAA

Upstream 100 bases:

>100_bases
CGTGGAGGCTTTGAAAAAGGAATTTTGCTAAAAGGTGTTAGTAAATAAATTTAGAGATAAAGTAAAGAACAATGAACAAA
TAAAAGGGAGTATGGGATAA

Downstream 100 bases:

>100_bases
AATGATTGTTGAAGAAATAAGAAAAAGACATTAGATAAAAATGCGAAGGAGCTTGATTAATTTCAGGCTCTTATTTTTTT
GAAGTTAAGCATAATCTATA

Product: beta-lactamase

Products: NA

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSNIMKRKKNLLKSVILIVALMGIAFSVFNVIKNKDNDYIDKLIEKYSPQGAAIAVIENGEITEVRNYGYSNIESKSLVN
NETQFKIASISKSITSYAVMKLVDEGKLNLDEPINTYLTKWKIPDTEFDENKLTLRTLMSHTSGITGSNEIGYESPLPTI
EDALKIRDIKLKREPGEVFEYSEFAGLGICQLIIEEVTGEKFEKYMEDEVFKKLGMNNTNYDNEIGDNLLAVPYAGINKQ
IKVTPIVMNGGGGVSTTASDLAKFTIELINYHNNGDGEMFKAQKNTESVGGKYGLGIIPRELKNGKTVYEHNGTLTGWNA
QMVMEPISKDGIVILTNSDKAFFLTYELMEKWGEKAVGEKVIDTKINTLVDMVYKCIAVLCAILTLLIIIFIIKVKKCKI
VLLERKKRNRKYLISAIFCTLLAVIYFVSVYTEITFKLLFNMNDYYVFTFFPPSFVWVNVLLSLFAVFIVLRSGYAKANK
KHLRMRM

Sequences:

>Translated_487_residues
MSNIMKRKKNLLKSVILIVALMGIAFSVFNVIKNKDNDYIDKLIEKYSPQGAAIAVIENGEITEVRNYGYSNIESKSLVN
NETQFKIASISKSITSYAVMKLVDEGKLNLDEPINTYLTKWKIPDTEFDENKLTLRTLMSHTSGITGSNEIGYESPLPTI
EDALKIRDIKLKREPGEVFEYSEFAGLGICQLIIEEVTGEKFEKYMEDEVFKKLGMNNTNYDNEIGDNLLAVPYAGINKQ
IKVTPIVMNGGGGVSTTASDLAKFTIELINYHNNGDGEMFKAQKNTESVGGKYGLGIIPRELKNGKTVYEHNGTLTGWNA
QMVMEPISKDGIVILTNSDKAFFLTYELMEKWGEKAVGEKVIDTKINTLVDMVYKCIAVLCAILTLLIIIFIIKVKKCKI
VLLERKKRNRKYLISAIFCTLLAVIYFVSVYTEITFKLLFNMNDYYVFTFFPPSFVWVNVLLSLFAVFIVLRSGYAKANK
KHLRMRM
>Mature_486_residues
SNIMKRKKNLLKSVILIVALMGIAFSVFNVIKNKDNDYIDKLIEKYSPQGAAIAVIENGEITEVRNYGYSNIESKSLVNN
ETQFKIASISKSITSYAVMKLVDEGKLNLDEPINTYLTKWKIPDTEFDENKLTLRTLMSHTSGITGSNEIGYESPLPTIE
DALKIRDIKLKREPGEVFEYSEFAGLGICQLIIEEVTGEKFEKYMEDEVFKKLGMNNTNYDNEIGDNLLAVPYAGINKQI
KVTPIVMNGGGGVSTTASDLAKFTIELINYHNNGDGEMFKAQKNTESVGGKYGLGIIPRELKNGKTVYEHNGTLTGWNAQ
MVMEPISKDGIVILTNSDKAFFLTYELMEKWGEKAVGEKVIDTKINTLVDMVYKCIAVLCAILTLLIIIFIIKVKKCKIV
LLERKKRNRKYLISAIFCTLLAVIYFVSVYTEITFKLLFNMNDYYVFTFFPPSFVWVNVLLSLFAVFIVLRSGYAKANKK
HLRMRM

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786574, Length=369, Percent_Identity=23.5772357723577, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI115533026, Length=193, Percent_Identity=30.0518134715026, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17550934, Length=301, Percent_Identity=23.5880398671096, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 55080; Mature: 54949

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIMKRKKNLLKSVILIVALMGIAFSVFNVIKNKDNDYIDKLIEKYSPQGAAIAVIENG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECC
EITEVRNYGYSNIESKSLVNNETQFKIASISKSITSYAVMKLVDEGKLNLDEPINTYLTK
CEEHHHHCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEE
WKIPDTEFDENKLTLRTLMSHTSGITGSNEIGYESPLPTIEDALKIRDIKLKREPGEVFE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCHHC
YSEFAGLGICQLIIEEVTGEKFEKYMEDEVFKKLGMNNTNYDNEIGDNLLAVPYAGINKQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCEEEECCCCCCCE
IKVTPIVMNGGGGVSTTASDLAKFTIELINYHNNGDGEMFKAQKNTESVGGKYGLGIIPR
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHCCCCCCCCCCCH
ELKNGKTVYEHNGTLTGWNAQMVMEPISKDGIVILTNSDKAFFLTYELMEKWGEKAVGEK
HHCCCCEEEECCCEEECCCHHHHHCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHH
VIDTKINTLVDMVYKCIAVLCAILTLLIIIFIIKVKKCKIVLLERKKRNRKYLISAIFCT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCHHHHHHHHHHH
LLAVIYFVSVYTEITFKLLFNMNDYYVFTFFPPSFVWVNVLLSLFAVFIVLRSGYAKANK
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
KHLRMRM
HHHCCCC
>Mature Secondary Structure 
SNIMKRKKNLLKSVILIVALMGIAFSVFNVIKNKDNDYIDKLIEKYSPQGAAIAVIENG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECC
EITEVRNYGYSNIESKSLVNNETQFKIASISKSITSYAVMKLVDEGKLNLDEPINTYLTK
CEEHHHHCCCCCCCCHHHCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHEE
WKIPDTEFDENKLTLRTLMSHTSGITGSNEIGYESPLPTIEDALKIRDIKLKREPGEVFE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCHHC
YSEFAGLGICQLIIEEVTGEKFEKYMEDEVFKKLGMNNTNYDNEIGDNLLAVPYAGINKQ
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCEEEECCCCCCCE
IKVTPIVMNGGGGVSTTASDLAKFTIELINYHNNGDGEMFKAQKNTESVGGKYGLGIIPR
EEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCHHHCCCCCCCCCCCH
ELKNGKTVYEHNGTLTGWNAQMVMEPISKDGIVILTNSDKAFFLTYELMEKWGEKAVGEK
HHCCCCEEEECCCEEECCCHHHHHCCCCCCCEEEEECCCCEEEEEHHHHHHHHHHHHHHH
VIDTKINTLVDMVYKCIAVLCAILTLLIIIFIIKVKKCKIVLLERKKRNRKYLISAIFCT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHCCCHHHHHHHHHHH
LLAVIYFVSVYTEITFKLLFNMNDYYVFTFFPPSFVWVNVLLSLFAVFIVLRSGYAKANK
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
KHLRMRM
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA